Clinical trials: Cognitive Disorders
Mild Cognitive Impairment
Early Diagnosis of Patients With Mild Cognitive Impairment Through the Parameterization of Functional Tests.
The present study aims to develop an index formed by the variables, functional tests, scales and instruments that best discriminate between healthy subjects and subjects with MCI and that allows the stratification of different…
- Trial name
- NCT03851198
- Testing
- Standard Care or Usual Clinical Practice
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Malaga
Cognitive Dysfunction
Immersive Nature-Based Wellbeing Program in Older Adults With Cognitive Impairment
This study aims to evaluate an immersive virtual reality program designed to support cognitive and emotional well-being in older adults with mild to moderate cognitive impairment.
- Trial name
- COGNITIO (NCT07802392)
- Testing
- Immersive virtual reality program
- Where
- Spain
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Mild Cognitive Impairment, Alzheimer's Disease
The Swedish BioFINDER Study
The present study aims at combining biochemical methods with various types of imaging techniques to identify the pathophysiology of Alzheimer's disease (AD).
- Conditions
- Mild Cognitive Impairment, Alzheimer's Disease, Dementia With Lewy Bodies, Vascular Dementia
- Trial name
- NCT01208675
- Where
- 2 sites in Sweden
- Volunteers
- 1,150 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Creation of an Italian Network of Biobanks of Rare Diseases
ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared Criteria
Rare diseases (RDs) have been defined by the European Union (EU) as life-threatening or chronically debilitating conditions affecting less than 1 person in 2000.
- Trial name
- SATELLITES (NCT06782230)
- Where
- Italy
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Kidney Insufficiency, Chronic
Cognitive Impairment in Kidney Disease
An increasing number of Veterans are anticipated to develop chronic kidney disease (CKD) and require hemodialysis (HD) treatments as the Veteran population ages.
- Trial name
- NCT00905619
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Overweight and Obesity, Inhibition, Psychological
Inhibitory Control Training for Excess Weight: Behavioural, Cognitive and Anthropometric Changes
People with excess weight (EW) are characterized by high impulsivity, high levels of craving for high-calorie foods, deficits in inhibitory control, and maladaptive decision-making.
- Trial name
- InhibeT (NCT06600100)
- Testing
- Inhibitory control training
- Where
- Spain
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Raquel Vilar López
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Metabolic Syndrome, Inflammation
Effects of Berries and Vegetables on Cardiometabolic Risk Markers and Cognitive Functions
The purpose of the study is to study the potential anti-inflammatory- and metabolic effects of polyphenols and dietary fibres in a product based on a mixture of several Swedish berries and vegetables that is known to have high…
- Conditions
- Metabolic Syndrome, Inflammation, Aging, Fermentation
- Trial name
- NCT01562392
- Testing
- berries and vegetables, control product
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lund University
COPD
Novel Vascular Manifestations of Chronic Obstructive Pulmonary Disease
Cognitive impairment is a known consequence of cerebral small-vessel disease. Moderate to severe cognitive impairment has been shown in up to 60% of certain individuals with COPD and is likely to profoundly influence an…
- Trial name
- NOVASC COPD (NCT02060292)
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- North Bristol NHS Trust
Cognitive Decline, Focus Deficit
Effects of Auri Super Mushroom Daily Gummies on Cognitive Health
This is a single-arm, open-label, virtual clinical trial evaluating the cognitive health effects of Auri Super Mushroom Daily Gummies in a population of 35 adult participants over 8 weeks.
- Trial name
- NCT07198399
- Testing
- Auri Super Mushroom Daily Gummies
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Auri Nutrition
Cognition, Affect (Mental Function)
BiomeBakery Project
This study aims to investigate the chronic effects of prebiotic fibre-fortified functional bakery product on cognitive, affective, inflammatory, metabolic, and anthropometric outcomes in healthy adults aged 60-75 years with mild…
- Conditions
- Cognition, Affect (Mental Function), C Reactive Protein
- Trial name
- NCT06796712
- Testing
- Prebiotic fibre fortified bread roll, Regular bread roll
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Reading
Mild Cognitive Impairment Due to Alzheimer's Disease, Subjective Cognitive Decline (SCD)
Autophagy-Enhancers to Reduce Sleep Disturbances
This clinical trial investigates the effects of spermidine supplementation on sleep quality and sleep-dependent memory consolidation in older adults with Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI), two…
- Trial name
- SpSleep (NCT07383311)
- Testing
- Spermidine Supplementation
- Where
- Germany
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Postoperative Cognitive Dysfunction, Mild Cognitive Impairment
Postoperative Cognitive Decline, Inflammation, and Plasma Levels of Beta-amyloids
Postoperative cognitive dysfunction (POCD) can be a serious complication. The development of therapeutic strategies for the prevention and treatment of this condition requires the identification of subgroup of patients with the…
- Trial name
- NCT00850928
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cognitive Function 1, Social
Social Cognition Assessment in Young Adults
The primary objective of this study is to determine the efficacy and feasibility of a battery of neuropsychological measures evaluating social cognition and behavior in young adults diagnosed with schizophrenia, autism spectrum…
- Trial name
- NCT02922400
- Testing
- Social Cognition Assessment and Training
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Pain, Acute, Muscle Tone Abnormalities
Cognitive and Motor Benefits of Standing
Upright-working has been proven to benefit health by combating the negative effects of physical inactivity. However, long-term commitment to static standing regimens may be limited due to symptoms of musculoskeletal fatigue that…
- Conditions
- Pain, Acute, Muscle Tone Abnormalities, Work-Related Condition, Sensory Deficit
- Trial name
- KOGIS (NCT03944564)
- Testing
- Sitting, Static standing, Dynamic standing
- Where
- Slovenia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper
Obesity
Genetic Influences Between Cognitive Function and BMI
In this study the investigators will interrogate an existing data set to examine whether genetic variants contribute to an inverse association between weight status and cognitive function.
- Trial name
- NCT03116334
- Where
- United States
- Volunteers
- 869 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Anxiety
Effect of a Six-week Integrated Attention Training Program on the Cognitive Functions of Older Adults With Co-occurring Anxiety Symptoms and Subjective Cognitive Complaints
The goal of this single-blind randomized control trial is to compare a 6-week Integrated Attention Training Program (IATP) and health education in older people with co-occurrence of anxiety symptoms and subjective cognitive…
- Trial name
- NCT06063265
- Testing
- Integrated Attention Training Program
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Schizophrenia, Depression
Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses
This study will determine the effectiveness of a peer support system in increasing physical activity and effecting health behavior change in people with serious mental illnesses.
- Conditions
- Schizophrenia, Depression, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT00458094
- Testing
- Physical activity intervention with peer support (PA+PS), Physical activity intervention without peer support (PA)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sleep Deprivation
The Effects of Night Call on Intellectual Performance
The purpose of the current proposal will be to examine the clinical performance of both physicians in training as well as experienced faculty in pre and post call situations.
- Trial name
- NCT02697266
- Testing
- No intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Haleh Saadat
Huntington Disease
Innovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease Progression
Intro Huntington's disease (HD) patients suffer from motor, cognitive and behavioral impairments, with heterogeneous phenotypes and variable time course.
- Trial name
- I2BIO-HD (NCT05808153)
- Testing
- radiotracer injection
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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