Clinical trials: Clinical Pain
Parkinson s Disease
Primary Parkinsonian Pain: Clinical Association and Phenotype
Among the different types of pain observed in Parkinson's disease, primary parkinsonian pain (PPP) is the most severe, the most difficult to treat, but also the least well characterized and the hardest to describe, not only by…
- Trial name
- PHENOPAIN (NCT07702266)
- Testing
- Online self-administered questionnaire
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Clermont-Ferrand
Low Back Pain
Comparison of Two Multidisciplinary Rehabilitation Interventions in Patients With Chronic Low Back Pain
Introduction Chronic low back pain (CLBP) is a highly prevalent health condition, and the leading cause of years lived with disability.
- Trial name
- NCT02884466
- Testing
- Multidisciplinary rehabilitation intervention
- Volunteers
- 165 people
- Sponsor
- Sano
Low Back Pain
Clinical and Neuromechanical Predictors for the Evolution of Chronic Non-specific Low Back Pain
The purpose of the present study is to determine the association between factors known to be associated with the development of chronic low back pain (psychological and biological) and the evolution of functional disability in…
- Trial name
- NCT02373345
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Université du Québec à Trois-Rivières
IUD Insertion Complication
Pain Relief During IUD Insertion in Women Delivered Only by Elective Cesarean Section
The aim of the work is to assess the effect of combined misoprostol 200 mcg and isosorbide mononitrate 40 mg versus misoprostol 200 mcg and placebo as local vaginal tablet on the successful IUD insertion.
- Trial name
- NCT03587077
- Testing
- Misoprostol, isosorbide mononitrate
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Assiut University
Injection Pain, Local Anesthesia Infiltration
Clinical Trial Comparing Pain Perception in Children Using Two Different Local Anesthesia Tools
The goal of this clinical study is to learn whether the Super Pen (SP) device can reduce pain during local anesthesia (LA) infiltration for primary teeth compared to the conventional syringe (CS) in children aged 6-12 years.
- Conditions
- Injection Pain, Local Anesthesia Infiltration, Pediatric Patient
- Trial name
- NCT07292194
- Testing
- super pen
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Lamis D. Rajab
Chronic Mechanical Neck Pain, Neck Pain
Targeted Cervical Versus Integrated Trunk and Diaphragmatic Muscle Retraining for Chronic Mechanical Neck Pain
Persistent pain, functional disability, cervical motor control deficit, and abnormal posture are associated with chronic mechanical neck pain.
- Trial name
- INT-CMNP (NCT07691151)
- Testing
- Integrated Physiotherapy, Conventional Physiotherapy
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Gulf Medical University
Myofacial Pain, Trigger Points, Myofascial
Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle
The goal of this randomized clinical trial is to compare the effectiveness of Botulinum toxin type A, magnesium sulfate and saline injections in treatment of the masseter muscle trigger points, in patients between 16 - 50 years…
- Trial name
- MPS MTrPs BTA (NCT06676475)
- Testing
- MgSO4, BOTOX-A
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Misr University for Science and Technology
Pain, Postoperative, Endodontically Treated Teeth
Postoperative Pain Intensity Associated With the Use of Different Nickel Titanium Instrumentation Systems
In this study the effect of different engine-driven nickel titanium (Ni-Ti) instrumentation systems (OneShape, Revo S and WaveOne) on postoperative dental pain in patients with asymptomatic teeth after a single-appointment root…
- Trial name
- NCT03478241
- Testing
- Group 1: single file rotary motion, Group 2: multiple file rotary motion, Group 3: single file reciprocal motion
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Nursing Caries, Emergencies
Venopuncture in Pediatric Emergency Department Using Koala's Distraction Method
A randomized clinical trial will be performed. Patients aged 3 and 4 years who attend the pediatric emergency service of the Miguel Servet Hospital in Zaragoza and require venipuncture will be selected.
- Conditions
- Nursing Caries, Emergencies, Venous Puncture
- Trial name
- NCT05453305
- Testing
- Control group: Traditional venipuncture, on the stretcher., Intervention group: DAK method venipuncture, simulating a hug
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Premenstrual Syndrome
Effects of Foot Bath Therapy on Premenstrual Syndrome Symptoms, Quality of Life, and Pain
The study was conducted as a randomized controlled trial to evaluate the effects of foot bath application on symptom severity, quality of life, and pain levels in women with premenstrual syndrome.
- Trial name
- NCT07461051
- Testing
- Foot bath therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Agri Ibrahim Cecen University
Labor Pain and Anxiety
Lavender and Lemongrass Aromatherapy for Pain and Anxiety in Labor: A Randomized Trial
Introduction: Pain experienced during labor is considered one of the main determinants of women's subjective experience throughout this physiological process.
- Trial name
- AROMA (NCT07522554)
- Testing
- Lavender and Lemongrass Aromatherapy
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Sao Paulo
To Determine the Onset of Analgesia (Numerical Rating Scale for Pain = 1) in Minutes
Comparison of Labor Analgesia Between Modified Combined Spinal-Epidural and Dural Puncture Epidural Techniques
Epidural, Combined Spinal-Epidural, and more recently dural puncture epidural are forms of neuraxial anesthesia used to provide pain relief in laboring women .
- Trial name
- NCT03258879
- Testing
- Modified CSE, Dural puncture epidural
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Pain
A Trial Comparing Different Dosing Regimens of Morphine in Patients With Moderate to Severe Pain
RESEARCH QUESTION: In adult ED patients in whom the attending ED physician has decided to administer intravenous opiates, what is the difference in pain relief at 60 minutes in patients who are randomized to receive either…
- Trial name
- NCT00293969
- Testing
- Morphine 0.1mg/kg versus morphine 0.15 mg/kg
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Montefiore Medical Center
Pain (Knee), Pain and Anxiety
A Comparison of Heart Rate Variability Biofeedback, Mindfulness, and Psychoeducation-based Interventions on Clinical Recovery Outcomes in Patients Undergoing Total Knee Arthroplasty
The goal of this clinical trial is to compare the effects of heart rate variability biofeedback (HRVB), mindfulness meditation, and psychological education in patients undergoing total knee arthroplasty (TKA).
- Conditions
- Pain (Knee), Pain and Anxiety, TKA
- Trial name
- NCT07896954
- Testing
- Heart rate variability biofeedback, Mindfulness, psychoeducation
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Angina Pectoris, Coronary Artery Disease
Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern
To investigate whether the use of Corus CAD (Age/Sex/Gene Expression score - ASGES) blood assay changes the diagnostic testing pattern in patients referred to a cardiologist for the evaluation of chest pain or anginal equivalent…
- Conditions
- Angina Pectoris, Coronary Artery Disease, Chest Pain, Cardiovascular Diseases
- Trial name
- IMPACT-CARD (NCT01251302)
- Testing
- Corus CAD (ASGES)
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- CardioDx
Low Back Pain
The Effect of Physical Therapy Program and Erector Spina Plane Block in Patients With Degenerative Lumbar Scoliosis
Degenerative (de novo) scoliosis is the result of a long and multifactorial process that occurs through degenerative change in the aging population without a pre-existing spinal deformity.
- Trial name
- NCT06018402
- Testing
- physical therapy, physical therapy + espb
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Molar, Third, Third Molar Surgery
3D Evaluation of Postoperative Edema After Third Molar Surgery
Surgical removal of third molars is recognized as one of the most frequent procedures performed in oral surgery. Literature is rich in studies attempting to demonstrate the benefit of corticosteroids in third molar surgery…
- Conditions
- Molar, Third, Third Molar Surgery, Soft Tissue Swelling, Pain, Postoperative
- Trial name
- NCT05941130
- Testing
- Combination of corticosteroid (methylprednisolone - Medrol, 16mg Pfizer Laboratories) therapy and non-steroidal anti-inflammatory (Ibuprofen 600mg Mylan) therapy, Non-steroidal anti-inflammatory therapy (Ibuprofen 600mg Mylan)
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Trapeziometacarpal Osteoarthritis, Thumb Osteoarthritis
ICF-Based Biopsychosocial Assessment With AI-Assisted Profile Prediction: Trapeziometacarpal Osteoarthritis Model
Trapeziometacarpal osteoarthritis (TMC OA) is a common condition affecting the base of the thumb that causes pain, weakness, and difficulty with daily hand use.
- Conditions
- Trapeziometacarpal Osteoarthritis, Thumb Osteoarthritis, Carpometacarpal Osteoarthritis, Thumb Basal Joint Osteoarthritis
- Trial name
- ICF (NCT07458971)
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Hacettepe University
Lumbar Disc Herniation
Clinical Research on the Efficacy of Thread-embedding Acupuncture on Herniated Intervertebral Disc of Lumbar Spine
This clinical trial is designed to evaluate the efficacy and safety of thread-embedding acupuncture for treatment of lumbar herniated intervertebral disc (L-HIVD) by assessing pain, function, and quality of life.
- Trial name
- NCT03236753
- Testing
- Thread-embedding Acupuncture (TEA)
- Where
- 4 sites in South Korea
- Volunteers
- 70 people
- Sponsor
- Kyunghee University Medical Center
Pain, Postoperative
Use of Oxycodone in Bariatric Surgery
There is still no effective treatment for surgical pain, especially visceral pain in bariatric surgery. Oxycodone has great application prospect in patients with obesity, but there are few clinical studies and analgesic effect is…
- Trial name
- NCT05515822
- Testing
- Oxycodone Hydrochloride, Dezocine, Esketamine and Oxycodone
- Volunteers
- 90 people
- Sponsor
- Qiang Fu
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