Clinical trials: Cognitive Remediation Therapy
Schizophrenia, Schizoaffective Disorder
Adapted Cognitive/Affective Remediation for Cannabis Misuse in Schizophrenia
This study will integrate and adapt a cognitive remediation (Cognitive Enhancement Therapy [CET]) and an affect regulation (Personal Therapy [PT]) intervention for 50 individuals with schizophrenia that misuse cannabis.
- Trial name
- NCT01292577
- Testing
- CET/PT, Treatment as Usual
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pittsburgh
Psychotic Disorders
Hormonal and Inflammatory Biomarkers and Response to Cognitive Remediation in Recent-onset Psychosis
This study aims to explore whether hormones or inflammatory markers are associated with cognitive changes following cognitive remediation therapy (CRT) in people with a recent-onset psychotic disorder.
- Trial name
- NCT04418570
- Testing
- cognitive remediation, attendance to an Early Intervention Service for Psychosis
- Volunteers
- 28 people
- Sponsor
- Corporacion Parc Tauli
Early Psychosis
PSYCHE Cognitive Remediation & Social Recovery Study
This study is a pilot feasibility study embedded in the Early Intervention in Psychosis (EIP) services in Ireland. It explores the feasibility and acceptability of a combined cognitive remediation training and social recovery…
- Trial name
- NCT06032182
- Testing
- CRESTR Intervention, CRESTR Control
- Where
- 5 sites in Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Anorexia Nervosa
Efficacity of Cognitive Remediation Treatment Compared to a Controlled Group in Young Patient With Anorexia Nervosa
The aim of research is to test in a randomized clinical trial with active sessions, the efficacy of cognitive remediation therapy in children anorexia nervosa compared to a controlled group.
- Trial name
- RECOGAMEA (NCT02400541)
- Testing
- Cognitive remediation therapy, relaxation therapy
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Psychosis, Alcohol Use Disorder
Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis
Psychotic disorders impact 4.6 people per 1000 globally, with approximately 1.5 million Canadians affected. The age of onset for psychotic disorders often begin during the critical years of youth and early adulthood, resulting in…
- Conditions
- Psychosis, Alcohol Use Disorder, Cannabis Use Disorder
- Trial name
- NCT07056894
- Testing
- Action-Based Cognitive Remediation
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Schizophrenia
Cognitive Remediation Plus Aerobic Exercise in Schizophrenia Treatment
Cognitive remediation (CR) and aerobic exercise have separately shown promising results in schizophrenia cognitive improvement, despite this, the impact in improving functionality is still limited.
- Trial name
- NCT02864576
- Testing
- Cognitive Remediation_Aerobic Exercise, Cognitive Remediation_Health Promotion
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Parc de Salut Mar
Patients at Ultra-high Risk of Psychosis
Effects of Neurocognitive and Social Cognitive Remediation in Patients at Ultra-High Risk of Psychosis
Cognitive deficits are known to be a core feature of schizophrenia and seem to become manifest in the prodromal or Ultra-High Risk (UHR) state of psychosis.
- Trial name
- FOCUS (NCT02098408)
- Testing
- Cognitive remediation, Standard treatment
- Where
- Denmark
- Volunteers
- 146 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Substance-Related Disorders
Cognitive Remediation in Early Substance Abuse Treatment
This study is for the purpose of determining whether cognitive remediation may improve cognition and treatment response in patients entering substance abuse day treatment
- Trial name
- NCT00334217
- Testing
- Cognitive Remediation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- US Department of Veterans Affairs
Glioma, Brain Tumor, Primary
Cognitive Remediation Therapy for Brain Tumor Patients: Improving Working Memory
To investigate a computer-based Cognitive Remediation Therapy (CRT) for brain tumor patients at the Massey Cancer Center on measures of cognitive functioning (e.g., working memory, attention, processing speed, language…
- Trial name
- NCT03323450
- Testing
- CogMed®
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Early-onset Schizophrenia, Psychotic Disorders
Computerized Cognitive Remediation Therapy in Adolescents With a First Psychotic Episode
Cognitive deficits (CD) are considered one of the essential characteristics in psychotic disorders and occur throughout the course of the disease, being a key characteristic in the evolution of the disease and in the…
- Conditions
- Early-onset Schizophrenia, Psychotic Disorders, Cognitive Remediation Therapy, Cognition
- Trial name
- CCRT2019 (NCT05405946)
- Testing
- Computerized Cognitive Remediation Therapy, Treatment as Usual
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundació Sant Joan de Déu
Schizophrenia
Cognitive Remediation Method by Rhythmic, Vocal and Embodied Musical Learning for Stabilized Schizophrenic Patients
ARCoS is a pilot study evaluating the feasibility and preliminary effects of a method of cognitive remediation by a Rhythmic, Vocal and Embodied Musical Learning for a population of stabilized schizophrenic patients.
- Trial name
- ARCoS (NCT05124470)
- Testing
- cognitive remediation by musical training sessions
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Schizophrenia, Schizophreniform Disorder
Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode
The participants in the study will receive psychiatric treatment at the UCLA Aftercare Research Program. All participants in this 12-month RCT will receive cognitive training.
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
- Trial name
- NCT05890183
- Testing
- Cognitive training, Aerobic Exercise Program, Moderated Online Social Therapy (MOST)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Anorexia Nervosa
Inpatient Exposure Therapy and Response Prevention & Cognitive Remediation Therapy for Anorexia Nervosa
Exposure and response prevention (AN-EXRP) will help individuals with anorexia nervosa improve their eating behavior.
- Trial name
- NCT01174602
- Testing
- Exposure Therapy for AN (AN-EX/RP), Cognitive Remediation Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- New York State Psychiatric Institute
ADHD-add
MEthylphenidate in ADHD - Addiction(s) Comorbidity: Value of Adding a Cognitive Remediation Program to Improve Short- and Medium-term Therapeutic Response
MEthylphenidate in ADHD - Addiction(s) comorbidity: benefit of adding a cognitive remediation program to improve short- and medium-term therapeutic response
- Trial name
- META (NCT06906328)
- Testing
- Cognitive remediation program, with the PRESCO® software, Control program, with the AUDITICO® software
- Where
- 6 sites in France
- Volunteers
- 248 people
- Sponsor
- Nantes University Hospital
Alcohol Use Disorder
Cognitive and Metacognitive Remediation in Addiction Treatment.
Cognitive and metacognitive remediation in addiction treatment: Value of Adding a cognitive remediation program to improve overall self-efficacy in patients with alcohol use disorder.
- Trial name
- R'COMET (NCT07390877)
- Testing
- cognitive remediation group, Relaxation control program
- Where
- 6 sites in France
- Volunteers
- 130 people
- Sponsor
- Nantes University Hospital
Schizophrenia
Evaluation of a Cognitive Adaptive E-treatment in Schizophrenia-diagnosed Adults
This study is a multi-site, double-blind, randomized, controlled clinical trial to assess the safety and effectiveness of plasticity-based, adaptive, computerized-based cognitive remediation treatment versus a computer-based…
- Trial name
- e-CAeSAR (NCT01422902)
- Testing
- Plasticity-based Cognitive Training, Non-plasticity-based Training
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Posit Science Corporation
Anorexia Nervosa
Effectiveness of Cognitive Remediation Therapy in Improving Treatment Retention in People With Anorexia Nervosa
This study will evaluate the effectiveness of adding cognitive remediation therapy to cognitive behavioral therapy for treating people with anorexia nervosa.
- Trial name
- NCT00601822
- Testing
- Cognitive remediation therapy (CRT), Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Stanford University
Feeding and Eating Disorders, Anorexia Nervosa
Cognitive Training for Patients With Eating Disorders
Eating disorders are severe mental illnesses, mainly affecting adolescent- and young adult women. The prognoses for eating disorders are relatively poor, and a large part of patients with these illnesses do not benefit from…
- Conditions
- Feeding and Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- TCRTRCT (NCT03808467)
- Testing
- Cognitive Remediation Therapy, Treatment as usual
- Where
- 3 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Mild Cognitive Impairment
Computerized Memory Enhancing Treatment in MCI
The investigators propose to apply neuroplasticity-based computerized cognitive remediation (nCCR) to improve memory function in patients with Mild Cognitive Impairment (MCI).
- Trial name
- COMET (NCT05332522)
- Testing
- Neuroplasticity-based Computerized Cognitive Remediation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Vanderbilt University Medical Center
Multiple Sclerosis
Improving Cognitive Recovery in Multiple Sclerosis
This study aims to find out whether an adapted version of an existing cognitive rehabilitation program, CIRCuiTS (https://www.circuitstherapyinfo.com), can be used to improve everyday thinking skills for people with Multiple…
- Trial name
- CIRCuiTS-MS (NCT06877273)
- Testing
- CIRCuiTS-MS
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- King's College London