Clinical trials: Cognitive/Functional Effects
Central Nervous System Disease, Cerebrovascular Accident
Brain Processing of Language Meanings
This research trial will study discourse processing-that is, how the brain processes the meaning of language. It will examine, for example, how words and sentences are interpreted in cases where more than one meaning is possible.
- Conditions
- Central Nervous System Disease, Cerebrovascular Accident, Craniocerebral Trauma, Head Injury
- Trial name
- NCT00005004
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Mild Cognitive Impairment
The Effect of Consumption of Almonds and Snack Mix Daily for 6 Months on Cognitive Function in Older Adults
Cognitive impairment is also a major risk factor for development of dementia later in life. Findings from recent studies suggest that the there are many nutrients contained in foods that may be important in cognitive function in…
- Trial name
- NCT03093896
- Testing
- snack mix, almonds, 1.5 oz, almonds, 3 oz
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tufts University
Healthy
Terrestrial Trunked Radio (TETRA) and Cognitive Functions in Healthy Subjects
The purpose of this study is to analyse a possible effect of radiofrequency (RF) fields used for Terrestrial Trunked Radio (TETRA) of brain activity and cognitive functions in occupationally exposed subjects.
- Trial name
- TETRA (NCT01117597)
- Testing
- low RF exposure level, high RF exposure
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Cognitive Impairment, Aging
Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Cognitive Impairment
The purpose of this research is to investigate the impact of overground walking as a part of a rehabilitation program on the increase in Brain-derived neurotrophic factor (BDNF) levels, decrease in IL-6 levels, decrease in hs-CRP…
- Trial name
- NCT06029920
- Testing
- Overground Walking
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Healthy
Effects of Docosahexaenoic Acid (DHA) on Cognitive Function in Children 4 Years of Age
The primary objective of this study is to determine whether a 4-month period of supplementation with 400 mg/day of docosahexaenoic acid (DHA) provided from chewable softgel capsules containing bubblegum flavored microalgal oil…
- Trial name
- NCT00351624
- Testing
- DHA
- Where
- 10 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Eating Behavior, Hunger
Effect of Consumption on Cognitive Processes
To get a better understanding of the interaction between metabolism, neural responses, cognitive processes and appetite the investigaters will examine the effect of food consumption on cognitive processes.
- Conditions
- Eating Behavior, Hunger, Inhibition, Functional Magnetic Resonance Imaging
- Trial name
- NCT03472703
- Testing
- Break-Lunch time
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Endurance Cycling Performance
The Effect of Diet Composition on Performance, Expenditure, Blood Lipids, and Appetite Hormones in Highly Trained Cyclists
This study employs a crossover design to evaluate the effect of two different diets (high carbohydrate vs. ketogenic) and corresponding test meals on endurance exercise performance, energy expenditure including resting metabolic…
- Trial name
- DCAP (NCT04097171)
- Testing
- Diet
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Intracranial Hypertension
Intracranial Pressure and Brain Function: Effects of Head Down Tilt Upon Brain Perfusion and Cognitive Performance
The aim of the study is to understand the relationship between intracranial pressure regulation, cerebral tissue oxygenation and cognitive functioning.
- Trial name
- IPCog (NCT02976168)
- Testing
- 12° head down tilt
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Cognitive Performance
The Effect of Free Weight Resistance Training and Body Composition on Cognition
This study, titled The Effect of Free Weight Resistance Training (FWRT) on Cognitive Function Explored through Eye Tracking, will be a randomized double-blind clinical trial aimed at evaluating how FWRT influences cognitive…
- Trial name
- NCT06662487
- Testing
- Resistance Training
- Where
- Chile
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Valparaiso
Cognitive Decline, Neurophysiologic Abnormality
Effects of a Food Supplement on Cognitive and Neuropsychological Functioning in Older Adults.
The increase in life expectancy is associated with a gradual aging of the population so creating new needs arising from this new situation.
- Trial name
- NCT03145987
- Testing
- Vitis vinifera extract
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Intellectual Disabilities
Examine the Effects of 24-week Exercise Program on Functional Capacity, Cognitive Capacity, and Quality of Life in Individuals With Intellectual and Developmental Disabilities
Physical inactivity and a sedentary lifestyle are prevalent in the population with intellectual and developmental disabilities, and they do not comply with the World Health Organisation's physical activity guidelines.
- Trial name
- NCT06180304
- Testing
- Exercise training
- Where
- Portugal
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Leiria
Healthy, Cognition
Multivitamin for Health and Cognition
Multiple factors contribute to poor mental and cognitive health including well-balanced nutrition. This research project will aim to establish whether a the multivitamin Vitals+ is more effective in improving markers of health…
- Conditions
- Healthy, Cognition, Health
- Trial name
- Vitals+ (NCT07145658)
- Testing
- multivitamin
- Where
- 2 sites in United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Dr Anthony Hobson
Postoperative Cognitive Dysfunction, Acute Postoperative Pain
Effect of TPVB on Postoperative Pain and Cognitive Function After VATS in Elderly Patients
To investigate the effect of ultrasound-guided thoracic paravertebral nerve block on postoperative acute and chronic pain and cognitive function in elderly patients with thoracoscopic partial lung resection.
- Conditions
- Postoperative Cognitive Dysfunction, Acute Postoperative Pain, Chronic Postsurgical Pain
- Trial name
- NCT05364216
- Testing
- Measurement of cognitive function, Thoracic paravertebral block, The assessment of cognitive function
- Where
- China
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Cognitive Function, Growth
Long-term Effects of Iron and Zinc Supplementation During Infancy on Cognitive Performance and Growth
The hypotheses of this study are: 1. Compared to children who received a placebo, children who received iron or zinc or iron and zinc combined will perform better on cognitive tests and will have better growth status at ages 8 to…
- Trial name
- FeZn_FU (NCT00824304)
- Where
- Thailand
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Placebo - Control, Ketone Monoester
The Effects of Exogenous Ketones on Cognitive Function
The purpose of this study is to evaluate the acute effects of exogenous ketone monoester (KME) supplementation on cognitive function in three groups of adults aged 19-55 years: (1) obese, sedentary individuals; (2) lean…
- Trial name
- NCT07051655
- Testing
- Ketone Monoester (KE)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Anesthesia
The Effect of Propofol or Etomidate on Cognitive Function for 1-3 Years Old Children
Based on China's guangxi guilin for a hernia operation in 1 to 3 years old preschool children propofol and etomidate on behavioral and cognitive function after intravenous anesthesia in according to beta protein in serum and…
- Trial name
- NCT02199990
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Guilin Medical University, China
Young Healthy Adults
Effect of High-Intensity Interval Training Exercise on Cognitive Function of Young Adults
To explore the sustainability of the acute effect of High Intensity Interval Training (HIIT) on executive function in young adults.
- Trial name
- NCT06621550
- Testing
- High Intensity Interval Training
- Where
- Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Gestational Diabetes
The Effect of Circuit Exercise Program in Gestational Diabetes
Gestational diabetes (GDM) is defined as 'pregnancy-onset or first noticed glucose intolerance'. The aim of this study is to investigate the effect of circuit exercise program applied in addition to diet therapy on cognitive…
- Trial name
- NCT05096078
- Testing
- Diet, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Nutritional Supplementation
Nutrition21 Study 1
The purpose of this study is to determine the effects of nooLVL containing arginine and inositol supplementation on executive function and memory prior to and following playing video games.
- Trial name
- N21-1 (NCT04828278)
- Testing
- Arginine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Healthy, Brain Stimulation
Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults
The objective of this randomized, double-blind, sham-controlled, crossover study is to evaluate the effects of transcranial electrical stimulation (tES) on complex cognitive task performance in healthy adult volunteers.
- Conditions
- Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition
- Trial name
- BRAIN-STIM (NCT06995560)
- Testing
- Active Transcranial Electrical Stimulation
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital