Clinical trials: Cognitive Aids
Cognition, Gut Microbiome
The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study
This project uses a hybrid trial design to evaluate two biomedical interventions targeting the gut-brain axis. One intervention is portable Transcutaneous Vagus Nerve Stimulator, tVNS, that is hypothesized to stimulate the…
- Trial name
- NCT05090267
- Testing
- Probiotic Supplement, Transcutaneous Vagal Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Florida
HIV - Human Immunodeficiency Virus, Cognitive Impairment
Cognitive Training for the Remediation of Functional Brain Health in HIV
Cognitive deficits in HIV reflect degraded brain network functioning that may be amenable to remediation through cognitive training.
- Trial name
- NCT02571504
- Testing
- Plasticity-based Adaptive Cognitive Remediation (PACR)
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- McGill University
Depression, Medication Adherence
Cognitive Behavioral Therapy on Adherence and Depression (CBT-AD) Among HIV/AIDS Patients
Depression is highly comorbid with HIV/ AIDS and is associated with worse poor adherence to antiretroviral therapy (ART), and potentially to long-term immune functioning. Cognitive behavioral therapy may solve these problem.
- Trial name
- NCT06109610
- Testing
- Cognitive Behavioral Therapy
- Where
- Ethiopia
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Mattu University
Depression, HIV
Depression Therapy to Improve Cardiovascular Risk in HIV
This trial will determine if depression treatment will reduce cardiovascular risk in HIV-infected patients already receiving HIV treatments.
- Trial name
- NCT02309372
- Testing
- Beating the Blues
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Indiana University
Cognitive Aids
Effect of an Electronic Cognitive Aid Versus Static Cognitive Aid on the Management of a Simulated Crisis
Clinical decision support tools with in the electronic medical record can improve clinical care processes. To date, there is little evidence evaluating crisis management with such decision support tools.
- Trial name
- NCT02440607
- Testing
- Electronic Cognitive Aid, Static Cognitive Aid
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Endeavor Health
Human Immunodeficiency Virus Infection (HIV), Sexually Transmitted Disease (STD)
Being Responsible for Ourselves HIV Risk Reduction for Black MSM
The incidence of HIV/AIDS among African American men who have sex with men (MSM) is alarming, and the public health response to this urgent situation has been hampered by a lack of sexual risk reduction interventions with solid…
- Trial name
- BRO (NCT02561286)
- Testing
- BRO HIV Risk Reduction Intervention, Health Promotion Intervention
- Where
- United States
- Volunteers
- 595 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
HIV Infections, Adverse Effects
Trial of Cognitive Behavioral Therapy to Reduce Antiretroviral Therapy Side Effects
The hypothesis is that participants in the intervention group will experience fewer/less intense side effects from anti-HIV medications, if they receive training sessions on the use of guided imagery, relaxation, and reframing of…
- Trial name
- NCT00696839
- Testing
- Cognitive-behavioral therapy
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Duquesne University
Human Immunodeficiency Virus
Cognitive-Based Compassion Training (CBCT) for People Living With HIV (PLHIV)
The purpose of the study is to examine the effects of cognitive-based compassion training (CBCT), a meditative practice based on Buddhist teachings, on long term emotional well-being and immune system improvement with people…
- Trial name
- NCT02395289
- Testing
- Cognitive-Based Compassion Training (CBCT), Health discussion
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Emory University
HIV/AIDS, Cognitive Impairment
A Randomized Pilot Trial Evaluating the Impact of a Yoga Intervention on Cognition in Older Adults Infected With HIV
Approximately 50% of people living with HIV (and as many as 80% over the age of 50) have difficulties with cognitive functions such as memory and thinking that can have a profound negative impact on activities of daily living and…
- Conditions
- HIV/AIDS, Cognitive Impairment, Aging, Mobility Limitation
- Trial name
- NCT03071562
- Testing
- Yoga-mindfulness
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Adria Quigley
HIV Infections
Computerized Cognitive Rehabilitation in Ugandan Children With HIV
One-hundred and fifty-nine school-age children with HIV in Kayunga District, Uganda were randomized to one of 3 treatment arms: 24 training sessions of a computerized cognitive rehabilitation therapy (CCRT) program called…
- Trial name
- NCT00926003
- Testing
- Full Computerized cognitive training, Limited computerized cognitive training
- Where
- Uganda
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Inappropriate Prescribing
The Study in Outpatient Medicine Using Nudges to Improve Sleep
The goal of this clinical trial is to learn if electronic health record (EHR) nudges (changes to the EHR that do not restrict freedom of choice or alter incentives) can reduce Z-drug prescribing in primary care clinics for…
- Trial name
- SOMNUS (NCT06640023)
- Testing
- Z-drug Default Quantity, Redirection + Accountable Justification
- Where
- United States
- Volunteers
- 444 people
- Sponsor
- University of Southern California
HIV/AIDS, Aging
Psychosocial Intervention for Older HIV+ Adults With HAND
CTNPT 029 will test the feasibility and acceptability of cognitive remediation group therapy in older adults living with HIV who have been diagnosed with HIV-associated neurocognitive disorder (HAND).
- Conditions
- HIV/AIDS, Aging, Mild Cognitive Impairment, Group, Peer
- Trial name
- IN-HAND (NCT03483740)
- Testing
- CRGT, HIV group therapy
- Where
- 3 sites in Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Cognitive Aids
Use of a Wearable Digital Cognitive Aid in Simulated Anesthesia and Intensive Care Crises.
The purpose of this study is to determine whether a wearable digital cognitive aid has an effect in the management of simulated crises in anesthesia or intensive care.
- Trial name
- SIMMAX (NCT02678819)
- Testing
- Digital cognitive aid
- Where
- France
- Volunteers
- 52 people
- Sponsor
- CEJKA Jean-Christophe
Insomnia, HIV
A Pragmatic Pilot Study of Cognitive Behavioural Therapy for Insomnia Among People Living With HIV
Insomnia is a problem for approximately 75% of people living with HIV, which is much higher than the 6% to 10% of people with insomnia in the general population.
- Trial name
- NCT02887209
- Testing
- CBT-I
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Toronto Metropolitan University
HIV/AIDS, Drug Abuse
Cognitive Behavioral Stress Management for HIV+ Drug Abusers
The primary purpose of this 5-year study is to determine whether a Cognitive Behavioral Stress Management (CBSM) intervention, demonstrated to be effective in reducing distress, enhancing coping, and maintaining health among HIV+…
- Conditions
- HIV/AIDS, Drug Abuse, Alcohol Abuse
- Trial name
- NCT00722644
- Testing
- Cognitive Behavioral Stress Management
- Volunteers
- 450 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Methamphetamine Abuse, HIV/AIDS
FASTLANE II: Reducing Sex, Drug, and Mental Health Risk
The study uses a repeated measures, single group pretest-posttest design methodology to examine the feasibility, acceptability, and preliminary effectiveness of the FASTLANE II intervention aimed at decreasing risky sex behaviors…
- Conditions
- Methamphetamine Abuse, HIV/AIDS, Depression, Sex, Unsafe
- Trial name
- FLII (NCT04109014)
- Testing
- FASTLANE II
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cognitive Disorders, HIV Infections
A Study of Decreased Mental Function Associated With HIV
The purpose of this study is to compare pictures of the brain of HIV-infected people with memory problems before and after treatment with selegiline. Selegiline is the study drug received through A5090.
- Trial name
- NCT00027040
- Testing
- Selegiline hydrochloride
- Where
- 12 sites in United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV - Human Immunodeficiency Virus, Insomnia Disorder
A Sleep Program to Improve Sleep Quality in People With HIV
Sleep problems, such as insomnia, are more frequent and intense in individuals living with HIV. These sleep difficulties can increase the difficulties in thinking and concentrating.
- Trial name
- NCT02571595
- Testing
- Digital cognitive behavioural therapy for insomnia (dCBT-I)
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- McGill University
HIV, Arterial Stiffness
High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV
This is a single site, randomized exercise trial with individuals at least 50 years of age living with HIV who experience suboptimal cognition.
- Conditions
- HIV, Arterial Stiffness, Cognitive Dysfunction
- Trial name
- NCT05965518
- Testing
- High-Intensity Interval Training, Continuous Moderate Exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Depression, HIV Infection
Cognitive Behavioral Therapy to Help HIV Infected Adults With Depression to Adhere to Antiretroviral Therapy
This study will compare the effectiveness of a cognitive behavioral intervention versus usual clinic care in helping HIV infected adults with depression to take their HIV medications on schedule.
- Trial name
- NCT00509340
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- RAND