Clinical trials: Cognitive Function and Well-Being
Patients With Major Depressive Disorder
Cognitive Behavior Therapy Among Patients With Major Depressive Disorder-Multiple Episodes.
The main purpose of this study to teach the patients how to manage their depression, generalized Anxiety symptoms, mental health seeking attitude, motivation and attitude toward changing health, to improve the quality of life…
- Trial name
- NCT07300527
- Testing
- Cognitive Behavior Therapy, treatment as usual (TAU) (Control Group)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Older Adults (65 Years and Older), Fitness Testing
Health-related Physical Fitness and Executive Function in Older Adults: A Prospective Study
This study aims to explore the relationship between health-related physical fitness and behavioural and electrophysiological aspects of cool and hot executive function in older adults through a year prospective study design.
- Conditions
- Older Adults (65 Years and Older), Fitness Testing, Executive Function (Cognition), Prospective Study
- Trial name
- NCT07048561
- Testing
- observation alone
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Muscle Weakness, Bone Health
Healthy Older People Everyday (HOPE) - Role of Healthy Diet on Muscle and Bone Health
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment and falls in older adults carry an increased risk for poor health outcomes and if identified early, can be…
- Conditions
- Muscle Weakness, Bone Health, Cognitive Decline
- Trial name
- HOPE-DIET (NCT03786835)
- Testing
- Protein supplementation and regular physical activity
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Brain Health, Longevity
L-serine and Strength Training in the Elderly
This study investigates whether taking the amino acid L-serine, either alone or in combination with targeted strength training, can have a positive effect on mental performance, brain function, and physical fitness in older…
- Conditions
- Brain Health, Longevity, Cognitive Performance, Strength Training Effects
- Trial name
- AAAging (NCT07466290)
- Testing
- Strength training, L-serine supplementation, Control (cornstarch)
- Where
- Austria
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Menopause, Cognitive Dysfunction
Brain Fog and Life Quality in Menopause
This clinical study aims to investigate cognitive changes in women undergoing the menopausal transition, with a specific focus on the prevalence, characteristics, and impact of brain fog.
- Conditions
- Menopause, Cognitive Dysfunction, Memory Disorders, Quality of Life
- Trial name
- NCT06978218
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Merve Coskun
Cognitive Change
Assessing the Effects of the Muse Meditation System on Cognition and Well-being
Interaxon markets a head-worn EEG biofeedback device ('Muse') to encourage and aid effective meditation and sleep. This device has been previously shown to improve workplace wellness, fatigue and quality of life, and performance…
- Trial name
- MuseCog (NCT04790929)
- Testing
- Muse, Meditation Coaching
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Attention, Memory
The Impact of Supplementation With Hericium Erinaceus (Lion's Mane) Extract on Cognitive Functioning
The goal of this study is to determine whether supplementation with Hericium erinaceus (Lion's Mane) extract enhances selected cognitive functions in healthy, actively working, middle-aged women.
- Conditions
- Attention, Memory, Cognitive Function and Well-Being
- Trial name
- HECOG (NCT07405632)
- Testing
- Hericium erinaceus Supplementation
- Where
- Poland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Mild Cognitive Impairment, Older Adults at High Risk for MCI
The Impact of 6-months of Resistance Training on Brain and Muscle Health in Older Adults With MCI
The goal of this clinical trial is to learn about the effect of long resistance training intervention on brain and muscle health in older adults with mild cognitive impairment (MCI).
- Trial name
- NCT06252844
- Testing
- Resistance exercise training, Active control
- Where
- 2 sites in Lithuania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
Psilocybin Microdosing on Cognition, Mood and Quality of Life
This study is being conducted to evaluate how of 30 days of intermittently microdosed psilocybin affects mood, cognition, subjective well-being and structural/functional MRI results compared to a placebo.
- Trial name
- NCT07449351
- Testing
- Psliocybin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yale University
Mild Cognitive Impairment (MCI), Older People
Digital Health and Exercise for Autonomous Longevity Program
Digital HEAL (Health and Exercise for Autonomous Longevity) is a multicomponent training program (combining concurrent training with cognitive stimulation) designed to promote physical fitness and cognitive function in older…
- Trial name
- DigitalHEAL (NCT06722976)
- Testing
- Multicomponent exercise programs
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Beira Interior
Cognitive Change, Cognitive Impairment
The Everyday Function Intervention Trial
Loss of independence, cognitive decline, and difficulties in everyday function are areas of great concern for older adults and their families.
- Conditions
- Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
- Trial name
- EFIT (NCT04651582)
- Testing
- Cognitive Training, Cognitive Stimulating Activities
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Clemson University
Aging
Breaking Sitting with High-intensity Interval Training for Brain Health
This trial will examine whether interrupting 3.5 hours of sitting every 30 min with 6 min high intensity interval training (HIIT) breaks compared to light intensity interval training (LIIT) will improve brain health in…
- Trial name
- HIIT2SITLess (NCT06243016)
- Testing
- High-Intensity Interval Training (HIIT) Breaks to Sitting, Light-Intensity Interval Training (LIIT) Breaks to Sitting
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Human Immunodeficiency Virus Positive or Negative
Effects of Endocrine Health on Mental Performance of Men and Women Using Drugs
The purpose of this study is to understand the effects of decreased functioning of the testes or ovaries on mental performance in males and females using illicit drugs excluding marijuana.
- Trial name
- NCT00245531
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cognition, Obesity
Nutrition for Brain and Body Health (BB-Health) Feasibility Trial
The goal of the trial is to determine the feasibility of implementing a specific nutrition regimen used alone or in combination with a behavioral weight loss (WL) intervention on cognition and cerebral blood flow in older adults…
- Trial name
- BB-Health (NCT05542199)
- Testing
- Multicomponent nutrition supplement (MCNS), Behavioral weight loss program
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tufts University
Frail Elderly Syndrome
Exercise Mediation on Hormonal, Immune and Psychological Well-being in Institutionalized Frail Older Women.
Frailty syndrome is a complex aging expression determined by ontogenetic and phylogenetic factors. Chronic stress has been shown to have immunosuppressive effects, to accelerate immunosenescence and to cause cumulative disorders…
- Trial name
- UC (NCT04435899)
- Testing
- Physical exercise
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Health Knowledge, Attitudes, Practice
Effect of Endurance Training-Induced Coenzyme Q10 (CoQ10) Supplementation on Myokine, Exerkine Secretion and Cognitive Functions in Long-Distance Runners
The goal of this clinical trial is to learn if CoQ10 amplifies endurance training-induced myokine and exerkine secretion and if those changes influences cognition in long-distance runners.
- Trial name
- NCT06619249
- Testing
- CoQ10 supplementation
- Where
- Poland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Social Isolation in Older Adults, Loneliness
Community-Based Social Connection Intervention Program to Improve Cardiovascular and Brain Health
This study evaluates the effectiveness of a community-based social connection intervention program (SCIP) designed to reduce social isolation and loneliness and improve cardiovascular and brain health among older adults living in…
- Conditions
- Social Isolation in Older Adults, Loneliness, Stroke, Cognitive Decline
- Trial name
- NCT07319663
- Testing
- Social Connection Intervention Program (SCIP): Community activities, peer-support groups, and home-based coaching to reduce social isolation and loneliness.
- Where
- Ecuador
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Healthy, PreDiabetes
Blood Glucose, Cognition and Wellbeing @ Work
This randomized controlled pilot study has as a main aim to investigate the relationship between glucose and cognition and wellbeing, as well as food intake in an at-work setting.
- Trial name
- NCT03295578
- Testing
- Personalized feedback, Generic feedback, Continuous glucose monitoring device
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- TNO
Anxiety Symptoms
Effect of IATP on Cognitive Functioning in Anxious Older Adults.
Older adults with anxiety symptoms was found to be associated with greater risk of dementia. Interventions targeting signs as early as in the pre-symptomatic phase could be most effective in early prevention of dementia.
- Trial name
- NCT04413513
- Testing
- Integrated Attention Training Program (IATP), Health Education
- Where
- Hong Kong
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Mild Cognitive Impairment
WAVE: AudioVisual Stimulation Enhances Cognitive, Mental and Physical Health in Elderly
The goal of this randomized controlled trial is to 1) carry out a screening of cognitive function, depressive symptoms, agility and functional balance and chronic inflammatory conditions in older adults; 2) analyze the influence…
- Trial name
- NCT06686563
- Testing
- Intervention Group: Gamma stimulation, Control Group: Theta stimulation
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Maria Paço