Clinical trials: Clozapine Resistant Schizophrenia
Treatment Resistant Schizophrenia, Clozapine Adverse Reaction
Effect of Atenolol Versus Ivabradine on HRV in TRS Patients on Clozapine With Tachycardia: A Randomised Control Trial.
Clozapine is the only drug approved for Treatment Resistant Schizophrenia. However, it has been associated with many adverse drug reactions including agranulocytosis, myocarditis, sialorrhea, constipation, orthostasis…
- Conditions
- Treatment Resistant Schizophrenia, Clozapine Adverse Reaction, Heart Rate Variability, Tachycardia
- Trial name
- NCT06505668
- Testing
- Atenolol 25 mg, Ivabradine 10mg
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Schizophrenia, Schizophrenic Disorders
Clozapine/Paliperidone Versus Clozapine/Placebo in Resistant Schizophrenia
augmentation of clozapine with paliperidone in the treatment of resistant schizophrenia has not been tested until now in randomized controlled trials.
- Conditions
- Schizophrenia, Schizophrenic Disorders, Psychotic Disorder
- Trial name
- NCT01279213
- Testing
- paliperidone clozapine
- Where
- Argentina
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Rosario
Schizophrenia
Ziprasidone for Clozapine- or Olanzapine-Associated Diabetes Mellitus
This study is a six-week, open label trial of the novel antipsychotic agent, ziprasidone, added to a stable dose of clozapine or olanzapine in 40 diabetes mellitus patients, patients with an impaired fasting glucose or insulin…
- Trial name
- NCT00351000
- Testing
- Ziprasidone
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- North Suffolk Mental Health Association
Schizophrenia
Response to Clozapine in Treatment Resistant Schizophrenia: A Longitudinal Magnetic Resonance Spectroscopy Study
The purpose of this study is to investigate the relationship between glutamate and related brain chemicals and treatment response to clozapine in patients with treatment-resistant schizophrenia.
- Trial name
- NCT02714894
- Testing
- Clozapine
- Where
- Canada
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health