Clinical trials: Clinical Pain
Tennis Elbow, Lateral Epicondylitis
Leukocyte-Poor Platelet-Rich Plasma Reduces Pain Symptoms in the Treatment of the Lateral Epicondylitis
Lateral epicondylar tendinopathy (LET), or tennis elbow, is a degenerative condition affecting the forearm's extensor tendons. It commonly leads to pain, reduced grip strength, and impaired function, particularly in individuals…
- Conditions
- Tennis Elbow, Lateral Epicondylitis, Lateral Epicondylitis (tennis Elbow), PRP Injection
- Trial name
- LET (NCT06854666)
- Testing
- effectiveness of platelet-rich plasma (PRP) in treating lateral epicondylar tendinopathy (LET)
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Rehasport Clinic
Pain, Postoperative, Edema
Effectiveness of Light-emitting Diode (LED) Photobiomodulation in the Extraction of Retained Lower Third Molars
In dentistry, one of the most common surgical procedures is the removal of included third molars. This surgery generates great morbidity to patients for causing pain, edema and trismus due to surgical trauma.
- Conditions
- Pain, Postoperative, Edema, Trismus, Quality of Life
- Trial name
- NCT03442166
- Testing
- LED group
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Postoperative Pain
Regional Midazolam in Quadratus Lumborum Block
Midazolam has been used in regional anesthesia of brachial plexus block; it has offered accepted postoperative pain relief. This study will use it in as an adjuvant to bupivacaine 0.25% in quadratus lumborum block in caesarean…
- Trial name
- NCT05261672
- Testing
- Midazolam/ bupivaciane, Bupivacain
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Neck Pain, Kinesiophobia
Minimal Clinical Important Change of the Turkish Versions of the FABQ TKS, and PCS in Patients With Chronic Neck Pain
To investigate the reliability and sensitivity of the Fear-Avoidance Beliefs Questionnaire, Tampa Kinesiophobia Scale, and Pain Catastrophizing Scale in patients with chronic nonspecific neck pain undergoing multidisciplinary…
- Conditions
- Neck Pain, Kinesiophobia, Fear of Movement
- Trial name
- NCT06194812
- Testing
- Pain Catastrophizing scale
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Critical Illness, Pain
Pervasive Sensing and AI in Intelligent ICU
Important information related to the visual assessment of patients, such as facial expressions, head and extremity movements, posture, and mobility are captured sporadically by overburdened nurses, or are not captured at all.
- Conditions
- Critical Illness, Pain, Delirium, Confusion
- Trial name
- NCT05127265
- Testing
- Video Monitoring, Accelerometer Monitoring, Noise Level Monitoring
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Florida
Female Breast Cancer, Depression
An Intervention for Female Breast CANcer: Acceptance and Commitment Therapy (I-CAN-ACT) for Depression and Physical Pain
As a result of the cancer diagnosis and medical therapies, women with breast cancer often encounter debilitating cooccurring psychological and physical symptoms.
- Conditions
- Female Breast Cancer, Depression, Pain
- Trial name
- I-CAN-ACT (NCT05374161)
- Testing
- Acceptance and Commitment Therapy, Waitlist Control Group
- Where
- Cyprus
- Volunteers
- 88 people
- Sponsor
- University of Cyprus
Orthodontic Pain
Pain Control During Braces Removal Using Transcutaneous Electrical Nerve Stimulation and High-Frequency Vibration
This study aims to find the best method to reduce pain during braces removal. We are comparing transcutaneous electrical nerve stimulation (TENS), high-frequency vibration, and a control group with no additional intervention.
- Trial name
- NCT07293975
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), High-Frequency Vibration
- Where
- Iraq
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain, Cancer
Clinical Study of KW-2246 in Patients With Cancer Pain
This study is a Phase II open-label study to investigate the recommended conversion ratio (oral morphine dose to KW-2246) when switching oral morphine or oxycodone to KW-2246 in cancer patients.
- Trial name
- NCT00355628
- Testing
- KW-2246 (fentanyl citrate)
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Tooth Extraction, Local Anesthesia
Effect of AV Distraction and Acuapoint Stimulation in Pediatric Extraction on Pain and Anxiety
The aim of this study is to evaluate the effectiveness of audiovisual distraction and acuapoint stimulation on anxiety and pain perception during tooth extraction in children.
- Conditions
- Tooth Extraction, Local Anesthesia, Anxiety, Pain
- Trial name
- AV Acupoint (NCT07371442)
- Testing
- Acualief, Audiovisual, TELL SHOW DO
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Adenotonsillar Hypertrophy, Postoperative Pain
Conox-Guided Anesthesia in Pediatric Adenotonsillectomy
This study aims to evaluate the effect of Conox (qCON/qNOX)-guided anesthesia on intraoperative anesthetic drug consumption and postoperative outcomes in pediatric patients undergoing adenotonsillectomy.
- Trial name
- NCT07577154
- Testing
- Conox Monitor, Standard Anesthesia Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Kayseri City Hospital
Moderate Pain, Severe Pain
Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars
The purpose of this study is to evaluate the efficacy and safety of DIT112 in adolescents and adults with acute pain after dental surgery for the extraction of impacted third molars.
- Trial name
- ALIV (NCT06237231)
- Testing
- DIT112, DIPYRONE, TRAMADOL
- Volunteers
- 252 people
- Sponsor
- EMS
Fibromyalgia
Effect of a Functional Exercise Program Associated With Low Level Laser Therapy on Fibromyalgia
The purpose of this study is to investigate the effects of a functional exercise program associated with Low Level Laser Therapy (LLLT) on pain, functional capacity and quality of life of individuals with fibromyalgia.
- Trial name
- NCT03017339
- Testing
- Functional Exercise, Low Level Laser Therapy
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Computer-controlled Intraligamentary Anaesthesia, Inferior Alveolar Nerve Block
Comparison of the Computer Controlled and Conventional Local Anesthesia Techniques in Primary Molar Extraction in Children Aged 5 to 9 Years Old
The goal of this clinical trial is to assess pain perception, child stress level and compare the effectiveness between periodontal ligament anesthesia using Computer-controlled Local Anesthetic delivery system and the…
- Conditions
- Computer-controlled Intraligamentary Anaesthesia, Inferior Alveolar Nerve Block, Pain Perception, Anesthesia Effectiveness
- Trial name
- RCT (NCT06669039)
- Testing
- Computer-controlled Local Anesthetic delivery system, Inferior Alveolar Nerve Block
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Tooth Sensitivity
Diode Low-power Laser Before In-office Bleaching
Background: The aim of study was to investigate the effectiveness of low-level laser therapy (LLLT) use before in-office bleaching to prevent risk and intensity of tooth sensitivity.
- Trial name
- NCT05865275
- Testing
- Low-level laser treatment, tooth bleaching procedure
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Dental Pain
Technology-based Distraction Techniques in Managing Children With Attention-deficit/Hyperactivity Disorder
The present study aims to assess and compare the effectiveness of different technology-based distraction techniques on pain perception and dental anxiety in children with Attention Deficit/Hyperactivity Disorder during different…
- Trial name
- NCT07411157
- Testing
- Virtual reality glasses, White noise, Basic behavior management techniques
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Alexandria University
Pain
Efficacy of Neuromuscular Bandage Technique Against Jones Technique After the Supraespinatus Muscle Tendon Suture
The suture of the supraspinatus tendon is a common surgery that requires physical therapy for back pain and functional impairment to such surgery.
- Trial name
- NCT02812381
- Testing
- KT, SCS
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Multiple Rib Fractures, Pain, Acute
Ultrasound-guided Deep Versus Superficial Continuous Serratus Anterior Plane Block for Pain Management in Patients With Multiple Rib Fractures
The present clinical study will be undertaken to evaluate the effect of Ultrasound-guided Deep versus Superficial continuous Serratus Anterior Plane Block for pain management in patients with multiple rib fractures.
- Conditions
- Multiple Rib Fractures, Pain, Acute, Serratus Anterior Plane Block
- Trial name
- NCT04575272
- Testing
- Ultrasound-guided continuous serratus anterior plane block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Chronic Low Back Pain, Depression
Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression
This is a pilot study to evaluate the feasibility, acceptability, and safety of ketamine infusions followed by a brief behavioral intervention in Veterans with chronic low back pain and depression.
- Trial name
- NCT06419439
- Testing
- Ketamine hydrochloride, Minimally Enhanced Usual Care, Brief narrative intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Root Canal Infection
Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant
This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.
- Trial name
- NCT04250519
- Testing
- Sodium Hypochlorite
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tamil Nadu Dr.M.G.R.Medical University
Myofascial Pain - Dysfunction Syndrome of TMJ
Efficiency of Botulinum Toxin type-a in the Management of the Myofascial Pain
Study Title: Investigation of the Relationship Between Clinical Outcomes and Pain Mediators in the Treatment of Masticatory Muscle Disorders Associated with Myospasm Using Onabotulinum Toxin A Study Importance: Temporomandibular…
- Trial name
- NCT06840730
- Testing
- Botulinum Toxin A (Botox )
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Hacettepe University
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