Clinical trials: Cognitive Training
Aging, Social Isolation
HARP-Project 1 Cognitive Training
Emerging evidence from social neuroscience suggests that prefrontal cortex (PFC), insular and anterior cingulate cortex (ACC) regulate social and emotional responses to acute threats to social connectedness among young adults.
- Trial name
- NCT03293823
- Testing
- VSOP training, MLA control
- Where
- 4 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Multitasking Behavior and Neural Representations Associated With Multitasking Ability, Healthy Volunteers
Cognitive Control & the Functional Organization of the Frontal Cortex
The goal of this basic experimental clinical trial is to understand the effect of multitasking practice on the structure of neural representations of tasks in the human lateral prefrontal cortex and control brain regions.
- Conditions
- Multitasking Behavior and Neural Representations Associated With Multitasking Ability, Healthy Volunteers, Executive Function
- Trial name
- NCT06436209
- Testing
- Multitask Practice Intervention (MPI), Single-task Practice Intervention (SPI)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brown University
Depressive Disorder, Major, Treatment Resistant Depression
Stepped Care AiTBS 2 Depression Study (Ghent)
Antidepressant-free unipolar melancholic depressed patients (at least stage 2 treatment-resistant) will be selected by a certified psychiatrist, who will administer (semi-)structured clinical interviews.
- Conditions
- Depressive Disorder, Major, Treatment Resistant Depression, Melancholia
- Trial name
- aiTBS2-Ghent (NCT03288675)
- Testing
- aiTBS, CCT, SSRI
- Where
- Belgium
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Cognition
D2D Normative Data for Remote Assessments
Phase 1: This is a remote observational study in which participants will complete cognitive assessments developed by Posit Science.
- Trial name
- NCT03206775
- Testing
- Cognitive Assessments (Phase 1), Cognitive Battery A (Phase 2), Cognitive Battery B (Phase 2)
- Where
- 2 sites in United States
- Volunteers
- 1,271 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Alzheimer's Disease, Mild Cognitive Impairment
Brain-Computer Interface System for Training Memory and Attention in Elderly
The primary objective is to examine the efficacy of 8-weeks of a locally developed brain-computer interface based system intervention for improving attention and memory in healthy elderly and those with age related cognitive…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Age-Related Cognitive Decline, Dementia
- Trial name
- NCT02228187
- Testing
- Brain-Computer Interface
- Where
- Singapore
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Mild Cognitive Impairment
Cognitive Screening and Cognitive Training in Seniors
This study will provide cognitive screenings for seniors age 50 and older. It will also investigate the benefits of two different cognitive training programs for seniors who have lower baseline performance on memory and/or gist…
- Trial name
- NCT02588209
- Testing
- Strategic Memory Advanced Reasoning Training, Brain Health Workshop
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Cognitive Change
Moderators and Mediators of Perceptual Learning
This is a research study about how training can impact performance on cognitive tasks. Participants are between 18 and 30 and 60 to 85 years of age, have normal (or corrected to normal) vision, and have no neurological conditions…
- Trial name
- NCT05894967
- Testing
- C1 - Standard Perceptual Learning (SPL), C2 - Long Training (LT), C3 - Short Staircases (SS)
- Where
- 3 sites in United States
- Volunteers
- 1,140 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Post-Concussion Syndrome, Post-Traumatic Headache
Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology
The purpose of this study is to compare a 4-week, moderately intensive, lab and home-based aerobic exercise program versus exercise plus cognitive training.
- Conditions
- Post-Concussion Syndrome, Post-Traumatic Headache, Post-Concussive Syndrome, Chronic, Head Injury
- Trial name
- NCT03674398
- Testing
- Exercise+CT, Exercise only
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Healthy
Structure Learning Training and Cognitive Flexibility
The overarching aim of the project is to assess whether structure learning is an effective tool to train and improve cognitive flexibility and whether this is transferable to learning and other cognitive skills.
- Trial name
- NCT05611788
- Testing
- Structure Learning Training
- Where
- Singapore
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Anxiety Symptoms
Effect of IATP on Cognitive Functioning in Anxious Older Adults.
Older adults with anxiety symptoms was found to be associated with greater risk of dementia. Interventions targeting signs as early as in the pre-symptomatic phase could be most effective in early prevention of dementia.
- Trial name
- NCT04413513
- Testing
- Integrated Attention Training Program (IATP), Health Education
- Where
- Hong Kong
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Parkinson's Disease with Cognitive Impairment, Healthy Elderly
Effectiveness of Attention/executivefunctions Training on Prospective Memory Abilities of Parkinson's Disease Subjects with Mild Cognitive Impairment and Healthy Aged Individuals: a Placebo-controlled Study with a Combined Immersive Virtual Reality and Telemedicine Approach
The goal of this randomized controlled trial is to evaluate the efficacy of attention and executive function training on prospective memory (PM) and executive functions in patients with Parkinson's disease and mild cognitive…
- Trial name
- NCT06801782
- Testing
- Experimental Cognitive training in Immersive Virtual Reality and Telemedicine approach, Active Comparator #1
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Alexithymia, Anxiety
Group Skills Training (DBT vs CBT) for Alexithymia in Young Adult Women
This pilot randomized controlled trial examined whether group skills training based on Dialectical Behavior Therapy (DBT) and Cognitive Behavioral Therapy (CBT) can reduce alexithymia (difficulty identifying and describing…
- Conditions
- Alexithymia, Anxiety, Interpersonal Problems, Emotion Regulation
- Trial name
- NCT07865494
- Testing
- DBT-based Group Skills Training (DBT-GST), CBT-based Group Skills Training (CBT-GST)
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Atlas University
Injury;Sports
Neuromuscular Cognitive Training
This project will utilize a quasi-experimental, multiple baseline pretest-posttest design where participants will complete postural stability assessments, physical performance assessments, and questionnaires to evaluate…
- Trial name
- I-THINC (NCT05459363)
- Testing
- I-THINC
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ke'La H Porter
Mild Cognitive Impairment, Exercise Training
Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults
In this research, a unique "Exergame" has been developed and is being tested. The Exergame consists of unique Virtual Reality Cognitive Training (VRCT) games combined with concurrent cycling on a recumbent stationary cycle.
- Trial name
- Exergames (NCT04311736)
- Testing
- Exergame, Cycling, Stretching
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Moai Technologies LLC
Working Memory, Inhibitory Control
BID WM Digital Intervention in Aging
The goal of this clinical trial is to learn if engaging with an digital intervention may improve cognitive function. The main questions it aims to answer are: 1.
- Conditions
- Working Memory, Inhibitory Control, Mild Cognitive Impairment (MCI), Aging
- Trial name
- NCT06918704
- Testing
- Coherence, Worder
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gait Disorder
Cognitive Training and Dual-task Ability
The first goal of this study is to examine the extent to which the inclusion of dual-task practice to standard balance rehabilitation results in greater benefits to dual-task ability.
- Trial name
- NCT01895608
- Testing
- Balance rehabilitation + dual-tasking, Standard balance rehabilitation, Cognitive training (speed of processing)
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety, Anxiety Disorders and Symptoms
Video Game Play to Alleviate Adolescent Anxiety
Adolescence is a critical period for the onset and maintenance of anxiety disorders, which raises the importance of intervening early; one possibility of doing so is via digital interventions.
- Trial name
- NCT05923944
- Testing
- Eco-Rescue, Bejelewed 3
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Sport Medicine
Effects of Rhodiola Rosea Supplementation on Mental Fatigue, Visuo-cognitive Processing, and Strength Performance
This document aims to provide information to request authorization to collect data on the effects of supplementation administered 30 minutes before resistance training on the number of repetitions, execution speed, and perceived…
- Trial name
- Rhodiola Rosea (NCT06853600)
- Testing
- Rhodiola Rosea Capsules
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Obesity, Cognitive Ability, General
Physical Activity and Intermittent Exercise Training for Cardiovascular and Cognitive Gain in Obese Women
One hundred participants from a combination of (a) local advertisements and/or (b) those whose details are held on a research database (of previous volunteers indicating willingness to be contacted about future studies) will be…
- Conditions
- Obesity, Cognitive Ability, General, Cardiovascular Disease
- Trial name
- NCT02853279
- Testing
- Interval exercise training, Continuous exercise training (CON)
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Leeds