Clinical trials: Clinical Pain
Irreversible Pulpitis (Toothache)
Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis
this clinical trial is evaluating the outcome of laser assisted pulpotomy compared to conventional pulpotomy in mature teeth with symptomatic irreversible pulpitis (SIP) assessed by CBCT followed by automated segmentation using…
- Trial name
- NCT07287709
- Testing
- Diode laser, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Rana Hegaz
Pelvic Pain Syndrome
Clinical Effect Observation for Electrical Pudendal Nerve Stimulation in Treating Urethral Pain Syndrome
In this randomized controlled trial, we intend to determine whether electrical pudendal nerve stimulation is more effective than intravesical instillation in urethral pain syndrome.
- Trial name
- NCT03671993
- Testing
- Electrical pudendal nerve stimulation, Intravesical instillation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Chronic Low-back Pain
Comparison of Swiss Versus Standard Low Back Acupuncture in Patients With Chronic Low Back Pain
Low back pain (LBP) is very common, widespread, and represents a multidimensional syndrome. It affects physical activity and function, health-related quality of life, and employment status.
- Trial name
- NCT05232487
- Testing
- Swiss low back acupuncture (SLBA), Standard acupuncture (SA)
- Where
- Switzerland
- Volunteers
- 116 people
- Sponsor
- Li Yiming
Postoperative Pain, Laparoscopic Hysterectomy for Benign Conditions
Randomized Clinical Trial: Effect of an Exercise Routine on Postoperative Shoulder Pain in Laparoscopic Hysterectomy
This is a clinical trial aimed at understanding the impact of a shoulder exercise routine on postoperative shoulder pain in patients who have undergone laparoscopic hysterectomy. Main Questions: 1.
- Trial name
- ERPOSP (NCT06195176)
- Testing
- Shoulder exercises, Hand exercises
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Acute Pain
Ketamine Versus Morphine Change Pain Profile
The aim of this study is to evaluate the efficacy of intravenous low dose ketamine infusion versus morphine infusion analgesia for pain reduction in Abdominoplasty surgery
- Trial name
- NCT03664622
- Testing
- Ketamine, Morphine
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Cairo University
Chronic Low-back Pain, Hip Impairments
Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain
Older adults with chronic low back pain (LBP) are at a greater risk for disability, loss of independence, and lower quality of life.
- Conditions
- Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
- Trial name
- MASH (NCT04009837)
- Testing
- Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Delaware
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214677
- Testing
- DW1809, DW1809-1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Acute Pain
Efficacy and Safety of Escócia Association in the Treatment of Acute Pain
The purpose of this study is to evaluate the efficacy and safety of Escócia association in adults with acute pain.
- Trial name
- NCT04666701
- Testing
- Escócia association, Ketorolac Tromethamine, Scopolamine
- Sponsor
- EMS
Hemorrhoidal Disease, Internal Hemorrhoids
Clinical Outcomes After Laser Hemorrhoidoplasty
This single-center prospective observational study aims to evaluate clinical outcomes, postoperative pain scores, complications, and patient satisfaction in adults undergoing laser hemorrhoidoplasty for symptomatic internal…
- Trial name
- LHP (NCT07520734)
- Testing
- Laser Hemorrhoidoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Clinical Comparison of Patellofemoral Pain Syndrome Outcomes After Blood Flow Restriction Therapy
The purpose of this study is to determine if Blood Flow Restriction therapy improves patient related outcomes in those diagnosed with Patellofemoral Pain Syndrome compared to those in the sham comparator control group.
- Trial name
- NCT05617911
- Testing
- Blood Flow Restriction Cuff
- Where
- 6 sites in United States
- Volunteers
- 1 people
- Sponsor
- Gaylord Hospital, Inc
Impacted Third Molar Tooth, PAIN
An Randomized Control Trial Comparing Two Drug Combinations for Pain Management After Third Molars Surgery
Randomised control clinical trial to compare which combination of analgesics in effective in pain management after third molar extraction of wisdom teeth.
- Trial name
- NCT04874675
- Testing
- diclofenac / acetaminophen /codeine, ibuprofen/acetaminophen/codeine
- Where
- Zimbabwe
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Oral Pain, Oral Pungent Sensation
Efficacy of Oral HA35 for Rapid Relief of Oral Pain and Pungent Sensation
This prospective, open-label, controlled pilot study evaluates oral 10% 35 kDa hyaluronan (HA35) versus four control interventions (C60 grapeseed oil，normal saline) for relief of capsaicin/AITC-induced oral pain and pungent…
- Conditions
- Oral Pain, Oral Pungent Sensation, Capsaicin-Induced Pain, AITC-Induced Irritation
- Trial name
- NCT07630571
- Testing
- Capsaicin Oral Challenge, Allyl Isothiocyanate (AITC) Oral Challenge, 10% 35 kDa Hyaluronan (HA35) Oral Solution
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nakhia Impex LLC
Low Back Pain, Nutrition Poor
Nutrient Nutritional Advise for Low Back Pain Patients Seeking Chiropractic Care
The nutritional intervention will reduce LBP and cause 10% weight loss.
- Trial name
- NCT04134013
- Testing
- Combination: Nutrition AND Chiropractic Adjustment, Chiropractic Adjustment: Spinal Manipulation Therapy
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Parker University
Acute Pain Due to Trauma
Methoxyflurane vs Standard Analgesic Treatment for Trauma Pain in Spanish Emergency Units
Clinical trial to compare pain relief between methoxyflurane and any analgesic treatment used in usual clinical practice, in patients with trauma and associated pain, treated in Spanish emergency units.
- Trial name
- InMEDIATE (NCT03256903)
- Testing
- Methoxyflurane, Standard of care
- Where
- 14 sites in Spain
- Volunteers
- 310 people
- Sponsor
- Mundipharma Pharmaceuticals S.L.
Nonspecific Low Back Pain
Effects of Muscle Energy Technique and Pilates Exercises on Pain and Physical Function in Patients With Nonspecific Low Back Pain
This randomized clinical trial aimed to compare the effects of Muscle Energy Techniques (METs) and Pilates exercises on pain and physical function in individuals with nonspecific low back pain.
- Trial name
- NCT07458776
- Testing
- Muscle Energy Technique, Pilates Exercises
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Chronic Low-back Pain (cLBP)
Effects of Myofascial Techniques on Chronic Low Back Pain
Participants with chronic low back pain will be randomly allocated to three groups: conservative treatment, conservative treatment plus local myofascial release, or conservative treatment plus superficial back line myofascial…
- Trial name
- NCT07915817
- Testing
- Local Myofascial Release, Superficial Back Line Myofascial Release, Conservative treatment
- Volunteers
- 60 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury
High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury
Traumatic peripheral nerve injury is a common cause of chronic neuropathic pain, muscle weakness, and functional limitation, particularly in young and active individuals.
- Conditions
- Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury, Neuropathic Pain, Peripheral Nerve Injuries, Traumatic
- Trial name
- NCT07705490
- Testing
- High-Intensity Peripheral Magnetic Stimulation, Therapeutic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Osteoarthritis, Knee, Postoperative Pain
A Randomized Comparison of the Efficacy of the IPACK Block Versus the Popliteal Plexus Block for Posterior Knee Analgesia, in Patients Undergoing a Total Knee Arthroplasty and Receiving a Continuous Distal Femoral Triangle Block
Total knee arthroplasty (TKA) is commonly associated with significant postoperative pain, including pain arising from the posterior aspect of the knee.
- Trial name
- NCT07876310
- Testing
- Ultrasound-Guided iPACK Block, Ultrasound-Guided Popliteal Plexus Block, Ultrasound-Guided Continuous Femoral Triangle Block
- Volunteers
- 136 people
- Sponsor
- Clinica Santa Maria
Chronic, Intractable Back Pain and/or Leg Pain
Clinical Trial of MED HF10™ Spinal Cord Stimulation for the Treatment of Chronic Pain
This is a single-center, prospective, non-randomized exploratory study in subjects with chronic, intractable back pain and/or leg pain per the center's routine practice.
- Trial name
- MED (NCT06897280)
- Testing
- SCS Device Program Setting
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nevro Corp
Nephrectomy
Dexmedetomidine Versus Fentanyl as Adjuvants to Erector Spinae Plane Block for Postoperative Analgesia Following Simple Nephrectomy: A Randomized Clinical Trial
The aim of this clinical trial is to compare the time to first analgesic request between dexmedetomidine and fentanyl as adjuvants in erector spinae plane block in patients undergoing simple nephrectomy .
- Trial name
- DEX/Fentanyl (NCT06799442)
- Testing
- Erector Spinae Plane Block, Dexmedetomidine, fentanyl
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Assiut University
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