Clinical trials: Cognitive Investigation
Mild Cognitive Impairment, Early Alzheimer's Disease
Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease
The purpose of this study is to determine whether daily treatment with this new treatment approach, called COT would be effective in protecting the memory and brain regions of people who are already showing signs of memory loss.
- Conditions
- Mild Cognitive Impairment, Early Alzheimer's Disease, Memory Impairment
- Trial name
- NCT05122598
- Testing
- COT
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Evon Medics LLC
Attention Deficit Hyperactivity Disorder
Added Value of the Oculomotor and Cognitive Examination in the Management of Patients With ADHD
ADHD is a neurodevelopmental disorder characterized by symptoms of inattention and / or hyperactivity-impulsivity that affects nearly 6% of school-aged children and persists into adulthood.
- Trial name
- NCT03411434
- Testing
- Methylphenidate Oral Tablet
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Rouffach
Chronic Low Back Pain
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response
VETERANS ONLY. Chronic low back pain (cLBP) is common. Most Americans will have at least one episode of low back pain in their lifetimes.
- Trial name
- SCEPTER (NCT04142177)
- Testing
- Pain EASE, Tailored exercise, Continued Care and Active Monitoring
- Where
- 19 sites in United States
- Volunteers
- 2,529 people
- Sponsor
- VA Office of Research and Development
Cerebellar Ataxia
Dual Task Training for Cerebellar Ataxia
Combining cognitive training with physical training to improve balance is a new approach for reducing the risk of falls in patient populations who are at risk for falls.
- Trial name
- NCT04648501
- Testing
- Dual-task training
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Mild Cognitive Impairment
Protocol of Multi-domain Attention Training
This study sought to investigate the changes in attention in older adults with mild cognitive impairment after Multi-domain Attention Training .
- Trial name
- NCT03379519
- Testing
- Multi-domain Attention Training (MAT), Passive information activities (PIA)
- Volunteers
- 60 people
- Sponsor
- Ministry of Science and Technology, Taiwan
Diabetes Mellitus Type 1, Diabetes Mellitus Type 2
MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes
T2D and cognitive impairment are two of the most common chronic condition found in persons 60 years and older. Diabetes type 2 increases with age and studies suggest that the diabetes is one of the risk factor for cognitive…
- Conditions
- Diabetes Mellitus Type 1, Diabetes Mellitus Type 2, Mild Cognitive Impairment
- Trial name
- NCT02545062
- Testing
- MoCa test
- Where
- Israel
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Schizophrenia Cognition Autobiographical Memory Cognitive Remediation, SCHIZOPHRENIA 1 (Disorder)
Acceptability and Efficacy of Group Reminiscence Intervention in a Sample of Patients With Schizophrenia
The study aimed to test whether group reminiscence intervention for inpatients with schizophrenia is feasible, acceptable and preliminary effective.
- Conditions
- Schizophrenia Cognition Autobiographical Memory Cognitive Remediation, SCHIZOPHRENIA 1 (Disorder), Hospitalized Adult Patients
- Trial name
- NCT07512843
- Testing
- Group reminiscence therapy
- Where
- Jordan
- Volunteers
- 38 people
- Sponsor
- The Hashemite University
Mild Cognitive Impairment
Cognitive Intervention in Mild Cognitive Impairment With or Without White Matter Hyperintensities
This is a non-pharmacological study evaluating the differential effects of a computerized cognitive stimulation program according to the existence or not of white matter hyperintensities in elderly with mild cognitive impairment.
- Trial name
- NCT03195803
- Testing
- Computerized Cognitive Stimulation
- Volunteers
- 51 people
- Sponsor
- Leila DJABELKHIR
Cognitive Impairment Associated With Schizophrenia
Study to Evaluate the Safety and Efficacy of MEM 3454 as Adjunctive Treatment in Combination With a Preexisting Antipsychotic in Patients With Cognitive Impairment Associated With Schizophrenia
To establish the proof of concept that MEM 3454, used as add-on pharmacotherapy, is a safe and effective treatment in patients with cognitive impairment associated with schizophrenia (CIAS).
- Trial name
- NCT00604760
- Testing
- MEM 3454
- Where
- 44 sites in United States
- Volunteers
- 160 people
- Sponsor
- Memory Pharmaceuticals
Alzheimer Disease, Cognitive Change
Evaluation of the Contribution of Regular Cognitive Exercises to Treatment in Patients With Alzheimer's Disease
In this study, it is aimed to compare the effects of cognitive exercises applied on long-term internet environment to the cognitive level of patients who received donepezil, memantine or donepezil / memantin combination therapy.
- Trial name
- NCT03954613
- Testing
- Ebicomb
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people
- Sponsor
- Neutec Ar-Ge San ve Tic A.Ş
People With Subjective Cognitive Impairement (SCI)
Physical Activity Component of the Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER)
The Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER) is a six-month multimodal, multicenter study aimed at people with Subjective Cognitive Impairement (SCI).
- Trial name
- GINGER (NCT06528379)
- Testing
- Physical Activity
- Where
- 2 sites in Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Patras
Chronic Ankle Instability, Chronic Ankle Instability, CAI
The Effect of Cognitive Dual-Task on Athletic Performance Parameters in Volleyball Players With and Without Chronic Ankle Instability
The aim of this study is to investigate the effect of the cognitive dual-task on athletic performance parameters in volleyball players with and without chronic ankle instability.
- Conditions
- Chronic Ankle Instability, Chronic Ankle Instability, CAI, Volleyball, Volleyball Players
- Trial name
- NCT07439861
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pain, Postoperative, Analgesics, Opioid
Phase 1: Randomized Evaluation of a System to Deliver Mobile Cognitive Behavioral Therapy
The clinical study described in this Clinical Investigation Plan (CIP) will be completed in two stages, Phase I and Phase II. The results of Phase I will confirm patient use of InCaveo's EOA system with integrated mobile CBT but…
- Trial name
- P1RESPECT (NCT04836169)
- Testing
- InCaveo's EOA system with integrated mobile CBT
- Volunteers
- 30 people
- Sponsor
- InCaveo
Renal Insufficiency
Behaviour and Cognitive Evaluation for Dialysis Elderly Patients (BCDE)
The trial is a multicenter, prospective, randomized, open study. A total of 500 elderly patients aged over 75 years with renal insufficiency stage 5 will be included in the study after signed informed consent.
- Trial name
- BCDE (NCT00847275)
- Testing
- Exclusive nephrology follow-up, Geriatric follow-up
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Nantes University Hospital
Depression
A Computerized Depression Intervention in Veterans
Depressive symptoms are common among Veterans and associated with significant impairment. Timely intervention has the potential to improve mental health outcomes and restore functioning.
- Trial name
- Deprexis (NCT06217198)
- Testing
- Deprexis
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- VA Office of Research and Development
HIV-Dementia, HIV-Associated Cognitive Motor Complex
PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)
The purpose of this protocol is to measure a receptor in the brain using positron emission tomography (PET) that is involved in inflammation.
- Conditions
- HIV-Dementia, HIV-Associated Cognitive Motor Complex, AIDS Encephalopathy, AIDS Dementia Complex
- Trial name
- NCT00459693
- Testing
- [11C]PBR28
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Type 2 Diabetes Mellitus (T2DM), Cognitive Impairment
Exercise and PPARGC1A rs8192678 in Older Adults With Type 2 Diabetes and Cognitive Impairment
This completed single-arm interventional study evaluated changes in metabolic control, cognitive function, and health-related physical fitness following a 12-week combined aerobic and resistance exercise program in older adults…
- Trial name
- Association Be (NCT07711834)
- Testing
- Combined aerobic and resistance exercise
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Harbin Sport University
COVID 19, Oxydative Stress
Oxidative Stress and Cognitive Dysfunction After COVID-19
This observational cohort study will investigate the association between oxidative stress biomarkers and post-COVID-19 cognitive impairment.
- Conditions
- COVID 19, Oxydative Stress, Cognitive Impairments
- Trial name
- NCT07029048
- Testing
- Standard Post-COVID Rehabilitation Program
- Where
- Kazakhstan
- Volunteers
- 45 people
- Sponsor
- Karaganda Medical University
COVID-19
Investigation of the Effect on Cognitive Skills of COVID-19 Survivors
Investigation of the Effect Of Green Walking and Intelligence Games on the Cognitive Skills of Individuals Between the Ages of 50-70 Survived COVID-19 Disease The randomized controlled study to examine the effects of green…
- Trial name
- Cognitive (NCT05866263)
- Testing
- green walking and intelligence gam
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bayburt University
Lung Diseases, Interstitial
Assessment of Neuropsychiatric Function in Patients With Interstitial Lung Disease
Research on the impact of lung diseases on neuropsychological functioning has revealed impaired cognitive processing in patients with a variety of pulmonary disorders.
- Trial name
- NCT05719233
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
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