Clinical trials: Colon Adenoma
Adenoma Colon, Polyp of Colon
Computer-aided Detection of Colorectal Polyps
In this observational pilot study, we assess the diagnostic performance of an artificial intelligence sytem for automated detection of colorectal polyps.
- Trial name
- NCT04359355
- Testing
- Artificial Intelligence System for Detection of colorectal polyps
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Adenoma, Colo-rectal Cancer
Clinical Value of G-EYE Colonoscopy in Daily Practice for Adenoma Detection and Time for Polyp Removal
Colonoscopy parameters will be compared before the introduction of the G-EYE endoscope and after the introduction of the G-EYE endoscope
- Trial name
- NCT04767971
- Testing
- Standard Colonoscopy, G-EYE Colonoscopy
- Where
- Germany
- Volunteers
- 2,795 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Ulcerative Colitis, Colorectal Cancer
Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at three time points during ileal pouch…
- Conditions
- Ulcerative Colitis, Colorectal Cancer, Crohn Disease, Familial Adenomatous Polyposis
- Trial name
- NCT04695964
- Testing
- ICG-NIRF Imaging plus ingress and egress analysis
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Colonic Dysplasia, Adenomatous Polyps
Study of Performance of Confocal Endomicroscope With Fluorescein Imaging Agent in the Colon
The overall aim of this research project is to evaluate the imaging performance of a confocal endomicroscope. Fluorescein, an FDA-approved topical fluorescent dye, will be used to provide topical mucosal contrast.
- Conditions
- Colonic Dysplasia, Adenomatous Polyps, Irritable Bowel Disease
- Trial name
- NCT03220711
- Testing
- confocal endomicroscope, Fluorescein
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Michigan
Colorectal Cancer, Screening
ColoAssist vs. MEI
Colonoscopy aims to investigate the entire colon by advancing the colonoscope tip from the rectum to the cecum, a process called cecal intubation.
- Trial name
- NCT01895504
- Testing
- ColoAssist, MEI
- Where
- 2 sites in Norway
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Cancer
E-MOSAIC Electronic Tool to Monitor Symptoms
RATIONALE: A hand held electronic tool used to monitor symptoms and assess quality of life may improve communication between patients and their doctors and improve the ability to plan treatment for patients with advanced cancer…
- Trial name
- NCT00477919
- Where
- 7 sites in Switzerland
- Volunteers
- 264 people
- Sponsor
- Swiss Cancer Institute
Colorectal Cancer
The National CT Colonography Trial
RATIONALE: New diagnostic procedures such as computed tomographic colonography may improve the ability to detect colorectal cancer and may provide a less invasive method of detection.
- Trial name
- ACRIN6664 (NCT00084929)
- Testing
- CT Colonography
- Where
- 14 sites in United States
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- American College of Radiology Imaging Network
Colonoscopy, Gastro-Intestinal Disorder
Video Tutorial and Oral Explanation Vs Oral Explanation Alone in Colonoscopy Preparation
Colonoscopy which is the standard examination for the exploration of the colon and rectum is performed very frequently. Colon preparation before the examination is an essential step and pescription of the colonic preparation is…
- Trial name
- PREPACOTUTO (NCT07355777)
- Testing
- Colonoscopy
- Where
- 5 sites in France
- Volunteers
- 574 people
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Familial Adenomatous Polyposis
Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP)
Background and study aim The relative risks of duodenal adenocarcinoma and ampullary carcinoma in Familial Adenomatous Polyposis (FAP) have been estimated 100 to 330 times higher than in general population.
- Trial name
- NCT02656134
- Testing
- Duodenoscopy and enteroscopy, Molecular analysis.
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Sao Paulo
Colorectal Cancer, Adenoma
Care for Colon 2015
The investigatior believe that implementing camera capsule endoscopy as a filter test to colonoscopy will increase screening participation, increase the number of individuals with detected intermediate- high risk adenomas or…
- Trial name
- CFC2015 (NCT04049357)
- Testing
- Camera Capsule Endoscopy/ PillCam
- Where
- Denmark
- Volunteers
- 2,031 people
- Sponsor
- Odense University Hospital
Adenoma Colon, Colon Adenoma
Conventional Endoscopic Mucosal Resection Versus Cold Snare Endoscopic Mucosal Resection of Colonic Lateral Spreading Lesions - A Randomised Controlled Trial
Comparing the complete resection rate and subsequent adenoma recurrence rate at surveillance colonoscopy of 15-40mm laterally spreading adenomas for conventional EMR vs. cold snare EMR.
- Conditions
- Adenoma Colon, Colon Adenoma, Colon Cancer
- Trial name
- NCT04138030
- Testing
- Conventional Endoscopic Mucosal Resection, Cold Snare Endoscopic Mucosal Resection
- Where
- Australia
- Volunteers
- 182 people
- Sponsor
- Western Sydney Local Health District
Familial Adenomatous Polyposis
The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study
Familial adenomatous polyposis (FAP) leads to adenomas and eventual adenocarcinomas in colon and less frequently, duodenum. Chemopreventive strategies have been studied in FAP patients to delay the development of adenomas and…
- Trial name
- NCT01725490
- Testing
- Metformin
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Yonsei University
Colorectal Cancer, Adenomatous Polyps
Multi-omics Study for Early Detection of Colorectal Cancer (MOED-CRC)
The primary objective of the study is to screen multi-omics markers in blood samples and construct a prediction model for CRC based on liquid biopsy, and we will further optimize the prediction model by validating its clinical…
- Conditions
- Colorectal Cancer, Adenomatous Polyps, Adenoma, Advanced Adenoma
- Trial name
- NCT06220617
- Where
- 6 sites in China
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Bowel Obstruction, Bowel Ischemia
Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at two to three time points during procedures of…
- Conditions
- Bowel Obstruction, Bowel Ischemia, Diverticulitis, Abnormality of the Gastrointestinal Tract
- Trial name
- NCT04709445
- Testing
- ICG-NIRF Imaging plus ingress and egress analysis
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Colorectal Cancer
Case Volume and Adenoma Rate During Screening Colonoscopy
Screening colonoscopy has been established as the most effective means of colorectal cancer prevention. This is based on the fact that colonoscopy detects and removes colonic polyps (adenomas) which are known to progress to…
- Trial name
- NCT00860665
- Where
- Germany
- Volunteers
- 12,134 people
- Sponsor
- Charite University, Berlin, Germany
Colonic Polyp, Colonic Adenoma
Detection Of Colonic Polyps In India: Diagnostic Colonoscopy
Colorectal carcinoma (CRC) is the third most common cancer in male and female worldwide. In India, it is the fourth most common cause of cancer in males and third most common cancer in female.
- Conditions
- Colonic Polyp, Colonic Adenoma, Colonic Neoplasms
- Trial name
- DoCPI (NCT04512729)
- Testing
- Colonoscopy
- Where
- India
- Volunteers
- 4,000 people
- Sponsor
- Asian Institute of Gastroenterology, India
Polyp of Colon
Impact of Artificial Intelligence (AI) on Adenoma Detection During Colonoscopy in FIT+ Patients.
The Italian screening program invites the resident population aged 50-74 for Fecal Immunochemical Test (FIT) every 2 years. Subjects who test positive are referred for colonoscopy.
- Trial name
- AIFIT (NCT04691401)
- Testing
- Artificial Intelligence System (CAD EYE, Fujifilm Co.)
- Where
- Italy
- Volunteers
- 750 people
- Sponsor
- Valduce Hospital
Colon Adenoma, Colorectal Carcinoma
NBI Versus White Light Endoscopy for Optical Characterization of Neoplastic Polyps in the Colorectum
Adenomas, serrated adenomas and hyperplastic polyps are polypoid lesion in the colorectum. At the present moment, all polyps should be resected endoscopically, although only adenomas and serrated adenomas, but not hyperplastic…
- Conditions
- Colon Adenoma, Colorectal Carcinoma, Hyperplastic Polyp, Serrated Adenoma
- Trial name
- ADOPTION II (NCT03679429)
- Testing
- NBI Function
- Where
- 3 sites in Germany
- Volunteers
- 370 people
- Sponsor
- Technical University of Munich
Colorectal Neoplasms, Colorectal Neoplasms Malignant
Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy
Robotic right hemicolectomy with intra-corporeal anastomosis may have better short-term recovery outcomes and decreased incidence of incisional hernia when compared to the laparoscopic actual standard of care, for similar safety…
- Conditions
- Colorectal Neoplasms, Colorectal Neoplasms Malignant, Colorectal Neoplasms, Benign, Colorectal Cancer
- Trial name
- PRORHEM (NCT06067620)
- Testing
- Robotic right hemicolectomy, Laparoscopic right hemicolectomy
- Volunteers
- 70 people
- Sponsor
- Jeremy Meyer
Colonoscopy
Effect of Intraluminal Administration of Menthol Solution During Colonoscopy on Colonic Spasm and Adenoma Detection Rate
In recent years, with increasing research into antispasmodic agents, topical antispasmodics have attracted considerable attention due to their direct action on the gastrointestinal mucosa and relatively low incidence of adverse…
- Trial name
- NCT07501962
- Testing
- Endoscopic irrigation was performed using a 0.1% menthol solution combined with simethicone., Endoscopic irrigation was performed using an aqueous suspension prepared with simethicone and normal saline.
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhengzhou University