Clinical trials: Cluster Headache
Cluster Headache
Cluster Headache Treatment With Rimegepant
The purpose of this research is to explore the efficacy of rimegepant as a preventative therapy for cluster headache.
- Trial name
- NCT05264714
- Testing
- Rimegepant
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Refractory Chronic Cluster Headache
Refractory Chronic Cluster Headache: Exploring the Potential of Repetitive Transcranial Magnetic Stimulation
The goal of this clinical trial is to learn if drug ABC works to treat severe asthma in adults. It will also learn about the safety of drug ABC.
- Trial name
- NCT06917144
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Hospital Universitario La Paz
Migraine Headaches, Breathing Techniques
Effect of Breathing Techniques on Migraine Attacks and Severity
Background: Migraine is a very common neurobiological disorder caused by increased excitability of the Central Nervous System. It is among the causes of the highest morbidity worldwide.
- Trial name
- NCT05536635
- Testing
- breathing techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Dokuz Eylul University
Primary Headache, Migraine in Adolescence
nVNS for the Prevention and Treatment of Primary Headache
This study is a single-center, single-arm study. All subjects will receive the same treatment. Children and adolescents (7-20 years old) with migraine who met the inclusion criteria will be enrolled as subjects in the…
- Conditions
- Primary Headache, Migraine in Adolescence, Migraine in Children, Cluster Headache
- Trial name
- NCT06277063
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Fibromyalgia, Chronic Migraine, Headache
Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and Vulvodynia
Chronic pain (CP) is a substantial healthcare challenge with considerable economic costs. Recently, the term Nociplastic Pain (NP) has been introduced as a third descriptor of mechanisms related to CP.
- Conditions
- Fibromyalgia, Chronic Migraine, Headache, Vulvodynia
- Trial name
- PSYCHOFIBRO (NCT06138171)
- Testing
- Psychological self-reported measures assesment (questionnaire)
- Where
- Italy
- Volunteers
- 1,006 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Episodic Cluster Headache
R-Verapamil for the Prophylaxis of Episodic Cluster Headache
This is a double-blinded, randomized, parallel, placebo-controlled phase 2 study to evaluate the safety and efficacy of R-verapamil in the prophylaxis of episodic cluster headache.
- Trial name
- NCT02209155
- Testing
- R-verapamil 75 mg tablet
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Center Laboratories, Inc.
Chronic Cluster Headache
Cephalic Vascular Recording Upon SPG Stimulation
Hypothesis: Stimulation of the SPG at high frequencies (50-200Hz) is believed to cause a physiological parasympathetic block which decreases VMCA oxyHb concentration and cephalic vessel diameter.
- Trial name
- NCT01359631
- Volunteers
- 7 people
- Sponsor
- Autonomic Technologies, Inc.
Cluster Headache Attacks
Administration of Oxygen to Cluster Headache Patients
This study will investigate the possible difference in treatment effect between three different oxygen delivery systems in the acute treatment of cluster headaches.
- Trial name
- NCT01589588
- Testing
- Open Hudson Mask, Cluster headache mask with 3 L reservoir, Mask 3
- Where
- Denmark
- Volunteers
- 57 people
- Sponsor
- Mads Barløse
Primary Headaches (Migraines, Tension, Cluster Headaches)
Osteopathic Manual Therapy (OMT) and Brain Structure and Function in Primary Headache Patients: A Pilot Study
Chronic headaches are associated with changes in brain structure and function that may be associated with increased suffering and disability.
- Trial name
- NCT06841627
- Testing
- Osteopathic Manipulative Therapy
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Headache Disorders
Occipital Nerve Stimulation to Treat Chronic Headaches
The purpose of this study is to evaluate the safety and efficacy of a implantable device, called the bion(R), in the treatment of chronic headache.
- Trial name
- NCT00205894
- Testing
- bion microstimulator
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Boston Scientific Corporation
Primary Headache
Two US-guided Techniques for Greater Occipital Nerve Blocks
Headache is one of the most common reasons for patients to access healthcare. Greater occipital nerve (GON) block with local anesthetic and steroid has been described for the management of primary headache refractory to…
- Trial name
- GON (NCT02031822)
- Testing
- US-guided Greater Occipital Nerve Injection
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Cluster Headache
The Efficacy and Safety of Sphenopalatine Ganglion Pulsed Radiofrequency Treatment for Cluster Headache
The investigators aim to investigate the effectiveness and safety of sphenopalatine ganglion pulsed radiofrequency on cluster headache.
- Trial name
- NCT03567590
- Testing
- Pulsed Radiofrequency treatment, Nerve Block treatment
- Where
- 3 sites in China
- Volunteers
- 80 people
- Sponsor
- Beijing Tiantan Hospital
Episodic Cluster Headache
Intranasal Civamide for Episodic Cluster Headache
This is a 49-day study to evaluate the effectiveness of Intranasal Civamide (Zucapsaicin) in the treatment of an episodic cluster headache period compared to placebo (medically inactive substance which does not contain any active…
- Trial name
- NCT00069082
- Testing
- Civamide (Zucapsaicin), Sodium Chloride
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- Winston Laboratories
Cluster Headache
Evaluation of Efficacity and Safety of Deep Brain Stimulation (DBS) in Chronic and Treatment-Resistant Cluster Headache(CH)
The aim of this study is to evaluate the efficacy and safety of deep brain stimulation (DBS) in chronic and treatment-resistant CH.
- Trial name
- NCT00662935
- Testing
- setting-up of an electrode in deep brain
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Migraine, Cluster Headache
Intranasal Cooling for Cluster Headache and Migraine
This study will be looking at the clinical efficacy of using a intranasal evaporative cooling device in providing relief of the symptoms of migraine and cluster headache.
- Trial name
- COOLHEAD (NCT01898455)
- Testing
- RhinoChill intranasal cooling
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Cumbria Partnership NHS Foundation Trust
Chronic Cluster Headache
A Study Comparing the Efficacy and Safety of Fremanezumab (TEV-48125) for the Prevention of Chronic Cluster Headache (CCH)
The purpose of the current study is to evaluate the efficacy and safety of Fremanezumab (TEV-48125), in the prevention of CCH in adult participants.
- Trial name
- NCT02964338
- Testing
- Fremanezumab
- Where
- 83 sites in United States, Australia and 10 more
- Volunteers
- 259 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Cluster Headache
High Dose Vitamin D Plus Multivitamin in the Prevention of Cluster Headache
This study intends to investigate the use of high-dose Vitamin D3 plus a multivitamin in the prevention of cluster headache attacks.
- Trial name
- NCT04570475
- Testing
- Vitamin D, multivitamin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cluster Headache
Double-Blind Comparison of the Efficacy and Safety of C213 to Placebo for the Acute Treatment of Cluster Headaches
This is a double-blind, placebo-controlled study. Subjects who meet the entry criteria will be randomized o receive one of three blinded treatments [C213 1.9 mg patch and placebo patch; C213 3.8 mg (1.9 mg x 2 patches), two…
- Trial name
- NCT04066023
- Testing
- C213 Microneedle System
- Where
- 12 sites in United States
- Volunteers
- 42 people
- Sponsor
- Zosano Pharma Corporation
Cluster Headache
Sodium Oxybate in Patients With Episodic and Chronic Cluster Headache
The purpose of this study is to test the effects of sodium oxybate on headache response (frequency), sleep quality and quality of life in the prophylactic treatment of patients with chronic and episodic cluster headache.
- Trial name
- SOinCH (NCT02637648)
- Testing
- Sodium Oxybate
- Volunteers
- 60 people
- Sponsor
- Ramin Khatami
Chronic Cluster Headache
Sphenopalatine Ganglion Stimulation for the Treatment of Chronic Cluster Headache
The primary objective of the study is to demonstrate the safety and efficacy of SPG stimulation with the ATI Neurostimulation System when used to treat acute cluster attacks in chronic cluster headache patients.
- Trial name
- NCT02168764
- Testing
- ATI Neurostimulation System
- Where
- 24 sites in United States
- Volunteers
- 120 people
- Sponsor
- Autonomic Technologies, Inc.