Clinical trials: Colon Neoplasm
Breast Cancer, Colorectal Cancer
Population-Based Patient-Centric Care: Comprehensive Preventive Cancer Screening Using Health IT
Although there is considerable evidence that current health IT can improve certain elements of care, the most effective and efficient implementation of health IT systems for primary care population management are not currently…
- Conditions
- Breast Cancer, Colorectal Cancer, Cervical Cancer
- Trial name
- TopCare (NCT01372527)
- Testing
- TopCare: Use of provider knowledge vs. automated system
- Where
- United States
- Volunteers
- 103,870 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colorectal Carcinoma, Advanced Adenomas (AA)
Development and Validation of a Blood Test for Early Diagnosis of Colorectal Cancer
This is a prospective, multicenter, case-control study. The aim is to develop an optimized algorithm by combining the levels of molecular markers in plasma together with risk factors for developing colorectal cancer and clinical…
- Trial name
- ColoDix (NCT06889883)
- Where
- 9 sites in Spain
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- ADVANCED MARKER DISCOVERY S.L.
ColoRectal Cancer
PROSPR Project 1: Identifying and Tracking Personalized CRC Screening Regimens for Patients in Clinical Settings
The overall goal of the Parkland-UT Southwestern Population-based Research Optimizing Screening through Personalized Regimens (PROSPR) Center is to optimize colon cancer screening through personalized regimens in the integrated…
- Trial name
- NCT03705897
- Testing
- Computerized Risk Stratification Tool, Algorithmic Risk Stratification Tool, Step completion assessment
- Where
- United States
- Volunteers
- 9,264 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Lynch Syndrome, Lynch Syndrome I
Videocapsule Endoscopy in Lynch Syndrome
Background Lynch syndrome is caused by a pathogenic variant in one of the four Mismatch Repair genes (MMR): MLH1, MSH2/Epcam, MSH6, or PMS2.
- Conditions
- Lynch Syndrome, Lynch Syndrome I, Lynch Syndrome II, MLH1 Gene Mutation
- Trial name
- NCT05704010
- Testing
- Video capsule endoscopy
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- San Raffaele University
Breast Carcinoma, Cervical Carcinoma
Support Program for Adoption of Cancer Screening Interventions at a Rural Community-Based Organization
This pilot trial study uses a structural support program for adoption of cancer screening interventions at a rural community-based organization.
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma, Malignant Solid Neoplasm
- Trial name
- NCT04208724
- Testing
- Training, Cancer Screening intervention, Survey Administration
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Colorectal Cancer
Chemotherapy-Related Changes in Neurocognitive Function and Symptoms in Colorectal Cancer Patients: A Pilot Study
Cancer treatments have successfully improved cancer outcomes but frequently negatively impact quality of life in cancer survivors.
- Trial name
- NCT03683004
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Colorectal Cancer
Proactive Outreach With FIT
The purpose of the study is to boost colorectal cancer (CRC) screening rates in an underserved population in Brooklyn through organized, proactive outreach of mailed Fecal Immunochemical Tests (FIT), utilizing evidence-based…
- Trial name
- PROOF (NCT06269744)
- Testing
- Proactive Screening Outreach
- Where
- 2 sites in United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colorectal Cancer
The PharmFIT Study
This study will conduct a randomized controlled trial to assess the impact of a pharmacy-based FIT intervention, Pharmacy-based FIT (PharmFIT), on colorectal cancer screening (CRC) screening rates in primary care patients who are…
- Trial name
- PharmFIT (NCT06656936)
- Testing
- PharmFIT
- Where
- 2 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colonic Polyp, Colonic Adenoma
Nationwide Study of Artificial Intelligence in Adenoma Detection for Colonoscopy
The goal of this trial is to determine whether use of a Computer Assisted Detection (CADe) programme leads to an increase in ADR for either units or individual colonoscopists, independent of setting or expertise
- Conditions
- Colonic Polyp, Colonic Adenoma, Colo-rectal Cancer
- Trial name
- NAIAD (NCT05870332)
- Testing
- GI Genius (GIG)
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Colorectal Cancer, Cancer Screening
Small Media Interventions to Increase Colorectal Cancer Screening Among Chinese Americans
There have been few studies of small media interventions to promote colorectal cancer screening among Chinese Americans. Based on the results of strong preliminary studies on the promotion of colorectal cancer screening among…
- Trial name
- SMILES (NCT03174444)
- Testing
- Small Media
- Where
- United States
- Volunteers
- 1,707 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Colo-rectal Cancer, Polyp of Colon
Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm
The focus of the study is to evaluate impact of submucosal injection of EverLift in achieving complete resection during polypectomy of polyps 4-9mm during colonoscopy.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyp of Colon
- Trial name
- NCT04551014
- Testing
- Use of EverLift, Without use of EverLift
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Stanford University
Helicobacter Pylori Infection, Colorectal Cancer
European Implementation Study on Simultaneous Screening for Gastric and Colorectal Cancers
The EUGastScreen study is designed as a quality implementation study to explore gastric cancer screening strategies within organised cancer screening frameworks.
- Conditions
- Helicobacter Pylori Infection, Colorectal Cancer, Gastric Cancer
- Trial name
- EUGastScreen (NCT07873580)
- Testing
- Fecal sample acquisition for Helicobacter pylori stool antigen test, Upper endoscopy with biopsies, Colonoscopy with biopsies after bowel cleansing
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Colorectal Cancer, Colorectal Adenoma
To Investigate Risk of Colorectal Neoplasms in First-degree Relatives of Patients With Non-advanced Adenomas
The risk of CRC in families of patients with CRC is well established, but it is less well-defined for families of patients with adenomas.
- Trial name
- NonAA (NCT02521727)
- Where
- 2 sites in Hong Kong
- Volunteers
- 828 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer, Colorectal Carcinoma
Latinos CARES (Colorectal Cancer Awareness, Research, Education and Screening)
The purpose of this study is to conduct 4 focus groups and recruit for 12 participants per focus group to explore community members' views about colorectal cancer screening (CRCS) processes and perceived benefits and impediments…
- Trial name
- NCT03078361
- Testing
- Immunochemical Fecal Occult Blood Test (I-FOBT) Kit, LATINOS CARES Toolkit, Standard Intervention
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colorectal Cancer, Inflammatory Bowel Diseases
Microbiota-anastomotic Leak Among Colorectal Surgery Patients : Pilot Study
The study is based on the hypothesis that patients with postoperative anastomotic leakage have a different bacterial profile contributing to poor tissue healing, and that patients operated for colon cancer presumably have a…
- Conditions
- Colorectal Cancer, Inflammatory Bowel Diseases, Microbiota, Anastomotic Leak
- Trial name
- NCT03496441
- Testing
- Fecal sample collection for analysis
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Colonic Neoplasms
Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer
The purpose of this study is: to determine neutrophil activity in patients with colon cancer, to determine levels sFas, sFasL and IL - 17 in serum of healthy volunteers and colon cancer patients and establish its prognostic…
- Trial name
- NCT00860691
- Testing
- Therapeutic conventional colorectal surgery, Therapeutic laparoscopic colorectal surgery, Peripheral blood sampling and performing: ELISA test of sFas, sFasL, IL - 17 and Bursttest
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Rectal Cancer, Low Anterior Resection Syndrome
Feasibility and Impact of a Prehabilitation and Rehabilitation Program for the Continuity of Care in Severe Low Anterior Resection Syndrome.
Patients with sphincter saving procedures of rectal cancer usually experience intestinal dysfunction, including difficulty emptying the bowel and faecal incontinence, leading to a detriment in the quality of life.
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, Faecal Incontinence
- Trial name
- PRELARS (NCT04612569)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Donostia
Colorectal Cancer
Trial of a Multilevel Intervention to Increase Colorectal Cancer Screening
This study will assess the effectiveness of a culturally-responsive intervention to increase colorectal cancer (CRC) screening among Latino immigrants in a primary care clinic setting of a large municipal Hospital in New York…
- Trial name
- NCT00836303
- Testing
- Colorecatal Cancer Screening Activation
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cancer Diagnosis, Liver Cancer, Adult
Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis
The goal of this observational study is to explore whether a Raman-based, deep learning-assisted approach can be used to develop an effective method for early pan-cancer screening.
- Conditions
- Cancer Diagnosis, Liver Cancer, Adult, Cancer Screening, Colorectal Cancer (CRC)
- Trial name
- NCT06822413
- Testing
- No Interventions
- Where
- 4 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colon Cancer
Phase I Biomarker Study of Dietary Grape-derived Low Dose Resveratrol for Colon Cancer Prevention
This study is designed to investigate the dietary influence of grapes in colon cancer prevention. A natural compound found in the skin of grapes, resveratrol, may protect against cancer by acting as an antioxidant (a chemical…
- Trial name
- NCT00578396
- Testing
- grapes
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
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