Clinical trials: Coffee
Sleep, Mood
A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products
This is a virtual, single-arm clinical trial that will last 12 weeks. Participants will trial three different products, each for 4 weeks.
- Conditions
- Sleep, Mood, Caffeine Withdrawal, Anxiety
- Trial name
- NCT06146517
- Testing
- Clevr Sleeptime, Clevr Matcha, Clevr Chai
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Clevr Blends
Cognitive Change
Acute Effects of Naturally Occurring Tea and Coffee-based Ingredients on Cognitive Performance
This study is a double-blind, randomized, three-arm, single-dose, placebo-controlled crossover trial of forty (40) apparently healthy male and female participants.
- Trial name
- NCT06062186
- Testing
- AmaTea Guayusa Extract, Lion's Mane
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Healthy
A Clinical Study of How Coffee and Tea Affect Enlicitide in Healthy Volunteers (MK-0616-040)
The goal of this study is to learn what happens to enlicitide in a person's body over time when enlicitide is taken at the same time as coffee or tea.
- Trial name
- NCT07044479
- Testing
- Enlicitide
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Dietary Supplement, Exercise
Coffee Increases Physical and Cognitive Performance Both in Men and Women
The impact of caffeine habituation on acute responses to different doses of caffeinated coffee has received minimal attention. This study aimed to investigate the effects of different doses of coffee on physical and cognitive…
- Trial name
- NCT07474753
- Testing
- Low Dose Caffeine (LCOF), Moderate Dose Caffeine (MCOF), High Dose Caffeine (HCOF)
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy Subjects
The Effects of Coffee
In this study, participants will be eligible to participate in a paid research study that will examine the effects of regular coffee drinking. The study takes approximately 2 hours total, 55 min. on 2 separate days.
- Trial name
- NCT00336271
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- American University
Muscle Recovery, Oxidative Stress
Development of a Coffee Pulp Infusion as a Strategy for Recovery After Moderate Physical Exercise in a Healthy Population.
The goal of this clinical trial is to learn if a coffee pulp infusion works to improve muscle recovery after moderate physical exercise in a healthy adult population.
- Conditions
- Muscle Recovery, Oxidative Stress, Inflamation, Muscle Damage
- Trial name
- COPULP-REC (NCT07875699)
- Testing
- Two 250 mL infusions per day (one in the morning and one at night) for 45 consecutive days.
- Where
- Spain
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- David Ramiro Cortijo
Blood Pressure, Heart Rate
The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Some Physiological Parameters
The goal of this clinical trial is to investigate whether a three-day consumption of honey-sweetened black tea, green tea, and coffee will have an effect on blood pressure, heart rate, and blood glucose.
- Conditions
- Blood Pressure, Heart Rate, Blood Glucose
- Trial name
- NCT07002307
- Testing
- Warm water at 35 oC, Coffee, Honey-sweetened coffee
- Where
- Nigeria
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Uyo Teaching Hospital
Hypertension
Effects of Coffee Versus Hibiscus Tea Consumption During Prolonged Sitting on Blood Pressure and Heart Rate
Modern lifestyles often involve long periods of sitting, which can increase the risk of heart problems, obesity, and other health issues. Diet also plays a key role in heart health.
- Trial name
- NCT07159152
- Testing
- Coffee, Hibiscus drink
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Saud University
Prediabetes
Effects of Coffee Consumption on Metabolic Markers in Adults With Prediabetes and Obesity
Epidemiological studies have shown an inverse association between coffee consumption and risk of type 2 diabetes. However, the randomized controlled trials in prediabetes are limited to evaluate the effects of coffee.
- Trial name
- NCT06330727
- Testing
- Coffee capsule, Corn starch capsule
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Overweight
Health Effects of Coffee Consumption
Epidemiological studies have indicated a positive health impact of coffee. Nevertheless, intervention studies testing the effect of daily coffee consumption over a longer period are lacking so far.
- Trial name
- DüsselKaffee (NCT01759329)
- Testing
- test coffee, control coffee
- Where
- Germany
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- West German Center of Diabetes and Health
Obesity, Overweight
Metabolic Effect of New Foods Through Gut-brain Axis
A diet high in easily obtained energy-dense foods leads to the problems of overweight and obesity common in the developed world. Foods enriched with fiber or bitter compounds may increase satiety and decrease energy intake.
- Trial name
- CHECKMATE (NCT01851304)
- Testing
- Satiety of breads, Satiety of puddings
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Federico II University
High Blood Pressure
Effects of High Caffeine Content Coffee on Blood Pressure in Young Adults
The purpose of this study is to help further the understanding of the effects of commercially available high-caffeine containing coffee on blood pressure in healthy adult subjects.
- Trial name
- NCT04060225
- Testing
- Coffee
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Cardiovascular Disease
The Effect of High and Low Roasted Coffee on Vascular Response
Evidence suggests that a diet rich in plant phenolic compounds may induce beneficial vascular effects. Coffee is a good source of phenolic compounds called chlorogenic acids (CGA), however the level of CGA is reduced during the…
- Trial name
- NCT01813981
- Testing
- Low roast coffee, High roast coffee, Control (Caffeine dissolved in water)
- Where
- 2 sites in United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Reading
Polymorphism, Sleep Disorder
Polymorphisms, Caffeine and Sleep Disorders
Screening of a population of volunteer workers recruited on the occasion of their occupational health visit, within the Ministry of Defense and civil enterprises.
- Conditions
- Polymorphism, Sleep Disorder, Coffee-Workers' Disease
- Trial name
- SOCAF (NCT03855774)
- Testing
- Polymorphisms
- Where
- France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Anesthesia, Aspiration
How do You Take Your Coffee Before Anesthesia
Undergoing anesthesia requires patients to fast pre-operatively to allow the stomach to empty and prevent aspiration pneumonia but patients are allowed to drink "clear" liquids up to 2 hours before surgery.
- Conditions
- Anesthesia, Aspiration, Fasting
- Trial name
- NCT04786691
- Testing
- Addition of half and half to coffee, Addition of non-dairy creamer to coffee, Black
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Healthy
The Effect of Green Coffee Extract on Blood Glucose Homeostasis in Healthy Adults
Green coffee extract (GCE) supplementation has been shown to induce favourable health benefits on glucose metabolism and weight management.
- Trial name
- NCT06137066
- Testing
- 200mg GCE +200mg ALA, 200mg GCE +400mg ALA, 200mg GCE + 200mg DHB
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. Chris McGlory, PhD
Coffee
Coffee Intake Biomarker Validation and Association With Respiratory Diseases
This proposed project aims to identify and validate biomarkers of coffee exposure in the Singapore population, and assess the association between coffee consumption (via biomarker measurements) and risk of respiratory diseases in…
- Trial name
- NCT07391696
- Testing
- Coffee A, Coffee B, Tea
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Stress, Signs and Symptoms, Digestive
The Acute Effect of Coffee Consumption on Stomach, Self-reported Gastrointestinal Symptoms and Stress.
This study investigated the acute effect of the consumption of four different kinds of coffee (hot and cold instant coffee, cold espresso and hot filter coffee) with the same caffeine content on salivary gastrin, cortisol and…
- Conditions
- Stress, Signs and Symptoms, Digestive, Blood Pressure, Increased Secretion of Gastrin
- Trial name
- NCT02253628
- Testing
- Cold espresso, Hot instant coffee, Cold instant coffee
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Obesity, Inflammation
Effects of Different Coffee Amounts on Energy Intake, Appetite, Glucose Metabolism and Inflammatory Markers
The purpose of the study is to investigate whether different doses of caffeinated coffee consumption has acute effects on subjective appetite feelings, energy intake and biochemical markers related to appetite, inflammation and…
- Trial name
- NCT01495754
- Testing
- coffee
- Where
- Greece
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Leukocytosis, Triglycerides
Acute High Fat Bulletproof Coffee vs Black Coffee on Metabolism, Inflammation and Cognitive Function in Healthy Adults
This study will determine whether acute ingestion of a high fat "Bulletproof Coffee" will lead to changes in plasma triglycerides, immune cell function, as well as cognitive function when compared to a black coffee.
- Conditions
- Leukocytosis, Triglycerides, Cognitive Function, Inflammatory Response
- Trial name
- NCT04307979
- Testing
- High-fat coffee, Black coffee
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia