Clinical trials: Clinical Pain
Instability; Back
Neuromuscular Electrical Stimulation and Motor Control
Phase I, this study aims to:- 1. Establish intra- and inter-rater reliability and minimal detectable change of ultrasound imaging measurement 2.
- Trial name
- NCT03786627
- Testing
- Combined NMES and motor control
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Severe Knee Pain, Severe Knee Disability
Persona Revision Knee System EMEA PMCF Study
The purpose of this post-market clinical follow-up study is to confirm the long-term safety, performance and clinical benefits of the Persona Revision Knee System Implants and Instrumentation in revision Total Knee Arthroplasty.
- Conditions
- Severe Knee Pain, Severe Knee Disability, Revision Arthroplasty
- Trial name
- NCT07843966
- Where
- 2 sites in Denmark, Spain
- Volunteers
- 238 people
- Sponsor
- Zimmer, GmbH
Pain, Post Operative, Quality of Life
Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft
The goal of this randomized clinical trial is to compare patient-reported pain and oral health-related quality of life during the first postoperative week following extraction and bone graft surgery in patients who received…
- Trial name
- NCT05919745
- Testing
- Ibuprofen 600 mg, Acetaminophen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marquette University
Post-Operative Pain, Acute Pain
Clinical Study to Evaluate the Effectiveness, Safety, and Tolerability of Oxymorphone Immediate Release (IR) Oral Liquid in Post Surgical Pediatric Subjects
The purpose of the study is to evaluate the efficacy, tolerability, safety and pharmacokinetics of Oxymorphone HCl as an analgesic for acute moderate to severe post-operative pain in pediatric subjects.
- Trial name
- NCT02687451
- Testing
- Oxymorphone HCl
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Chronic Pain
eVISualisation of Physical Activity and Pain (eVIS) for Patients With Chronic Pain
Introduction: Living with chronic pain often involves negative consequences. Interdisciplinary Pain Rehabilitation Programs (IPRPs), a subset of Interdisciplinary Treatment (IDT) includes physical activity and exercise and is…
- Trial name
- eVIS (NCT05009459)
- Testing
- eVIS
- Where
- Sweden
- Volunteers
- 280 people
- Sponsor
- Dalarna University
Bruises
Patients Preference With Self-Injection: The PRISM Study
The purpose of this study is to determine which short-acting blood thinner (low-molecular-weight heparin [Enoxaparin] or unfractionated heparin) is associated with less discomfort and bruising when given as a subcutaneous (under…
- Trial name
- NCT00253396
- Testing
- Unfractionated heparin, Enoxaparin
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Lumbar Disc Herniation
The Efficacy of Clinical Pilates Exercises on Individuals With Lumbar Disc Herniation
The aim of the study is to determine the effects of clinical Pilates Exercises on the level of pain, functional status, flexibility, static and dynamic endurance of the truncus muscles and quality of life in patients with lumbar…
- Trial name
- NCT03198273
- Testing
- Clinical pilates exercises, physiotherapy program
- Where
- Cyprus
- Volunteers
- 88 people
- Sponsor
- Eastern Mediterranean University
Pain, Postoperative
Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)
Video-assisted thoracoscopic surgeries (VATS) include severe postoperative acute pain which is also a predictor of chronic pain.
- Trial name
- VATS (NCT02302586)
- Testing
- Thoracic paravertebral block (TPVB), Patient Controlled Analgesia (IV PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Knee Osteoarthritis
Clinical Evaluation of the Levitation Knee Brace
Osteoarthritis (OA) is a debilitating disease affecting approximately 1/3 of Canadians over the age of 25. Knee OA typically involves at least 2 of 3 compartments in the knee joint.
- Trial name
- NCT05543486
- Testing
- Levitation 2 Tri-Compartment Offloader (TCO) knee brace, Knee sleeve
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University of Calgary
Femoracetabular Impingement, Hip Arthroscopy
Efficacy of Ketorolac for Postoperative Pain Management in Hip Arthroscopy
The goal of this clinical trial is to learn whether the medication ketorolac can help manage pain after hip arthroscopy as well or better than the standard opioid-based pain medications.
- Trial name
- NCT07037888
- Testing
- Ketorolac, Control (Standard treatment), Omeprazole
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Temporomandibular Joint Disorders
The Effect of Piroxicam Addition During Arthrocentesis on Mouth Opening and Postoperative Pain
TMDs is an ancient condition discovered thousands of years ago. Historians state that the ancient Egyptians were the first who managed TMDs. They manually treated joint dislocation by away similar to ours nowadays.
- Trial name
- NCT06508203
- Testing
- arthrocentesis with lactate ringer only, arthrocentesis with lactate ringer followed by injection with piroxicam 2 ml (40mg)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chronic Pain
Mechanistic Study of Personalized rTMS in Chronic Pain
Previous research has demonstrated that repetitive magnetic brain stimulation can be an effective adjunctive treatment for several conditions, including chronic pain.
- Trial name
- PRECISE-Pain (NCT07266103)
- Testing
- Classical repetitive trancranial magnetic stimulation to M1, Personalized Target Arm
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Aalborg University
Greater Trochanteric Pain Syndrome
Evaluation of TENEX for Greater Trochanteric Pain Syndrome (GTPS)
The objective of this study is to evaluate how an ultrasound-guided percutaneous procedure, TENEX, can help people with chronic hip pain resulting from a condition called Greater Trochanteric Pain Syndrome (GTPS) and to…
- Trial name
- RCT GTPS (NCT05710627)
- Testing
- TENEX
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Montefiore Medical Center
Lumbar Spinal Stenosis
Study Evaluating the Safety and Effectiveness of the FLEXUS(TM) Interspinous Spacer
The purpose of this investigation is to evaluate the safety and effectiveness of the FLEXUS™ Interspinous Spacer as compared to the XSTOP® Spacer for the treatment of patients who are suffering from lumbar spinal stenosis at one…
- Trial name
- NCT01156675
- Testing
- FLEXUS(TM) Interspinous Spacer, XSTOP® Interspinous Spacer
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Globus Medical Inc
Pain
Bupivacaine Pain Pumps to Decrease Mastectomy Post-Operative Pain
This double-blind, randomized, controlled clinical trial comparing patient-reported pain and pain medication/narcotic use between patients randomized to treatment (bupivacaine) or placebo (saline) delivered via pain pump to the…
- Trial name
- NCT01494259
- Testing
- Bupivacaine, Saline
- Where
- United States
- Sponsor
- Johns Hopkins University
Neck Pain, Chronic Pain
Manual Therapy and Exercise With Mixed Reality With Hololens® Exercise Protocol in Chronic Neck Pain Patiens.
Currently, cervical pain is the second most frequent musculoskeletal disorder, which generates an important impact on the function and quality of life.
- Trial name
- NCT03903380
- Testing
- Manual Therapy and Usual care exercise protocol for neck pain, Manual Therapy and Augmented reality exercise protocol
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Centro Universitario La Salle
Back Pain, Instability Lumbar Spine
Relative Stiffness of Lumbar Spine and Hamstrings Muscle Stretching
The purpose of this study is to investigate the effect of lumbopelvic stabilization on hamstrings muscle stretching in individuals with history of low back pain suspected to have a clinical lumbar instability.
- Conditions
- Back Pain, Instability Lumbar Spine, Muscle Tightness
- Trial name
- NCT03787979
- Testing
- Lumbopelvic stiffening technique, Lumbopelvic relaxing technique
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Distal Radius Fracture Reduction
Music During the Reduction of Distal Radius Fractures as an Adjunctive Therapy for Pain and Anxiety Management.
Fractures of the distal end of the radius are one of the most frequent fractures diagnosed in the emergency room. The initial management, and in many cases definitive, is carried out through manipulation, closed reduction and…
- Trial name
- NCT05974384
- Testing
- No Music, Music
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Corporacion Parc Tauli
FBSS
Stimwave HF SCS Pilot Study
The purpose of this study is to observe the efficacy of stimulation on over all pain relief as reported in an initial cohort of 6 patients treated with the Freedom High Frequency Spinal Cord Stimulator (SCS) System for low back…
- Trial name
- HFSCS (NCT02787252)
- Testing
- Implant procedure, Freedom Spinal Cord Stimulation System
- Where
- Belgium
- Volunteers
- 6 people
- Sponsor
- Curonix LLC
Dental Pulp Necrosis
Comparison Between Reciproc and Protaper Next
Comparing the postoperative pain resulting after mechanical instrumentation using Reciproc reciprocating files versus that resulting after using ProTaper Next rotary files in asymptomatic necrotic molars.
- Trial name
- NCT02946099
- Testing
- Reciproc files in reciprocating motion, ProTaper Next files in continuous rotary motion
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
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