Clinical trials: Clinical Pain
Postoperative Pain
The Transversus Abdominis Plane Block: A Prospective Randomized Clinical Trial Using EXPAREL.
The purpose of the study is to evaluate the effectiveness of EXPAREL in a transversus abdominis plane block by assessing the demand of postoperative narcotic, length of hospital stay and incidence of postoperative complications.
- Trial name
- NCT02263963
- Testing
- Exparel, TAP Block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Corewell Health West
Arthroplasty, Hemiarthroplasty
A Post-Market Clinical Evaluation of the ReUnion Reversible Fracture (RFX) System
This investigation is a prospective, multi-center clinical investigation. It is anticipated that a total of one hundred (100) subjects will be enrolled at approximately 5-10 sites.
- Conditions
- Arthroplasty, Hemiarthroplasty, Shoulder Pain
- Trial name
- NCT04089371
- Testing
- ReUnion Total Shoulder Arthroplasty (TSA), ReUnion Reverse Shoulder Arthroplasty (RSA)
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Stryker Trauma and Extremities
Complex Regional Pain Syndromes
Thoracic Sympathetic Ganglion Block With Botulinum Toxin Type A
Thoracic sympathetic ganglion block is a percutaneous procedure that paralyzes the action of sympathetic nerves transiently by injecting a local anesthetic around the ganglion.
- Trial name
- NCT06470581
- Testing
- Botulinum toxin A
- Volunteers
- 78 people
- Sponsor
- Seoul National University
Post Operative Pain, Apical Periodontitis
Influence of Sonic Activation of Root Sealers on Post-Operative Pain
Aim: This clinical study aims to compare post-operative pain after single-visit root canal treatment of teeth with asymptomatic apical periodontitis using epoxy-resin based AH Plus and calcium silicate based Endosequence BC…
- Trial name
- NCT06403293
- Testing
- Root canal treatment (AH Plus-NA), Root canal treatment (AH Plus-EA), Root canal treatment (BC-NA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Premenstrual Syndrome, Menstrual Pain
A Clinical Study to Assess the Effect of a Dietary Supplement on Menstrual Cycle Symptoms
This is a single-group, virtual clinical trial evaluating the effects of a daily dietary supplement (DITTO Cycle Supplement) on menstrual cycle symptoms across three menstrual cycles.
- Trial name
- NCT07267728
- Testing
- DITTO Cycle Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muse Nutrition Ltd
Infertility
Lidocaine Patch Versus Intravenous Lidocaine in Pain Relief After Laparoscopy
To evaluate the efficacy of lidocaine patch applied around wound in laparoscopic gynecologic surgery in reduction of postoperative pain and illus compared to intravenous lidocaine infusion and placebo.
- Trial name
- NCT04506034
- Testing
- lidocaine patches, IV lidocaine, IV saline infusion
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Spinal Cord Injuries
Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury
Spinal cord injury (SCI) is associated with severe neuropathic pain that is often refractory to all pharmacological intervention.
- Trial name
- NCT04379011
- Testing
- Brivaracetam
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Migraine
Evaluation of Pain Thresholds in Migraine Patients After Inhalation of Essential Oils: a Randomized Clinical Trial
This study will test whether inhaling essential oils can change how sensitive people with migraine are to pressure pain. Participants will be allocated to inhale lavender, peppermint, a combination of both, or a control solution…
- Trial name
- NCT07493434
- Testing
- Lavander essential oil, Peppermint essential oil, Lavandula angustifolia and Mentha Piperita
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Knee Osteoarthritis
The Impact of Therapeutic Alliance in the Rehabilitation of Knee Osteoarthritis.
The therapeutic alliance (TA) is the working relationship or positive social bond between the patient and the therapist. TA is based on collaboration, communication, empathy of the therapist and mutual respect.
- Trial name
- ALLIANCE (NCT04390932)
- Testing
- Enhanced TA, Limited TA, Therapeutic exercise protocol.
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- Universidad Catolica de Temuco
Morbid Obesity
VAS Correlation With BMI
The aim of the study is to observe if any correlation between Body mass index and VAS values exists in patients who has gone under abdominal surgery.
- Trial name
- NCT02017314
- Testing
- Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Nonspecific Chronic Low Back Pain
Patient Education and Motor Control Exercise Among Rural Community-dwelling Adults With Chronic Low Back Pain
Low back pain (LBP) is the leading cause of years lived with disability globally with increasing concern about its impact in low- and middle-income countries like those situated in Africa where most people are living in rural…
- Trial name
- NCT03393104
- Testing
- Motor Control Exercise, Patient Education
- Where
- Nigeria
- Volunteers
- 120 people
- Sponsor
- Bayero University Kano, Nigeria
Acute Pain
Ketamine for Pain in the Emergency Department
This study will prospectively compare the mean Numerical Rating Scale (NRS) pain score reduction amongst three recommended dosing strategies of intravenous ketamine (0.1 mg/kg, 0.2 mg/kg, and 0.3mg/kg) for acute pain in the…
- Trial name
- NCT03896230
- Testing
- Ketamine Injectable Product
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Hackensack Meridian Health
Back Pain
Could a Simple Information Booklet Modify Low Back Pain Patients Beliefs After Lumbar Discectomy?
The purpose of this study is to translate and assess an evidence based educational booklet on low back pain patients beliefs after lumbar discectomy.
- Trial name
- NCT00761111
- Testing
- Assessment of the Your Back Operation
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Intravenous Propofol Injection
Effect of Dexmedetomidine on Pain Due to Propofol Injection
Propofol is commonly used IV anesthetic, it has been formulated in a concentration of 10 mg/ml in a fat emulsion consisting of 10% soybean oil (long-chain triglycerides).
- Trial name
- NCT01463332
- Testing
- I.V injection of 10 ml normal saline, I.V injection with 0.25mic/kg of dexmedetomidine, I.V injection of 0.50mic/kg of dexmedetomidine
- Volunteers
- 150 people
- Sponsor
- KVG Medical College and Hospital
Musculoskeletal Diseases or Conditions, Neurologic Disorder
Clinical Course of Patients Receiving Physiotherapy Services in Primary Health Care
Background: Physiotherapists (PTs) in primary health care manage patients with a large variation in medical diagnosis, age, functional status, disability and prognosis.
- Conditions
- Musculoskeletal Diseases or Conditions, Neurologic Disorder, Widespread Chronic Pain, Psychosomatic Disorder
- Trial name
- FYSIOPRIM (NCT03626389)
- Testing
- Physiotherapy
- Where
- 2 sites in Norway
- Volunteers
- 4,985 people
- Sponsor
- University of Oslo
Osteoarthritis, Arthritis, Rheumatoid
Low Dose Naltrexone for Chronic Pain From Arthritis
Over 100 million Americans report chronic pain. Veterans are disproportionately affected for multiple reasons, including injuries and post-traumatic stress disorder.
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Arthritis, Psoriatic
- Trial name
- LDN-VA (NCT03008590)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Dyspareunia
Trans-perineal Trigger Point Dry Needling for Chronic Pelvic Pain
Chronic Pelvic Pain (CPP) are around 10% of gynaecology referrals.Non-relaxing pelvic floor dysfunction (NRPFD) is an under-appreciated cause for CPP with dyspareunia where no other pathology exists.
- Trial name
- NCT02795026
- Testing
- Manual therapy, Trigger point dry needling
- Where
- 2 sites in Ireland
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Cork University Hospital
Pain, Postoperative
Arthroscopic Anterior Cruciate Ligament Reconstruction: A Comparison of Three Catheter Placement Positions
This investigation will evaluate the subjective effect on postoperative pain of three catheter placements in the knee: 1. intraarticular infusion only, 2. patellar tendon harvest site only, 3.
- Trial name
- NCT00178178
- Testing
- Breg Pain Care 3000 Catheter, Bupivicaine 0.5%
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Pain
Clinical Effects of Gelified Ethanol Application in Cervical Disc Hernia
The aim of the study is to evaluate the clinical effects of Discogel® Radiopaque Gelified Ethanol as therapeutic substance for nucleolysis application in the patients with cervical disc hernia who had chronic pain and weakness on…
- Trial name
- NCT02834676
- Testing
- Gelified Ethanol
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Sakarya University
Chronic Pain, Cerebral Palsy
Pain Classification in Caregivers for Children With Cerebral Palsy
The care of children with Cerebral Palsy is a process that continues for many years. Individuals who take care of them experience musculoskeletal pain due to the difficulties they experience and face pain that becomes chronic…
- Conditions
- Chronic Pain, Cerebral Palsy, Musculoskeletal Pain, Caregivers
- Trial name
- NCT04883489
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
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