Clinical trials: Cognitive/Functional Effects
Older Adults
Impact of Respiratory Muscle Training on Cognition in Older Adults
The increase in chronic diseases associated with aging leads to various physical limitations in older adults, negatively impacting fall risk, hospitalization rates, and overall mortality.
- Trial name
- NCT07728279
- Testing
- Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Cognitive Function, E-sports Performance
Visual Training Effects in Esports Players
This randomized controlled study aims to investigate the acute effects of a single session of web-based visual training on balance, reaction time, and cognitive function in professional e-sports players.
- Conditions
- Cognitive Function, E-sports Performance, Reaction Time, Balance
- Trial name
- NCT07570693
- Testing
- Web-Based Visual Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Cognitive Function
Investigation of Acute Mood and Cognitive Performance Effects of Beverages Containing Phenolics in Healthy Adults
An acute, randomized, placebo controlled, double blinded crossover study in health subjects. Participants will complete 4 intervention arms in random order consisting of a placebo control beverage, a high dose phenolic beverage…
- Trial name
- NCT02675621
- Testing
- Phenolic Beverage
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
EEG Brain Oscillations, Alzheimer's Disease (AD)
Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults
This study aims to evaluate the effects of endogenous gamma non-flickering light stimulation on resting-state EEG rhythms and cognitive function in cognitively healthy older adults.
- Conditions
- EEG Brain Oscillations, Alzheimer's Disease (AD), Cognitively Normal Older Adults
- Trial name
- NCT06715995
- Testing
- Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Aging
Pomegranate Extract and Inflammageing
The growing ageing population has resulted in an increase in the prevalence of frailty, cognitive disorders and cardiovascular diseases, representing a major cause of disability in older adults.
- Trial name
- NCT05588479
- Testing
- Pomegranate extract, Control
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Cognitive Function, Mood Disorders
RCT on the Neurobehavioral Effects of Fruits and Vegetables in Shanghai Children
This project proposal outlines a randomized-controlled trial (RCT) aimed at evaluating the effects of increased fruit and vegetable (F\&V) intake on cognitive performance, attention, and mood in Chinese children aged 7-11…
- Conditions
- Cognitive Function, Mood Disorders, Attention-deficit
- Trial name
- NCT06560359
- Testing
- F&V, No F&V
- Where
- China
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Fudan University
Mental Health Wellness 1, Work Related Stress
Mental Balance Study
The proposed design is a randomised, double-blind, controlled, crossover intervention assessing the effects of an active intervention, containing Scutellaria baicalensis and Crataegus, versus placebo, on stress, cognition, sleep…
- Trial name
- NCT05757050
- Testing
- Re-Focus "Verum" Tablets
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
Muscular Strength
The Effects of a 12-week Block Periodization vs. Daily Undulating Periodization on Muscular Strength and Cognitive Function in Healthy Young Adults.
This study compared the effects of two resistance training periodization models, block periodization and daily undulating periodization, on muscular strength and force production in healthy young adults with limited resistance…
- Trial name
- NCT07860151
- Testing
- Block Periodization Resistance Training, Daily Undulating Periodization Resistance Training
- Where
- Poland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Healthy
Creatine Supplementation on Cognition in Children
Creatine supplementation may improve cognitive function in elderly and vegetarian individuals. This study aims to investigate the role of creatine supplementation on cognitive function in healthy children.
- Trial name
- NCT01803230
- Testing
- creatine supplementation
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cognition, Muscle Strength
Dietary Supplements and Middle Aged Women (Creatine)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Muscle Strength, Fatigue Symptom, Blood Pressure and Augmentation Index
- Trial name
- NCT07729930
- Testing
- Creatine Monohydrate
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Glucose Metabolism, Glucagon
Investigating the Acute Effects of Increasing Glucagon Exposure in Healthy Participants
In this study the investigators will investigate the acute effects of increasing glucagon exposure on metabolic parameters in healthy participants. Participants will participate in one study day.
- Trial name
- NCT06921824
- Testing
- Glucagon
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Nicolai Jacob Wewer Albrechtsen
Cognitive Function and Mood, Cerebral Blood Flow
The Effects of Resveratrol Supplementation on Cognition, Cerebral Blood Flow, Microbiota and Systemic Inflammation.
Previous research shows that a diet high in fat has harmful effects on gut health. This increases the chance of developing obesity-related diseases (such as type 2 diabetes) and disrupts cognition and mood.
- Conditions
- Cognitive Function and Mood, Cerebral Blood Flow, Systemic Inflammation, Gut Microbiota
- Trial name
- NCT03448094
- Testing
- Resveratrol
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy
A Study of the Effect of Daridorexant on Nighttime Body Posture, the Noise Level Required to Wake up, and the Ability to Remember Words Previously Presented
A Study of the Effect of Daridorexant on Nighttime Body Posture, the Noise Level Required to Wake up, and the Ability to Remember Words Previously Presented
- Trial name
- NCT05702177
- Testing
- Daridorexant 25 mg, Daridorexant 50 mg
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Cognitive Function and Mood
Investigation of the Acute Calming Effects of Drinks Containing Herbal Extracts in Healthy Adults
The primary objectives of this study are to assess the effects of three investigational drinks containing three botanicals in differing combinations versus a placebo control, on mood, psychological state, physical response, and…
- Trial name
- NCT02675582
- Testing
- Herbal Beverage
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Cognitive Ability, General
Nutrigenomics, PUFA, Iron and Cognition Amongst Under-two-year-old Indonesian Children
Rationale: Review on the positive effect of long chain polyunsaturated fatty acids (LCPUFA), especially docosahexanoic acid (DHA), supplementation on cognitive function in human using randomized controlled trials (RCTs) showed…
- Trial name
- NUPICO (NCT01504633)
- Testing
- DHA/EPA and iron supplementation
- Where
- Indonesia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Microbiota, Cognitive Function
Effect of Tomato Paste Consumption on the Microbiota-gut-brain Axis in Healthy Adults
Tomatoes and tomato-based products could play an important role in modulating microbiota-gut-brain axis (MGBA) interactions due to their high content of fiber and phytochemicals.
- Conditions
- Microbiota, Cognitive Function, Healthy Lifestyle
- Trial name
- MITOS (NCT05891977)
- Testing
- Intervention A - Tomato paste, Intervention B - Control
- Where
- Spain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Sleep, Emotion
The Effects of Acute vs. Chronic of Screen Illumination on: Sleep Efficacy and Architecture, Physiology, Emotion and Behavior: Possible Effect on Human Health
The human eye has a dual role, which is reflected by the various photo-receptors used for vision of images and colors ,Image forming photoreceptors (IFP) and for entrainment of our "Biological clock" located in the hypothalamus…
- Trial name
- NCT02839395
- Testing
- No intervention- base line, Acute, Chronic
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
Healthy Volunteers (HV)
Examining the Effects of Reformer Pilates Exercises on Physical Fitness and Cognitive Functions in Healthy Individuals
Pilates is an exercise method that aims to increase body awareness and improve physical fitness through controlled movements based on mind-body integration.
- Trial name
- NCT07134517
- Testing
- Pilates exercise
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Inonu University
Cognition
Effects of Hyperbaric Oxygen Therapy on Cognitive Function on Autistic Spectrum Disordered Children
HYPOTHESIS 1. Hyperbaric Oxygenation Therapy will be safe to use with neurotypical adults and children. 2. Hyperbaric Oxygenation Therapy will have a statistically significant positive effect on measures of cognitive function in…
- Trial name
- NCT00631215
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pediatric Partners of Ponte Vedra
Presbyopia
The Effects of Glasses-Free 3D Training on Visual and Cognitive Function in Presbyopic Individuals
This study aims to evaluate the effectiveness of glasses-free 3D visual training in improving visual function, visual comfort, and the application ability of visual functions in individuals with presbyopia.
- Trial name
- NCT06853691
- Testing
- glasses-free 3D visual training
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University