Clinical trials: Colo-rectal Cancer
Colon Cancer, Rectal Cancer
Assessing Effect of Withdrawal Time on Adenoma Detection Rate for Screening Colonoscopy
The investigators' null hypothesis is that a withdrawal time of 9 to 10 minutes is non-inferior to a withdrawal time of 12 minutes or greater.
- Conditions
- Colon Cancer, Rectal Cancer, Colorectal Cancer
- Trial name
- NCT05018325
- Testing
- Colonoscopy with 6 minute withdrawal, Colonoscopy 9 minute withdrawal, Colonoscopy 12 minute withdrawal
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Colon Cancer, Rectal Cancer
GI SPORE Colon Biosample Protocol
The investigators are creating a data and specimen repository to study causes , early detection, prevention and treatment of colon and rectal cancer.
- Trial name
- NCT02243267
- Testing
- sample collection
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colorectal Disorders, Regional Anesthesia Morbidity
Transversus Abdominis Plane Blocks With and Without Dexamethasone
Dexamethasone will be used as an adjunct to local anesthetics (bupivacaine) to prolong the duration of laparoscopically-placed transversus-abdominis plane blocks in elective colorectal resection.
- Conditions
- Colorectal Disorders, Regional Anesthesia Morbidity, Analgesia, Local Anesthetic Complication
- Trial name
- TAP-DEX (NCT05432934)
- Testing
- Dexamethasone
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Breast Cancer, Cervical Cancer
A Telephone-Based Prevention Care Manager in Increasing Screening Rates for Breast Cancer, Cervical Cancer, and Colorectal Cancer in Minority and Low-Income Women
RATIONALE: Studying the barriers that prevent minority and low-income women from undergoing cancer screening, and offering encouragement to them over the telephone, may help improve cancer screening rates.
- Conditions
- Breast Cancer, Cervical Cancer, Colorectal Cancer
- Trial name
- NCT00376909
- Testing
- educational intervention, study of socioeconomic and demographic variables
- Where
- 2 sites in United States
- Volunteers
- 2,729 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Colorectal Cancer
Folate-Depleted Diet Compared With Folate-Supplemented Diet in Preventing Colorectal Cancer in Patients at High Risk for Colorectal Cancer
RATIONALE: Chemoprevention therapy is the use of certain agents to try to prevent the development of cancer. The use of folic acid may be effective in preventing colorectal cancer.
- Trial name
- NCT00096330
- Testing
- dietary intervention, folic acid
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Colorectal Cancer
Promoting CRC Screening in an Urban Minority Population
The purpose of this study (Healthy Colon Project II) is to evaluate different educational approaches for increasing rates of colorectal cancer (CRC) screening in a hard-to-reach urban minority population with health insurance.
- Trial name
- NCT02392143
- Testing
- Printed Education Material, Academic Detailing, Academic Detailing+Telephone Education
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Colorectal Cancer Screening
Large-Scale Implementation of a Decision Aid About Colorectal Cancer Screening
The goal of the project is to improve shared decision making and increase uptake of colorectal cancer (CRC) screening by facilitating the implementation of a decision aid about CRC and screening options in two healthcare systems…
- Trial name
- IDecide (NCT06597955)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Indiana University
Breast Carcinoma, Colorectal Carcinoma
Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting
This trial assesses current biomarker testing practices for common solid cancers in precision oncology in the community setting.
- Conditions
- Breast Carcinoma, Colorectal Carcinoma, Community Practice, Lung Carcinoma
- Trial name
- NCT03804255
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Colorectal Cancer
A Comparison of Methods to Detect Polyps During Colonoscopy
Colorectal cancer (CRC) is the third most common cancer and second leading cause of cancer deaths in western countries. Colonoscopy is a preferred colorectal screening modality since it has both diagnostic and therapeutic…
- Trial name
- NCT01025960
- Testing
- Standard Inspection Colonoscopy, Dual Inspection Colonoscopy
- Where
- United States
- Volunteers
- 768 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Colorectal Cancer
Colon Cancer Prevention Study
The goal of this research study is to design messages which can help people learn more about how to prevent colon cancer. Eligible participants will be asked to review a series of short cancer prevention messages and share their…
- Trial name
- NCT00924690
- Testing
- Behavioral Messages, Generic Messages
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cancer Colorectal
Evaluation of Letters Promoting Colorectal Cancer Testing
In this evaluation, 4 different versions of letters are being sent with mailers promoting colorectal cancer screening with an at-home test.
- Trial name
- NCT04548765
- Testing
- Letter, Loss Frame and Fear Appeals, Transparency
- Where
- United States
- Volunteers
- 14,644 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Colorectal Cancer, Colorectal Neoplasms
Early Onset Colorectal Cancer Detection
Colorectal cancer (CRC) once predominantly affected older individuals, but in recent years has witnessed a progressive increase in incidence among young adults.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I
- Trial name
- ENCODE (NCT06342401)
- Testing
- ENCODE
- Where
- 13 sites in United States, Italy and 2 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colorectal Neoplasms
Comprehensibility of Colorectal Cancer Screening Educational Materials: Effects on Patient Knowledge and Motivation
The purpose of this study is to determine whether a newly developed patient education document concerning colorectal cancer screening will be better understood and have greater effects on patient knowledge of and motivation for…
- Trial name
- NCT00965965
- Testing
- New colorectal cancer screening patient education document, Traditional colorectal cancer screening education document
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Colorectal Cancer
The FLU-FOBT Program in Primary Care Settings Where Disparities Persist
The investigators overall goals are to adapt, implement, evaluate, and disseminate the FLU-FOBT Program as an integrated nurse-run, primary care-based intervention that can reduce colorectal cancer screening disparities in…
- Trial name
- NCT01211379
- Testing
- FLU-FOBT Program
- Where
- United States
- Volunteers
- 1,372 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Colorectal Cancer
Improving Colorectal Cancer Screening in Racially Diverse Zip Codes Using Navigation and Machine Learning (PCSNaP)
The overarching goal of the "PCSNaP" Research Study is to support the Abramson Cancer Center (ACC) of the University of Pennsylvania in carrying out its mission to increase colorectal cancer (CRC) screening completion among…
- Trial name
- PCSNaP (NCT05383976)
- Testing
- Machine Learning Algorithm with Existing Penn Medicine CRC Patient Navigation Program
- Where
- United States
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Colorectal Cancer
Colorectal Inflammatory Response to a Western-Style Diet
The investigators are involved in a research program to understand how different diets may affect the risk of colorectal polyps and cancer.
- Trial name
- NCT00932308
- Testing
- Western-style diet (WD), Prudent Diet (PD)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Colorectal Cancer
Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization
The goal of this interventional study is to create and test a comprehensive and low burden text message program within existing Community Health Centers (CHC) electronic records system to encourage patients to complete at home…
- Trial name
- CoSMMO (NCT07569250)
- Testing
- Personalized Text Message, Screening Concerns Text Message, Message Framing Text Message
- Where
- 4 sites in United States
- Volunteers
- 7,220 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Colorectal Neoplasms, Colorectal Cancer
Effectiveness of an Integrated Colorectal Cancer Screening in Saudi Arabia: A Pragmatic Randomized Trial
The global burden of colorectal cancer (CRC) incidence among young age groups is rising and overwhelming. This new trend of young-onset CRC incidence is evident in western countries.
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Colonic Polyp, Occult Bleeding
- Trial name
- CRCScreen (NCT04875793)
- Testing
- Stool for Occult Blood Test and Colonoscopy with comprehensive medical checkups
- Where
- Saudi Arabia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Tabuk
Colon Cancer, Breast Cancer
SurgicAl Metabolic Phenotyping Longitudinal Evaluation Study
This work will use a new approach to measure how surgery effects human biochemistry and metabolism. It will create a metabolic signature or 'phenotype' for surgical injury that will help clinicians choose the right surgical…
- Conditions
- Colon Cancer, Breast Cancer, Trauma, Inflammatory Bowel Disease
- Trial name
- SaMPLE (NCT01378013)
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pancreatic Cancer, Breast Cancer
The Clinical Application Value of SPECT Imaging Targeting LRRC15 in Malignant Tumors
Here's a polished version of the text: "This project involves patients with high-expression LRRC15 malignant tumors who are either clinically suspected of or diagnosed with pancreatic cancer, breast cancer, lung cancer, ovarian…
- Conditions
- Pancreatic Cancer, Breast Cancer, Lung Cancer, Sarcoma
- Trial name
- NCT07651020
- Testing
- Specific SPECT imaging agents targeting LRRC15
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology