Clinical trials: Clinical Practice
HIV
Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women
This study will inform international medical guidelines as to whether the Levonorgestrel intrauterine device (LNG IUD), a highly effective long-acting reversible contraceptive method, is safe and acceptable as compared to the…
- Trial name
- NCT01721798
- Testing
- Mirena levonorgestrel IUD, Copper T-380a IUD
- Where
- South Africa
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- FHI 360
Orthodontic, Interproximal Enamel Reduction
Pain Associated With Interproximal Enamel Reduction in Orthodontics: a RCT
Prospective randomised crossover trial to assess if there is a difference in the level of pain experienced by orthodontic patients undergoing interpromixal enamel reduction at the lower incisor region using either a motor driven…
- Trial name
- IER (NCT02455700)
- Testing
- Interproximal Enamel Reduction
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Female Sexual Dysfunction (FSD), Sexuality and Reproductive Issues
Developing a Clinical Practice Guideline With The Delphi Technique for Evaluation and Counseling of Women's Sexual Health
Type of Research The research will be conducted prospectively and methodologically. The Delphi Technique, one of the qualitative research methods, will be used.
- Trial name
- NCT06880900
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Clinical Practice, Virtual Reality
The Effect of the Operating Room Environment on Patients Experienced With Virtual Reality Glasses Before Surgery
This study was planned as a randomized controlled experimental study with a pretest-posttest design to examine the effect of the operating room environment experience of preoperative patients using virtual reality glasses on the…
- Conditions
- Clinical Practice, Virtual Reality, Nursing Care, Simulation
- Trial name
- NCT06666465
- Testing
- Operating Room Environment Experienced by Patients Wearing Virtual Reality Glasses Before Surgery The Effect of Surgery Experience on Surgical Fear Level and Care Perceptions
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Kidney Disease, End-Stage
Electronic Patient-Reported Outcomes in Clinical Kidney Practice (ePRO Kidney)
People living with end-stage kidney disease (ESKD) need dialysis or transplantation in order to stay alive. This illness and treatment significantly impact peoples' health, emotions, work and relationships.
- Trial name
- NCT03149328
- Testing
- Educational Support
- Where
- 2 sites in Canada
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Eating Disorders in Adolescence
Social Information Processing in Adolescents With Eating Disorders
This research project aims to examine whether adding an online programme of cognitive training exercises may be a helpful addition to treatment as usual for young people with eating disorders.
- Trial name
- NCT03563755
- Testing
- Cognitive Bias Modification
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- King's College London
Vulva Cancer, Nurse Role
Simulation Supported Vulva Cancer and Self-Examination on Knowledge, Skills and Attitude
Objective: The aim of this study was to examine the effect of simulation-assisted vulvar cancer and vulva self-examination training on knowledge, skills and attitudes towards clinical practices.
- Trial name
- NCT07159958
- Testing
- Simulation-Based Vulvar Cancer and Self-Vulvar Examination Training
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Trakya University
Alzheimer Disease, Mild Cognitive Impairment
Enriching Clinical Trials Requiring Amyloid Positivity With Practice Effects
The primary objective of this study is to demonstrate that individuals with low short-term practice effects (STPE) on cognitive testing are more likely to be identified as "positive" on amyloid imaging than individuals with high…
- Trial name
- APPE (NCT03466736)
- Testing
- [18F]flutemetamol PET scan
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Utah
Child, Only
Effect of Classic Ballet Practice on School Children's Postural Balance
Is a parallel longitudinal protocol where half patients receive a experimental protocol and the other half receive orientation to maintain your daily live routine as usually. The experimental protocol include Ballet sessions.
- Trial name
- NCT03629821
- Testing
- Ballet
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Decision Making, Chromosome Abnormality
Efficacy of Counseling for Prenatal Screening and Diagnostic Tests on Pregnant Women: Randomised Controlled Study
The aim of this study was to evaluate the effect of counseling for prenatal screening and diagnostic tests on pregnant women's decisional conflict, being sure of the decision, anxiety levels, and attitudes towards the tests.
- Conditions
- Decision Making, Chromosome Abnormality, Anxiety, Knowledge, Attitudes, Practice
- Trial name
- NCT03825978
- Testing
- Prenatal Genetic Counseling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Stroke
TCM Clinical Practice Rehabilitation of Post-stroke Spasticity
The purpose of this study is to determine the effectiveness,safety and Input-output ratio of chinese traditional treatment in spasm after stroke,both in massage and herbal medicine bathing.
- Trial name
- NCT03054974
- Testing
- Modern rehabilitation treatment, Modern rehabilitation &TCM, modern rehabilitation &Baimai Ruangao
- Where
- China
- Volunteers
- 1,208 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Contraception
Long-Acting Reversible Contraception
In the proposed study, women aged 18-29 seeking oral or injectable contraception will be offered an opportunity to try LARC instead; the FDA-approved options include two types of intrauterine products and one type of subdermal…
- Trial name
- LARC (NCT01299116)
- Testing
- DMPA, oral contraceptives, Implanon®
- Where
- United States
- Volunteers
- 916 people, healthy volunteers welcome
- Sponsor
- FHI 360
Pit-and-Fissure Sealants
An Implementation Strategy for the Adoption of an Evidence-Based Guideline for Pit-and-Fissure Sealants
The purpose of this implementation science study is to determine whether Deliberative Loops are effective in increasing providers' adherence to the non-cavitated caries component of the American Dental Association's…
- Trial name
- DISGO (NCT04682730)
- Testing
- Deliberative Loop
- Where
- United States
- Volunteers
- 896 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Skin Cancer
Implementation of Teledermoscopy and Artificial Intelligence
The study has 2 parts. Part 1 will investigate the effects of introducing teledermoscopy in clinical practice, more specifically the change in referral patterns, the risk of undetected skin cancers and the effect on diagnostic…
- Trial name
- NCT05033678
- Testing
- Diagnostic algorithms
- Where
- Sweden
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Region Skane
Delivery Outcomes
Interdisciplinary Practice Bundle for Second-Stage of Labor and Clinical Outcomes
This study aims to assess the effect of implementing an interdisciplinary practice bundle during second-stage of labor on clinical outcomes.
- Trial name
- NCT07055490
- Testing
- Interdisciplinary Practice Bundle
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Contraception
Acceptability of Depo-subQ in Uniject
This is an observational study to assess the experience of current depot medroxyprogesterone acetate (DMPA) intramuscular (IM) clients and providers when they try Depo-subQ in Uniject and offer recommendations for the…
- Trial name
- NCT01667276
- Where
- 2 sites in Senegal, Uganda
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- FHI 360
Manual Dexterity, Self-Confidence
The Impact of Virtual Reality Haptic Simulators and Mobile Apps in Endodontic Clinical Practice
Endodontics presents unique challenges due to the complexity and precision required in procedures such as access cavity preparation, canal instrumentation, and obturation.
- Conditions
- Manual Dexterity, Self-Confidence, Stress Level
- Trial name
- NCT07097233
- Testing
- Virtual Reality Haptic Simulator, Mobile app, Control
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Skin Aging
A Clinical Study to Evaluate the Efficacy and Satisfaction of Ultrasound Therapy Combined With SkinCeuticals A.G.E for Improving Facial Aging
A Prospective, Single-center, Single-blind, Randomized split-face, controlled trial will be conducted. The goal of this clinical trial is to evaluate the efficacy and satisfaction of ultrasound therapy combined with SkinCeuticals…
- Trial name
- NCT05748470
- Testing
- SkinCeuticals A.G.E, standard cream
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yes Skin Medical Group
Cognitive Decline, Cognitive Dysfunction
Open-label, Post-marketing, Prospective Study to Assess Impact of COVID-19 on Cognitive Function in Patients
The objective of this study is to compare the impact of the coronavirus disease (SARS-CoV-2, or COVID-19) on cognitive function in the population of patients who have been diagnosed, treated and recovered from the COVID-19…
- Conditions
- Cognitive Decline, Cognitive Dysfunction, Brain Health, Post CoV-2 Syndrome
- Trial name
- COVID19 (NCT04950673)
- Testing
- Cognivue
- Where
- 4 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cognivue, Inc.