Clinical trials: Cognitive Intervention
Insomnia
Incorporating EMA and EMI Into CBT-I Using mHealth and Wearable Technologies
This study will be a randomised controlled trial to investigate an integrated platform that incorporates ecological momentary assessments/interventions (EMA/I) into cognitive behavioural therapy for insomnia (CBT-I) using mHealth…
- Trial name
- NCT06004869
- Testing
- Ecological momentary assessments/interventions with cognitive behavioural therapy for insomnia (EMA/I CBT-I), Self-help cognitive behavioural therapy for insomnia
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Cognitive Impairment, Memory Complaint
Performance of AclarusDx® a Blood-Based Transcriptomic Test for AD, in French Patients Newly Referred to a Memory Center
The purpose of this study is to assess the performance of AclarusDx™, an investigational blood test detecting gene expression information, and intended to help physicians in making an Alzheimer's Disease diagnosis in patients…
- Conditions
- Cognitive Impairment, Memory Complaint, Clinical Investigation in Memory Centers
- Trial name
- DIALOG (NCT02221661)
- Volunteers
- 606 people
- Sponsor
- Diaxonhit
Emotional Well-being
iCBT to Promote Emotional Well-being in University and Research Communities: Feasibility and Acceptability Study
This study will evaluate a brief internet-based cognitive behavioral therapy (iCBT) program developed specifically for university students, researchers, and academic staff.
- Trial name
- iCBT-Academia (NCT07082296)
- Testing
- iCBT-Academia
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Joaquim Radua
Chronic Migraine, Adverse Childhood Experiences
Effects of Online Mindfulness Therapy on Pain and Stress in Adults With Chronic Migraine and Adverse Childhood Experiences
This study aims to evaluate the effectiveness of an online Mindfulness-Based Cognitive Therapy (MBCT) program in reducing pain, stress-related symptoms, and improving functionality in adults with chronic migraine and a history of…
- Conditions
- Chronic Migraine, Adverse Childhood Experiences, Depression, Anxiety
- Trial name
- NCT07033520
- Testing
- Online Mindfulness-Based Cognitive Therapy
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Fundación Cardiovascular de Colombia
Sexual Distress, Sexual Dysfunctions
Anthesis: A Transdiagnostic Cognitive-Behavioral Therapy (CBT)-Based Approach to Sexual Distress: Testing a Pilot Online Intervention
This pilot study, named Anthesis, evaluates the preliminary efficacy of an online pilot study for sexual distress related to sexual function (SDRSF) in adults.
- Trial name
- Anthesis (NCT06823973)
- Testing
- CBT-based transdiagnostic approach to sexual distress, Waiting list condition
- Where
- 2 sites in Portugal
- Volunteers
- 30 people
- Sponsor
- Grupo Lusófona
Dementia
A Culturally Appropriate Multimodal Non-pharmacological Intervention for Chinese People With Mild-to-Moderate Dementia
This is a mixed-methods research that includes a single-blind three-arms randomized control trials and a focus group study. The quantitative study aims to investigate the additional clinical benefits of the Six Arts intervention…
- Trial name
- NCT03937297
- Testing
- Six Arts, Cognitive Stimulation Therapy (CST), Usual Care
- Where
- Hong Kong
- Volunteers
- 216 people
- Sponsor
- The University of Hong Kong
Anxiety Disorders
Physical Fitness and Brain - Interventional Study
According to the Global Burden of Disease report in 2015, anxiety disorders are among the top 10 contributors to years lived with disability worldwide. There is a need for effective treatment protocols.
- Trial name
- PHYSBI (NCT03247270)
- Testing
- Intervention I, Intervention II
- Where
- Sweden
- Volunteers
- 168 people
- Sponsor
- Göteborg University
Cancer, Fatigue
Health-related Quality of Life-intervention in Survivors of Breast and Other Cancers Experiencing Cancer-related Fatigue Using Traditional Chinese Medicine: The HERBAL Trial
This study is a phase 2, randomized, double-blinded, placebo-controlled trial to evaluate the efficacy and safety of a Traditional Chinese Medicine decoction, the modified Xiang Bei Yang Rong Tang, in alleviating cancer related…
- Conditions
- Cancer, Fatigue, Cognitive Impairment
- Trial name
- HERBAL (NCT04104113)
- Testing
- Modified Xiang Bei Yang Rong Tang
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- National University of Singapore
Cognitive Impairment, Mild Cognitive Impairment
ArtontheBrain: An Inclusive Evidence-based Cognitive Health App for Older Adults to Promote Aging at Home
The research proposed here will evaluate whether a web-based recreation intervention, called ArtontheBrain, has positive health benefits to older adult users.
- Conditions
- Cognitive Impairment, Mild Cognitive Impairment, Dementia, Age-related Cognitive Decline
- Trial name
- NCT03551483
- Testing
- ArtontheBrain, Seniors Online Victoria
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Baycrest
Aging and Cognitive Health, Healty
PotenziaMente: A Digital Executive Function Training Intervention for Healthy Aging in the Elderly Population
The study, entitled "PotenziaMente: Cognitive Training in Aging," is a clinical trial designed to evaluate the effectiveness of an individualized tablet-based cognitive training program targeting executive functions (e.g.…
- Trial name
- NCT07639203
- Testing
- Remote Cognitive Training, Supervised In-Person Cognitive Training
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Trento
Mild Intellectual Disability, Borderline Intellectual Functioning
Intervention Utilizing a Computerized Cognitive Rehabilitation Program (D-kit/EF1)
The goal of this exploratory clinical trial is to test the effects of the computerized cognitive rehabilitation program (D-kit/EF1) for children with borderline intellectual functioning or mild intellectual disability after its…
- Trial name
- NCT05933005
- Testing
- D-kit/EF1
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, San Francisco
Cognitive Impairment, Perceived Stress
Robot-Assisted Meditation for Older Adults With Cognitive Concerns
While traditional app-based mindfulness meditation programs relying solely on audio guidance have shown potential benefits for older adults, the programs often face challenges such as low engagement.
- Trial name
- NCT07435220
- Testing
- Robot-Guided Meditation, Audio-Only Robot
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Hearing Loss
Randomised Study of Web-Based Auditory Training With Varying Perceptual and Cognitive Demands on Training Gains and Generalised Speech, Cognitive, and Communication Outcomes
WP1: PLUS-Auditory Training The goal of this experimental study is to better understand how task difficulty affects on-task learning thresholds and generalised benefits in two PLUS auditory training tasks involving perceptual and…
- Trial name
- PLUS-Optimal (NCT07506408)
- Testing
- Practice Listening and Understand Speech (PLUS)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Vascular Stiffness, Cognitive Change
Blueberry Study Aimed at Improving Cognition and Peripheral Blood Flow
Blueberries are rich in the content of a variety of biologically active chemicals that contribute to their health properties. The consumption of blueberries has beneficial effects on vascular function and brain health and…
- Conditions
- Vascular Stiffness, Cognitive Change, Blood Pressure
- Trial name
- NCT04015258
- Testing
- Blueberries, Blueberry powder, Blueberry components capsules
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Sarcopenia, Cognitive Frailty
Effectiveness of a ReMIND Diet Intervention on Sarcopenia, Cognitive Frailty and Nutritional Status in Older Adults
This research is a single-blinded, 12-week, two-arm cluster randomized controlled trial to evaluate the effectiveness of a Malaysian-adapted MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet retort meal…
- Conditions
- Sarcopenia, Cognitive Frailty, Nutritional Interventions
- Trial name
- ReMIND (NCT07325760)
- Testing
- PPR Seri Alam Fasa 2 (Intervention Group)
- Where
- 2 sites in Malaysia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Depressive Symptoms
TreadWill, an Automated Intervention for Depressive Symptoms
TreadWill is a fully automated digital intervention that provides a multi-modal treatment for depressive symptoms. It includes: 1. Slides and interactive text-based conversations based on Cognitive Behavioral Therapy (CBT); 2.
- Trial name
- NCT04703491
- Testing
- Interactive and full-featured intervention, Feature-limited CCBT, Waitlist control
- Where
- India
- Volunteers
- 500 people
- Sponsor
- Indian Institute of Technology Kanpur
Mild Cognitive Impairment
Oral Health Intervention Pilot Study for Individuals With Memory Problems
The purpose of this study is to pilot test an intervention to improve oral health for individuals with memory problems. The results from this study will assist in developing prevention and intervention programs aimed at…
- Trial name
- NCT01808235
- Testing
- Oral Health Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Relatives, Health Care Providers
A Complex Intervention Study on a Palliative Rehabilitation Blended Learning Program to Support Relatives and Health Care Providers of People With ALS and Cognitive Impairments in Coping With Challenges
A complex intervention study on a palliative rehabilitation blended learning program to support relatives and health care providers of people with ALS and cognitive impairments in coping with challenges.
- Conditions
- Relatives, Health Care Providers, Cognitive Impairment, Rehabilitation
- Trial name
- NCT04638608
- Testing
- EMBRACE (relatives), EMBRACE (Health care providers)
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Danish Rehabilitation Centre for Neuromuscular Diseases
Autism Spectrum Disorder
OCCUPATIONAL THERAPY INTERVENTIONS ON COGNITIVE PERFORMANCE IN CHILDREN WITH AUTISM SPECTRUM DISORDER
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and interaction, as well as restricted and repetitive patterns of behavior.
- Trial name
- COGNITIVE PERF (NCT07818538)
- Testing
- Virtual Reality-Supported Cognitive-Focused Occupational Therapy, Structured Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Biruni University
Cognitive Impairment, Cognitive Decline
Digitally Supported Lifestyle Programme to Promote Brain Health Among Older Adults
Previous research has shown that a healthy lifestyle, including a balanced diet, physical and social activity, and management of vascular risk factors can support both cardiovascular and brain health.
- Conditions
- Cognitive Impairment, Cognitive Decline, Dementia
- Trial name
- LETHE (NCT05565170)
- Testing
- Structured ICT-assisted multimodal lifestyle intervention, Self-guided multimodal lifestyle intervention
- Where
- 4 sites in Austria, Finland and 2 more
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare