Clinical trials: Colon Preparation
Polyps, Colon Preparation
Comparison Between Asymmetric And Standard Split-Dose Regimen For Bowel Preparation
We aimed to compare the efficacy for bowel cleansing of a split-dose regimen with a low morning dose of PEG solution (Asymmetric; 25% of the dose is given on the day of the procedure and 75% of the dose is given on the day…
- Trial name
- NCT03146052
- Testing
- PEG-4000 added with citrates and simethicone (PEG-CS) plus Bisacodyl
- Where
- Italy
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- ASST Rhodense
Colon Cancer
BLI850-302: BLI850 vs an Approved Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy
This is a randomized, parallel, multi-center, single-blind study, comparing BLI850 to an FDA approved bowel preparation in adult subjects undergoing colonoscopy.
- Trial name
- NCT00756548
- Testing
- BLI850, polyethylene glycol 3350 based bowel preparation
- Where
- 12 sites in United States
- Volunteers
- 386 people
- Sponsor
- Braintree Laboratories
Colon Cancer, Polyps
Evaluation of Stool Tagging for Improved Patient Compliance
Computed tomography (CT) colonography has gained widespread multi-disciplinary interest as an evolving noninvasive colorectal screening examination, with the potential of improved patient compliance.
- Trial name
- NCT00124163
- Testing
- Imaging procedure of CT colonography
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Center for Diagnostic Imaging
Quality of Bowel Preparation for the Colon Capsule, Colon Capsule Completion Rates
Improving Bowel Preparation for the Colon Capsule
Colon capsule endoscopy is a technology that has been developed as a noninvasive method of examining the large bowel. The biggest limitation to its use has been finding a bowel preparation that will both clean the colon…
- Conditions
- Quality of Bowel Preparation for the Colon Capsule, Colon Capsule Completion Rates, Colon Capsule Polyp Detection
- Trial name
- NCT01655095
- Testing
- PEG, Prucalopride, Picosalax
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Colorectal Surgery
Mechanical Bowel Prep Randomized Study
Following colon surgery, surgical site infection (SSI) is the most common complication and leads to longer recovery time for patients and increased health care costs.
- Trial name
- NCT04931173
- Testing
- IVA+OA versus IVA+MBP+OA
- Volunteers
- 1,062 people
- Sponsor
- Mount Sinai Hospital, Canada
Colorectal Neoplasms
Comparison of the Effectiveness of Bowel Preparations Before Colonoscopy
Polyethylene glycol is the gold standard of bowel preparation for colonoscopy. The most important disadvantage is high volume of this preparation.
- Trial name
- NCT03242369
- Testing
- colonoscopy
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Military University Hospital, Prague
Cleansing Quality of the Colon
Impact of a Predictive Score of Bowel Preparation Quality in Clinical Practice
This is a single center randomized controlled trial to compare the colon cleansing quality determined by the Boston Bowel Preparation Scale achieved by two strategies in patients with high risk of poor colon cleansing defined as…
- Trial name
- REPREP2 (NCT03830489)
- Testing
- polyethylene glycol, polyethylene glycol plus ascorbic acid
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Hospital Universitario de Canarias
Colon Disease
Safety, Efficacy and Tolerability of Bowel Preparation and Colonoscopy in Patient With CHD, CKD and CLD
Consecutive eligible patients will be enrolled and written informed consent will be obtained from all participants. Routine blood investigations will be sent.
- Trial name
- NCT06874036
- Testing
- Colonoscopy
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Asian Institute of Gastroenterology, India
Bowel Cleansing, Colon Capsule Completion Times
Prucalopride + Prucalopride Booster vs. Prucalopride + Picosalax Booster for the Colon Capsule
Colon capsule endoscopy is a new technology that is a noninvasive method of examining the large bowel. The bowel preparation required for this test differs from colonoscopy in that it needs to clean the colon but also needs to…
- Trial name
- NCT01864915
- Testing
- Prucalopride, Colon Capsule
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Queen's University
Colonic Diseases
The Impact of Diet Liberalization on Bowel Preparation for Colonoscopy
This study will evaluate the expansion of dietary options from clear liquids the entire day to a low reside breakfast and lunch for patients prior to undergoing bowel preparation with MoviPrep® and its effect on preparation…
- Trial name
- NCT01876576
- Testing
- Clear liquids, Low residue breakfast and lunch
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Thomas Jefferson University
Colorectal Carcinoma
Comparative Study of Lubiprostone and PEG Preparation Versus Conventional PEG Preparation for Colonoscopy
Lubiprostone as an adjunct to the standard bowel preparation regime the quality of bowel preparation can be improved for a good colonoscopic examination without missing lesions and complications.
- Trial name
- Lubiprostone (NCT01324284)
- Testing
- Lubiprostone
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Colonoscopy Preparation, Colon Disease
Safety and Efficacy of CDFR0612 and CDFR0613 for Bowel Cleansing Before Colonoscopy
The purpose of this study is to evaluate the safety and efficacy of CDFR0612 and CDFR0613 compared to PEG+picosulfate (Coolprep Powder) preparation.
- Trial name
- NCT02304523
- Testing
- CDFR0612, CDFR0613, Coolprep Powder
- Where
- 4 sites in South Korea
- Volunteers
- 310 people
- Sponsor
- CTC Bio, Inc.
Colorectal Cancer, Colonic Adenoma
Bowel Cleansing Performance of the Pure-Vu System in Patients With a History of Poor Bowel Preparation
The diagnostic accuracy and safety of colonoscopy highly depends on the quality of the pre-procedural bowel preparation. A past history of poor bowel preparation is the most important risk factor of inadequate bowel cleansing at…
- Conditions
- Colorectal Cancer, Colonic Adenoma, Bowel Preparation
- Trial name
- NCT04700410
- Testing
- Pure-Vu System
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 44 people
- Sponsor
- Radboud University Medical Center
Colorectal Cancer, Colonoscopy
Fixed Low-dose Simethicone Combined With Macrogol 4000 (PEG) Reduces Colon Bubble Formation in Colonoscopy
Several randomised studies have shown that the addition of low-dose Simethicone to the bowel preparation was sufficient to reduce the presence of bubbles during colonoscopy.
- Conditions
- Colorectal Cancer, Colonoscopy, Bowel Preparation Solution
- Trial name
- XIMEPEG-RL (NCT06319924)
- Testing
- Simethicone combined with Macrogol 4000 (PEG)
- Where
- 5 sites in France
- Volunteers
- 601 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Antibiotic, Bowel Cancer
Mechanical Bowel Preparation With or Without Oral Antibiotics for Colorectal Cancer Surgery
Investigation of the role of adding oral antibiotics to preoperative mechanical bowel preparation before colorectal surgery for cancer.
- Conditions
- Antibiotic, Bowel Cancer, Colorectal Cancer, Surgical Site Infection
- Trial name
- MECCA (NCT03563586)
- Testing
- Bowel Preparation plus antibiotics, Bowel Preparation
- Where
- Greece
- Volunteers
- 210 people
- Sponsor
- National and Kapodistrian University of Athens
Colorectal Cancer, Colon Polyp
Efficacy of Free Versus Low Residue Diet as Preparation for Screening Colonoscopy
One tricky aspect of the recommendations for colonoscopy prep is diet. This has a significant impact on the experience of the patient or participant in the screening program and, on the other hand, low adherence has been found in…
- Conditions
- Colorectal Cancer, Colon Polyp, Colon Adenoma
- Trial name
- CriLi (NCT04664543)
- Testing
- Free diet, Three days low residue diet
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Parc Taulí Hospital Universitari
Quality of Bowel Preparation
Effect of Simethicone on Colon Preparation During Water Exchange Colonoscopy
Background: Colonoscopy reduces colorectal cancer mortality by enabling early detection and removal of adenomas. Its effectiveness, however, depends heavily on bowel preparation quality and mucosal visibility.
- Trial name
- NCT07674160
- Testing
- Simethicone with PEG, PEG
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Colonic Irrigation
Evaluation of Performance and Safety of Colonic Irrigation With the Colon Hydromat as a Non-oral Bowel Preparation for Colonoscopy
This is a clinical study with a medical device that bears the CE mark (approval for marketing in the EU) and is applied within its intended use.
- Trial name
- NCT04684082
- Testing
- Colonic irrigation with the Colon Hydromat
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- Herrmann Apparatebau GmbH
Colon Cancer Screening
An Interactive Video Educational Tool Improves the Quality of Bowel Preparation for Colonoscopy
The investigators aimed to determine whether an interactive, online educational platform could improve procedure show rates and bowel preparation scores in an outpatient population presenting for routine colonoscopy.
- Trial name
- NCT04491565
- Testing
- educational video
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Colon Cancer, Colon Disease
Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in Iberia
A retrospective study to evaluate the effectiveness and safety of 1L polyethylene glycol (PEG)+ Ascorbic acid given for bowel preparation before colonoscopy.
- Conditions
- Colon Cancer, Colon Disease, Colon Cleansing
- Trial name
- NCT05174845
- Testing
- 1L PEG + ASCORBIC ACID
- Where
- 12 sites in Portugal, Spain
- Volunteers
- 13,393 people
- Sponsor
- Norgine