Clinical trials: Cognitive/Functional Effects
Physiological Stress, Cognitive Performance
Dietary Intervention With Brain-friendly Diet
To evaluate the effect of dietary intervention on metabolic risk profile, and on potential simultaneous changes in physiological and cognitive functions and to collect a unique database using state-of-the-art technologies on…
- Conditions
- Physiological Stress, Cognitive Performance, LDL Cholesterol
- Trial name
- BRAVE (NCT03346486)
- Testing
- Control diet, Intervention diet
- Where
- Finland
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fazer Group
Healthy Aging, Cognitive Decline
Cognitively Enriched Walking Program
Dementia currently affects more than 47 million people worldwide, its prevalence is forecasted to triple by 2050, and it has been reported to be one of the most costly disorders in Belgium.
- Conditions
- Healthy Aging, Cognitive Decline, Physical Inactivity
- Trial name
- NCT05500183
- Testing
- Cognitively enriched walking program, walking program
- Where
- 2 sites in Belgium
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University Ghent
Multiple Sclerosis, Relapsing-Remitting
Examining Effects of Ocrevus on Cognitive Fatigue Using fMRI
The purpose of this research study is to investigate the effectiveness of MS Disease modifying medications on cognitive fatigue in persons with relapsing remitting multiple sclerosis (RRMS).
- Trial name
- NCT04448977
- Testing
- Ocrevus
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Healthy
Acute Effects of Breakfast Compared With No Breakfast on Cognitive Function and Subjective State in 11-13 Year Old Children
This study is a school-based, randomised, controlled, parallel groups trial to examine the acute effect of breakfast (ready-to-eat-cereal and milk) vs.
- Trial name
- NCT03979027
- Testing
- Breakfast: ready-to-eat-cereal and milk
- Where
- United Kingdom
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Cognition, Inflammation
Effects of Peanut Intake on Cognitive Functions
The study will test the effects of Peanuts on task-related brain activation and cognitive functions in older adults with memory complaints.
- Trial name
- NCT05532007
- Testing
- Peanuts, Habitual Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Cognitive Performance, Mood
Effects on Cognitive Functions and Mood of Food Products Rich in Polyphenols
The purpose of this study is to investigate effects of a selected food product rich in polyphenol on cognitive performance and mood.
- Conditions
- Cognitive Performance, Mood, Cardiometabolic Risk Markers
- Trial name
- NCT02243956
- Testing
- Flavanol rich food product
- Where
- Sweden
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Lund University
Healthy Adults With Subjective Memory Complaints
Effects of Deer Bone Extract NS on Improvement in Cognitive-Bio-Markers of Cognitive Functions
This study aims to elucidate the effects of deer bone extract NS on cognitive function improvement and its safety in healthy adults aged 40 to 65 years who report decline in subjective cognitive functions using multimodal…
- Trial name
- NCT02379481
- Testing
- NS 550mg, NS 1100mg
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Mood, Cognitive Performance
The Effects of A Proprietary Spearmint Extract on Cognitive Performance
This study was designed to evaluate the chronic effects of a proprietary spearmint extract over 90 days of supplementation on aspects of cognitive performance (cognitive function and active reaction time), subjective mood, and…
- Conditions
- Mood, Cognitive Performance, Sleep
- Trial name
- NCT02518165
- Testing
- Proprietary spearmint extract
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Healthy
Scopolamine Challenge Study
It is hypothesized that PF-05212377 (SAM-760) will reverse scopolamine induced cognitive impairments in healthy adults subjects.
- Trial name
- NCT01213355
- Testing
- Scopolamine, PF-05212377, Donepezil
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Pfizer
Creatine Supplementation, Exercise Ergogenics
Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men
This study evaluates whether 7-day creatine monohydrate supplementation affects cognitive function after high-intensity interval training (HIIT) in active young men.
- Trial name
- HIITCRECOG (NCT07534293)
- Testing
- Creatine Monohydrate, High Intensity Interval Training
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitas Negeri Malang
Muscle, Cognitive Functioning
This Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65.
In this study, participants will be assigned to receive HMB, 2-HOBA, a combination of both, or a comparison supplement for a set period of time.
- Conditions
- Muscle, Cognitive Functioning, Geriatric, Ageing and Geriatric Health
- Trial name
- H2AGE (NCT07419633)
- Testing
- β-Hydroxy-β-methylbutyrate, 2-hydroxybenzylamine, β-Hydroxy-β-methylbutyrate and 2-hydroxybenzylamine
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Aging, Healthy Aging
10-week Yoga Practice Effect on Cognitive and Motor Function in Older Adults
Thirty-three healthy elderly people, who were classified into two age groups, participated in this study. All participants had not practiced yoga before and were asked not to perform any sports activities while the research was…
- Trial name
- BDNF (NCT04314921)
- Testing
- Yoga trainings
- Where
- Lithuania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Frail Elderly
Long-term Effects of Interventional Strategies to Prevent Cognitive Decline in Elderly.
The MAPT PLUS study is a two-year extension of follow-up of the patients included in the MAPT preventive study, after completion of the interventions. Subjects in the four groups of the MAPT study will be prospectively followed.
- Trial name
- MAPT-PLUS (NCT01513252)
- Testing
- Gröber and Buschke test
- Where
- 13 sites in France, Monaco
- Volunteers
- 1,028 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Conditions or Focus of Study: Cognitive Function Loneliness Aging Physical Activity
Wearable-Assisted Walking for Cognitive Function and Loneliness in Older Adults
Participants in the wearable-assisted walking group were asked to walk five days per week for approximately 30 minutes per session at moderate intensity.
- Trial name
- WAW-CogLon (NCT07650292)
- Testing
- Wearable-Assisted Walking Program
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan College of Performing Arts
Mental Fatigue
The Effect of Mental Fatigue on Upper Extremity Functional Performance
Mental fatigue (MF) is known to impair cognitive performance and may negatively affect physical performance. While its effects on lower-extremity functional performance have been investigated, little is known about the influence…
- Trial name
- NCT07645404
- Testing
- Mental Fatigue
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Polymorphosis, Cognitive Function
Effect of Gene Polymorphism on Cognitive Function
The goal of this observational study is to study the effect of gene polymorphism on cognitive improvement in response to exercise in healthy participants.
- Trial name
- NCT05879341
- Testing
- High intensitiy interval training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Cognition, Neurovascular Coupling Mechanism and Cognitive Function
The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults
The goal of this pilot clinical trial is to test whether transcranial photobiomodulation (tPBM), a non-invasive brain stimulation technique using near-infrared light, can improve brain blood flow regulation (neurovascular…
- Conditions
- Cognition, Neurovascular Coupling Mechanism and Cognitive Function, Neurovascular Control, Brain Aging
- Trial name
- NCT07209683
- Testing
- transcranial photobiomodulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Depression
Effects of Fish-oil on Mood and Cognitive Functions of Healthy Individuals
The investigators recently found a positive effect of omega-3 supplements on cognitive function in healthy individuals after 4 weeks (J of Psychopharmacology 2009, 23: 831-840).
- Trial name
- NCT01104194
- Testing
- omega-3 fatty acids supplements (fish oil)
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Balance, Cognitive Functions
Effects of Simultaneous Versus Sequential Motor-cognitive Task Training on Balance and Coordination Among Elderly Individuals
A randomized control trial will be done on elderly individuals in Community Homes of Rawalpindi/Islamabad. Motor-cognitive impairments impact the life of elderly individuals.
- Trial name
- NCT06967844
- Testing
- Simultaneous motor-cognitive task training, Sequential motor-cognitive task training
- Where
- Pakistan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Sedentary Lifestyle, Cognitive Ability, General
Classroom Standing Desks for Reducing Sitting Time in Children
In this trial the investigators aim to verify the potential impacts of a multi-level intervention with standing desks on behavior and cognitive function in children
- Trial name
- NCT03137836
- Testing
- Intervention
- Where
- Portugal
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Lisbon