Clinical trials: Cognitive/Functional Effects
Cognition, Mood
Investigation of the Acute Effects of Nepalese Pepper Extract (Zanthoxylum Armatum DC) on Cognitive Function, Mood and Gaming Performance in Young, Healthy, Competitive Gamers
The goal of this clinical trial is to learn if a Nepalese Pepper Extract (Zanthoxlum Armatum, ZA) supplement can improve cognitive performance and mental abilities in competitive gamers aged 16 to 34.
- Conditions
- Cognition, Mood, Gaming Performance, Fatigue
- Trial name
- NCT07047105
- Testing
- Nepalese Pepper (Zanthoxylum Armatum) extract 150mg, Nepalese Pepper (Zanthoxylum Armatum) extract 300mg, Caffeine 75mg
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Aging
Chronic Passive Heating in Healthy Older Adults
Aging is associated with a decline in cardiovascular health, cognitive function and losses in muscle strength, with half or more of those over age 65 suffering from two or more comorbidities (e.g., heart disease, type 2…
- Trial name
- NCT05618197
- Testing
- Passive heating
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Aging, Balance
Effects of Adapted Sports on Balance, Physical Function, and Cognitive Function in Older Adults
This randomized controlled study aims to investigate the effects of adapted sports exercises on balance, physical function, and cognitive function in older adults.
- Conditions
- Aging, Balance, Functional Mobility, Physical Function
- Trial name
- ASF (NCT07457996)
- Testing
- Adapted Sports Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Health and Wellbeing
A Single Group Study to Evaluate the Effects of a Multivitamin on a Range of Health and Wellbeing Outcomes.
This is a hybrid single-group clinical trial that will last 12 weeks. Participants will take 2 capsules daily with the first meal of the day in the morning. Participants will undertake blood tests at Baseline and Week 12.
- Trial name
- NCT06568146
- Testing
- Multivitamin Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness
Bipolar Disorder, Cognitive Impairment
Effects of Erythropoietin on Cognition and Neural Activity in Mood Disorders
The present trial consists of 2 sub-studies that investigate important novel aspects of treatment with erythropoietin (EPO) on cognitive dysfunction in bipolar disorder (BD) and recurrent unipolar depressive disorder (UD)…
- Conditions
- Bipolar Disorder, Cognitive Impairment, Unipolar Depression
- Trial name
- PreTEC-EPO (NCT03315897)
- Testing
- Erythropoietin, Saline
- Where
- Denmark
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Lars Vedel Kessing
Hypertension, Retinal Disorder
DETECT and Retinal Outcomes in Hypertension
The purpose of this study is to study the impact of blood pressure on cognitive performance.
- Conditions
- Hypertension, Retinal Disorder, Cognitive Impairment
- Trial name
- NCT01815567
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Emory University
Autophagy, Healthy Aging
Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy
The goal of this clinical trial is to learn if a dietary supplement called Miricell works to improve cellular health and signs of healthy aging in adults. It will also learn about the safety of Miricell.
- Trial name
- NCT07675200
- Testing
- Spermidine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Quality of Life, Cognitive Impairment
Effect of the Mindfulness-Based Health Promotion Program (MBHP) in the Elderly: a RCT
According to the World Health Organization (WHO), it is estimated that by 2025 the number of older people in Brazil will be approximately 33.4 million and it will be the sixth population in absolute numbers of the elderly in the…
- Conditions
- Quality of Life, Cognitive Impairment, Psychological
- Trial name
- NCT03706807
- Testing
- Mindfulness-Based Intervention, Cognitive Stimulation
- Where
- Brazil
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Centro Mente Aberta de Mindfulness
Mild Cognitive Impairment
Effects of Bidomain Cognitive and Aerobic Training on Cognitive Functioning in Mild Cognitive Impairment.
The study aims to assess the effects of Bidomain cognitive and aerobic training on both cognitive functioning and quality of life in individuals with mild cognitive impairment.
- Trial name
- NCT06867016
- Testing
- Combined Cognitive & Aerobics Training, Cognitive Training
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Alzheimer Disease, Early Onset
Theta-burst Stimulation on Cognitive Function in the Patients With Young-onset Alzheimer's Disease Dementia
Young-onset dementia (YOD) is a devastating condition, and it produces substantial psychosocial impacts on individual's functioning and family's care burden. Alzheimer's disease (AD) dementia is the most common type in YOD.
- Trial name
- NCT04042532
- Testing
- Theta-burst stimulation (TBS)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Bipolar Disorder, Cognitive Impairment
Effect of Action-Based Cognitive Remediation in Patients With Bipolar Disorder
PRETEC-ABC aims to assess the effect of a new form of cognitive remediation, Action-Based Cognitive Remediation (ABCR), in patients with bipolar disorder in remission on cognition, and to assess the neural assays for treatment…
- Trial name
- PRETEC-ABC (NCT03295305)
- Testing
- Action-Based Cognitive Remediation, Unstructured support group
- Where
- Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The Effect of Acupuncture Therapy on Cognitive Function in Post-COVID-19 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Background of study: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a common sequela after SARS-CoV-2 infection(COVID-19). Cognitive dysfunction is one of the most common debilitating symptoms in ME/CFS.
- Trial name
- NCT07357688
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Xi Wu
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Celiac Disease in Children, Celiac Disease in Adolescents
Effect of Adherence to a Gluten-Free Diet on Cognitive and Motor Dual-Task Performance in Adolescents Diagnosed With Celiac Disease
The aim of this cross-sectional observational study is to comprehensively examine the effects of adherence to a gluten-free diet on cognitive, motor, and psychosocial functions in adolescents aged 8-18 years diagnosed with celiac…
- Trial name
- NCT07382999
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Inonu University
Healthy
Cognitive Effects of Life Kinetik-Adapted Physical Activity Cards
The purpose of this study is to investigate the effects of physical activity cards integrated with Life Kinetik exercises on attention, short-term memory, cognitive flexibility, and problem-solving skills in middle school…
- Trial name
- NCT07335848
- Testing
- Life Kinetik Adapted Physical Activity Cards Training, Physical activity cards training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Enes Sucular
Mild Cognitive Impairment
The Effects of Diet on Mood, Cognition and Appetite
A previous study has found that the consumption of a high fat, low carbohydrate meal results in increased feelings of calmness, friendliness and an increase in subjective energy levels in comparison to a low fat, high…
- Trial name
- NCT01201616
- Testing
- High Fat Low Carbohydrate Diet, Low fat High Carbohydrate Diet
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Aging, Cognitive Decline
The Effect of a Single Bout of Balance and Coordination Exercise on Cognitive Function in Elderly People
Individuals of advanced age are at higher risk of cognitive deterioration.A single bout of aerobic exercise was found to improve cognitive functions.
- Trial name
- NCT03420365
- Testing
- Aerobic exercise
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Functional Abilities, Cognitive Abilities
Effect of Instrument-assisted Soft Tissue Mobilization on Functional and Cognitive Abilities in Elderly
PURPOSE: To determine the effect of Instrument-assisted soft tissue mobilization on functional and cognitive abilities in elderly. BACKGROUND: There is an increased interest in health care with growth of the older population.
- Trial name
- IASTM-AGE (NCT07208630)
- Testing
- Instrument-assisted soft tissue mobilization, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Complication, Cognitive Retention Disorder
Methylprednisolone Combined Electric-acupuncture on Cognitive Function
Postoperative cognitive dysfunction (POCD) refers to the patients in the central nervous system complications after general anesthesia and clinical manifestations of mental disorder, anxiety, personality changes, impaired memory…
- Trial name
- NCT02535039
- Testing
- Methylprednisolone, Physiological saline
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Hyperextension Injury of Neck
Effects of Cervical Hyperextension on Cervical Blood Flow, Cerebral Oximetry and Cognitive Functions.
The goal of this observational study is to determine the effects of cervical hyperextension on cerebral oximetry and cognitive functions in healthy individuals without other additional factors such as anesthesia and surgical…
- Trial name
- NCT05576857
- Testing
- Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Duzce University