Clinical trials: Cognitive Processing Speed
Impaired Processing Speed, Cognitive Impairment
Adderall XR and Processing Speed in Multiple Sclerosis (MS)
Cognitive impairment, or problems with thinking and memory, is common in multiple sclerosis (MS) and can occur independently of physical disability.
- Conditions
- Impaired Processing Speed, Cognitive Impairment, Multiple Sclerosis
- Trial name
- NCT01667484
- Testing
- Adderall XR 5mg, Adderall XR 10 mg
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre
Schizophrenia, Schizoaffective Disorder
Efficacy Study of Galantamine for Cognitive Impairments in Schizophrenia
The purpose of this study is to examine whether adjunctive galantamine is effective in the treatment of cognitive impairments in patients with schizophrenia.
- Trial name
- NCT00176423
- Testing
- galantamine
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Maryland, Baltimore
Multiple Sclerosis
Remote Exercise Effects on Cognitive Processing Speed in Multiple Sclerosis: A Pilot Trial
Cognitive processing speed (CPS) impairment is prevalent, impactful, and poorly-managed in multiple sclerosis (MS). Upwards of 67% of patients present with MS-related CPS impairment, which is associated with poor everyday life…
- Trial name
- REACT-MS (NCT05344040)
- Testing
- Remotely Delivered and Supported Aerobic Walking Exercise Training, Remotely Delivered and Supported Stretching and Toning Exercise Training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Kessler Foundation
HIV, Aging
A Novel Neurorehabilitation Approach for Cognitive Aging With HIV
The goal of this study is to conduct a small, self-contained project to test the hypothesis that tDCS will augment SOP cognitive remediation therapy (CRT) in older HIV+ adults.
- Trial name
- HtDCS (NCT02391311)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Alabama at Birmingham
Hyperbaric Oxygen Therapy
Measuring Cognitive Enhancement During Hyperbaric Oxygen Treatments
The aim of the current study was to examine the effect of short-term HBOT (hyperbaric oxygen treatments) on a range of cognitive abilities.
- Trial name
- NCT04358796
- Testing
- Hyperbaric oxygent treatment, Control hyperbaric oxygen treatment
- Where
- Israel
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Delirium, Dementia
Speed of Processing Training for Cognitive Deficits After Delirium in Older Adults
In this proposal, we will examine processing speed training (PST) as a potential intervention to reduce the risk of developing long-term cognitive impairment after a delirium episode.
- Trial name
- NCT03342989
- Testing
- Speed of Processing Training, Internet-Based Contact Control
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Alabama at Birmingham
Cognitive Function Abnormal, Atrial Fibrillation (AF)
Low-frequency Electrical Stimulation for Cognitive Enhancement in Atrial Fibrillation
Cognitive function in patients with atrial fibrillation (AF) is often impaired due to the complex influence of various factors (cerebral hypoperfusion, neurodegeneration, microemboli, hypertension, chronic inflammation).
- Trial name
- LESCAF (NCT07063381)
- Testing
- tVNS
- Where
- 2 sites in Russia
- Volunteers
- 60 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Cognitive Change, Processing, Visual Spatial
Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Processing.
The investigators' study is designed to test whether prolonged exposure to a martial arts-based intervention (three complex, partner exercises based on Filipino, Chinese and Thai martial arts practices), can improve cognitive…
- Trial name
- MATRICES (NCT05530148)
- Testing
- Martial Arts Training Group, Flexing, Toning and Balance
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Traumatic Brain Injury, Mild Traumatic Brain Injury
Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans
Older veterans with a history of mild brain trauma exhibit early cognitive challenges, especially in driving-related tasks. This is attributed to alterations in the brain's excitatory/inhibitory (E/I) balance.
- Conditions
- Traumatic Brain Injury, Mild Traumatic Brain Injury, Aging, Cognitive Decline
- Trial name
- BRAIN-SPEED (NCT06217575)
- Testing
- Alpha neurofeedback training, Visual Attention Training
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Mild Cognitive Impairment
Vision-based Speed of Processing Cognitive Training and Mild Cognitive Impairment
This project seeks to identify neural changes that occur in adults with mild cognitive impairment (MCI) after engagement in computerized cognitive training.
- Trial name
- NCT02559063
- Testing
- Vision-based speed of processing training, Mental leisure activities
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Breast Cancer Treatment, Cognitive Deficits
Treating Verbal Memory Deficits Following Chemotherapy for Breast Cancer
The primary purpose of this study is to test the effects of a targeted, computerized cognitive training program on verbal memory in older women who have undergone chemotherapy treatment for early-stage breast cancer.
- Trial name
- NCT03017560
- Testing
- Computerized cognitive treatment
- Volunteers
- 45 people
- Sponsor
- Northwestern University
Multiple Sclerosis
Internet-Delivered Lifestyle Physical Activity Intervention for Cognitive Processing Speed in Multiple Sclerosis
We propose a highly-informed, well-designed randomized controlled trial (RCT) that is critical for providing Class I evidence regarding an Internet-delivered physical activity (PA) intervention as a behavioral approach for…
- Trial name
- BIPAMS-Cog (NCT04518657)
- Testing
- Behavioral Intervention for Physical Activity in MS (BIPAMS), Wellness for MS (WellMS)
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- University of Illinois at Chicago
Cognition, Mood
Genistein, Equol, Cognitive Function and Mood: Acute. (GECFAMa)
Isoflavones (ISF) are naturally occurring compounds that can provide protective benefits for certain domains of cognitive function.
- Trial name
- GECFAMa (NCT07742514)
- Testing
- Genistein, Equol
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Reading
Executive Functions
Executive Functions Rehabilitation in Premature Children
in more than 60% of premature children processing speed and academic failures are observed, even in children with a normal cognitive level.
- Trial name
- NCT03639298
- Testing
- Intendu
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Vittore Buzzi Children's Hospital
Parkinson's Disease
Brain Fitness in Parkinson's Disease
The purpose of this study is to examine the feasibility and potential effectiveness of a cognitive training program among persons with Parkinson's disease.
- Trial name
- NCT01155349
- Testing
- InSight, No contact-control group
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of South Florida
Cognitive Decline, Aging
Multiple Joint, Structural Barbell Resistance Exercise Improves Information Processing Speed
This study investigated the effect of acute multiple joint, structural barbell resistance exercise on information processing speed and conflict-related neural activity in older adults via a crossover, sham control, randomized…
- Trial name
- NCT04534374
- Testing
- Resistance exercise
- Where
- Taiwan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Cognition, Mood
Genistein, Equol, Cognitive Function and Mood: Twelve-week. (GECFAMc)
Isoflavones (ISF) are naturally occurring compounds that can provide protective benefits for certain domains of cognitive function.
- Trial name
- GECFAMc (NCT07742501)
- Testing
- Equol, Genistein, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Reading
Traumatic Brain Injury, Stroke
VIrtual Reality in Cognitive Rehabilitation of Processing Speed for Persons With ABI
One hundred participants with acquired brain injury (ABI) will be included in a randomized controlled trial, with one group playing a commercially available VR game and the control group doing activities in their everyday as…
- Conditions
- Traumatic Brain Injury, Stroke, Acquired Brain Injury, Brain Injuries
- Trial name
- NCT05443542
- Testing
- Virtual Reality, Control intervention
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Multiple Sclerosis
Study of Exercise on Impact of Cognitive Functioning in Multiple Sclerosis Patients
Cognitive impairment affects roughly 50% of people with multiple sclerosis (MS). There are currently no satisfactory medical treatments for cognitive impairments related to MS and alternative forms of treatment are needed.
- Trial name
- NCT02106052
- Testing
- Aerobic exercise, Stretching and toning exercise
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Washington
Multiple Sclerosis
Study Describing Cognitive Processing Speed Changes in Relapsing Multiple Sclerosis Subjects Treated With Ozanimod (RPC-1063)
This is a multicenter, longitudinal, single-arm, open-label study to describe the change from baseline in cognitive processing speed, measured by the SDMT, in subjects with RMS treated with ozanimod HCl 1 mg at 3 years.
- Trial name
- ENLIGHTEN (NCT04140305)
- Testing
- RPC-1063
- Where
- 61 sites in United States, Canada and 1 more
- Volunteers
- 188 people
- Sponsor
- Celgene