Clinical trials: Cognitive Investigation
Neurocognitive Disorders
Cognitive Functions on Coronary Surgery
The aim of this study is to examine the effects of different but safe levels of arterial oxygen levels used in cardiac surgeries on cerebral oxygenation during the operation.
- Trial name
- NCT04725708
- Testing
- procedure: cerebral oxygenation intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Multiple Sclerosis
Fatigability in Persons With Multiple Sclerosis: Inputs From Cognition, Walking and Coordination
Walking impairments occur in 93% of persons with MS (pwMS) within 10 years of diagnosis. Besides the impact of muscle weakness or hypertonia, one is increasingly aware about the symptom of fatigability.
- Trial name
- NCT05412043
- Testing
- Dance therapy, Psychometric properties (Validity, Reliability) of interlimb coordination- and cognitive-fatigability
- Where
- 2 sites in Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Huntington Disease
A Pilot Evaluation of Mindfulness-based Cognitive Therapy for People With Huntington's Disease
This is a pilot study to see whether mindfulness-based cognitive therapy, which is a type of psychological therapy, is able to improve the psychological wellbeing of people who have the gene for Huntington's disease.
- Trial name
- NCT02464293
- Testing
- Mindfulness-based cognitive therapy
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Lancaster University
Cardiac Disease, Depression and Quality of Life
Evaluation of a Remote Behavioural Stress Recovery Intervention for Myocardial Infarction Patients Younger Than Fifty-five (BRIM-55): A Feasibility Study
The goal of this feasibility study is to learn if the randomised controlled trial evaluating the Remote-delivery Balance in Everyday Life (rBEL) programme for adults younger than 55 years who have experienced a myocardial…
- Conditions
- Cardiac Disease, Depression and Quality of Life, Cardiac Distress, Myocardial Infarction
- Trial name
- BRIM-55 (NCT07706816)
- Testing
- Remote-delivery Balance in Everyday Life (rBEL) Program for Myocardial Infarction Patients Younger Than 55 Years With Cardiac Distress
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Critical Illness, Post Intensive Care Syndrome (PICS)
Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)
This two-arm, parallel-group randomized clinical trial investigates the effectiveness of an additional telerehabilitation program compared with standard care in patients with Post-Intensive Care Syndrome (PICS).
- Conditions
- Critical Illness, Post Intensive Care Syndrome (PICS), Cardiopathy
- Trial name
- CARDIO-PICS (NCT07599306)
- Testing
- Tele-rehabilitation, Standard of Care
- Where
- Italy
- Volunteers
- 326 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Substance Abuse
Evaluation of Web-Based Recovery Monitoring With Clinical Alerts
The specific aims of the project are to conduct a three-phase study to develop a data-driven Clinical Alert feature to the RecoveryTrack™ Concurrent Recovery Monitoring (CRM) system and test its efficacy, as follows: Phase I …
- Trial name
- NCT01465555
- Testing
- Cognitive Behavioral Intervention
- Where
- 4 sites in United States
- Volunteers
- 389 people
- Sponsor
- Treatment Research Institute
Dance, Older Adults
Dose-response Effect of Community Dance Programme
The goal of this interventional study is to examine the dose-response effect of Community Dance Programme (CDP) on the physical, cognitive and psychological health of pre-frail and mildly frail community-dwelling older adults.
- Conditions
- Dance, Older Adults, Frailty at Older Adults, Active Ageing
- Trial name
- NCT07081191
- Testing
- Dance, Active Control
- Where
- Singapore
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Multiple Sclerosis, Relapsing-Remitting
Multiparametric Assessment to Investigate Prognostic Factors for Disease Evolution a nd Evolutionary Patterns of Cognitive Status in RRMS
This prospective study combining non conventional MRI techniques, neuropsychological screening tools, and a neurophysiological work-up using a sensitive and validated battery, will evaluate the predictive value of these measures…
- Trial name
- COGNIT-MS (NCT05510817)
- Testing
- Multiparametric assessment
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital of Mont-Godinne
Postoperative Cognitive Dysfunction
Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical Prostatectomy
Evaluation of the effect of preoperative intravenous administration of amantadine sulfate on the prevention of the development of early cognitive dysfunction in elderly patients undergoing laparoscopic radical prostatectomy
- Trial name
- NCT03988010
- Testing
- Amantadine Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- TC Erciyes University
DUAL TASK, DEGLUTİTİON
Cognitive - Motor Dual Task and Swallowing
Swallow and dual-task are a current issue and there are few studies on this subject. These studies have shown that as a result of dual-task interaction, swallowing is affected by attention and cognitive capacity, and dual-task…
- Conditions
- DUAL TASK, DEGLUTİTİON, COGNİTİVE FUNCTİON, ACTİVİTİES OF DAİLY LİVİNG
- Trial name
- NCT05452135
- Testing
- Observation of visual, audotory and motor reaction time
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Atılım University
Dementia, Alzheimer Disease 1
Study of APH-1105 in Patients With Mild to Moderate Alzheimer's Disease
This is a Phase 2 study assessing the safety, tolerability and efficacy of intranasal delivery of APH-1105 for the treatment of mild to moderate Alzheimer's in adult.
- Conditions
- Dementia, Alzheimer Disease 1, Alzheimer Disease 2, Alzheimer Disease 3
- Trial name
- NCT03806478
- Testing
- APH-1105
- Volunteers
- 60 people
- Sponsor
- Aphios
Insomnia
Residual Effects of Zolpidem Tartrate Extended Release and Eszopiclone Vs Placebo
Investigation of Psychomotor and Cognitive Residual Effects of Single Oral Doses of Zolpidem Tartrate Extended Release 12.5 mg and Eszopiclone 3 mg Compared to Placebo in Healthy Young Volunteers, Using Flurazepam 30 mg as an…
- Trial name
- NCT00283790
- Testing
- zolpidem tartrate
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sanofi
Lewy Bodies Disease, Alzheimer Disease
Diagnostic Evaluation of Dementia with Lewy Bodies Using a Multimodal Approach
Dementia with Lewy body disease (DLB) is the second leading cause of degenerative cognitive disorder after Alzheimer's disease (AD). Its variable clinical expression makes diagnosis difficult.
- Conditions
- Lewy Bodies Disease, Alzheimer Disease, Cognitive Impairment
- Trial name
- EEG-EDELY (NCT06068361)
- Testing
- EEG
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Obstructive Pulmonary Disease
pCO2 Oscillations During Exercise: Relation to Cerebral Blood Flow and to Cognitive Dysfunction in COPD
Investigators wish to identify a relationship between substantial changes in carbon dioxide partial-pressure (pCO2), which frequently occur during the transitions from rest to exercise (ΔpCO2 >4 millimeters of mercury [mmHg] from…
- Trial name
- NCT02660437
- Testing
- Pulmonary Rehabilitation program
- Where
- Germany
- Volunteers
- 91 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Mild Cognitive Impairment
Application and Revision of Montreal Cognitive Assessment in Chinese Retirees
The study was designed to employ MOCA to screen mild cognitive impairment (MCI) in military retirees and to analyze the associated risk factors. As such, MOCA was revised to be validated for the Chinese context.
- Trial name
- ARMOCA (NCT02483754)
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Intellectual Developmental Disorder
Emotional Processes in Adults With Intellectual Developmental Disorder
Emotions play a crucial part in the quality of life, interpersonal relationships and mental health in general. In adults presenting with intellectual developmental disorder (IDD), emotional abilities may be hindered, thus leading…
- Trial name
- EmoTDI (NCT07303270)
- Testing
- ACQUISS protocol assessing emotional processing.
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Multiple Myeloma
Patient and Care Partner Experiences Living With Multiple Myeloma (PaCE-MM)
This research study is explore the impact over time of multiple myeloma and its associated treatments on the physical and cognitive function and quality of life of patients and their care partners and how these impacts affect the…
- Trial name
- PaCE-MM (NCT05276622)
- Testing
- Comprehensive Geriatric Assessment, Qualitative patient-care partner interviews, Surveys on well-being and function
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Recurrent Depressive Disorder
Study to Evaluate Cognitive Functioning in Remitted Depression During Treatment With Fluvoxamine
Open label, non-comparative, prospective study to evaluate cognitive functioning in remitted depression outpatients during long-term preventive treatment with Fluvoxamine (Fevarin®)
- Trial name
- NCT02016261
- Testing
- Fluvoxamine
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Moscow Research Institute of Psychiatry
Brain Tumor
Evaluation of Cognitive-Communication Deficits Following Treatment of Primary Brain Tumor Patients
This study is to evaluate which cognitive-linguistic symptoms are most commonly experienced following brain tumor treatment. Cognitive surveys will be administered after treatment of primary brain tumor cancer.
- Trial name
- NCT03090386
- Testing
- Cognitive Surveys
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Stroke, Post-Stroke Cognitive Impairment (PSCI)
Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment
This pilot study aims to evaluate the feasibility of implementing immersive virtual reality (VR) in cognitive rehabilitation for adults with post-stroke cognitive impairment receiving outpatient therapy.
- Conditions
- Stroke, Post-Stroke Cognitive Impairment (PSCI), Cognitive Dysfunction, Virtual Reality Therapy
- Trial name
- NCT07125170
- Testing
- Kinesix XR on Meta Quest 3
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
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