Clinical trials: Colon Neoplasms
Adenoma, Bile Duct
The Effects of An Addition of Water Enema to PEG for Colon Preparation
The purpose of this study is to compare the preparation quality by using Ottawa Bowel Preparation Scale between the standard PEG preparation and the addition of water enema in participants scheduled for CRC screening
- Trial name
- NCT03270046
- Testing
- Water enema
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Colorectal Adenoma, Colorectal Polyp
EndoRings Colonoscopy vs Standard Colonoscopy
The study aims to compare the results between a standard colonoscopy to a colonoscopy with an attachment on the distal end of the colonoscope.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colon Cancer
- Trial name
- NCT03418662
- Testing
- EndoRings device
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cancer, Lung, Cancer, Breast
Early Detection of Five Common Cancers Using the ctDNA Analysing Test
This is a multi-centre, prospective cohort study, aiming to evaluate a blood test in early detection of the four common cancers, based on the investigation of the circulating tumour DNA (ctDNA).
- Conditions
- Cancer, Lung, Cancer, Breast, Cancer Liver, Cancer, Colorectal
- Trial name
- K-DETEK (NCT05227261)
- Where
- Vietnam
- Volunteers
- 9,057 people, healthy volunteers welcome
- Sponsor
- Gene Solutions
Colonic Polyps
GENESIS: Genetic Biopsy for Prediction of Surveillance Intervals After Endoscopic Resection of Colonic Polyps
Colorectal cancer ist the 2nd most leading cancer among men and women in germany. Screening colonoscopy has the potential to detect premalignant lesions.
- Trial name
- GENESIS (NCT02595645)
- Testing
- Polypectomy and NGS
- Where
- 4 sites in Austria, Germany
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Endometrial Adenocarcinoma, Endometrial Carcinoma
Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care
This clinical trial studies universal screening for deoxyribonucleic acid (DNA) mismatch repair deficiency in patients with endometrial cancer, mutations in the genes responsible for Lynch syndrome (inherited forms of endometrial…
- Conditions
- Endometrial Adenocarcinoma, Endometrial Carcinoma, Lynch Syndrome, Relatives
- Trial name
- OPTEC (NCT03460483)
- Testing
- Genetic Counseling, Genetic Testing, Laboratory Biomarker Analysis
- Where
- 9 sites in United States
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Colorectal Cancer, Colorectal Neoplasms
Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia
The investigators aim to evaluate and compare the diagnostic accuracy of FIT and the novel panel of bacterial gene markers (Fn, m3, Ch and Bc) collectively named as M3, in detecting colorectal advanced neoplasia.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenoma
- Trial name
- M3-PRO (NCT05405673)
- Testing
- Fecal immunochemical test (FIT)
- Where
- Hong Kong
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Neoplasms
Outcomes of Disposable Distal Attachment Device (Endocuff and Transparent Plastic Cap) Assisted Colonoscopy
The purpose of the study is to compare the efficacy of device assisted colonoscopy (DAC) with standard colonoscopy (SC) in detecting adenomas in a randomized fashion.
- Trial name
- NCT02504411
- Testing
- Device Assisted Colonoscopy, Standard Colonoscopy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Colorectal Cancer
The Roles of Exosomal Circ-LRBA and 451/CRTC2 Signaling Axis in Colorectal Cancer
Colorectal cancer (CRC) is one of the most common malignant tumors in the world. Most of the patients with colorectal cancer were diagnosed in poor stage.
- Trial name
- NCT05579353
- Testing
- nothing
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jingbo Chen
Colorectal Cancer
Assessment of Glypican 3 as Apredictive Marker in Colorectal Cancer Patients
Evaluation Of Glypican 3 in serum of colorectal cancer patients . Correlation between Glypican 3 and clinicopathological characteristics of colorectal cancer .
- Trial name
- NCT04728139
- Testing
- glypican 3
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Endometrial Cancer, Lynch Syndrome
Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
Study Goal: This pilot study wants to find out if using a menstrual cup can be a good, non-invasive way to collect samples from the lining of the uterus (called the endometrium) to help screen for endometrial cancer.
- Conditions
- Endometrial Cancer, Lynch Syndrome, Screening, Early Detection of Cancer
- Trial name
- SCREEN-CUP (NCT07220239)
- Testing
- Menstrual cup use
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Jessica D. St. Laurent, MD
Colorectal Cancer
The Purpose of This Study is to Determine the Frequency of Colorectal Cancer in Male and Female Endurance Athletes Between the Ages of 35 and 50
The purpose of this study is to determine the frequency of colorectal cancer in male and female endurance athletes between the ages of 35 and 50.
- Trial name
- NCT05419531
- Testing
- prospective observational study - screening and follow up colonoscopy
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Colorectal Cancer
Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer Surgery
Our aim will be to evaluate the efficacy of perioperative Duloxetine in decreasing acute postoperative pain after laparoscopic colorectal cancer surgery and its role in reducing postoperative morphine requirements
- Trial name
- NCT04294953
- Testing
- Duloxetine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colorectal Cancer
Screening for Familial Colorectal Cancer (CRC) Patients
The goal of this psychosocial research study is to learn about the knowledge, beliefs, and attitudes that people have toward screening for colorectal cancer.
- Trial name
- NCT00632515
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Sigmoid Colon Cancer
The Effects of Mechnikov Probiotics on Symptom and Surgical Outcome
The purpose of this clinical trial study was to evaluate the prevalence of colon cancer among the symptom (s) of anterior resection syndrome that may occur after surgery in patients for efficacy and safety in Metchnik probiotic…
- Trial name
- NCT03531606
- Testing
- Mechnicov probiotics
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Kye Bong-Hyeon
Colorectal Neoplasms
Gluteal Squeeze for Left Colon Distension
Good distension of the colon during colonoscopy is essential to detect polyps. Gas sometimes escapes the colon through the anus resulting in compromised distension.
- Trial name
- NCT04827485
- Testing
- Gluteal squeeze, No squeeze
- Where
- 2 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Cancer
Study to Assess Colonic Microbiota Changes in Response to Energy Drink Consumption
This study will investigate whether short-term daily energy drink consumption results in an increase in hydrogen sulfide-producing bacteria in adults 18-40 years old.
- Trial name
- ROSANNA (NCT06137248)
- Testing
- Energy drink
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Florida
Colorectal Neoplasms
Lay Health Workers and Colorectal Cancer Screening Among Chinese Americans
This proposed project seeks to expand understanding of what constitutes a "lay health worker (LHW)," how those characteristics determine the effectiveness of LHWs as health educators on colorectal cancer (CRC) screening, and the…
- Trial name
- NCT00947206
- Testing
- LHWO about CRC, Nutrition Education + CRC brochure
- Where
- 2 sites in United States
- Volunteers
- 909 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Aberrant Crypt Foci
The Effects of Curcuminoids on Aberrant Crypt Foci in the Human Colon
The purpose of this study is to determine the effectiveness of curcumin in reducing the number of aberrant crypt foci (ACF) in the colon.
- Trial name
- NCT00176618
- Testing
- sulindac, curcumin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Dentistry of New Jersey
Colon Cancer
Phase I Biomarker Study of Dietary Grape-derived Low Dose Resveratrol for Colon Cancer Prevention
This study is designed to investigate the dietary influence of grapes in colon cancer prevention. A natural compound found in the skin of grapes, resveratrol, may protect against cancer by acting as an antioxidant (a chemical…
- Trial name
- NCT00578396
- Testing
- grapes
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
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