Clinical trials: Cognitive Performance in Healthy Adults
Stroke, Healthy Older Adults
Comparative Efficacy of Two Different Dual-task Balance Interventions
The objective of this study is to investigate the effects of two different dual-task balance interventions for stroke patients and older adults.
- Trial name
- NCT03234998
- Testing
- motor-cognitive dual-task training, cognitive dual-task training
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Cognitive Change, Stress
Acute Effects of Mango Leaf Extract (Zynamite®) on Cognitive Function, Mood and Stress
This study aims to assess the effects of a single dose of Zynamite® on performance across a number of cognitive domains (attention, working memory, episodic memory, executive function), as well as during a period of cognitively…
- Trial name
- MLE-ZYN (NCT04299217)
- Testing
- Zynamite®
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy Aging, Frailty
Characterisation of Functional and Cognitive Responses Following Olfactory Stimulation and/or Functional Training in Older Adults.
This randomized controlled trial will evaluate the effects of olfactory stimulation and/or multicomponent physical training in adults aged 60 years and older.
- Conditions
- Healthy Aging, Frailty, Cognitive Decline, Olfactory Dysfunction
- Trial name
- INNOLFACT 2 (NCT07623122)
- Testing
- Olfactory stimulation, Multicomponent physical training, Combined olfactory stimulation and multicomponent physical training
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Executive Dysfunction, Mild Cognitive Impairment (MCI)
Feasibility Study of Mixed Reality Exergame on Performance and Cortical Outcomes
The executive dysfunctions are a problem in individuals with MCI which predict conversion to dementia and is positively related to physical activity level.
- Trial name
- NCT06843733
- Testing
- Mixed reality exergame, Education
- Where
- Thailand
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy, Mild Cognitive Impairment
Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance?
With aging the amount of slow wave sleep decreases drastically and this disruption is markedly exaggerated in older adults suffering from mild cognitive impairment and Alzheimer's disease.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT04277104
- Testing
- Closed loop acoustic stimulation
- Where
- Switzerland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy, Cognitive Performance
Evaluate the Effects of Citicoline on Cognitive Performance in Healthy Adults
Cognizin is a patented form of citicoline, a natural compound of the brain tissue. It is believed that Cognizin can support brain function by boosting brain energy and protecting brain cells.
- Trial name
- NCT06906848
- Testing
- Cognizin®
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kirin Holdings Company, Limited
Acute Lymphoblastic Leukemia
Postural Control Under Different Cognitive Loads in Adult Survivors of Acute Lymphoblastic Leukemia and Age-Matched Healthy Individuals
The purpose of this study is to determine if adult survivors of childhood Acute Lymphoblastic Leukemia (ALL) enrolled on the SJLife (St.
- Trial name
- NCT03581045
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Mood and Cognitive Performance
The Effect of Date Fruit on Mood and Cognition in Healthy Adults
A number of studies have considered the neuroprotective effects of date fruit on neurodegenerative diseases in animals. However, so far no study has addressed the acute effects of date fruit on mood and cognitive performance in…
- Trial name
- NCT03350100
- Testing
- Acute effect of two Saudi cultivars of date fruit on mood and cognitive performance
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Athletic Performance, Cognitive Performance
Effects of Different Doses of Caffeine on Physical and Cognitive Performance in Female Handball Players
This study investigates how different doses of caffeine affect physical and cognitive performance in female handball players. Caffeine is widely used as a performance-enhancing substance, but its effects may vary depending on the…
- Conditions
- Athletic Performance, Cognitive Performance, Healthy Adult Females
- Trial name
- NCT07562256
- Testing
- Caffeine 3 mg/kg, Caffeine 6 mg/kg
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sinop University
Healthy, Healthy Adult Male
AI-Based Hamstring Injury Risk Analysis and Effects of the FUNBALL Program
This study investigates hamstring injury risk in football players using artificial intelligence-based motion analysis (OpenPose) and evaluates the effects of a targeted exercise intervention (FUNBALL).
- Trial name
- NCT07650006
- Testing
- FUNBALL Prevention Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Cognitive Performance, Age-Related Macular Degeneration
Lutein, Zeaxathin, and Fish Oil Supplementation
The goal of this clinical trial is to learn the impact of lutein, zeaxanthin, and fish oil (LZF) supplementation in healthy adults.
- Conditions
- Cognitive Performance, Age-Related Macular Degeneration, Bone Loss
- Trial name
- NCT06489873
- Testing
- Active Comparator (Lutein, zeaxanthin, and fish oil supplement (LZF)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Healthy Adult Females, Healthy Adult Male
Effects of Two Different Lion's Mane Extracts (Lions Mane Fruiting Body & Lions Mane Fruiting Body With Mycellium) on Cognitive Performance, Subjective Affect, Serum Biomarkers, and Gut Microbiota in Healthy Adults
A randomized, double-blind, placebo-controlled, parallel-arm study design, of healthy men and women assigned to one of three groups: 1 gram/day of MycothriveTM Nordic origin fruiting body lion's mane (M-LM), 1 gram/day of a…
- Trial name
- NCT07405957
- Testing
- Lion Mane (Hericium erinaceus) fruiting body extract - Nordic Origin, Lions Mane (Hericium erinaceus) Fruiting body and mycelium
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Applied Food Sciences Inc.
Healthy Aging, Mobility Limitation
Power Centering for Seniors
Walking difficulties, mobility decline and falls are prevalent among older adults. The incidence of each of these increases with age and the presence of each can negatively affect the quality of life in older adults.
- Conditions
- Healthy Aging, Mobility Limitation, Walking, Difficulty
- Trial name
- PCS (NCT04861831)
- Testing
- Power Centering for Seniors intervention
- Where
- Switzerland
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Department of Geriatric Medicine FELIX PLATTER
Cognitive Change
Acute Dose-ranging Effects of Mango Leaf Extract (Zynamite® 15%) on Cognitive Function and Cerebral Blood Flow
Zynamite® is a novel mango (Mangifera indica) leaf extract standardized to contain polyphenol mangiferin.It has previously been shown to enhance brain oxygenation, physical performance and ergogenic parameters following…
- Trial name
- NCT05580146
- Testing
- Zynamite® 15% 150mg, Zynamite® 15% 300mg, Zynamite® 15% 600mg
- Where
- United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy
Evaluate the Effects of Citicoline on Mood in Healthy Adults
The objective of this trial is to determine the effects of citicoline on mood in healthy Men and Women compared to a placebo.
- Trial name
- NCT07089238
- Testing
- Citicoline
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kirin Holdings Company, Limited
Cognitive Performance
Evaluation of the Effects of Berry Leaf Extract on Cognitive Processing in Healthy Elderly Adults
This study aims to explore the positive effect of a dietary supplement composed of berry leaf extract on the cognitive performance and regulation of stress, mood, sleep and fatigue in healthy elderly adults with self-reported…
- Trial name
- SLE (NCT06819163)
- Testing
- Berry leaf extract
- Where
- Belgium
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Seppic
Healthy People Programs
Boxing Training, Physical-functional Fitness and Cognitive Performance in Older Adults
The aim of the study is to evaluate and to compare the effects of two exercise regimes (Boxing Training -BT and Multicomponent Training -MT) and 12 weeks of follow-up on cognitive health status, physical-functional fitness, and…
- Trial name
- Boxe4Ageing (NCT05826314)
- Testing
- Boxing training, Exercise
- Where
- Portugal
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Mental Acuity
The Effect of Water Temperature on Heart Rate Variability and Cognition
Heart rate variability (HRV) is a key indicator of fitness, and stress resilience. Previous research has shown that HRV decreases under mental workload, including during tasks that require strict attention.
- Trial name
- NCT07654270
- Testing
- water
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arizona State University