Clinical trials: Clinical Pain
Postsurgical Pain, Third Molar Extraction
Efficacy and Safety of APSCTC for the Treatment of Postsurgical Pain Due to Third Molar Extraction
The purpose of this study is to evaluate the efficacy of APSCTC compared to two active drugs in acute pain relief.
- Trial name
- CARLOTA (NCT04647435)
- Testing
- APSCTC, Toragesic®, Tramal®
- Where
- Brazil
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- Apsen Farmaceutica S.A.
Neuralgia
Home-based EEG Neurofeedback for Chronic Neuropathic Pain
In order to address the growing problem of chronic pain management in the UK, a proof of concept/feasibility open label cohort study has been devised to explore the effectiveness of a home-based self-administered…
- Trial name
- NCT05464199
- Testing
- Neurofeedback training
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life
Effects of Different Root Canal Filling Materials and Irrigation Agitation Techniques on Postoperative Pain in Teeth With Irreversible Pulpitis: A Randomized Clinical Trial
This clinical study is designed to evaluate the effects of different irrigation agitation techniques and root canal sealers on postoperative pain and oral health-related quality of life in patients with symptomatic irreversible…
- Conditions
- Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life, Symptomatic Irreversible Pulpitis, Endodontic Treatment
- Trial name
- NCT07859384
- Testing
- XP-Endo Finisher, EDDY, Passive Ultrasonic Activation
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Ankara University
Surgical Incision, Pain, Postoperative
Continuous Erector Spinae Plane Blocks to Treat Postoperative Pain After Open Gynecologic Procedures Via a Low Transverse (Pfannenstiel) Incision
Open gynecologic surgery can be very painful. With the goal of minimizing the use of opioids (with undesired side effects and potential for abuse), the investigators often administer a type of peripheral nerve block in which the…
- Conditions
- Surgical Incision, Pain, Postoperative, Pain, Acute
- Trial name
- NCT05082155
- Testing
- Bupivacaine 0.25%, Normal Saline
- Where
- United States
- Sponsor
- University of California, San Diego
Sacroiliac Joint Pain
LINQ® Procedure vs. Conventional Medical Management for Sacroiliac Dysfunction
The objective of this clinical evaluation is to assess the safety and effectiveness of LINQ fusion procedure for treatment of sacroiliac joint (SIJ) dysfunction compared to Conservative Medical Management (CMM).
- Trial name
- LINQT (NCT07558278)
- Testing
- Bone Allograft, Conventional Medical Management (CMM)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- PainTEQ, LLC
Neck Pain
Influence of Adding High Power Pain Threshold Ultrasound to Traditional Therapy on Axioappendicular Muscles Amplitude and Fatigue in Mechanical Neck Pain Randomized Clinical Trials
The purpose of this study will investigate the effect of adding high power pain threshold ultrasound to traditional therapy on axioappendicular muscles amplitude and fatigue in neck pain
- Trial name
- MNP (NCT05540093)
- Testing
- high power pain threshold ultrasound, traditional therapy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Pain
A Clinical Study of the Combination of SHR8554 Injection and SHR0410 Injection for the Treatment of Pain After Abdominal Surgery.
The primary objective is to evaluate the analgesic efficacy of the combination of SHR8554 injection and SHR0410 injection compared with SHR8554 injection in patients with acute postoperative pain following abdominal surgery
- Trial name
- NCT05470049
- Testing
- SHR8554 Injection and SHR0410 Injection
- Volunteers
- 108 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Angina Pectoris
Long-term Results Following Endoscopic Vein Harvesting in Coronary Artery Bypass Surgery
Vena saphena magna is still frequently used as graft material in coronary artery bypass grating(CABG, and vein grafts can harvest with either the conventional open technique (Ovh = open vein harvesting), or with less invasive…
- Trial name
- NCT01480726
- Testing
- Surgery
- Where
- Denmark
- Volunteers
- 132 people
- Sponsor
- Aalborg University Hospital
Labor; Prolonged, Second Stage, Episiotomy Wound
The Impact of Different Skin Suture Methods in Episiotomy Repair on Healing and Pain
Episiotomy is the intentional incision of the perineum during vaginal birth in order to accelerate the active phase of labor. This study aimed to compare various skin closure techniques in episiotomy repair.
- Trial name
- NCT06379048
- Testing
- Mattress Suturing, Primary Suturing, Continuous Subcutaneous Suturing
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Pain
Comparing Intravenous Hydromorphone to Usual Care
In this randomized controlled trial, 2 mg intravenous (IV) hydromorphone will be more efficacious than usual care (usual care is analgesic management according to the judgment of the attending physician caring for that patient)…
- Trial name
- NCT01429298
- Testing
- Hydromorphone, Usual care
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pain, Chronic, Education
The Effect of Pain Education on Chiropractic Students' Understanding of Chronic Pain
Chronic pain is the leading cause of disability worldwide affecting just under 28 million people in the UK. Chronic pain conditions require a biopsychosocial rather than a biomedical model of care.
- Trial name
- NCT05359900
- Testing
- Pain neuroscience education, Red Flag Education
- Where
- 4 sites in United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Teesside University
Chronic Musculoskeletal Pain, Clinical Communication
Development and Evaluation of an Educational Program for the Management of Chronic Musculoskeletal Pain
A controlled randomized study will be conducted to assess the effectiveness of the educational program before and after its implementation.
- Trial name
- NCT06653114
- Testing
- Education in Chronic Musculoskeletal Pain, Education in Communication Skills
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Endodontically Treated Teeth
The Effect of Root-canal Medicaments on Post-operative Pain in Re-treatment Cases
This randomized clinical trial compares the effects of intracanal medicaments on the incidence of postoperative pain and flare-up in asymptomatic retreatment cases.
- Trial name
- NCT05052814
- Testing
- root canal medicament-calcium hydroxide, root canal medicament-chlorhexidine gel, root canal medicament-calcuim hyroxide &chlorhexidine ge
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Patellofemoral Pain
Strength or Power Training for Patellofemoral Pain
The objective of this study is to compare a novel 6-week strength training rehabilitation incorporating power exercises (STRIPE) program to a standard of care (SOC) program on short-term and long-term pain, subjective function…
- Trial name
- STRIPE (NCT05403944)
- Testing
- Standard of Care Rehabilitation (SOC), Strength Training Rehabilitation Incorporating Power Exercises (STRIPE)
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- University of Connecticut
Asymptomatic Vital Mandibular Molar Teeth
The Effect of Two Different Root Canal Sealers on Postobturation Pain and Clinical and Radiographical Outcome After Two-year Follow-up
Post-obturation pain evaluation(Part 1): One hundred asymptomatic mandibular molar teeth with vital pulp were randomly assigned into two groups according to the sealer used MTA Fillapex (Angelus Odontologica Industries SA…
- Trial name
- NCT05266599
- Testing
- MTA Fillapex root canal sealer, AH Plus root canal sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Influenza, Human, Arthralgia
An Intravenous (IV) Zanamivir Pharmacokinetics (PK) Study in Hospitalized Neonates and Infants With Influenza Infection
Influenza infection is an important public health priority, with seasonal outbreaks and pandemics causing considerable global morbidity and mortality.
- Trial name
- NCT04494412
- Testing
- Zanamivir
- Where
- 6 sites in Italy, Poland and 1 more
- Volunteers
- 8 people
- Sponsor
- GlaxoSmithKline
Appendicitis, Diagnoses Disease
Evaluation of Pressure Algometry in the Clinical Assessment of Acute Abdominal Pain in Children
In this retrospective observational case study, the investigators review the clinical experience with pressure-pain algometry in children with suspected appendicitis.
- Conditions
- Appendicitis, Diagnoses Disease, Pediatric ALL
- Trial name
- NCT04688463
- Volunteers
- 427 people
- Sponsor
- University of Manitoba
Neuropathic Pain, Pain
Clinical Effect of LG Medipain for Managing Chronic Pain Disorders
Scrambler Therapy is a type of non-invasive neuromodulation. According to the researches that studied the effects of the existing Scrambler therapy, 10 times of Scrambler Therapy showed a significant pain relief lasting for more…
- Conditions
- Neuropathic Pain, Pain, Refractory Pain, Chronic Pain
- Trial name
- NCT05165901
- Testing
- Scrambler Therapy
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Jeeyoun Moon
Shoulder Pain, Shoulder Injuries
Efficacy of a Criteria Based Clinical Pathway for Rehabilitation of Shoulder Injuries
The goal of this clinical trial is to compare the current standard of care for rehabilitation of non-operative shoulder injuries to a novel, criteria-based approach (CRISP).
- Trial name
- CRISP (NCT06536114)
- Testing
- CRISP: Criteria-Based Approach for the Rehabilitation for Non-Operative Shoulder Injuries, Standard of Care
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- United States Naval Medical Center, San Diego
Postoperative Pain
Postoperative Pain of Rotary Versus Reciprocating Motions of Two Single Files
An equivalent parallel randomized clinical trial was approved by the local University Committee of Ethics. 260 children with necrotic primary molars were allocated into 2 equal groups (82 children per group).
- Trial name
- NCT05059171
- Testing
- OneSahpe single file, WaveOne Gold single file
- Where
- Egypt
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Minia University
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