Clinical trials: Cognitive Change, open to volunteers
Addiction;Drug(S);LSD, Neuroprotective
Neuroprotective Effect of (Nano PSO), in Patients Who Used to Consume Psychoactive Substances
Addiction problems to psychoactive substances are becoming more frequent, which implies a serious health problem, with social, family and work repercussions.
- Trial name
- NCT06550167
- Testing
- Nano-PSO, Pomegranate seed oil (omega-5)
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Distribuidora Biolife SA de CV
Cognitive Impairment, Cognitive Change
Early Cognitive Interventions in Digital Format for Cancer Survivors
The aim of this study is to evaluate the usability and effectiveness of two professionally supervised home-based cognitive training interventions as part of an early rehabilitation protocol for cancer-related cognitive…
- Conditions
- Cognitive Impairment, Cognitive Change, Cancer
- Trial name
- INCOTEM (NCT07729969)
- Testing
- Computerized cognitive treatment, Virtual reality cognitive training
- Where
- 3 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Biogipuzkoa Health Research Institute
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cognitive Change, Well-Being, Psychological
Trout Consumption in Young Children and Families and Brain Health
Regular fish consumption may support brain health. Trout lines developed in Idaho contain higher levels of omega-3 fatty acids, nutrients important for human cognition and mental wellbeing.
- Trial name
- NCT06721468
- Testing
- Trout, Child-centered nutrition phrases, Puzzle
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Idaho
Aging, Cognitive Change
Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging
Much of human interaction is based on trust. Aging has been associated with deficits in trust-related decision making, likely further exacerbated in age-associated neurodegenerative disease (Alzheimer's disease/AD), possibly…
- Conditions
- Aging, Cognitive Change, Neurocognitive Disorders, Mild
- Trial name
- DecidingBrain (NCT05457725)
- Testing
- Contingent rtfMRI neurofeedback training
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Florida
COPD, Physical Activity
Effects of Adapted Snacktivity™ Intervention on Cognition and Self-Care in COPD Patients
This clinical trial aims to evaluate whether a culturally adapted Snacktivity™ program can improve cognitive function and self-care abilities in patients with Chronic Obstructive Pulmonary Disease (COPD) in Hong Kong.
- Conditions
- COPD, Physical Activity, Cognition, Self Care
- Trial name
- Snacktivity™ (NCT07702994)
- Testing
- Snacktivity™ Intervention, attention control
- Volunteers
- 210 people
- Sponsor
- The University of Hong Kong
Obstructive Sleep Apnea, Sleep Disorder
Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy
This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy.
- Conditions
- Obstructive Sleep Apnea, Sleep Disorder, Well-Being, Psychological, Cognitive Impairment
- Trial name
- MULTI-OSAS (NCT06312956)
- Testing
- Continuous Positive Airway Pressure Ventilotherapy
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Istituto Auxologico Italiano
Heat Stress, Physiological Stress
Heat Stress in Individuals With Schizophrenia
Schizophrenia is a severe mental illness affecting approximately 24 million people worldwide and is associated with more than double the all cause mortality risk of the general population.
- Conditions
- Heat Stress, Physiological Stress, Cognitive Change
- Trial name
- NCT07383324
- Testing
- Simulated exposure to indoor overheating
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Ottawa
Psychological Adaptation, Cognitive Change
Health Psychological Group Rehabilitation for Patients With Chronic Fatigue Syndrome (ME/CFS)
Chronic fatigue syndrome (ME/CFS) is a severe medical condition. It is characterized by long term fatique and other persisted symptoms, such as a cognitive disabilities and orthostatic intolerance.
- Conditions
- Psychological Adaptation, Cognitive Change, Adaptive Behavior, Functioning
- Trial name
- NCT04151693
- Testing
- Health Psychological Group Rehabilitation for Patients With Chronic Fatigue Syndrome (ME/CFS)
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Postoperative Neurocognitive Disorders
Validation of the Modified Cognitive Assessment Scale (MoCA Blind) for the Diagnosis of Postoperative Neurocognitive Disorders in Patients With Corneal Pathology in Russia.
Long-term observation has shown that patients with visual impairment often develop cognitive impairments. Due to the fact that patients who are planning to undergo corneal transplantation may have initial cognitive deficits…
- Trial name
- NCT07423416
- Testing
- Neurocognitive testing
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Brain Tumor, Pediatric
Measuring Brain Changes Following Cognitive Intervention in Pediatric Patients With Brain Tumors
The goal of this study is to learn if an online computerized training program improves processing speed, attention, and working memory in children with a primary brain tumor during and after active cancer treatment.
- Trial name
- NCT07558473
- Testing
- Online computerized cognitive training intervention focused on processing speed.
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Aging, Brain Metabolic Disorder
Monitoring of Brain Metabolites Using Proton and Deuterium MR Techniques
MR pulse for whole brain optimal Deuterium (2H) Metabolic Imaging and EPSI (echo planar spectroscopic imaging) based SLOW-edited 1H-MRSI will be developed and optimized for use at an UHF scanner at 7 Tesla.
- Conditions
- Aging, Brain Metabolic Disorder, Carotid Stenosis, Alzheimer Disease
- Trial name
- SIGNATURES2023 (NCT06705010)
- Testing
- Application of new pulse sequence package SIGNATURES2023 to healthy controls, Application of new pulse sequence package SIGNATURES2023 to 4 groups of patients (pilot)
- Where
- Switzerland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Post Traumatic Stress Disorder
Cognitive Processing Therapy for Posttraumatic Stress Disorder and Co-occurring Lived Experience Stress
Populations facing health disparities include groups with significantly higher rates of posttraumatic stress disorder than the general population who frequently experience lived experience stress, which may complicate…
- Trial name
- NCT07714083
- Testing
- Standard CPT, CPT-LEAP
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Boston University
Aerobic Exercise, Cognitive Change
The Role of the Time of Day in the Effects of Exercise on Memory in Heathy Young Adults
Cumulative evidence indicates that a single bout of exercise has beneficial impacts on memory in young adults. From a physiological perspective, acute exercise leads to changes of heart rate variability (HRV), which is associated…
- Trial name
- TEEMY (NCT04861818)
- Testing
- Moderate-intensity aerobic exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Proportional Reasoning
Modifying Cognitive Strategies for Comparing Proportions
The goal of this study is to understand the cognitive processes underlying quantitative and relational reasoning, including the understanding of mathematical information (e.g., numbers, proportions, percentages, geometry) and…
- Trial name
- NCT06635577
- Testing
- Verbal Interference Task
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Michelle Hurst, PhD
Alzheimer Disease, Aging
Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness
The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau…
- Conditions
- Alzheimer Disease, Aging, Lifestyle Factors, Cognitive Impairment
- Trial name
- LIBRA REMIND (NCT07042087)
- Testing
- Mindfulness Yoga, Time-Restricted Eating with nutritional counseling promoting a flexitarian dietary pattern, Cognitive Training
- Where
- Czechia
- Volunteers
- 48 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Chronic Pain, Depression
Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study
The goal of this clinical trial is to pilot a randomized controlled trial comparing an adaptation of mindfulness-based cognitive therapy to the health enhancement program for chronic pain and depression.
- Trial name
- NCT07118722
- Testing
- Quiet Focus, Health Enhancement Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Age-related Hearing Loss, Hearing Loss, Sensorineural
A Prospective Cohort Study On Change of Cognitive Function In Aged-related Hearing Loss With Hearing Aids
Background: Deafness is one of the nine potentially modifiable risk factors for dementia simulated by the Lancet dementia Prevention, intervention and Care Committee in 2017.
- Conditions
- Age-related Hearing Loss, Hearing Loss, Sensorineural, Hearing Aid, Cognitive Function Abnormal
- Trial name
- NCT05694039
- Testing
- Hearing Aids
- Where
- China
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OSA - Obstructive Sleep Apnea, Cognitive Functions
Cognitive Function in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder and has been increasingly recognized as a contributor to cognitive decline and a potential risk factor for neurodegeneration.
- Trial name
- CUFM1DN (NCT07364318)
- Where
- Slovakia
- Volunteers
- 30 people
- Sponsor
- Comenius University
Major Depressive Disorder
Multi-site Feasibility of an Integrated Treatment for the Biology and Experience of Depression: The MULTIBED Study
This randomized 2x2 factorial intervention trial administers 8 weekly cognitive behavioral therapy (CBT) sessions (yes/no) and 4 bi-weekly active whole-body hyperthermia (WBH) sessions (yes/no) to adults aged 18 years or older…
- Trial name
- NCT07596914
- Testing
- Cognitive Behavioral Therapy (CBT), Whole-Body Hyperthermia
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco