Clinical trials: Cognitive Disorder Patients and Cognitive Assessment
Cognitive Disorder Patients and Cognitive Assessment
Study on the Correlation Between Treg Immune Cells on the Muscle Content and Cognitive Functions of the Elderly
In order to explore the impact of the level of the elderly Treg immune cells and the effects of different fat distribution and muscle content, the impact of the level of Treg immune cells on cognitive functions is explored.
- Trial name
- NCT06493669
- Testing
- Cognitive assessment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Stroke
Predicting Cognitive Development in Younger Stroke Patients Using the Oxford Cognitive Screen
The purpose of this study is to investigate whether Oxford Cognitive Screen (OCS) can be used as a predictive tool during hospital admission in younger (<65 years) stroke patients, i.e.
- Trial name
- STROKY (NCT05612815)
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Bispebjerg Hospital
Bipolar Disorder
Physical Exercise for Cognitive Rehabilitation of Patients With Bipolar Affective Disorder
The goal of this clinical trial is to evaluate the impact of Physical Exercise (PE), as an adjuvant treatment, on the cognition of patients diagnosed with Bipolar Disorder who present cognitive impairments, as well as its impact…
- Trial name
- NCT06560749
- Testing
- Physical Exercise
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Beny Lafer
Alzheimer Disease, Telerehabilitation
Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease
Our aim has been determined to investigate the effect of physical exercise alone and in combination with cognitive exercise, on cognitive, physical function and quality of life in individuals with Alzheimer's Disease during the…
- Conditions
- Alzheimer Disease, Telerehabilitation, Online Physical Exercise, Computerized Cognitive Stimulation
- Trial name
- NCT04842734
- Testing
- Physical exercise, Physical exercise and computerized cognitive training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yeditepe University
Core Muscles, Functional Inspiratory Muscle Training
Effect of Functional Inspiratory Muscle Training in Patients with Multiple Sclerosis
This study aims to investigate the effects of functional inspiratory muscle training, basic inspiratory muscle training and physical activity in addition to respiratory exercises on respiratory muscle strength, respiratory…
- Conditions
- Core Muscles, Functional Inspiratory Muscle Training, Multiple Sclerosis, Respiratory Muscles
- Trial name
- NCT06672770
- Testing
- Functional Inspiratory Muscle Training, Basic Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Selcuk University
Vagus Nerve Stimulation, Stroke
Vagal Nerve Stimulation To Enhance Cognition and Learning
The purpose of this study is to find out whether pairing vagus nerve stimulation (VNS) with cognitive training can improve memory and language learning in people who have previously used VNS therapy for movement rehabilitation…
- Conditions
- Vagus Nerve Stimulation, Stroke, Cognitive Assessment, Language Acquisition
- Trial name
- NCT07719387
- Testing
- VNS for Cognition
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stony Brook University
Psychogenic Nonepileptic Seizures, Psilocybin
Evaluation of the Effect of a Single Dose of Psilocybin on Neural Correlates of Cognitive Control in Patients With Psychogenic Nonepileptic Seizures
Psychogenic non-epileptic seizures (PNES) are functional paroxysmal motor disorders that may be clinically suggestive of epilepsy but are not associated with the electroencephysiological and electroencephalographic changes of…
- Trial name
- CRIPSY (NCT06647056)
- Testing
- Psilocybin, MRI
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Anosognosia, Brain Damage
Cognitive-functional Evaluation of Anosognosia
Acquired brain damage patients usually show severe cognitive deficit that alter their performance on every day life activities. Some of them suffer anosognosia and they are not aware of their own limitations.
- Trial name
- NCT03712839
- Testing
- Cognitive-functional evaluation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- María Rodríguez Bailón
Brain Injuries, Brain Diseases
Influence of Physical Exercise on Cognitive Functioning of Traumatic Brain Injury Patients
The aim of this study is to determine the effects of an acute session of physical exercise on cognitive functioning and humor of traumatic brain injury patients and to investigate whether different cognitive responses can be…
- Conditions
- Brain Injuries, Brain Diseases, Central Nervous System Diseases, Craniocerebral Trauma
- Trial name
- NCT01395472
- Testing
- Acute Physical Exercise, Stretching protocol
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cognitive Decline, Cognitive Dysfunction
Open-label, Post-marketing, Prospective Study to Assess Impact of COVID-19 on Cognitive Function in Patients
The objective of this study is to compare the impact of the coronavirus disease (SARS-CoV-2, or COVID-19) on cognitive function in the population of patients who have been diagnosed, treated and recovered from the COVID-19…
- Conditions
- Cognitive Decline, Cognitive Dysfunction, Brain Health, Post CoV-2 Syndrome
- Trial name
- COVID19 (NCT04950673)
- Testing
- Cognivue
- Where
- 4 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cognivue, Inc.
Alzheimer's Disease
Hippocampus Study: Comparative Effect of Donepezil 10mg/d and Placebo on Clinical and Radiological Markers
The purpose of this study is to demonstrate that donepezil slows the progression of Alzheimer's disease (AD) using magnetic resonance imaging (MRI) of the brain to measure the volume of the hippocampus in patients with…
- Trial name
- NCT00403520
- Testing
- Experimental 1
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Eisai Inc.
Malignant Brain Neoplasm
Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy
This phase III trial evaluates whether patient care can be done remotely for patients having cranial (skull) radiation or who have previously had cranial radiation.
- Trial name
- NCT06377696
- Testing
- Best Practice, Medical Device Usage and Evaluation, Metformin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Dementia, Professional-Patient Relations
Intervention to Improve Shared Decision Making Among Seniors With Dementia, Their Caregivers and Healthcare Providers
The increasing prevalence of Alzheimer's disease and other forms of dementia causes new challenges to ensure that healthcare decisions are informed by research evidence and reflect what is important for seniors and their…
- Conditions
- Dementia, Professional-Patient Relations, Professional-Family Relations, Aging
- Trial name
- NCT02956694
- Testing
- Professional e-learning program on shared decision making
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- Anik Giguère
Primary Brain Tumor, Neurocognition
Executive and Socio-cognitive Functions in Survivors of Primary Brain Tumor: Impact on Patients' Quality of Life
Significant advances in primary malignant brain tumors (PBT) treatment have led to dramatically improved survival, both in children and adults.
- Conditions
- Primary Brain Tumor, Neurocognition, Quality of Life
- Trial name
- NEUROCOG-QOL (NCT02693405)
- Testing
- Executive functions, social cognition, quality of life
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Alzheimer's Disease
Efficacy and Safety of Plasma Exchange With 5% Albumin in Beta-amyloid Peptide Clearance in Cerebral Spinal Fluid
The purpose of this study was to evaluate the efficacy and safety of plasma exchange with 5% albumin in beta-amyloid peptide clearance in cerebrospinal fluid, and its effects in patients with mild-moderate Alzheimer's disease.
- Trial name
- NCT00742417
- Testing
- Albutein 5%, Control
- Where
- 4 sites in United States, Spain
- Volunteers
- 42 people
- Sponsor
- Instituto Grifols, S.A.
Fibromyalgia Syndrome, Fibromyalgia
Can a Relaxometer Improve Cognitive Impairment of Fibromyalgia Patients
The aim of the study is to evaluate the differences in cognitive performance and quality of life, after a cycle of treatment with the relaxometer, between a group of patients affected by fibromyalgia and a control group.
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia, Pain, Chronic, Impairment
- Trial name
- Fibrorilax (NCT04170387)
- Testing
- Relaxometer
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Parkinson's Disease (PD), Dual-task
The Effects of Dual Task Training With Different Task Priorities on Physical Performance and Cognitive Status in Patients With Parkinson's Disease
This study was planned to investigate and compare the effects of variable and fixed priority dual task training on balance, walking skills, mobility and cognition in patients with Parkinson's disease.
- Conditions
- Parkinson's Disease (PD), Dual-task, Balance, Walking
- Trial name
- NCT06794177
- Testing
- Variable priority dual task training, Fixed priority dual task training, Single task training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Post-acute Infectious Syndrome (PAIS), Post-COVID-19 Condition (PCC or Long COVID)
Post-acute Infectious Syndrome - Aripiprazole Symptom Evaluation (PAIS-AriSE)
Post-acute infectious syndrome (PAIS), including post-COVID-19 condition (PCC or Long COVID), can develop after an infection and may cause persistent symptoms such as fatigue, problems with memory and concentration ("brain fog")…
- Trial name
- PAISE-AriSE (NCT07714213)
- Testing
- Aripiprazole (low-dose, 1mg)
- Where
- Germany
- Volunteers
- 138 people
- Sponsor
- Christiana Franke
Cognitive Function, Well-Being
Singing Groups for Seniors: Well-Being, Cognitive Function and Health
The researchers' implement and measure the effects of a singing group intervention program for older adults, with an RCT design, in a natural context, on the health, well-being and cognitive function of older adults.
- Conditions
- Cognitive Function, Well-Being, Physical Function, Respiratory Function
- Trial name
- Sing4Health (NCT03985917)
- Testing
- Singing Group Intervention Program, Alternative Social and Leisure Activities
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iolanda Costa Galinha
Intracranial Tumor
Treatment Effects Inclusive Cognitive Impact and Possibilities to Individually Adjusted Treatment in Patients With Intracranial Tumors With Clinical, Neuropsychological and Imaging Parameters
The main purposes with this trial is to investigate the potential of MRI with diffusion and blood volume, flow in brain to diagnose and to measure treatment effects in patients with intracranial tumors, especially gliomas and…
- Trial name
- NCT01674582
- Testing
- MRI, neuropsychological evaluation, blood sampling
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Lund University Hospital