Clinical trials: Coffee
Cardiovascular Diseases
The Effects of Unfiltered (Turkish) Coffee Consumption on Cardiovascular Risk Parameters
Purpose/Objective: The aim of this study is to investigate the impact of boiled unfiltered (Turkish) coffee consumption on the plasma cardiovascular risk parameters of healthy subjects.
- Trial name
- NCT03495336
- Testing
- coffee abstention phase, LR Coffee consumption, DR Coffee consumption
- Where
- Cyprus
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Ovarian Cancer
Phase 1 Dose Escalation of ArtemiCoffee
This is a phase I dose-escalation study of Artemisia annua (Aa) in patients with advanced ovarian cancer who have completed front-line chemotherapy with carboplatin and paclitaxel.
- Trial name
- NCT04805333
- Testing
- Artemisia annua 450mg, Artemisia annua 900mg, Artemisia annua 1350mg
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Frederick R. Ueland, M.D.
Obesity
Effect of Coffee Consumption on Appetite Traits in Overweight and Obesity
The effect of coffee consumption on appetite is not clear, there are studies that show an effect on the regulation of energy intake, reducing hunger and/or increasing satiety.
- Trial name
- NCT05774119
- Testing
- breakfast with coffee, breakfast with water
- Where
- Mexico
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Premature Atrial Contractions, Premature Ventricular Contractions
Coffee and Real-time Atrial and Ventricular Ectopy
Atrial fibrillation (AF) and heart failure (HF) are morbid, costly, and incompletely understood diseases that have reached epidemic proportions worldwide.
- Trial name
- CRAVE (NCT03671759)
- Testing
- Start: On Caffeine, Start: Off Caffeine
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Balanced, Postural; Defect
The Effect of Coffee Consumption on Balance
This study aims to investigate the effects of daily coffee consumption on balance performance in healthy university students. Caffeine is a widely consumed psychoactive substance that may influence neuromuscular control, reaction…
- Conditions
- Balanced, Postural; Defect, Coffee Consumption
- Trial name
- NCT07540559
- Testing
- Daily coffee consumption (self-reported exposure)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
COFFEE, Gastrointestinal Motility and Defecation Conditions
The Effect of Coffee and Hot Water on Gastroıntestınal Functıons
The aim of this study is to examine the effects of coffee and hot water consumption on gastrointestinal system functions after cesarean section performed under general anesthesia.
- Trial name
- NCT05980975
- Testing
- Coffee, Hot water
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Mersin University
Sleepiness
Effect of Countermeasures on Nocturnal Driving Performance
Sleep deprivation induces degradation of night-time driving ability via sleepiness. Because of conflicts between physiological needs and social or professional activities, it is necessary to develop affordable countermeasure to…
- Trial name
- KILLSLEEP (NCT01070004)
- Testing
- Real driving situation, Driving simulator
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Diet Modification, Cardiovascular Risk Factor
Bioavailability and Beneficial Properties of Coffee and Cocoa Bioactive Compounds
The aim of this study will be to define the bioavailability and the beneficial properties of coffee bioactive compounds. Moreover, the contribution of cocoa-based products containing coffee to the pool of circulating metabolites…
- Conditions
- Diet Modification, Cardiovascular Risk Factor, Nutritional and Metabolic Diseases
- Trial name
- P4L (NCT03166540)
- Testing
- cup of espresso coffee, cocoa-based products containing coffee
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Parma
Excess Intake of Macronutrients, Excess Intake of Micronutrients
Water and Coffee Intervention in Humans
39 healthy subjects without medication (except oral contraceptives) aged 20-70 years are recruited via advertisements or through telephone contacts with individuals that had previously participated in population-based cohort…
- Conditions
- Excess Intake of Macronutrients, Excess Intake of Micronutrients, Vasopressin Low
- Trial name
- NCT06165185
- Testing
- Water, Coffee, Control
- Where
- Sweden
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Region Skane
Postdural Puncture Headache
Effect of Coffee on Postdural Puncture Headache After Cesarean Section
The purpose of this study is to investigate the effects of postoperative coffee consumption on postdural puncture headache (PDPH) and analgesic use in women undergoing cesarean section with spinal anesthesia.
- Trial name
- NCT07410741
- Testing
- Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Overweight
Effects of Caffeinated and Decaffeinated Coffee on Body Weight and Glucose Tolerance
Habitual consumption of coffee may have substantial beneficial effects on glucose metabolism according to recent findings of epidemiological studies in the U.S., Europe, and Japan.
- Trial name
- NCT00305097
- Testing
- Decaffeinated coffee, Caffeinated coffee, No coffee
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
High Blood Pressure
Effects of High Caffeine Content Coffee on Blood Pressure in Young Adults
The purpose of this study is to help further the understanding of the effects of commercially available high-caffeine containing coffee on blood pressure in healthy adult subjects.
- Trial name
- NCT04060225
- Testing
- Coffee
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Diabetes Mellitus
Effect of Coffee Consumption on the Glycemic Index of Khalas Dates Tested in Healthy and Diabetic Subjects
The aim of this study was to evaluate the composition of Khalas, a very common type of dates used in the UAE and to determine the effects of drinking Arabic coffee on the results of GI tests in both healthy and diabetic subjects.
- Trial name
- NCT01422668
- Testing
- Khalas dates
- Where
- United Arab Emirates
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Cardiovascular Disease
The Effect of High and Low Roasted Coffee on Vascular Response
Evidence suggests that a diet rich in plant phenolic compounds may induce beneficial vascular effects. Coffee is a good source of phenolic compounds called chlorogenic acids (CGA), however the level of CGA is reduced during the…
- Trial name
- NCT01813981
- Testing
- Low roast coffee, High roast coffee, Control (Caffeine dissolved in water)
- Where
- 2 sites in United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Reading
Healthy
The Effect of Coffee on People with High Intensity Exercise and the Characteristics of Caffeine Metabolism
The purpose of this project is to explore the relationship between the effect of coffee on exercise performance and caffeine metabolism.
- Trial name
- NCT06712667
- Testing
- Caffeine content
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Brain-derived Neurotrophic Factor (BDNF), Cognitive Function
Whole Coffee Fruit Concentrate Pilot Study 1
The purpose of this pilot study is to evaluate the potential effects of whole coffee fruit concentrate (WCFC, Neurofactor), a product that elevates circulating brain-derived neurotrophic factor (BDNF), on cognition and mood in…
- Conditions
- Brain-derived Neurotrophic Factor (BDNF), Cognitive Function, Affect
- Trial name
- WCFC (NCT01965795)
- Testing
- Whole Coffee Fruit Concentrate (WCFC), Nutrim
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy
Coffee, Exercise, and Oxidative Stress
Coffee is one of the most widely consumed beverages. It contains polyphenols (chlorogenic acids) and bioavailability of these bioactive compounds is now somewhat well understood.
- Trial name
- NCT01832701
- Testing
- Coffee
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Prediabetes
Effects of Coffee Consumption on Metabolic Markers in Adults With Prediabetes and Obesity
Epidemiological studies have shown an inverse association between coffee consumption and risk of type 2 diabetes. However, the randomized controlled trials in prediabetes are limited to evaluate the effects of coffee.
- Trial name
- NCT06330727
- Testing
- Coffee capsule, Corn starch capsule
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Coffee
Acute Effects of Instant Coffee in Capsule vs Beverage Form on Plasma Metabolites
This study is designed to evaluate the acute effect of consuming a cup of instant coffee on circulating metabolites and to evaluate whether ingestion of instant coffee in the form of a capsule has a similar effect on circulating…
- Trial name
- NCT07051291
- Testing
- Instant Coffee Capsule, Instant Coffee Beverage
- Where
- Singapore
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Fatigue, Tachycardia
Effect of Caffeine on Heart Function
The primary objective of this study is to assess the effect of an energy drink on ventricular repolarization as measured by the interval between the cardiac Q wave and the cardiac T wave (QT interval)obtained from the body…
- Trial name
- NCT02401776
- Testing
- Monster Energy Drink, Coffee
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin