Clinical trials: Cognitive Investigation
Dementia, Mild Cognitive Impairment
A Digital Cognitive Behavioural Therapy for Insomnia Intervention in Mild Cognitive Impairment and Mild Dementia
The purpose of this study is to assess the feasibility of conducting a definitive randomised controlled trial that will determine the effectiveness of a digital cognitive behavioural therapy for insomnia intervention (Sleepio) in…
- Conditions
- Dementia, Mild Cognitive Impairment, Insomnia, Sleep
- Trial name
- REST (NCT07363928)
- Testing
- Digital cognitive behavioural therapy for insomnia
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University College Cork
Cognitive Impairment, Poor Nutrition
The PROtein Enriched MEDiterranean Diet and EXercise Trial for Older Adults At Risk of Undernutrition
PROMED-EX is a single-blind, parallel group randomised controlled trial to determine the effect of a PROtein enriched MEDiterranean diet (PROMED) in comparison to a PROtein enriched MEDiterranean diet and EXercise (PROMED-EX)…
- Conditions
- Cognitive Impairment, Poor Nutrition, Cognitive Decline
- Trial name
- PROMED-EX (NCT05166564)
- Testing
- A Protein Enriched Mediterranean Diet (PROMED) Intervention, A Protein Enriched Mediterranean Diet & Exercise (PROMED-EX) Intervention
- Where
- United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Regional Cerebral Blood Flow, Mild Cognitive Impairment
Effects of Photobiomodulation on Changes in Cognitive Function and rCBF in MCI
This pilot study has two goals. The first is to see if the cognitive improves when VA and CA are stimulated in MCI patients, and the second is to do an explanatory data analysis to see if that improves cognitive in relation to…
- Conditions
- Regional Cerebral Blood Flow, Mild Cognitive Impairment, Cognitive Function
- Trial name
- NCT04721093
- Testing
- Photobiomodulation device
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Pusan National University Yangsan Hospital
Disability, Intellectual
Importance of Multidimensional Assessments in Accompanying Schooling of Children With Mild to Moderate Intellectual Disability.
The EVAL'ID study aims to demonstrate the value of a multidimensional assessment in accompanying schooling of children with Intellectual Disability.
- Trial name
- EVAL'ID (NCT03088007)
- Testing
- Cognitive, adaptive, behavioral and academic assessment
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hospices Civils de Lyon
Hearing Loss, Age Related Hearing Loss
Task Training In Older Adults With Age-Related Hearing Loss
This study aimed to examine the effects of single and dual-task training on physical function, cognitive function, quality of life, balance, concerns about falling, and activities of daily living in the elderly with age-related…
- Conditions
- Hearing Loss, Age Related Hearing Loss, Physical Disability, Vestibular Disease
- Trial name
- NCT05190081
- Testing
- TASK TRAINING
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Pamukkale University
Mild Cognitive Impairment (MCI), Aging
Elderberry Functional Gum and Cognitive & Oral Health in Older Adults
Globally, the aging population is increasing rapidly, leading to a dramatic rise in the prevalence of Alzheimer's disease and other types of dementia.
- Conditions
- Mild Cognitive Impairment (MCI), Aging, Oral Microbiome
- Trial name
- NCT07054645
- Testing
- Elderberry Anthocyanin Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Fibromyalgia
Cognitive Dysfunction in Fibromyalgia Patients
Fibromyalgia is a common rheumatologic disorder. Many patients complain of cognitive dysfunction as part of their symptoms. The investigators aim to assess this cognitive dysfunction through extensive neuro-cognitive testing.
- Trial name
- NCT01655537
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Hadassah Medical Organization
Acquired Brain Injury
Cognitive Motion-Based Videogames Exploratory Study in Acquired Brain Injury
This study aims to assess the feasibility of Intendu Cognitive Motion-Based Videogames in Acquired Brain Injury (ABI) patients in inpatient treatment and in the community and to evaluate the effects of training on patients'…
- Trial name
- NCT02753244
- Testing
- Motion Based Cognitive Video Games Software, iPad Apps
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Intendu Ltd.
Breast Cancer, Chemo-brain
Assessment of Brain Cognitive Impairment in Breast Cancer
To explore the cognitive impairment caused by chemotherapy and endocrine therapy in premenopausal breast cancer patients and to find biomarkers with early predictive effect on this cognitive impairment by using multimodal…
- Conditions
- Breast Cancer, Chemo-brain, Endocrine Therapy
- Trial name
- NCT05305092
- Testing
- PET/MRI, psychobehavioral tests and questionnaires, serum biomarkers and stool sample
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Cognitive Impairment
The Effect of Exercise on Cognition in Older Adults At-risk for Diabetes: A Feasibility Pilot Study
Older adults with type 2 diabetes experience cognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (based on body mass, glucose levels) are at higher…
- Trial name
- NCT03254381
- Testing
- Resistance Training, Balance and Tone Training
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Western University, Canada
Medical Education
Basic Life Support (BLS) and Barriers to Cross-Cultural Education
This is a randomized, multi-center intervention trial comparing two educational programs on healthcare provider performance in the Botswana national hospital system.
- Trial name
- BLSinBotswana (NCT00715767)
- Testing
- Assessment
- Volunteers
- 215 people
- Sponsor
- Children's Hospital of Philadelphia
Mild Cognitive Impairment (MCI), Parkinson Disease (PD)
A Study of CST-2032 in Subjects With Cognitive Impairment
This study will evaluate the effects of CST-2032 when administered with pre-administered CST-107 on safety, tolerability, cognition, cerebral perfusion, and cerebral metabolism in patients with cognitive impairment.
- Trial name
- NCT05033912
- Sponsor
- CuraSen Therapeutics, Inc.
Parkinson's Disease (PD), Dual-task
The Effects of Dual Task Training With Different Task Priorities on Physical Performance and Cognitive Status in Patients With Parkinson's Disease
This study was planned to investigate and compare the effects of variable and fixed priority dual task training on balance, walking skills, mobility and cognition in patients with Parkinson's disease.
- Conditions
- Parkinson's Disease (PD), Dual-task, Balance, Walking
- Trial name
- NCT06794177
- Testing
- Variable priority dual task training, Fixed priority dual task training, Single task training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Visual Cognitive Deficits
Evaluation of the Efficacy of Optometric Rehabilitation on Visual Cognitive Deficits in Children
Visual cognitive deficits in children are frequent, with an impact on working and daily activities. Optometric therapy may improve those functions, however few studies have been performed.
- Trial name
- NCT02061501
- Testing
- Optometric therapy during 6 months, Optometric therapy during 12 months
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Strasbourg, France
Mild Cognitive Impairment (MCI), Mild Dementia
Study to Evaluate the Efficacy and Safety of KDS2010 in Patients With Alzheimer's Disease With Mild Cognitive Impairment and Mild Dementia Due to Alzheimer's Disease
A randomized, double-blind, placebo-controlled, dose-finding Phase 2a clinical trial will be conducted to evaluate the efficacy and safety of KDS2010 in patients with Mild Cognitive Impairment (MCI) due to Alzheimer's disease…
- Conditions
- Mild Cognitive Impairment (MCI), Mild Dementia, Alzheimer's Disease
- Trial name
- NCT07027072
- Testing
- KDS2010
- Where
- 8 sites in South Korea
- Volunteers
- 114 people
- Sponsor
- NeuroBiogen Co., Ltd
Cognitive Dysfunction
PREsurgical Cognitive Evaluation Via Digital clockfacEdrawing
This study leverages a modernized digital version of a well-known cognitive screening tool to examine pre and post operative cognitive function after surgery in adults age 65 years or more.
- Trial name
- PRECEDE (NCT03175302)
- Testing
- digital cognitive testing
- Where
- United States
- Volunteers
- 25,240 people
- Sponsor
- University of Florida
Alzheimer's Disease
Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18F-florbetapir (AV-45) PET Examination
Dementia is a common neurodegenerative syndrome in aged population. Alzheimer's disease (AD) is the most common disease. The main pathological findings in AD include senile plaques (SP) and neurofibrillary tangles (NFT).
- Trial name
- PMPBB3/AV45 (NCT04305210)
- Testing
- F-18 PMPBB3, 18F-florbetapir
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cognitive Function Assessment, Mild Cognitive Impairment
Prediction of Cognitive Test Performance Using AI-Based Analysis of Narrative Speech
This study aims to evaluate a new artificial intelligence (AI)-based method for measuring cognitive function using speech recordings.
- Conditions
- Cognitive Function Assessment, Mild Cognitive Impairment, Subjective Cognitive Decline
- Trial name
- NCT07511270
- Testing
- AI-Based Storytelling Speech Assessment
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Depressive Symptoms, Quality of Life
Evaluation of MBCT Implemented in Vietnamese Buddhist Pagoda
Background Depression presents a substantial public health burden around the world. Evidence-based psychotherapy treatments (psychotherapy EBT) for depression exist but access is often limited, particularly in low- and…
- Trial name
- MBCT-VN (NCT06598579)
- Testing
- Mindfulness-based Cognitive Therapy, Treatment-as-usual involving Buddhist meditation
- Where
- Vietnam
- Volunteers
- 160 people
- Sponsor
- Vanderbilt University
Addiction
Just-In-Time Adaptive Interventions for Addictive Behaviors
Background: Many smartphone apps intend to help people with addictions. But not enough is known about how they should work. Researchers want to study an app that gives people the advice they need, just when they need it.
- Trial name
- NCT03538652
- Testing
- Formative Interviews (not an intervention), Cognitive-behavioral therapy (CBT), Acceptance and commitment therapy (ACT)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
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