Clinical trials: Cognitive/Functional Effects
Alteration of Cognitive Function
The Effect of Breakfast Size Prior to Morning Exercise on Cognition, Mood and Appetite in Habitually Active Women
Both regular exercise and breakfast consumption have well known health benefits. Consuming breakfast prior to morning exercise may influence appetite, mood and cognitive function later in the day.
- Trial name
- NCT01711008
- Testing
- Cereal, No breakfast
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Young Healthy Adults
Effect of High-Intensity Interval Training Exercise on Cognitive Function of Young Adults
To explore the sustainability of the acute effect of High Intensity Interval Training (HIIT) on executive function in young adults.
- Trial name
- NCT06621550
- Testing
- High Intensity Interval Training
- Where
- Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Turner's Syndrome
Effect of Estrogen on Mental and Social Functioning in Girls With Turner's Syndrome
RATIONALE: Turner's syndrome is a disease in which females are missing all or part of one X chromosome and do not produce estrogen. Giving estrogen is standard treatment for girls who have Turner's syndrome.
- Trial name
- NCT00004274
- Testing
- Estrogen
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tobacco Use Disorder, Nicotine Dependence, Cigarettes
Effects of Nicotine Dependence on Multidimensional Health Outcomes
Nicotine, a major toxic component of cigarette smoke, together with carbon monoxide (CO), constitutes a significant environmental exposure with systemic effects.
- Trial name
- NCT07474623
- Testing
- Comprehensive Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Bipolar Disorder, Cognitive Impairment
Effects of Erythropoietin on Cognition and Neural Activity in Mood Disorders
The present trial consists of 2 sub-studies that investigate important novel aspects of treatment with erythropoietin (EPO) on cognitive dysfunction in bipolar disorder (BD) and recurrent unipolar depressive disorder (UD)…
- Conditions
- Bipolar Disorder, Cognitive Impairment, Unipolar Depression
- Trial name
- PreTEC-EPO (NCT03315897)
- Testing
- Erythropoietin, Saline
- Where
- Denmark
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Lars Vedel Kessing
Cognitive Ability, General
Cybercycling for Cognitive Health
Exercise has been linked to cognitive health, but few older adults exercise at recommended levels. Cybercycling may provide additional cognitive benefits due to increased motivation to ride the interactive 3D tours.
- Trial name
- NCT01167400
- Testing
- Cybercycling, Traditional exercise
- Where
- 8 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Union College, New York
Hypogonadism, Gender Identity Dysphoria
The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgender Active-Duty Population
It has been known that both estrogen and testosterone are the major sex steroids regulating bone metabolism and other physiological changes in both male and female, respectively.
- Trial name
- NCT06247267
- Testing
- Fortesta, Estradiol
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Healthy
Creatine Supplementation on Cognition in Children
Creatine supplementation may improve cognitive function in elderly and vegetarian individuals. This study aims to investigate the role of creatine supplementation on cognitive function in healthy children.
- Trial name
- NCT01803230
- Testing
- creatine supplementation
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Psychosis
Investigating the Effect of a Single-dose of Levetiracetam on Brain Function, Chemistry and Cognitive Performance in Psychosis Risk
Background Psychosis is a mental health condition that affects around 3 in 100 people in their lifetime. Most treatments for psychosis target a brain chemical called dopamine but they don't work for everyone and don't address…
- Trial name
- LEVHIPPRO (NCT06224530)
- Testing
- Levetiracetam
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- King's College London
Mental Competency, Urinary Bladder, Overactive
The Effect of Anticholinergics on Cognitive Function in the Elderly
Anticholinergic medication is used to treat overactive bladder (OAB). A known side effect of this medication is cognitive dysfunction.
- Conditions
- Mental Competency, Urinary Bladder, Overactive, Cognitive Function
- Trial name
- ACE (NCT01922115)
- Testing
- Trospium Chloride
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cognitive Dysfunction
Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ)
Deterioration of posoperative cognitive function (DCPO) is an intermediate state between normal cognitive aging and dementia, defined as a cognitive alteration greater than expected for the patient's age and educational level…
- Trial name
- ketaminvsMDZ (NCT04134052)
- Testing
- ketamine sedation versus midazolam sedation
- Where
- Mexico
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad de Colima
Cerebral Glucose Metabolism
Development of a Non-invasive Method for Quantifying Cerebral Glucose Metabolism for Studying the Effect of Glucagon in Humans
The aim of the study is to develop a non-invasive method for quantifying cerebral glucose metabolism by PET scans in humans. This method will be used in subsequent studies, where the effect of the pancreatic hormone glucagon on…
- Trial name
- NCT06647368
- Testing
- PET with 18-FDG
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Nicolai Jacob Wewer Albrechtsen
Brain Aging
AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults
The goal of this clinical trial is to determine if adding avocados to the diet of impacts cognition in 70 older adults, age 65-85, without dementia.
- Trial name
- AvoCog (NCT06137339)
- Testing
- Avocado Group
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Glucose Metabolism, Glucagon
Investigating the Acute Effects of Increasing Alanine Exposure in Healthy Participants
In this study the investigators will investigate the acute effects of increasing alanine exposure on metabolic parameters in healthy participants. Participants will participate in one study day.
- Trial name
- NCT07350512
- Testing
- alanine
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nicolai Jacob Wewer Albrechtsen
Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease, Heroin Addicts
Effect of Exercise on Cognitive Function and Mental Health in Heroin Addicts
The goal of this [type of study: exercise intervention study] is to test in describe participant health conditions. The main questions it aims to answer are: [Whether physical exercise improves executive function of male heroin…
- Conditions
- Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease, Heroin Addicts, Executive Function, Negative Thinking/Affect
- Trial name
- NCT05650983
- Testing
- Aerobic exercise; Resistance exercise
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangzhou Sport University
Bipolar Disorder, Cognitive Impairment
Effect of Action-Based Cognitive Remediation in Patients With Bipolar Disorder
PRETEC-ABC aims to assess the effect of a new form of cognitive remediation, Action-Based Cognitive Remediation (ABCR), in patients with bipolar disorder in remission on cognition, and to assess the neural assays for treatment…
- Trial name
- PRETEC-ABC (NCT03295305)
- Testing
- Action-Based Cognitive Remediation, Unstructured support group
- Where
- Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Aging
Effect of mTOR Inhibition & Other Metabolism Modulating Interventions on the Elderly [SubStudy Rapa & cMRI to Evaluate Cardiac Function]
The ability to mount an effective immune response declines with age, leaving the elderly increasingly susceptible to infectious diseases and cancer.
- Trial name
- mTOR (NCT04742777)
- Testing
- rapamycin
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Cognitive Function 1, Social, Cognitive Change
GReen And Healthy Schools
This project aims to investigate the health effects of making schools greener and more biodiverse. We will mainly focus on cognitive effects, well-being, and BMI.
- Conditions
- Cognitive Function 1, Social, Cognitive Change, Emotions, Weight, Body
- Trial name
- GRAS (NCT04898439)
- Testing
- greening of the school environment
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Creatine Supplementation, Exercise Ergogenics
Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men
This study evaluates whether 7-day creatine monohydrate supplementation affects cognitive function after high-intensity interval training (HIIT) in active young men.
- Trial name
- HIITCRECOG (NCT07534293)
- Testing
- Creatine Monohydrate, High Intensity Interval Training
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitas Negeri Malang
Old Age; Debility
Puzzle Game Strategy on Older Adults
One innovative approach uses puzzle game strategies, including crosswords, Sudoku, and other brain-teasing activities. These strategies have been shown to help maintain attention, improve memory, and keep older adults' thoughts…
- Trial name
- PUZZLEOLDER (NCT06459492)
- Testing
- puzzle game strategies
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alexandria University