Clinical trials: Clinical Pain
Orthodontic Appliance Complication, Oral Mucositis
L Brevis for Traumatic Oral Lesions in Orthodontic Patients
Introduction: Traumatic oral lesions are common in the beginning of the orthodontic treatment, and pathogenic oral bacteria might be involved.
- Conditions
- Orthodontic Appliance Complication, Oral Mucositis, Bacterium; Agent
- Trial name
- NCT04398511
- Testing
- L brevis
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade de Passo Fundo
Temporomandibular Joint Disorders
Miofascial Release and Exercises Therapy in the Treatment of Temporomandibular Disorders
Objectives: The aim of this research is to compare the effectiveness of myofascial release therapy and exercise therapy on pain, quality of sleep, anxiety, trigger points, and joint sounds in individuals with temporomandibular…
- Trial name
- NCT02540863
- Testing
- myofascial release protocol and Rocabado exercise therapy, exercise therapy
- Volunteers
- 64 people
- Sponsor
- Universidad de Almeria
Greater Trochanteric Pain Syndrome, Gluteal Tendinopathy
Comparing Standard Care Approaches for Greater Trochanteric Pain Syndrome in General Practice
Pain on the outside of the hip, known as greater trochanteric pain syndrome (GTPS), is a common problem. It is caused by irritation of the tendons that attach the buttock muscles to the hip bone.
- Conditions
- Greater Trochanteric Pain Syndrome, Gluteal Tendinopathy, Lateral Hip Pain
- Trial name
- NCT07848971
- Testing
- Patient advice, Patient advice plus exercise, Patient advice plus exercise plus corticosteroid injection
- Where
- 2 sites in Denmark
- Volunteers
- 192 people
- Sponsor
- Malene Kjær Bruun
Cesarean Section Complications
Lidocaine Patch Versus Intravenous Lidocaine in Pain Relief After Cesarean Section
To evaluate the efficacy of lidocaine patch applied around wound in reduction of postoperative pain and illus compared to intravenous lidocaine infusion and placebo after cesarean section.
- Trial name
- NCT04505644
- Testing
- lidocaine patch, IV lidocaine
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Aswan University Hospital
Heart; Surgery, Heart, Functional Disturbance as Result
Multifunctional Approach in Cardiac Surgery
Postoperative pain and swallowing disorders are complex, multifactorial phenomenon that frequently occur after cardiac surgery. Preoperative anxiety and the interaction between sex and other sociocultural factors may predict…
- Trial name
- TITANIC (NCT05824598)
- Testing
- Multifunctional rehabilitation treatment
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age
Virtual Menstrual Pain Approaches in Females
This research study is testing two self-care approaches that may help prevent or reduce period pain in young females with recurrent painful menstrual cramps.
- Conditions
- Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age, Mental Disorder, Digital Health
- Trial name
- AABQ (NCT07497711)
- Testing
- Virtual Auricular Acupressure, Virtual Baduanjin Qigong Exercise, Self Education
- Where
- Singapore
- Volunteers
- 145 people
- Sponsor
- Nanyang Technological University
Chronic Neck Pain
Effectiveness and Cost-effectiveness of Doin (Conduction Exercise) for Chronic Neck Pain
A pilot multicenter randomized controlled trial will be conducted to evaluate the clinical effectiveness, cost-effectiveness, and safety of Doin (conduction exercise) with acupuncture for chronic neck pain patients compared to…
- Trial name
- NCT03009071
- Testing
- Doin (conduction exercise), Acupuncture
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Jaseng Medical Foundation
Pulpitis - Irreversible, Pain, Postoperative
Comparison of Calcium Silicate-based Sealer and Epoxy Resin-based Sealer
Background: Sealers have been concerned with obturation. However, studies for assessing the effectiveness of endodontic treatment of sealer based on Calcium Silicate have been not much.
- Trial name
- NCT05904184
- Testing
- Epoxy resin-based sealers (ERS), Calcium silicate-based sealers (CSS)
- Where
- Vietnam
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Chronic Musculoskeletal Pain, Veterans
Stepped-Care Intervention of Music and Imagery to Assess Relief (SCIMITAR) Trial
Th Stepped-Care Intervention of Music and Imagery to Assess Relief (SCIMITAR) Trial. SCIMITAR builds on our pilot study, the Feasibility and Acceptability of Music Imagery and Listening Interventions for Analgesia (FAMILIA)…
- Conditions
- Chronic Musculoskeletal Pain, Veterans, Music Therapy
- Trial name
- SCIMITAR (NCT07217821)
- Testing
- Stepped-care
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Knee Osteoarthritis
Deep Versus Superficial Heating in Patients With Knee Osteoarthritis
Heat therapy is frequently prescribed to patients with symptomatic knee osteoarthritis (OA). Deep hyperthermia via localized microwave diathermy is effective in several musculoskeletal painful conditions.
- Trial name
- NCT01343147
- Testing
- Microwave diathermy, Superficial hyperthermia
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Catholic University of the Sacred Heart
Orthopedic Disorder
r-ESWT in Moderate Knee Osteoarthritis
This study aims to compare the efficacy of r-ESWT treatment with sham-ESWT on pain, walking speed, physical function, and isokinetic muscle strength in knee osteoarthritis.
- Trial name
- NCT04243135
- Testing
- ESWT
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Mustafa Kemal University
Pain Management, Nursing Education
ChatGPT-Driven Blended Teaching for Pain Management in Nursing Students: A Randomized Controlled Trial
Pain management is a core competency in nursing practice, yet nursing students consistently demonstrate insufficient knowledge, unfavorable attitudes, limited competence, and low self-efficacy in this area.
- Conditions
- Pain Management, Nursing Education, Knowledge, Attitudes, Practice
- Trial name
- NCT07552363
- Testing
- ChatGPT-Driven Blended Teaching Model for Pain Management, Traditional Clinical Nursing Rounds
- Where
- Iran
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Alzheimer Disease
Clinical Analgesic Management in Dementia
This study is designed to assess the efficacy and safety of oxycodone in managing moderate to severe pain in patients with Alzheimer's disease.
- Trial name
- CALM-D (NCT07323914)
- Testing
- Tylex
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing
Back Pain
The Effect of PTH(1-84) or Alendronate on Reduction of Back Pain in Postmenopausal Women With an Osteoporosis Related Vertebral Fracture(s) (FP-005-IM)
The primary objective of this trial is to show that PTH(1-84) is superior to alendronate in reducing back pain intensity over a 24-week treatment period in postmenopausal women with an osteoporosis related vertebral fracture(s).
- Trial name
- NCT00713258
- Testing
- Parathyroid hormone (PTH) (1-84), Alendronate
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Nycomed
Liposomal Bupivacaine
Exparel Versus Bupivacaine in Post-operative Pain Control
This is a prospective, randomized study to evaluate anaesthetic parameters, postoperative analgesia and oral analgesic consumption comparing exparel (liposomal bupivacaine) vs. standard bupivacaine
- Trial name
- NCT06547255
- Testing
- Bupivacaine liposome injectable suspension
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Phacoemulsification
Clinical Analysis of Ocular Parameters Contributing to Intraoperative Pain During Standard Phacoemulsification
Charts of 142 patients who underwent standard phacoemulsification under topical anesthesia between March and August 2016 were reviewed.
- Trial name
- NCT03031652
- Testing
- Phacoemulsification
- Where
- South Korea
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Chronic Lower Limb Pain
A Safety and Effectiveness Trial of Spinal Cord Stimulation of the Dorsal Root Ganglion for Chronic Lower Limb Pain
The purpose of this study is to evaluate the safety and effectiveness of the AXIUM Neurostimulator System for the treatment of chronic lower limb pain in persons diagnosed with Complex Regional Pain Syndrome (CRPS) or Peripheral…
- Trial name
- ACCURATE (NCT01923285)
- Testing
- AXIUM Neurostimulator System, Control Spinal Cord Stimulation Device
- Where
- 22 sites in United States
- Volunteers
- 152 people
- Sponsor
- Abbott Medical Devices
Pain
Comparative Evaluation of Post-endodontic Pain Using Two Rotary Instrumentation Systems
In this study the investigators aim to compare the post-operative pain using two single-file endodontic rotary systems : Reciproc and One shape.
- Trial name
- NCT02621034
- Testing
- Control, Reciproc, One shape
- Where
- Iran
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences
Cataract, Anterior Chamber Inflammation
Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery
Phase 2b trial evaluating the safety and efficacy of EGP-437, versus placebo using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with implantation of a monofocal posterior chamber…
- Conditions
- Cataract, Anterior Chamber Inflammation, Pain, Postoperative
- Trial name
- NCT03180255
- Testing
- Dexamethasone phosphate
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Cervicogenic Headache
Effectiveness of a Novel Device for Cervical Training in Cervicogenic Headache.
The purpose of this study is to evaluate the clinical results in cervical spine range of motion, endurance deep cervical muscles, headache impact and physical activity enjoyment by a training protocol with the new device for…
- Trial name
- NCT05479149
- Testing
- Training protocol with the cervical device for treatment (CDAT)., Conventional training protocol
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Universitat Internacional de Catalunya
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