Clinical trials: Cochlear Function Disorder
Deafness
Restauration of the Auditory and Cognitive Functions in Cochlear Implanted Deaf Children in fNIRS
The principal aim of this study is to evaluate the cortical developement of perceptual skills and executive functions over time, in children with cochlear implants aged 10-24 months and 3-7 years compared with normally hearing…
- Trial name
- HearCog (NCT04495660)
- Testing
- Near InfraRed Spectroscopy (fNIRS), Passive perceptual stimulation, Task A not B
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Toulouse
Hearing Loss
Use of Functional Near-infrared Spectroscopy to Investigate Role of Human Auditory Cortex Plasticity and Multi-sensory Integration on Cochlear Implant Performance After Single-sided Deafness
The timing of brain changes that may influence hearing rehabilitation within human A1 after single-sided deafness (SSD) is not known. The goal is to determine when A1 neural plasticity occurs following SSD onset.
- Trial name
- NCT03713554
- Testing
- FNIRS Observational
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Hearing Loss, Cochlear Implant
AB-Intra- and Post-Operative Measures of Auditory Function
The purpose of this study is to see how the inner ear responds to sound delivered to the ear canal during and after your cochlear implant surgery.
- Trial name
- AB-ECOG (NCT03685461)
- Testing
- Electrocochleography
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Medical College of Wisconsin
Sensorineural Hearing Loss, Bilateral
Auditory Performances With Different Stimulation Depths in Cochlear Implanted Subjects Using a Fine Structure Strategy
Main objective: Investigate on new cochlear implanted patients whether the FineHearing strategy of the MED-EL cochlear implant gives better results on musical perception if the depth of stimulation (stimulation or not of the…
- Trial name
- NCT04591093
- Testing
- FineHearing Strategy with 10 more apical electrodes or with 10 more basal electrodes activated
- Where
- France
- Volunteers
- 32 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Unilateral Hearing Loss
Functional Magnetic Resonance Imaging Study of the Central Auditory System After Single Sided Deafness
The objective is to study the relation between the reorganization of the central auditory system, and the psychophysical deficits in binaural hearing in subjects with single sided deafness.
- Trial name
- SSD (NCT02534298)
- Testing
- functional magnetic resonance imaging
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Hearing Loss, Hearing Loss, Sensorineural
Cochlear Implant Recipients: Comprehensive Longitudinal Evaluation
This study aims to assess hearing and speech perception, as well as quality of life, in deaf patients of all ages before and after cochlear implantation, and to explore differences across age groups and treatment subtypes…
- Conditions
- Hearing Loss, Hearing Loss, Sensorineural, Deafness, Cochlear Implantation
- Trial name
- CIRCLE (NCT07380269)
- Testing
- Cochlear Implantation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Hearing Loss, Hearing Loss, Sensorineural
Optimizing Bilateral and Single-sided-deafness Cochlear Implants for Functioning in Complex Auditory Environments
Cochlear implants (CIs) are devices that partially restore hearing for people with severe to profound hearing loss. This research focuses on CI users who use bilaterally implanted devices (two CIs, one on each side) and also…
- Conditions
- Hearing Loss, Hearing Loss, Sensorineural, Cochlear Hearing Loss
- Trial name
- NCT06305039
- Testing
- Diagnostic tests of cochlear implant or acoustic hearing function, Targeted aural rehabilitation of the poorer performing ear
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Maryland, College Park
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Characterisation of Low Frequency Hearing and Vestibular Function in Patients Undergoing Cochlear Implantation
The study will follow a cohort of CI-candidates becoming CI-user, till two years postoperative. A through-out assessment of both their audiological and vestibular status will be carried out at multiple fixed timepoints over 2…
- Trial name
- NCT06021132
- Testing
- cochlear implant
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Aalborg University Hospital
Sensorineural Hearing Loss, Deafness
Cochlear Implant and Vestibular Function.
This study investigate weather one type of cochlear implant (CI) surgery (insertion of the electrode via paracentesis of the round window (RWA)) leads to less vertigo than another type of CI surgery (cochleostomy).
- Conditions
- Sensorineural Hearing Loss, Deafness, Hearing Loss
- Trial name
- NCT02584361
- Testing
- Round window approach, Cochleostomy
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cochlear Function Disorder
Cochlear Implantation Experience
Evaluating the effectiveness and outcomes of cochlear implants in individuals with hearing loss,identifying common complications or risks associated with cochlear implantation, including device failure, surgical complications, or…
- Trial name
- NCT06896864
- Testing
- cochlear implantation
- Volunteers
- 150 people
- Sponsor
- Assiut University
Hearing Loss
ICF in Cochlear Implant Users
The current project proposes a multi-center prospective follow-up cohort study aiming to realize an international framework to classify human functioning and disability in Cochlear Implant (CI) recipients using a standardized ICF…
- Trial name
- NCT04611555
- Where
- 5 sites in Australia, Belgium and 3 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Hearing Loss, Cochlear
Electrocochleography Function for Monitoring Residual Hearing
This trial is a pilot study to assess the feasibility of using Electrocochleography recorded from a cochlear implant intra-operatively in real time to monitor the progress of its insertion. Correlation between: 1.
- Trial name
- ECochG (NCT03848338)
- Testing
- Electrocochleography
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cochlear Trauma, Vestibular Disorder
Vestibular Function in Cochlear Implants
The objective of this study is to identify possible preoperative risk factors including genetic background and to suggest the optimal test battery of vestibular function in cochlear implant recipients
- Conditions
- Cochlear Trauma, Vestibular Disorder, Deafness, Bilateral
- Trial name
- NCT05795530
- Testing
- cochlear implantation
- Where
- Czechia
- Volunteers
- 57 people
- Sponsor
- Charles University, Czech Republic
Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency
Inventory of Radiological and Vestibular Function in Cochlear Implant Candidates
In 2014 radiological lesions at one or more semicircular canals (SCC) were described using CT \& MR imaging in subjects presenting advanced hearing and vestibular deterioration caused by the p.P51S mutation in COCH.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency, DFNA9, Radiology
- Trial name
- NCT04066270
- Testing
- video nystagmography
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Jessa Hospital
Hearing Loss
Evaluating the Revised WORQ in CI Users
The Work Related Questionnaire (WORQ) is a 59-item questionnaire of which each item represents an International Classification of Functioning and disability category.
- Trial name
- NCT04602780
- Where
- 5 sites in Australia, Belgium and 3 more
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Usher Syndrome, Cochlear Implantation
Auditory Neural Function in Implanted Patients With Usher Syndrome
Usher syndrome (USH) causes extensive degeneration in the cochlear nerve (CN), especially in CN fibers innervating the base of the cochlea.
- Trial name
- NCT04906135
- Testing
- Experimental manipulation of stimulation parameters
- Where
- 4 sites in United States
- Volunteers
- 29 people
- Sponsor
- Ohio State University
Sensorineural Hearing Loss
Clinal Evaluation of Navigation Based Functional Ear Surgery Using Image Guided and Robotically Assisted Techniques
To assess the feasibility of achieving a minimally invasive access to the inner ear through the navigation-based HEARO procedure and subsequently insert the electrode array of the cochlear implant through the access.
- Trial name
- EAR2OS (NCT03746613)
- Testing
- HEARO
- Where
- Belgium
- Volunteers
- 3 people
- Sponsor
- Prof. Vedat Topsakal
Hearing Loss, Deafness
Auditory-Cognitive Training to Optimize Outcomes for Older CI Users
The proposed study will investigate whether an auditory brain training program can improve cochlear implant (CI) outcomes in older post-lingually deafened CI users.
- Trial name
- ARCog (NCT05176561)
- Testing
- Auditory-Cognitive Training, Non-auditory Cognitive Training
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gallaudet University
Vestibular Schwannoma
Remote Ischemic Preconditioning in Vestibular Schwannoma Surgery
Vestibular schwannomas are primarily benign (WHO grade I) tumors originating from the Schwann cells of the vestibular nerve and are among the most common tumors of the skull base.
- Trial name
- RIC-VS (NCT05567341)
- Testing
- Remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Hospital Tuebingen
Hearing Loss
fNIRS in Pediatric Hearing Aids
Pilot phase. Monocentric, non-controlled, non-randomized, open-label study evaluating the capacity of the functional near-infrared functional neuroimaging (fNIRS) technique to translate temporal cortical activity in response to a…
- Trial name
- FNIRS (NCT04696835)
- Testing
- speech audiometry
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Lille