Clinical trials: Colo-rectal Cancer
Colorectal Cancer
Traditional Print Communication Methods, Simple Electronic Communication Methods, or Usual Care in Increasing How Often Older Women Undergo Colorectal Cancer Screening
RATIONALE: Finding out which communication method affects a participant's decision to undergo colorectal cancer screening may help increase the number of participants who undergo screening.
- Trial name
- NCT00459030
- Testing
- educational intervention via internet, educational intervention mailed, No additional educational intervention
- Where
- United States
- Volunteers
- 904 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Colorectal Adenoma and Carcinoma
Investigation of the Role of the Microbiome in the Pathogenesis of Colorectal Adenoma and Carcinoma
The purpose of this study is the investigation of new host-microbiome interactions promoting adenoma formation and adenocarcinoma progression.
- Trial name
- NCT02947607
- Testing
- Colon biopsies
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 799 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colo-rectal Cancer, Anesthesia
Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery?
This study is a randomized, double blind controlled trial examining the impact of incorporating a single intraoperative intravenous magnesium bolus and infusion into a preexisting Enhanced Recovery After Surgery (ERAS) protocol…
- Trial name
- NCT05021263
- Testing
- IV Medications
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Early Diagnosis of Colorectal Cancer and Adenoma
Correlation Between SFRP1 and Colorectal Cancer and Adenoma
In summary, our study demonstrated the methylation sites of SFRP1 gene promoter in patients with colorectal cancer and adenoma and found SFRP1_16_17_18 CpG site was good performance as a diagnostic marker of colorectal cancer.
- Trial name
- NCT05204433
- Testing
- no intervention
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Colorectal Cancer
Promoting Colorectal Cancer Screening in Rural Emergency Departments
This trial will compare the effects of a culturally targeted intervention designed to assist participants to identify and overcome individual barriers to colorectal cancer (CRC) and to promote CRC screenings using motivational…
- Trial name
- NCT03473587
- Testing
- Motivational interview, Standard of care
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Cervical Cancer Screening, Breast Cancer Screening
Social Media-Based Education on Cancer Screening Awareness in Women: A Randomized Controlled Trial
This randomized controlled study evaluated a social media-based educational program for women who had not previously participated in breast, cervical, or colorectal cancer screening.
- Conditions
- Cervical Cancer Screening, Breast Cancer Screening, Colorectal Cancer Screening, Digital Health Literacy
- Trial name
- NCT06939699
- Testing
- Social Media-Based Education, Standard Online Education
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Emine Ergin
Colorectal Disorders, Colorectal Neoplasms
Comparison of the Left-Lateral Horizontal and Supine Positions for Colonoscopy Intervention: A Randomized Controlled Study
Objective: One of the most common technical difficulties during colonoscopy is passing through the fold of the sigmoid colon. Colonoscopy is commonly performed by endoscopists with the patient in the left lateral position.
- Conditions
- Colorectal Disorders, Colorectal Neoplasms, Colorectal Polyp, Colo-rectal Cancer
- Trial name
- NCT07517848
- Testing
- Colonoscopy after bowel cleansing
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Lung Cancer, Colorectal Cancer
ProSight: A Multi-centre Interventional Study Evaluating MCED in Asymptomatic Population
This is a prospective, multi-centre interventional study evaluating the feasibility of blood-based multi-cancer early detection test in asymptomatic screening cohort.
- Conditions
- Lung Cancer, Colorectal Cancer, Liver Cancer, Grastic Cancer
- Trial name
- NCT06790355
- Testing
- multi-cancer early detection
- Where
- 4 sites in China
- Volunteers
- 2,527 people, healthy volunteers welcome
- Sponsor
- Shanghai Weihe Medical Laboratory Co., Ltd.
Time Restricted Eating, Obesity
Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers
Approximately 42% of American adults are obese, and this condition is strongly related to the development of colorectal cancer. Innovative lifestyle strategies to treat obesity and reduce colorectal cancer risk are critically…
- Conditions
- Time Restricted Eating, Obesity, Weight Loss, Colorectal Cancer
- Trial name
- NCT05114798
- Testing
- Time restricted eating, Calorie Restriction
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cancer Colon
Blood-Based Colorectal Cancer (CRC) Screening Implementation Into Clinical Practice Highlands
This is a prospective implementation study that will include patients that are identified as being average risk for colorectal cancer (CRC) according to USPSTF guidelines and who have opted to be screened for CRC.
- Trial name
- NCT06119425
- Testing
- blood-based CRC screening
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Ballad Health
Colorectal Cancer
Vitamin D Intervention and Associated Changes in the Gut Microbiome and Vitamin D Levels in Healthy Adults
Although dietary vitamin D supplementation has been used in the clinical setting for decades, the effect of supplementary vitamin D consumption on the structure of the microbiome has not been studied in humans in fine scale or…
- Trial name
- VDMT (NCT05387876)
- Testing
- Vitamin D intervention
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Baylor University
Colorectal Cancer Screening
Bowel Preparation in Colonoscopy: Lactulose vs Polyethyleneglycol, Randomized Double-blind Comparative Clinical Trial, Multicenter Study.
The goal of this clinical trial it is to bowel the instestinal preparation with lactulose vs poliethylenglicol as better agent to have a quality colonoscopy and demostrate that lactulose is most efective, has a good tolerance and…
- Trial name
- NCT06666556
- Testing
- Bowel preparation before colonoscopy
- Where
- 3 sites in Mexico
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- Hospital Civil de Guadalajara
Colorectal Cancer
Dissemination of Colorectal Cancer Screening to Primary Care Physicians
The aim is to assess the efficacy of an intervention, academic detailing, a brief, frequently repeated educational program, on increasing recommendations for colorectal cancer screening among primary care providers by comparison…
- Trial name
- NCT00441311
- Testing
- Academic Detailing
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Columbia University
Colorectal Cancer, Colorectal Cancer Metastatic
Possible Association of Intestinal Helminths and Protozoa With Colorectal Cancer Pathogenesis
Colorectal cancer (CRC) has the third highest cancer incidence in the world. There is mounting evidence that the intestinal microbiota plays an important role in colorectal carcinogenesis.
- Conditions
- Colorectal Cancer, Colorectal Cancer Metastatic, Intestinal Parasite, Protozoan Infections
- Trial name
- NCT03173001
- Testing
- Parasitological examination
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan
Colorectal Cancer
Does Knowing One's Estimated Colorectal Cancer Risk Influence Screening Behavior?
This study is designed to examine the impact of telephone-based colorectal cancer risk assessment on colorectal screening attitudes and behavior among previously unscreened adults ages 50 to 75.
- Trial name
- NCT03819920
- Testing
- Risk Assessment (CCRAT), Usual Care (UC)
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colorectal Cancer Screening, Cervical Cancer Screening
Multilevel Intervention Based on Colorectal Cancer (CRC) and Cervical Cancer Self-screening in Rural, Segregated Areas
In this study, the investigators will deliver self-sampling human papillomavirus (HPV) tests and fecal immunochemical test (FIT) kits, as well as adapted cancer screening educational materials, by mail to 110 women who are…
- Trial name
- NCT04471194
- Testing
- Self-sampling HPV test, Fecal occult blood test
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
No Condition
Effectiveness of SMS Invitation on Colorectal Cancer Screening on 45-49-Year-Olds
The goal of this study is to learn if sending text message invitations increases participation in colorectal cancer screening among 45-49 year olds in Yingge District, New Taipei City.
- Trial name
- SMS (NCT07112729)
- Testing
- Active SMS Invitation
- Where
- Taiwan
- Volunteers
- 6,708 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Colonic Polyps
GENESIS: Genetic Biopsy for Prediction of Surveillance Intervals After Endoscopic Resection of Colonic Polyps
Colorectal cancer ist the 2nd most leading cancer among men and women in germany. Screening colonoscopy has the potential to detect premalignant lesions.
- Trial name
- GENESIS (NCT02595645)
- Testing
- Polypectomy and NGS
- Where
- 4 sites in Austria, Germany
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Colorectal Cancer, Colorectal Neoplasms
Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia
The investigators aim to evaluate and compare the diagnostic accuracy of FIT and the novel panel of bacterial gene markers (Fn, m3, Ch and Bc) collectively named as M3, in detecting colorectal advanced neoplasia.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenoma
- Trial name
- M3-PRO (NCT05405673)
- Testing
- Fecal immunochemical test (FIT)
- Where
- Hong Kong
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer
The Roles of Exosomal Circ-LRBA and 451/CRTC2 Signaling Axis in Colorectal Cancer
Colorectal cancer (CRC) is one of the most common malignant tumors in the world. Most of the patients with colorectal cancer were diagnosed in poor stage.
- Trial name
- NCT05579353
- Testing
- nothing
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jingbo Chen