Clinical trials: Cognitive Communication Disorder
Autism Spectrum Disorder
Social Cognitive Development in Young Children With Autism
Through the development of a novel treatment targeting core Autism Spectrum Disorder (ASD) social deficits and studying the efficacy of this intervention, the investigators hope to provide a means for children with ASD to more…
- Trial name
- NCT01425918
- Testing
- Social Enhancement Intervention, Parent Education
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Mental Health Care, Mental Disorders
Using Responsible Artificial Intelligence (AI) to Predict Online Therapy Outcome and Engagement
This study is to develop AI-based models for the personalised prediction of treatment engagement and treatment outcomes in patients engaging in digital psychotherapy.
- Trial name
- NCT05758285
- Testing
- AI-Based Prediction of Treatment Engagement and Outcomes
- Where
- Switzerland
- Volunteers
- 6,671 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Dementia, Alzheimer Disease
The Swedish BioFINDER 2 Study
The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g.
- Conditions
- Dementia, Alzheimer Disease, Parkinson Disease, Lewy Body Disease
- Trial name
- BioFINDER2 (NCT03174938)
- Testing
- Flutemetamol F18 Injection, [18F]-RO6958948, Elecsys (Roche) Abeta42, Ttau and Ptau
- Where
- 2 sites in Sweden
- Volunteers
- 2,950 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Primary Progressive Aphasia, Dementia
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates positive effects of speech-language treatment for individuals with PPA…
- Conditions
- Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease
- Trial name
- NCT05741853
- Testing
- Video-Implemented Script Training for Aphasia (VISTA), Lexical Retrieval Training (LRT)
- Where
- 3 sites in United States, Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stephanie Grasso
Deafness
Development of a Deaf Child With a Cochlear Implant.
Cochlear implantation enables profoundly deaf children to acquire speech and develop their understanding of spoken language. However, there are significant interindividual differences in the results obtained with the implant.
- Trial name
- DECCODES (NCT02539901)
- Testing
- Evaluation of the detection of non-linguistic sounds, Free hearing test categorization, Early Social Communication Scale (ECSP)
- Where
- France
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Parkinson Disease
tACS Modulates Speech and Cognitive Impairments in People With PD by Targeting the Medial Frontal Cortex
This clinical trial aims to study whether transcranial alternating current stimulation (tACS) applied to the medial frontal cortex (MFC) can improve speech and cognitive function in people with Parkinson's disease (PD), and to…
- Trial name
- NCT07240272
- Testing
- 6Hz-tACS
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ke Dong, MD
Autism Spectrum Disorder, Complication of Prematurity
Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Preterm children are at increased risk for autism spectrum disorders, with an estimated rate of 10%. In the US, about 1 in 8 pregnancies ends with a premature birth.
- Trial name
- ASD-CXCR4 (NCT01686685)
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Impaired Cognition, Geriatric Disorder
The Efficacy of Using Volunteers to Implement a Cognitive Stimulation Program in Two Long-Term Care Homes
Many volunteers visiting seniors make socially-based "friendly visits". This study investigated the efficacy of volunteers making visits focused on stimulating cognition.
- Conditions
- Impaired Cognition, Geriatric Disorder, Learning Disorders, Age-Related Memory Disorders
- Trial name
- VolCogStim (NCT01818778)
- Testing
- Cognitive stimulation program, Standard Friendly Visit
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Queen's University
Epilepsy Syndrome
Cognitive Impairments in Children With Epilepsy
Since the proportion of language and attentional difficulties in patients with epilepsy is recognized, both in the literature and in the clinical experience of practitioners, it is appropriate to propose a complete…
- Trial name
- NCT05097742
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Schizophrenia
Brain Stimulation And Group Therapy to Improve Gesture and Social Skills in Psychosis (BrAGG-SoS)
Randomized, double-blind, placebo-controlled clinical trial testing the effects of 10 sessions of continuous theta burst stimulation and the effects of 16 sessions of social cognitive remediation therapy on gesture performance…
- Trial name
- BrAGG-SoS (NCT04106427)
- Testing
- continuous theta burst stimulation (cTBS), social cognitive remediation therapy (SCRT)
- Where
- Switzerland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Bern
Aphasia
Theory-Driven Treatment of Language and Cognitive Processes in Aphasia
The aim of this research is to translate a theory of the cognitive relationship between verbal short--term memory (STM) and word processing impairments in aphasia to treatment approaches for language impairment in aphasia.
- Trial name
- NCT02664506
- Testing
- Word repetition after a time delay.
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Temple University
Alzheimer Disease, Cognitive Impairment
Negotiation Training for Caregiver Communication in AD
The purpose of this study is to design a Negotiation and Dispute Resolution (NDR) training intervention to improve communication and address resolution of conflicts that family caregivers of patients with cognitive impairment…
- Trial name
- NCT04837937
- Testing
- Caregiver vs. Patient [Beginner], Caregiver vs. Caregiver, Caregiver vs. Physician
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autism Spectrum Disorder, Asperger Syndrome
Effects of a Multimodal Exercise Program for Children With ASD
Exploring the effects of an exercise program for children ages 6 -26 years old who have been diagnosed with autism spectrum disorder and neurotypical children respond to high-intensity whole body exercise interventions (Group 1)…
- Trial name
- NCT05509231
- Testing
- High-intensity exercise, Wearable glove and arm sleeve device to measure movement
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Cognitive Dysfunction, Mild Cognitive Impairment
Cognitive and Physical Home-rehabilitation by Information and Communications Technology. Games for Older Adults Active Life (GOAL)
Aging is often associated with pathological pathway such as in Mild Cognitive Impairment (MCI), and that pathway may be associated to a high risk of dementia.
- Conditions
- Cognitive Dysfunction, Mild Cognitive Impairment, Vascular Cognitive Impairment
- Trial name
- GOAL (NCT03383549)
- Testing
- Tele-rehabilitation
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Perinatal Condition, Neurodevelopmental Disorders
Perinatal and Psychological Correlates of Neurodevelopmental Disorders in Children.
The goal of this observational study is to investigate perinatal, cognitive and social-emotional correlates of neurodevelopmental disorders and educational difficulties in children and adolescents.
- Conditions
- Perinatal Condition, Neurodevelopmental Disorders, Social Functioning, Child Development
- Trial name
- NCT06215092
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Amyotrophic Lateral Sclerosis, Parkinson Disease
A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria
The goal is to improve the fundamental knowledge about articulatory motor performance in people with Lou Gehrig's disease (also known as ALS) and Parkinson's disease (PD), in order to develop more sensitive assessments for…
- Trial name
- NCT03613038
- Testing
- Phonetic complexity effects on speech motor performance
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
ADHD, Dyslexia
Computerized Working Memory Training
Prior research has found that children with attention-deficit hyperactivity disorder (ADHD) and reading difficulties (RD) are at an elevated risk of developing further cognitive deficits and developmental challenges.
- Trial name
- NCT06567444
- Testing
- Working memory intervention
- Where
- Hong Kong
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Right Hemispheric Stroke, Left Hemispheric Stroke
Neural and Cognitive Correlates of Pragmatic Abilities
Pragmatics of language refers to the set of abilities that allow one to use and interpret language according to context and, in general, to communicate effectively.
- Conditions
- Right Hemispheric Stroke, Left Hemispheric Stroke, Traumatic Brain Injury, Right Hemispheric Brain Tumor
- Trial name
- APACS_Neuro (NCT06297044)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Neurodevelopmental Disorders, Developmental Delay
Development of Motility and Cognition in Infants
PILKE study uses wearables for assessing motor development in infants in order to define functional growth trajectories in the normal infants and infants at risk of neurological compromise.
- Conditions
- Neurodevelopmental Disorders, Developmental Delay, Development, Infant, Child Development
- Trial name
- PILKE (NCT05527080)
- Testing
- physiotherapy, brace
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Aphasia, Autism
Transcranial Direct Current Stimulation (tDCS) and Cognitive Processing
This research is being done to determine whether transcranial direct current stimulation (tDCS) can improve certain mental abilities.
- Conditions
- Aphasia, Autism, Schizophrenia
- Trial name
- NCT01602263
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University