Clinical trials: Cognitive Risk Assessment
Alzheimer's Disease
Risk Evaluation and Education for Alzheimer's Disease
The purpose of this study is to determine the characteristics of those who obtain genetic susceptibility testing for Alzheimer's disease with APOE disclosure and to study the psychological and behavioral consequences of providing…
- Trial name
- REVEAL I (NCT00571025)
- Testing
- APOE Disclosure
- Where
- 3 sites in United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Chronic Stroke, Healthy Aging
Alternative Therapies for Improving Motor Impairment, Fall-risk and Overall Physical Function
Neurological impairment such as stroke and aging is a leading cause of adult disability. Traditional rehabilitative therapies can help regain motor function and ameliorate disability.
- Trial name
- NCT03758846
- Testing
- Cognitive-motor exergaming, Conventional balance Training, Dance Therapy for Stroke
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cognitive Changes Due to Organic Disorder (Finding), Dementia
Gerontology Research Programme: The Singapore Longitudinal Ageing Studies (SLAS I & II)
The Gerontology Research Programme (GRP) in the National University Singapore's Department of Psychological Medicine, was formed to coordinate and facilitate the conduct of multi-disciplinary research on in a wide range of…
- Conditions
- Cognitive Changes Due to Organic Disorder (Finding), Dementia, Mild Cognitive Impairment, Frailty
- Trial name
- SLAS (NCT03405675)
- Testing
- SLAS 1, SLAS 2
- Where
- Singapore
- Volunteers
- 6,183 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Mild Cognitive Impairment, Healthy
The Aerobic & Cognitive Exercise Study
The purpose of this study is to clarify the benefits to brain health and thinking processes that result from different forms of exercise.
- Trial name
- ACES (NCT02237560)
- Testing
- Cybercycle-Game, Cybercyle-Tour, Game Only
- Where
- 12 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Union College, New York
Subjective Cognitive Concerns (SCC)
Nonrandomized Evaluation of a Multidimensional Behavioral Intervention
This intervention is designed to promote enhanced use of compensation strategies including calendar and task list use, and organization systems, as well as increased engagement with brain health activities including physical…
- Trial name
- BBLite (NCT03717597)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Mild Cognitive Impairment (MCI)
A Prospective Cohort Study of Multimodal Biomarkers and Progression From Mild Cognitive Impairment to Dementia
This prospective, longitudinal observational cohort study will examine clinical, cognitive, blood-based, and neuroimaging features across the cognitive continuum.
- Trial name
- NCT07876570
- Testing
- Observational Multimodal Assessment
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Insomnia, Physical Health Functioning
Efficacy of a Computerized Cognitive Behavioral Treatment for Insomnia: Increasing Access to Insomnia Treatment to Decrease Suicide Risk
Insomnia is major problem among Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), and Operation New Dawn (OND) Veterans.
- Conditions
- Insomnia, Physical Health Functioning, Mental Health Functioning
- Trial name
- Vets Sleep (NCT03366870)
- Testing
- Computerized Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Depressive Symptom, Cognitive Functions
Cognicise Training for Seniors for Healthy Aging
The goal of this clinical trial is to assess the impact of two 8-week motor-cognitive exercise programs - Cognicise and yoga - on psychological, respiratory, cardiovascular, postural, and biochemical health in elderly women.
- Conditions
- Depressive Symptom, Cognitive Functions, Quality of Life, Physical Fitness
- Trial name
- NCT07098533
- Testing
- Cognicise Training, Yoga Training
- Where
- Poland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Physical Activity
Investigations of the Effects and Associated Neural Mechanisms of Different Exercise in People With Metabolic Syndrome
Metabolic syndrome (MetS) is a risk for many chronic diseases of middle-aged and older adults. Hence, prevention and treatment of MetS is a crucial global health issue.
- Trial name
- NCT05672940
- Testing
- Aerobic plus resistance training, Stretching plus breathing training
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy People Programs
Boxing Training, Physical-functional Fitness and Cognitive Performance in Older Adults
The aim of the study is to evaluate and to compare the effects of two exercise regimes (Boxing Training -BT and Multicomponent Training -MT) and 12 weeks of follow-up on cognitive health status, physical-functional fitness, and…
- Trial name
- Boxe4Ageing (NCT05826314)
- Testing
- Boxing training, Exercise
- Where
- Portugal
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Physical Inactivity
Cognitive Control to Boost Physical Activity Adherence
This trial is designed to develop and test the efficacy of cognitive training strategies to improve self-regulatory capacities for middle-aged adults to adopt and sustain a physically active lifestyle.
- Trial name
- BOOST (NCT06338774)
- Testing
- Cognitive training, Exercise
- Where
- 2 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Alzheimer's Disease, Aging
aeRobic Exercise and Cognitive Health
The purpose of the aeRobic Exercise and Cognitive Health (REACH) study is to understand how an aerobic exercise intervention might help promote brain health and cognition, thereby delaying the onset of clinical symptoms of…
- Trial name
- REACH (NCT02384993)
- Testing
- Enhanced Physical Activity
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Elderly, Exercise
Exergaming for Community-Dwelling Older Adults
This study aimed to utilize an interactive exergame mat system to develop a novel cognitive-physical training program and explore the training effects on physical performance, cognitive function, dual-task walking (DTW), and fall…
- Trial name
- NCT04284709
- Testing
- cognitive-physical training
- Where
- Taiwan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Accidental Falls, Aging
Evaluation of the Effects of a Cognitive-Motor Fall Prevention Program on Fall Risk Factors
The goal of this interventional study is to compare in community dwelling elderly people the effects of two physical activity programs to prevent accident falls : "SILVER XIII EQUILIBRE" program and "VIVIFRAIL" program, on…
- Conditions
- Accidental Falls, Aging, Mild Cognitive Impairment
- Trial name
- 13EVAL (NCT05625828)
- Testing
- Cognitive-motor Physical Activity, Multifactorial Physical Activity
- Where
- France
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- EZUS-LYON 1
Aging
Pomegranate Extract and Inflammageing
The growing ageing population has resulted in an increase in the prevalence of frailty, cognitive disorders and cardiovascular diseases, representing a major cause of disability in older adults.
- Trial name
- NCT05588479
- Testing
- Pomegranate extract, Control
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Systemic Sclerosis, Systemic Lupus Erythematosus
Clinical Risk Assessment of Cognitive Function in Systemic Autoimmune Diseases
Objectives: Systemic autoimmune diseases are chronic diseases characterized by chronic inflammation, vasculopathy, and autoimmune phenomena. Several organ involvements are typical, including the central nervous system.
- Conditions
- Systemic Sclerosis, Systemic Lupus Erythematosus, Myopathies, Inflammatory, Rheumatoid Arthritis
- Trial name
- NCT06029335
- Where
- Hungary
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Rheumatoid Arthritis, Cardiovascular Diseases
Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis:
One of the greatest success stories in rheumatology - the achievement of rheumatoid arthritis (RA) remission - is tempered by the fact that individuals with RA are dramatically under evaluated and under treated to reduce the risk…
- Conditions
- Rheumatoid Arthritis, Cardiovascular Diseases, Hyperlipidemias
- Trial name
- CARE RA (NCT04488497)
- Testing
- Cardiovascular Risk Assessment for Patients with Rheumatoid Arthritis, Standard of care
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Circadian Dysregulation
Maintaining Behavior Change: A 6-year Follow-up of Adolescent 'Night-owls'
A follow-up of a cohort of participants recruited for a prior study will be conducted. In the prior study, 10-18 years olds were provided one of two treatments to improve the sleep of adolescent night-owls.
- Trial name
- NCT05098782
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Vitamin D Deficiency, Metabolic Syndrome
Vitamin D Supplementation and Metabolism in Vitamin D Deficient Elderly
The purpose of this study is to examine the effects of Vitamin D supplementation on the reasons (mechanisms) underlying the development of type 2 diabetes, metabolic syndrome (high blood pressure, cholesterol, diabetes, body…
- Trial name
- VitD (NCT01145703)
- Testing
- RDA Vitamin D3 only, Vitamin D2/3 Repletion only, Vitamin D2/3 Repletion + AEX
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Obesity, Cognitive Disorder
Emotional Regulation, Cognition, Impulsivity and Reward System in Obesity: A Prospective Study of Bariatric Surgery
This research investigates obesity and associated psychiatric symptoms and disorders in a wide range of perspectives, to demonstrate the effects of obesity on the brain.
- Trial name
- NCT03528044
- Testing
- Bariatric surgery
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Koç University