Clinical trials: Clinical Pain
Knee Osteoarthritis
The Effectiveness of Kinesio Taping Method for Knee Osteoarthritis.
Purpose of our study is to evaluate effectiveness of Kinesio Taping method for knee osteoarthritis. Using simple concealed randomization procedure to form two groups (kinesio taping and control-nonspecific taping) of 100 knee…
- Trial name
- NCT03076177
- Testing
- Taping application
- Where
- Lithuania
- Volunteers
- 187 people
- Sponsor
- Lithuanian University of Health Sciences
Periodontitis
Effect of Periodontitis Treatment on Quality of Life and Experiences of Fear, Anxiety and Pain
There are different protocols to treat gum diseases. One relevant differential aspect is related to time. There are protocols that usually takes one to two months to be completed while other are completed within 24 hours.
- Trial name
- NCT02409966
- Testing
- Quadrant-wise scaling, Full-mouth 24-hour scaling
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Osteoarthritis of the Knee
Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis
The study will identify the efficacy of Apitox, purified honeybee toxin, in 330 patients with diagnosed osteoarthritis of the knee.
- Trial name
- NCT01112722
- Testing
- Apitox, purified honeybee toxin, lyophilized in saline, histamine
- Where
- 15 sites in United States
- Volunteers
- 363 people
- Sponsor
- Apimeds, Inc.
Pain, Postoperative, Periapical; Infection
Clinical and Radiographic Evaluation of Zinc Oxide-Propolis Mixture Versus Modified Triple Antibiotic Paste in LSTR
The aim of this study is to evaluate and compare the clinical effectiveness of zinc oxide-propolis mixture with triple antibiotic paste in LSTR as root canal filling material in necrotic primary molars.
- Trial name
- NCT06158451
- Testing
- Zinc oxide propolis, Modified triple antibiotic paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-operative Pain, Acute, Opioid Use, Unspecified
Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care
The goal of this clinical trial is to learn if the Pain Coach App will result in less opioids being prescribed to and used by patients undergoing Shoulder/Hip/Knee Arthroplasty surgery while maintaining the same or better pain…
- Conditions
- Post-operative Pain, Acute, Opioid Use, Unspecified, Arthroplasty Complications, Knee Osteoarthritis
- Trial name
- NCT06469177
- Testing
- Pain Coach App
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Oral Mucositis, Oral Stomatitis
Ozone Therapy for Oral Mucositis in Patients Receiving Head and Neck Cancer Radio- and Chemotherapy
Oral mucositis is a frequent and painful side effect of radio- and chemotherapy, especially in patients with head and neck cancer.
- Conditions
- Oral Mucositis, Oral Stomatitis, Head and Neck Cancer Squamous Cell Carcinoma, Radiotherapy Induced Mucositis
- Trial name
- OZOMUC (NCT07199712)
- Testing
- Ozone Therapy (In-Office and Home-Based Treatment)
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- University of Pavia
Aging, Stroke
Precision Vibration Therapy for Neuromuscular and Functional Improvement in Older Adults and Stroke Survivors
To address muscle weakness, sensory degradation, functional decline, and pain caused by geriatric syndromes in older adults and stroke survivors, this project proposes a series of studies aimed at improving neuromuscular…
- Trial name
- NCT07351877
- Testing
- Precision Vibration Therapy, Conventional Rehabilitation
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Health Research Institutes, Taiwan
Pain, Myofascial Pain Syndrome
Efficacy of Kinesiology Tape on Neck Disability
Sixty participants with nonspecific neck pain were randomly assigned to either the kinesiotaping (n=30) or exercise (n=30) group.
- Conditions
- Pain, Myofascial Pain Syndrome, Trigger Point Pain, Myofascial
- Trial name
- NCT05030181
- Testing
- kinesiotaping and exercise, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Symptomatic Irreversible Pulpitis, Postoperative Pain
Effect of Preoperative Video-Guided Breathing on Pain in Symptomatic Irreversible Pulpitis
The goal of this randomized controlled clinical trial is to evaluate whether a brief preoperative video-guided breathing exercise reduces postoperative pain in adults undergoing single-visit root canal treatment for symptomatic…
- Trial name
- NCT07859267
- Testing
- Video-Guided Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cukurova University
Chronic Pain
Clinical Evaluation of the EpiFaith™ Syringe in Epidural Pain Management
This study evaluates a new medical device called the EpiFaith™ Syringe, which is designed to help clinicians more accurately identify the epidural space during pain management procedures.
- Trial name
- NCT07654907
- Testing
- EpiFaith™ Syringe, Conventional Loss-of-Resistance Syringe
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Flat Medical Co., Ltd
Osteo Arthritis Knee, Pain, Postoperative
Comparing Single Dose and Multiple Dose of Dexamethasone Post TKA
The goal of this clinical trial is to investigate the efficacy of single dose and double dose of dexamethasone after primary total knee replacement.
- Trial name
- NCT06339151
- Testing
- Dexamethasone before surgery, Dexamethasone before and 12 hours after surgery, Dexamethasone before and 24 hours after surgery
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Thammasat University Hospital
Pain, Acute
Impact of Virtual Reality in Cardiac Electrophysiology
Pain during pacemaker or defibrillator implantation can increase patient discomfort, anxiety, and the need for deeper sedation. Using virtual reality (VR) as a non-pharmacological distraction tool may help reduce perceived pain…
- Trial name
- NCT07009951
- Testing
- Virtual reality
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Calabria
Low Back Pain
Electroacupuncture Frequency-related Effects on Non-specific Low Back Pain in Older Adults.
Background: Low back pain (LBP) is the most frequent complaint in the clinical practice. Electroacupuncture treatment may be effective, however, the evidence supporting this possibility is still limited, especially in older…
- Trial name
- NCT03802045
- Testing
- Electroacupuncture, Needle, Adhesive Moxa
- Where
- 2 sites in Brazil
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Chronic Low Back Pain
Manual Therapy Plus Capacitive and Resistive Electric Transfer Therapy in Individuals With Chronic Low Back Pain
Chronic low back pain is defined as back pain that lasts longer than 12 weeks. The aim of this clinical study is to investigate the efficacy of combining a program of manual techniques with the application of Capacitive and…
- Trial name
- NCT05680467
- Testing
- Manual Therapy, Manual Therapy plus TECAR, Control
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- International Hellenic University
Frozen Shoulder
3-Dimensional Shoulder Complex Pain Alignment (3-D SPA) Mobilization on Frozen Shoulder.
Ongoing research aims to assess the enhancement of shoulder mobility by specifically addressing restrictions in all three planes of movement.
- Trial name
- NCT06530602
- Testing
- 3 D SPA (shoulder complex pain alignment) Moblization, Shoulder Moblization (KaltenBorn)
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Angina
Optical Coherence Tomography to Improve Clinical Outcomes During Coronary Angioplasty
Coronary artery stenting has evolved as an effective treatment for angina and involves stretching up narrowings within the heart arteries using a balloon (coronary angioplasty) before implanting a small metal scaffold (stent) to…
- Trial name
- NCT02065102
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Royal Infirmary of Edinburgh
Peripheral Nerve Injury, Postherpetic Neuralgia
Study of Capsaicin Patch for the Management of Peripheral Neuropathic Pain
The efficacy and safety of the low concentration [0.65% (50 µg/cm2) and 1.25% (100 µg/cm2)] capsaicin patches and compared them to conventional 0.075% capsaicin cream and placebo patch in patients suffering from peripheral…
- Trial name
- NCT02228928
- Testing
- CAPNP, 50 ug/cm2 capsaicin patch, CAPNP, 100 ug/cm2 capsaicin patch, 0.075% capsaicin cream
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Chronic Pain
Effect and Safety of Listening to Music for Chronic Pain Relief
Chronic pain is a multidimensional pathological condition that reduces patients' quality of life and interferes with their daily family and work activities. Opioids are the most powerful analgesics in the treatment of pain.
- Trial name
- NCT05726266
- Testing
- Music, Audiobook
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Víctor Fernández-Dueñas
Pediatric Postoperative Pain
Postoperative Pain After Pediatric Umbilical Hernia Repair
The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia…
- Trial name
- NCT01015053
- Testing
- bilateral ultrasound-guided rectus sheath block, Wound infiltration
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Pain, Complications
Comparison of Three Kinds of Postoperative Analgesia After Total Knee Arthroplasty
Postoperative pain after total knee arthroplasty (TKA) can be difficult to manage and may delay recovery. There are multimodal postoperative pain management after TKA, including intravenous opioids, epidural analgesia, peripheral…
- Trial name
- NCT02094339
- Testing
- Local analgesic, Nerve Block, Intravenous analgesic
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
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