Clinical trials: Cognitive-Behavior Treatment
Depression
Learning Through Play (LTP) Plus Intervention for Depressed Fathers (LTP Plus Dads)
The aim of the study is to evaluate the clinical and cost effectiveness of culturally adapted group parenting intervention delivered by non-specialists and community health workers for depressed fathers.
- Trial name
- LTP+Dads (NCT03564847)
- Testing
- LTP Plus
- Where
- 2 sites in Pakistan
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Depression
Efficacy of a Culturally Adapted Cognitive Behavioural Internet-delivered Treatment for Depression
The study seeks to evaluate the efficacy of a culturally adapted internet-delivered treatment for depression in Colombia. The research involves two studies: (a) the cultural adaptation of the Space from Depression…
- Trial name
- CAiCBT (NCT03062215)
- Testing
- Space from Depression
- Where
- 2 sites in Colombia
- Volunteers
- 127 people
- Sponsor
- Silver Cloud Health
Well-Being, Psychological
Virtue-Based vs. Cognitive-Behavioral Interventions in Patients With Chronic Medical Disease
The aim of this study is to analyze the specific and common mechanisms of change of two active treatments, one based on reducing barriers -Cognitive Behavioral Therapy (CBT)- and the other based on enhance resources -Virtue-Based…
- Trial name
- NCT06501235
- Testing
- Cognitive-Behavioral Therapy (CBT), Virtue-Based Intervention (VBI)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Valencia
Eye Movement Desensitization and Reprocessing, Cognitive Behavioral Therapy
RCT Comparing EMDR and CBT for Treatment of Resistant Depression
Depression is one of the most common invalidating mental disorders, ranked by World Health Organization as the single largest contributor to global disability.
- Conditions
- Eye Movement Desensitization and Reprocessing, Cognitive Behavioral Therapy, Neurobiological Processing, Depression
- Trial name
- NCT03972033
- Testing
- EMDR, CBT
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- University of Turin, Italy
Hematologic Cancer, Hematologic Malignancy
Intervention for Fatigue in HCT Recipients
The purpose of this study is to assess whether a cognitive-behavioral therapy (CBT) for fatigue intervention is acceptable, feasible, and effective at managing fatigue and improving quality of life for patients following…
- Trial name
- NCT05715047
- Testing
- CBT for Fatigue, Usual Care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Massachusetts General Hospital
Irritable Bowel Syndrome (IBS)
Feasibility of an Online Cognitive Behavioural Therapy Application (Mahana IBS™, Mahana Therapeutics) in the Management of Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a very common condition where patients suffer from recurrent episodes of tummy pain associated with the way the bowel works (either constipation, diarrhoea, or a mix of both).
- Trial name
- MahanaPilot (NCT07008404)
- Testing
- online cognitive behavioral therapy
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Mild Cognitive Impairment (MCI), Cognitive Training
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial
Effective, clinically meaningful treatments are lacking for patients with mild cognitive impairment (MCI), which is associated with increased risk of transition to dementia.
- Trial name
- COGIT-2 (NCT06601933)
- Testing
- Cognitive Training
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- Columbia University
Substance Use, Substance Use Disorders
Developing a Telehealth Model to Improve Treatment Access for Rural Veterans With Substance Use Disorders
This project will pilot-test and obtain stakeholder input on a telehealth-delivered substance use disorder (SUD) care model (with initial engagement and ongoing MI-CBT treatment) with the goal of increasing treatment utilization…
- Conditions
- Substance Use, Substance Use Disorders, Substance Dependence, Veterans
- Trial name
- VetReach (NCT05348317)
- Testing
- VetReach
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- VA Office of Research and Development
Primary Insomnia
The Role of Partial Reinforcement in the Long Term Management of Insomnia
The lack of scientific attention devoted to the placebo effect as a phenomenon in its own right probably reflects the paucity of theoretical positions within which to organize the existing data and design new research.
- Trial name
- ADER (NCT00662155)
- Testing
- Zolpidem
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of Pennsylvania
Psychotic Disorders, Stress Disorders, Traumatic
Psychotherapy for Psychosis, Adverse Events, and Substance Misuse
People with psychosis have significantly higher rates of adversity (e.g., abuse) and substance misuse (i.e., problematic drug and alcohol use) than people with other mental illnesses.
- Conditions
- Psychotic Disorders, Stress Disorders, Traumatic, Substance Use
- Trial name
- NCT04546178
- Testing
- Prolonged exposure (PE)+ therapy, Treatment as usual (TAU)
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Nova Scotia Health Authority
Schizophrenia, Schizoaffective Disorder
Improving Adherence to Oral Antipsychotic Medications in People With Schizophrenia
This study will determine the comparative effectiveness of two systems designed to improve medication adherence in people with schizophrenia.
- Trial name
- NCT00406718
- Testing
- Med-eMonitor, PharmCAT, Treatment as Usual
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Psychiatric Disorder
Cognitive Model for Behavioral Interventions as a Personalized Intervention for Patients With Serious Mental Illness
The aim of this clinical study is to investigate whether CoMBI-SMI helps to reduce behavioral problems and psychiatric complaints in Serious Mental Illness (SMI) populations complaints and to reduce the burden on informal…
- Trial name
- NCT05820360
- Testing
- CoMBI-SMI
- Where
- Netherlands
- Volunteers
- 94 people
- Sponsor
- Vrije Universiteit Brussel
Chronic Pelvic Pain Syndrome
Efficacy of Cognitive Behavior Therapy for Treatment of Chronic Pelvic Pain in Women
The study will employ 4 treatment arms and 1 placebo arm to compare efficacy of CBT, PFT, Pharmacotherapy, Integrated CBT and PFT modalities in the management of chronic pelvic pain in women.
- Trial name
- NCT07042555
- Testing
- CBT-cp, Pelvic Floor Therapy, Pharmacotherapy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Islamia University of Bahawalpur
Obsessive-compulsive Disorder
Booster as an Adjunct to Internet-based Cognitive Behavior Therapy (CBT)
In this trial, we test if adding an Internet-based booster program to regular Internet-based cognitive behavior therapy (ICBT) is effective for patients with obsessive-compulsive disorder (OCD).
- Trial name
- NCT01525576
- Testing
- Booster
- Where
- Sweden
- Volunteers
- 98 people
- Sponsor
- Karolinska Institutet
Hoarding Disorder
In-home Decluttering Augmentation of Group CBT for HD
The primary aim of trial is to determine the clinical efficacy of in-home decluttering augmentation of group CBT for reducing hoarding severity in adults with HD. The trial takes place in Sweden.
- Trial name
- NCT04712474
- Testing
- In-home decluttering practice
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Bipolar Disorder, Sleep Problems
Brief Sleep Intervention for Bipolar Disorder
Individuals with bipolar disorder (BD) experience extreme mood swings, or episodes of depression and (hypo)mania. These episodes are associated with poor functioning, worse course of illness, and high rates of suicidality.
- Conditions
- Bipolar Disorder, Sleep Problems, Suicidal Thoughts
- Trial name
- NCT01764074
- Testing
- Brief Sleep Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer
Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery
This study will primarily identify longitudinal associations between cardiorespiratory fitness (CRF) and cognitive function pre- (baseline) to post-chemotherapy (~3 months). This will be a prospective study of 50 BCS.
- Trial name
- NCT04616300
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Toronto
Obsessive-Compulsive Disorder (OCD)
A Digital Mindfulness-Based Program for OCD
Obsessive-Compulsive Disorder (OCD) is a common long-lasting, and disabling condition, affecting 1 in every 25 people in Portugal.
- Trial name
- MBCT-OCD (NCT07871344)
- Testing
- Mindfulness-based cognitive-behavioral therapy digital program
- Volunteers
- 128 people
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Insomnia, Sleep Disturbance
A Stepped Care Model to Deliver CBT-I in Community
Insomnia is one of the most common sleep disorders and affects approximately 10 - 40% of the population across different age groups in Hong Kong.
- Trial name
- NCT06109363
- Testing
- Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- Hong Kong
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Depressive Disorder, Depression
Telephone Administered Psychotherapy for the Treatment of Depression for Veterans in Rural Areas
The purpose of this study is to examine the efficacy of telephone-administered cognitive-behavioral therapy (T-CBT) in treating major depression among veterans served by community-based outpatient clinics (CBOCs) in the Veteran's…
- Trial name
- NCT00223652
- Testing
- Telephone cognitive behavioral therapy
- Where
- 3 sites in United States
- Volunteers
- 85 people
- Sponsor
- US Department of Veterans Affairs
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