Clinical trials: Clinical Pain
Osteoarthritis, Hip
Clinical Assessment of Two Manipulative Protocols in Treatment of Hip Osteoarthritis
Purpose of this study is to examine the effect of chiropractic adjusting (manipulative therapy) and rehabilitation on hip osteoarthritis (hip OA) in older adults.
- Trial name
- NCT00523172
- Testing
- manual or manipulative therapy, Manual / Manipulative Therapy, Supportive Care
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 120 people
- Sponsor
- Cleveland Chiropractic College
Total Laparoscopic Hysterectomy
Clinical Study of Equivalent Doses of Oxycodone or Tegileridine on Patients Undergoing Gynecological Laparoscopic Hysterectomy
This randomized, double-blind, controlled study aims to evaluate the efficacy and safety of Tegileridine or Oxycodone for postoperative analgesia in patients undergoing Total Laparoscopic Hysterectomy（TLH）.
- Trial name
- NCT07326683
- Testing
- Tegileridine (tegileridine fumarate injection, IV), Oxycodone（Oxycodone Hydrochloride Injection，IV）
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Xin Chen
Gingival Pigmentation
Effect of Non-eugenol Periodontal Pack With and Without PRF on Post-operative Pain and Wound Healing After Gingival Depigmentation
In an era where less than ideal esthetics is not accepted, the request for esthetic procedures is widely sought after. Melanin, a brown pigment, is the most common natural pigment contributing to endogenous pigmentation of…
- Trial name
- NCT04495205
- Testing
- PRF under non-eugenol containing periodontal pack, Non-eugenol containing periodontal pack
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low Back Pain, Chronic Disease
Myofascial Release and Kinesio Taping on Autonomic Nervous System in Low Back Pain
The purpose of this current randomized clinical trial is to determine the effects of myofascial soft tissue release and kinesio taping on disability, pain, quality of life, autonomic nervous system and oxidative stress indicators…
- Trial name
- I (NCT02067494)
- Testing
- Myofascial Soft Tissue Release, Kinesio taping treatment
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Universidad de Almeria
Chest Pain, Coronary Artery Disease
A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (or ASGES) in Primary Care Settings
The PRESET Registry--A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (Age/Sex/Gene Expression score - ASGES) in Real World Clinical Care Settings (PRESET)--was designed as an observational…
- Conditions
- Chest Pain, Coronary Artery Disease, Cardiovascular Diseases, Coronary Heart Disease
- Trial name
- PRESET (NCT01677156)
- Testing
- CORUS CAD (ASGES)
- Where
- 13 sites in United States
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- CardioDx
Rectal Cancer, Radiotherapy, Anal Pain
Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal Skin
Background: According to GLOBOCAN 2022 statistics, colorectal cancer has become the third most common cancer disease worldwide, and also the second leading cause of death.
- Conditions
- Rectal Cancer, Radiotherapy, Anal Pain, Acute Radiation Dermatitis, Anal Canal
- Trial name
- NCT06837831
- Testing
- Control group, Experimental group
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Qianfoshan Hospital
Myofascial Pain Syndrome (Upper Trapezius)
Ultrasound-Guided Dry Needling, Lidocaine Injection, and Oxygen-Ozone Injection for Myofascial Pain Syndrome
Prospective, assessor-blinded, three-arm randomized controlled trial comparing ultrasound-guided dry needling, lidocaine injection, and oxygen-ozone injection in patients with myofascial pain syndrome (MPS) of the upper trapezius…
- Trial name
- USDLO-MPS (NCT07738783)
- Testing
- Dry Needling, Lidocaine Injection (1%, 2 mL), Oxygen-Ozone Injection (10 μg/mL, 5 mL)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Derince Training and Research Hospital
Arthritis, Arthritis/Arthrosis
Combining Virtual Reality and Hypnosis to Alleviate Chronic Pain in Elderly Patients with Hand Arthritis
The goal of this pilot randomized clinical trial is to test the efficacy of an intervention combining virtual reality and hypnosis on decreasing pain and improving quality of life in elderly patients with hand arthritis.
- Conditions
- Arthritis, Arthritis/Arthrosis, Arthritis, Rheumatoid, Elderly
- Trial name
- VRHArthrisis (NCT06833905)
- Testing
- Virtual reality: Beach, Virtual Reality: Forest, Hypnosis: Magic Hand
- Volunteers
- 80 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Somatic Symptom Disorder (DSM-V)
Effect of Venlafaxine Versus Dosulepin in Pain Predominant Somatic Symptom Disorder
Somatic symptom disorder (SSD) is marked by persistent physical complaints, often involving pain, alongside excessive thoughts or behaviors related to health, which substantially disrupt daily functioning.
- Trial name
- NCT06803485
- Testing
- Venlafaxine, Dosulepin
- Where
- India
- Volunteers
- 84 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Pain, Elbow
Radial Nerve Block for Treatment of Tennis Elbow
Background: Lateral epicondylitis, or tennis elbow, is a common musculoskeletal disorder that causes pain and functional limitation.
- Trial name
- NCT03262623
- Testing
- Radial nerve block
- Where
- Lebanon
- Volunteers
- 50 people
- Sponsor
- Makassed General Hospital
Post-operative Pain
Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.
To compare the effect of cryotherapy versus ketorolac tromethamine irrigating solutions used as a final flush in single visit endodontic treatment in mandibular molars, with symptomatic irreversible pulpitis and apical…
- Trial name
- NCT04733326
- Testing
- Ketorolac Tromethamine, Cryotherapy, Saline
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain
Anrikefon Injection for Postoperative Analgesia in Thoracoscopic Lung Surgery: A Randomized, Double-Blind, Active-Controlled, Parallel-Group, Single-Center Clinical Study
This is a randomized, double-blind, active-controlled clinical study evaluating the efficacy and safety of Anrikefon (HSK21542) Injection for patient-controlled analgesia (PCA) in patients undergoing thoracoscopic lung surgery.
- Trial name
- NCT07810413
- Testing
- Anrikefon Injection, Sufentanil Citrate Injection
- Volunteers
- 88 people
- Sponsor
- The First People's Hospital of Lianyungang
Clinical Evaluation Including Pain and Swelling
Clinical and Radiographic Evaluation in Pulpotomy of Primary Molars Using Protooth Vs. MTA
The aim of the study is to evaluate the clinical and radiographic success in pulpotomy using novel fast-setting calcium silicate cement (Protooth) versus MTA in exposed primary molars.
- Trial name
- NCT04710160
- Testing
- Novel fast-setting calcium silicate cement (Protooth)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fibromyalgia
Quetiapine (Seroquel XR) for the Treatment of Fibromyalgia: a Clinical and Mechanistic Pilot Study
This is a double-blind, randomized, placebo-controlled trial measuring the impact of quetiapine on clinical and experimental measures of pain in fibromyalgia and its biochemical correlates.
- Trial name
- NCT00983320
- Testing
- quetiapine
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Université de Sherbrooke
Nociceptive Pain, Pupillary Light Reflex Lost
Clinical Trial Using Pupillometry to Measure Nociception in Healthy Volunteers.
Pupillometry has been used in healthy volunteers to investigate the usefulness of the pupil light reflex as an indicator of pain intensity on pressure as a nociceptive stimulus.
- Conditions
- Nociceptive Pain, Pupillary Light Reflex Lost, Healthy, Pain, Procedural
- Trial name
- NCT04864340
- Testing
- CE marked medical device, Algometer, Comparator
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Anesthesia
Comparison of Different Analgesia-Monitors in Tracing Unconscious Pain Sensations
Until today there is no standard-monitoring to specifically reflect the analgesic component of general anesthesia. Quality and safety of general anesthesia are of major clinical importance and can be improved by limiting the…
- Trial name
- AMUPS (NCT02429960)
- Testing
- Analgesia monitor (PhysioDoloris®), Analgesia monitor (SPI®), Analgesia monitor (AlgiScan®)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Tooth Whitening, Sensitivity
Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening
Introduction: The pain sensitivity associated with whitening is the main problem reported by patients during dental whitening, and the use of desensitizing dentifrices is an alternative for the treatment of sensitivity.
- Trial name
- NCT03019224
- Testing
- Selection and preparation of the volunteers, Evaluation of the tooth color, Relative isolation
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Coronary Artery Diseases, Valvular Heart Diseases
Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery
Reiki is an energy-based healing therapy using light touch. Manual therapy is a technique using light effleurage. These complimentary healing services are utilized to promote relaxation, sleep, improve emotions, and decrease…
- Trial name
- NCT05853250
- Testing
- Reiki/manual therapy
- Where
- United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Necrotic Teeth
Antibacterial Effect and Post-operative Pain Following Various Techniques of Intracanal Heating of NaOCL
The goal of this clinical trial is to is to assess the antibacterial effect of sodium hypochlorite heated inside root canals of necrotic teeth using various activation techniques The main question it aims to answer is: Does the…
- Trial name
- NCT07420920
- Testing
- System-B, Ultrasonic activation
- Volunteers
- 36 people
- Sponsor
- Misr University for Science and Technology
Dental Anxiety, Anxiety Disorder
Lavender Oil Inhalation Help to Overcome Dental Anxiety Among Children
The purpose of this study is to investigate the impact of lavender oil (Lavandula angustifolia) on anxiety, pain and vital signs (blood pressure, heart rate and saturation) among children planned to undergone surgical…
- Conditions
- Dental Anxiety, Anxiety Disorder, Aromatherapy
- Trial name
- NCT04115891
- Testing
- Anxiety scale, Pain scale - 1, Pain scale - 2
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
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