Clinical trials: Cognition
Students of Undergraduate School of Nursing
Promoting Students' Development of Ultimate Concern Care Strategies
Teaching intervention
- Trial name
- NCT07532616
- Testing
- Teaching
- Where
- Taiwan
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Hearing Disorders and Deafness
ListenFuture-Listening for Their Future: Deaf and Hard-of-Hearing Adolescents
ListenFuture, a nation-wide multidisciplinary project, brings new knowledge on complex associations between listening, cognition, language, literacy, and psychosocial wellbeing in deaf and hard-of-hearing (DHH) adolescents.
- Trial name
- ListenFuture (NCT07416292)
- Where
- 7 sites in Finland
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Heikki Löppönen
Cognitive Impairment, Stroke
Addressing Problems in Managing Daily Tasks Due to Poststroke Cognitive Impairments
The purpose of this study is to investigate feasibility aspects of an intervention targeting problems in managing daily tasks due to mild-to-moderate poststroke cognitive impairments.
- Trial name
- NIOTI-stroke (NCT05829421)
- Testing
- Impairment-specific occupational therapy (OT) intervention
- Where
- 4 sites in Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emma Ghaziani
Mild Cognitive Impairment, Mild Dementia
Validation of the German Version of the Amsterdam Instrumental Activities of Daily Living Questionnaire®
Pretest and validation of the German version of the Amsterdam instrumental activities of daily living questionaire short in elderly people with normal cognition, mild cognitive impairment (MCI) or mild dementia in the German…
- Trial name
- NCT04012398
- Testing
- Amsterdam IADL Questionnaire short, German version
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Chronic Kidney Diseases, Kidney Transplantation
MRI Technical Development and Applications in Kidney Disease
Magnetic resonance imaging (MRI), as a non-invasive and non-contrast enhanced technique, has the potential to improve patient health care and management. The overall objective of proposed project is to: 1.
- Conditions
- Chronic Kidney Diseases, Kidney Transplantation, Dialysis, Cognition Disorders
- Trial name
- NCT02421497
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cognition in Schizophrenia
Study of the Effects of Mecamylamine and Varenicline in Schizophrenia
We are conducting this study to find out if blocking or partially stimulating the effects of nicotine in the brain can affect memory and concentration. Nicotine is the addictive drug found in tobacco products.
- Trial name
- NCT00455650
- Testing
- Mecamylamine, Varenicline
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Malnourishment
Cognitive Effects of Omega-3 Supplements in Children With Mild to Moderate Malnutrition
Adequate nutrition is one of the critical biological processes to learning and cognitive development of children. And is understandable that malnourishment affect these processes.
- Trial name
- NCT01199120
- Testing
- Omega 3
- Where
- Mexico
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Alcohol Use Disorder, Intermittent Explosive Disorder
Neural Correlates During Alcohol Intoxication
Alcohol intoxication is responsible for a large proportion of violent crime/assault and personal injury in our society. While a number of variables have been associated with alcohol-related aggression, high trait aggression and…
- Trial name
- NCT06118580
- Testing
- Alcohol (Ethanol)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Bipolar Disorder
The Bipolar Illness Onset Study (the BIO Study)
This longitudinal study aims to identify 1) a composite blood-based biomarker, 2) a composite electronic Smartphone-based biomarker and 3) a neurocognitive signature for bipolar disorder
- Trial name
- BIO (NCT02888262)
- Where
- Denmark
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Age-related Macular Degeneration, Dementia
Words on the Brain: Can Reading Rehabilitation for Age-Related Vision Impairment Improve Cognitive Functioning?
Age-related vision impairment and dementia both become more prevalent with increasing age. Research into the mechanisms of these conditions has proposed that some of their causes (e.g., macular degeneration/glaucoma and…
- Conditions
- Age-related Macular Degeneration, Dementia, Low Vision, Low Vision Aids
- Trial name
- WOTB (NCT04276610)
- Testing
- Low Vision Reading Rehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Alzheimer Disease, Mild Cognitive Impairment
TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory
The purpose of this study is to assess the effects of non-invasive brain stimulation on memory in cognitively unimpaired older adults and in patients amnestic mild cognitive impairment (aMCI) due to Alzheimer's disease (AD).
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Aging
- Trial name
- NCT04294888
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alzheimer Disease, Dementia
Exploratory Clinical Study and Validation of Blood Biomarkers for Alzheimer's Disease
This is a 24-month, monocentric, exploratory and observational clinical study aimed at developing and validating a blood-based diagnostic test for Alzheimer's disease (AD).
- Conditions
- Alzheimer Disease, Dementia, Neurodegenerative Disorders, Cognitive Decline
- Trial name
- ADKIT (NCT07294586)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Amoneta Diagnostics SAS
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Aging
Oxytocin's Effect on Socioemotional Aging
This study will investigate the extent to which intranasal oxytocin affects changes in social decision making and evaluations of others.
- Trial name
- NCT01823146
- Testing
- Oxytocin spray
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Florida
Epilepsy
Effects of Keppra on Thinking, Emotions, and Balance in Elderly Healthy Volunteers
Epilepsy is a common disorder with an incidence of about 6 per 1000. The incidence progressively increases above age 50. By age 75, the incidence is two to three fold compared with any age group.
- Trial name
- NCT00221988
- Testing
- Levetiracetam (Keppra)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Cognitive Dysfunction
Effects Of An 8-Weeks Mindfulness-based Intervention In Individuals With Subjective Cognitive Decline
The European Commission Horizon 2020 programme has funded the SCD-WELL trial to investigate the efficacy of mindfulness-based training to reduce anxiety in individuals with Subjective Cognitive Decline (SCD), in comparison to an…
- Trial name
- SCD-WELL (NCT03005652)
- Testing
- Mindfulness weekly courses for 8 weeks, Health education weekly courses for 8 weeks
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Parkinson Disease
Neural Correlates of Cognition in Parkinson's Disease
Cognitive impairment in Parkinson's disease (PD) has far-reaching effects on both motor outcomes and quality of life in PD patients.
- Trial name
- NCT02975193
- Testing
- Computer task assessing cognition, Impulsive-Compulsive Disorders in Parkinson's Disease, Deep Brain Stimulation Surgery
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cognition, Mood
Genistein, Equol, Cognitive Function and Mood: Acute. (GECFAMa)
Isoflavones (ISF) are naturally occurring compounds that can provide protective benefits for certain domains of cognitive function.
- Trial name
- GECFAMa (NCT07742514)
- Testing
- Genistein, Equol
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Reading
Healthy
Acute Effect of a Standardized Botanical Blend Rich in Polyphenols on Cognitive Functions in Healthy Students
Available literature suggests that flavanols-rich foods, and more especially monomeric flavanols-rich foods such as grape, can have an acute effect on cognitive functions via different mechanisms such as cerebral blood flow…
- Trial name
- NCT03508206
- Testing
- SBRP
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Activ'inside
Cognition
Acute Effects of Supplemental Oxygen on Memory Testing in Healthy Adult Volunteers
Forty healthy adults (i.e., not recruited with respect to any particular diagnosis) are each alternately provided with supplemental oxygen and air via nasal cannula at about 6 Liters per Minute (LPM), while completing memory…
- Trial name
- NCT06555484
- Testing
- Cross Over Assignment Supplemental Oxygen and Supplemental Air
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Inogen Inc.
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