Clinical trials: Colon Neoplasm
Colorectal Cancer
Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk
The overall goal of this study is to develop a comprehensive, culturally tailored community-based colorectal cancer (CRC) prevention model with a dual emphasis on reducing CRC risk along with its CVD risk factors.
- Trial name
- CHURCH (NCT05174286)
- Testing
- SBIRT, Referral as Usual (RAU)
- Where
- United States
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Columbia University
Colorectal Cancer
Colorectal Cancer Screening Navigator Program for Low Income and Non-English Speaking Populations
The goal of this study is to implement and in a controlled randomised trial test a program to identify and overcome barriers to CRC screening and thus improve CRC screening rates at MGH Chelsea HC.
- Trial name
- NCT00476970
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 1,223 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Sigmoid Colon Cancer
The Effects of Mechnikov Probiotics on Symptom and Surgical Outcome
The purpose of this clinical trial study was to evaluate the prevalence of colon cancer among the symptom (s) of anterior resection syndrome that may occur after surgery in patients for efficacy and safety in Metchnik probiotic…
- Trial name
- NCT03531606
- Testing
- Mechnicov probiotics
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Kye Bong-Hyeon
Colorectal Cancer
Effectiveness of Fecal Immunnochemical Test and Colonoscopy Screening in Hong Kong
Colorectal neoplasm in Asia is now increasingly common and is rising in an alarming manner in Hong Kong. Population-based screening for colorectal cancer (CRC) should be implemented.
- Trial name
- NCT03597204
- Testing
- Fecal immunochemical test (FIT), Colonoscopy
- Where
- Hong Kong
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Neoplasms, Cancer
Cancer Experience Registry (CER) for Cancer Patients and Caregivers
The Cancer Experience Registry®: An Online Survey Research Study to Understand the Experiences of Those Impacted By a Cancer Diagnosis. The Registry is a web-based platform to distribute cross-sectional and longitudinal surveys.
- Conditions
- Neoplasms, Cancer, Caregiver
- Trial name
- CER (NCT02333604)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Cancer Support Community, Research and Training Institute, Philadelphia
Colorectal Cancer
Effect of Oral Administration of Methylene Blue MMX Tablets on Double Stranded DNA
Single Centre, open label assignment phase II clinical study. To evaluate the effect of oral 200mg Methylene Blue tablets (administered 8x25mg) prior to endoscopy on double stranded DNA breaks in colonic biopsy samples assessed…
- Trial name
- NCT02295774
- Testing
- Methylene Blue MMX tablets
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cosmo Technologies Ltd
Colorectal Cancer, Somatic (Diagnosis)
Mycotoxin Exposure and Dietary Habits in Colorectal Cancer Prevention and Development Among Polish Population
The aim of the study is the determination of the zearalenone and its metabolites (α and β) level in the blood plasma and faeces of patients at increased risk of cancer, in relation to the nutrition data (FFQ) and information on…
- Trial name
- NCT04152265
- Testing
- colonoscopy, questionnaires, demographic data collections
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury in Olsztyn
Colo-rectal Cancer, Colon Lesion
Compare the Patient Satisfaction and Effectiveness After Novel Application-based or Conventional Health Education of Bowel Preparation for Colonoscopy
Colorectal cancer is the cancer with highest incidence in Taiwan. The disease itself and subsequent treatment cause huge impact on the physical, psychological, and spiritual parts and social role of a patient.
- Trial name
- NCT06560671
- Testing
- novel type of health education
- Where
- Taiwan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer
Head to Head Study Epi proColon and FIT
The study aims to show non-inferiority in the clinical performance of the investigational assay, Epi proColon, to FIT using matched blood and stool specimens from screening-guideline eligible subjects.
- Trial name
- NCT01580540
- Where
- 70 sites in United States, Puerto Rico
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Epigenomics, Inc
Colon Cancer, Colitis
Novel Listeria Vectors Secreting Gut Flora-Altering Agents to Prevent Colon Cancer and Treat Colitis
This is a simple tissue collection study with no therapeutic intent. Colon tissues will be taken from standard of care procedures.
- Trial name
- NCT03014284
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Colorectal Cancer
Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omics
Background: The current screening techniques for colorectal cancer include colonoscopy, fecal occult blood, and high-risk factor questionnaires.
- Trial name
- NCT04913233
- Where
- 3 sites in China
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Cancer
Diet and Physical Activity Program in Colorectal Cancer Survivor: a Randomized Controlled Trial
Colorectal cancers (CRC) represent the 1st digestive cancer and the 3rd cancer in the world. The World Cancer Research Fund summarized evidence from observational studies and concluded that low dietary fiber, and high red and…
- Trial name
- DPAP (NCT06194786)
- Testing
- Group D
- Where
- Tunisia
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Habib Bourguiba University Hospital
Colorectal Cancer Stage II, Colorectal Cancer Stage III
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
This phase III trial evaluates whether a web-based intervention called Current Together after Cancer (CTAC) works to increase the number of patients with surgically removed (resected) colorectal cancer who receive surveillance…
- Trial name
- NCT07018869
- Testing
- Intervention website access, Control website access, Interview
- Where
- 384 sites in United States, Guam and 1 more
- Volunteers
- 1,057 people, healthy volunteers welcome
- Sponsor
- SWOG Cancer Research Network
Colorectal Cancer
A Culturally-adapted Colorectal Cancer Screening Decision Aid Designed for American Indians
Experts note that in order to continue reducing the US cancer burden, it is critical that investigators "more completely apply discoveries in cancer prevention we have already made." Thus, it is important to research strategies…
- Trial name
- NCT03569761
- Testing
- Colorectal Cancer Screening Decision Aid, Control Group
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colorectal Cancer
Ancillary Study of Methylation Biomarkers in a Randomized Controlled Trial of a Personalized Prevention of Colorectal Cancer
Based on the magnesium tolerance test (MTT, "gold standard" for assessing magnesium (Mg) status), it was found that over 50% of participants in the US exhibited Mg deficiency.
- Trial name
- NCT04196803
- Testing
- Magnesium glycinate
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Colorectal Cancer
Screening TO Prevent ColoRectal Cancer (STOP CRC) Among At-Risk Chinese and Korean American Primary Care Patients
The objective of the study is to conduct a randomized controlled trial to determine the impact of a multi-level culturally-sensitive decision support intervention on colorectal cancer screening adherence among 400 Chinese and…
- Trial name
- NCT03481296
- Testing
- Advanced Control, Culturally-Adapted Decision Support Navigation Intervention
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Colonic Neoplasms, Breast Neoplasms
End-of-Life Care for African Americans
Racial differences in health care are documented across the health care continuum and persist in aging and end-of-life (EOL) care.
- Conditions
- Colonic Neoplasms, Breast Neoplasms, Lung Neoplasms
- Trial name
- NCT02320123
- Testing
- Educational DVD
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Colo-rectal Cancer
A Patient-centered Intervention Using Technology to Reduce Colorectal Cancer Disparities in Primary Care
The purpose of this proposal is to test the efficacy of a patient-centered, tailored message intervention delivered via virtual technology for increasing colorectal cancer (CRC) screening within guidelines among racial/ethnic…
- Trial name
- NCT03407417
- Testing
- virtual technology
- Where
- 2 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Florida
Colorectal Cancer
Effects of Weight on Inflammation and Colon Cancer Risk
An observational study designed to compare colonic cytokine concentrations in lean versus obese individuals
- Trial name
- NCT02884024
- Testing
- no intervention
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Tufts University
Colorectal Neoplasms
Internet-Based Motivational Interviewing for Colonoscopy
Compared to other racial groups, African Americans have the highest colorectal cancer (CRC) morbidity and mortality rates. Although colonoscopies can prevent CRC, nearly one third of African Americans have not received a…
- Trial name
- NCT03595904
- Testing
- E-Motivate group, Usual Care Group
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai