Clinical trials: Cognitive/Functional Effects
Chronic Low-back Pain
Supplementation With Vitamin D3 on Chronic Low Back Pain Patient
The study was designed as a randomized double-blind placebo-controlled clinical trial with 8-week Vitamin D3 and physical activity intervention.
- Trial name
- NCT06082375
- Testing
- Vitamin D
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Healthy
Dual Site-Dual Channel Non-invasive Brain Stimulation for Language and Cognitive Function in Healthy Subjects
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in healthy.
- Trial name
- NCT03486808
- Testing
- IFG stimulation, DLPFC stimulation
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Schizophrenia
Effects of Cognitive Remediation Therapy on Schizophrenia Patients Through Functional Magnetic Resonance Imaging
Cognitive Remediation Therapy (CRT) can enhance cognitive performance in patients with schizophrenia improving clinical outcome. However, the neurobiological mechanism underlying cognitive improvement is not well understood.
- Trial name
- NCT01318850
- Testing
- Cognitive Remediation Therapy, Psychoeducation, Healthy controls
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Subjective Cognitive Decline (SCD)
Polyamine-enriched Diet in Elderly Individuals With Subjective Cognitive Decline
The overall objective of this study is to examine the effect of polyamine supplementation on cognitive performance and further characterization of individuals with subjective cognitive decline.
- Trial name
- SmartAge (NCT03094546)
- Testing
- Polyamine
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy Lifestyle
Effect of a School Intervention With Physical Activity on Executive Functions
Previous studies have indicated the relationship between physical activity and cognitive performance, with movement being a promising tool for improving executive functions, especially during childhood, which is a period of…
- Trial name
- NCT06496503
- Testing
- Physical activity Protocol
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- State University of Londrina
Hot Flashes
Soy Isoflavone Tablets: Effects on Sleep, Quality of Life, Symptoms and Cognitive Function in Menopausal Women
The study was done to elucidate relationships between midlife women's self-reported hot flashes, neuropsychological symptoms, cognitive performance or sleep.
- Trial name
- NCT01401946
- Testing
- soy isoflavones
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Diabetes Type 2, Diabetes Type 1
Disentangling the Effect of Brain Insulin Resistance on Brain Health
People with diabetes are at increased risk of developing dementia, including Alzheimer's disease and vascular dementia. In addition, persons with diabetes have more pronounced age-related brain atrophy and cognitive difficulties…
- Trial name
- BIR 1 (NCT07374705)
- Where
- 3 sites in Denmark, Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henrik Bo Wiberg Larsson
Cognitive Function in Elderly
Effect of Acute Exercise on Cognitive Functions
To determine whether acute aerobic exercise versus resistance exercise effects cognitive function among older adults.
- Trial name
- NCT01241851
- Testing
- Aerobic exercise, Resistance exercise
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Type 1 Diabetes Mellitus
The Effect of Cocoa Flavanol on the BOLD Response and Cognitive Function in Type 1 Diabetes
Type 1 Diabetes (T1D) is associated with microvascular changes in the brain, which can cause cognitive dysfunction. Cocoa flavanols (CF) can stimulate vasodilation, resulting in enhanced cerebral blood flow and better cognitive…
- Trial name
- NCT03452605
- Testing
- cocoa flavanol supplementation
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Healthy
Effects of Vitamin D3 Supplementation on Cognitive Function in Community Dwelling Older Adults
Ireland is predicted to have the highest older adult population growth of any European Union country. A substantial economic and social challenge of this projected growth is the increased incidence of cognitive impairment and the…
- Trial name
- NCT02804841
- Testing
- Cholecalciferol -Vitamin D3
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Depression
Emotional and Cognitive Control in Late-Onset Depression
This study may help identify how abnormalities in brain systems that control the ability to ignore irrelevant information may contribute to the development of depression in older adults.
- Trial name
- NCT01728194
- Testing
- Escitalopram, Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Memory, Cognitive Function Decline
Cognitive Effects of Bioavailable Curcumin
An estimated 50% of older adults complain of memory changes that worsen as they age. Although numerous commercially available dietary supplements claim cognitive benefits, relatively few well-designed, longitudinal…
- Trial name
- NCT07251985
- Testing
- Curcumin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Cognitive Function
Fenfluramine and Cognition
In this study, the investigators will investigate the cognitive effects of fenfluramine, a drug that directly stimulates the release of serotonin in the brain and positively modulates σ1 function.
- Trial name
- FEN&Cognition (NCT05026398)
- Testing
- Fenfluramine
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Elderly Adults, Mild Cognitive Impairment
Agility Training and Its Relations in Elderly Adults With and Without MCI
The following three-part proposal will focus on the effects of agility training as well as the relationship between agility ability and motor and cognitive function, and risk of falls in elderly adults with or without mild…
- Conditions
- Elderly Adults, Mild Cognitive Impairment, Healthy
- Trial name
- NCT05537363
- Testing
- Health education, Multicomponent training, Agility training
- Where
- Taiwan
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cognitive Enhancement During Exercise
Effect of Huperzine A on Cognitive Function and Perception of Effort During Exercise
This study evaluates the effects of acute huperzine A ingestion prior to exercise on cognitive function and perceived effort in exercise-trained individuals.
- Trial name
- NCT03445104
- Testing
- Huperzine A
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Central Fatigue, Altitude Training
Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training
This randomized controlled trial investigates the effects of hot spring balneotherapy on central fatigue elimination in adolescent rowers undergoing altitude training at approximately 1600 meters (Tengchong, Yunnan).
- Conditions
- Central Fatigue, Altitude Training, Cognitive Impairment, Hydrotherapy
- Trial name
- HSCF-AHT (NCT07615478)
- Testing
- Natural recovery, Hot water immersion, Hot spring balneotherapy
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Bariatric Surgery, Alcohol Consumption
Effect of Moderate Alcohol Consumption to Cognitive Functioning After Roux-en Y Gastric Bypass
Objectives: Alcohol metabolism is changed in gastric bypass patients, leading to faster resorption and higher alcohol peak concentrations in blood.
- Conditions
- Bariatric Surgery, Alcohol Consumption, Cognitive Function
- Trial name
- NCT02380950
- Testing
- 250 ml alcohol consumption
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- eSwiss Medical & Surgical Center
Effect of Superstarch on Soccer Performance
Superstarch and Physical/Cognitive Performance Following a Simulated Soccer Game
To assess the efficacy of a hydrothermally modified starch supplement (Superstarch made byGeneration UCAN) vs isoenergetic placebo (glucose) on exercise performance, execution of specific soccer skills, and on cognitive function…
- Trial name
- NCT02667340
- Testing
- Superstarch
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Aging, Healthy Aging
Cognitive Vitality Pilot Study
This study's purpose is to evaluate the effects of a dietary supplement on cognitive function and psychological well-being in community-dwelling older adults aged 55+.
- Conditions
- Aging, Healthy Aging, Cognition, Memory
- Trial name
- NCT07208279
- Testing
- Axolt Brain Supplement
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cognitive Function, Gaming Performance
Effects of Paraxanthine Supplementation on eSport Performancre
This study will evaluate the effects of daily paraxanthine supplementation on electronic gaming performance, cognitive function, sleep quality, and autonomic responses in healthy adult gamers.
- Trial name
- EPX (NCT07533045)
- Testing
- Paraxanthine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lindenwood University