Clinical trials: Colon Rectal Cancer
Colorectal Neoplasms, Colorectal Cancer
Bile Acids and Microbiome in Early Colorectal Carcinogenesis
Currently colorectal cancer pathogenesis is mainly explained by the adenoma-carcinoma sequence theory that was proposed more than half a century ago.
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Colorectal Polyp, Microbiome
- Trial name
- NCT06502704
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Colo-rectal Cancer, Colon Cancer
Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption
Briefly, this is a 28-day dietary intervention study participants will be asked to eat 2 ounces (52 grams) of walnuts every day for 3 weeks, and at the end of the study period they will come in for a colonoscopy.
- Conditions
- Colo-rectal Cancer, Colon Cancer, Diet Habit
- Trial name
- NCT04066816
- Testing
- Walnuts
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- UConn Health
Colo-rectal Cancer
New Genes in the Carcinogenesis of Colorectal Cancer
Colo rectal cancer is one of the greatest ,mutual malignancies worldwide ,accounting for an estimated 1.3 million new cases and >500,000 mortality ⁄ year .
- Trial name
- NCT03261752
- Testing
- blood sample
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colorectal Cancer Screening
FLU-FIT Program at Kaiser Permanente Northern California
The investigators overall goal is to develop, implement, test, and disseminate an intervention to increase colorectal cancer screening rates at Kaiser Permanente (KP) by providing home fecal immunochemical test kits (FIT) to…
- Trial name
- NCT01210235
- Testing
- FLU-FIT Program
- Where
- United States
- Volunteers
- 7,465 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Colorectal Cancer
Child-Physician Recommendation on Parental Adherence to Colorectal Cancer Screening
Physician recommendation has been shown to be one of the most significant predictors for colorectal cancer (CRC) screening. This study aims to identify the amount of parents of internal medicine residents at NYU who are eligible…
- Trial name
- NCT03304860
- Testing
- Survey
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Colorectal Cancer
Colorectal Cancer Screening Assessment Study
This study, led by the American Samoa Community Cancer Coalition's INdigenous Samoan Partnership to Initiate Research Excellence (INSPIRE) and the UH Cancer Center's project team including Dr.
- Trial name
- NCT04500171
- Testing
- Colocare Instruction Sheet: SAM + CAM SMOG, CDC Colorectal cancer screening for life brochure: SAM + CAM SMOG, Colocare Instruction Sheet: SAM + CAM - Superior rating SMOG - 5th Grade Level
- Where
- 2 sites in American Samoa
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Colorectal Cancer
Comparison of NOSES and Conventional Laparoscopic Surgery in Colorectal Cancer
Radical surgery for rectal cancer has evolved from the initial concept of total mesorctal excision (TME) to the wide application of laparoscopic surgery in the radical treatment of rectal cancer.
- Trial name
- NCT04559087
- Testing
- Laparoscopic Surgery
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zunyi Medical College
Colorectal Cancer
Impact of a Proactive Strategy of General Practitioners on CRC Screening
In this registry-based cluster randomized controlled trial, we will assess the impact of a proactive strategy of general practitioners (GP) who will systematically provide screening kits of colorectal cancer (CRC) to all patients…
- Trial name
- DECORE (NCT06664567)
- Testing
- Colorectal cancer screening test
- Volunteers
- 26,260 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Colorectal Carcinoma
Comparative Study of Lubiprostone and PEG Preparation Versus Conventional PEG Preparation for Colonoscopy
Lubiprostone as an adjunct to the standard bowel preparation regime the quality of bowel preparation can be improved for a good colonoscopic examination without missing lesions and complications.
- Trial name
- Lubiprostone (NCT01324284)
- Testing
- Lubiprostone
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Breast Cancer Female, Colorectal Cancer
Increasing Colorectal and Breast Cancer Screening in Women
This study compares the efficacy (adherence and stage) of four interventions to promote colorectal (CRC) and breast cancer (BC) screenings among women ages 50 to 75. They are: 1. usual care; 2.
- Trial name
- COBRA (NCT03279198)
- Testing
- TIWeb, CSC, UC
- Volunteers
- 1,196 people, healthy volunteers welcome
- Sponsor
- Indiana University
CRC
Effect of WhatsApp Messenger on Uptake of CRC Screening Study
It is estimated that there are about 1.4 million patients with colorectal cancer (CRC) worldwide, with a rising trend in CRC incidence in many Asian Pacific countries1.
- Trial name
- NCT03337776
- Testing
- WhatsApp message, Telephone call
- Where
- Hong Kong
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colo-rectal Cancer, Colonic Neoplasms
Effect of Adding Simethicone to Split-dose Polyethylene Glycol for Bowel Preparation in a Screening Colonoscopy Setting
Colonoscopy is currently accepted as the gold standard in screening, surveillance and prevention for colorectal cancer (CRC), and therefore, its quality is a major priority.
- Trial name
- NCT03816774
- Testing
- PEG split-dose and simethicone
- Where
- Portugal
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Colo-rectal Cancer
Safety,Usability and Compliance of Using C-Scan System for Providing Information on Colonic Polypoid Lesions and Masses
Protocol Title: Evaluation of safety, usability and subject compliance while using Check- Cap's C-Scan System for providing structural information on colonic polypoid lesions and masses Study Design: Prospective, Multi-center…
- Trial name
- C-Scan (NCT03735407)
- Testing
- C-Scan procedure
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Colorectal Cancer
Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode
The ECLIPSE (Evaluation of the ctDNA LUNAR test in an Average Patient Screening Episode) study is a prospective, observational multi-site study without randomization.
- Trial name
- ECLIPSE (NCT04136002)
- Where
- 271 sites in United States
- Volunteers
- 44,467 people, healthy volunteers welcome
- Sponsor
- Guardant Health, Inc.
Ovarian Neoplasms, Breast Neoplasms
Establishment of a Tumor Bank for Tissue Samples
Establishment of a tumor bank, consisting of tissue samples of tumor patients (benign and malign tumors) and healthy people as controls.
- Conditions
- Ovarian Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Neoplasms of the Female Genitalia
- Trial name
- NCT01789229
- Testing
- Tumor tissue collection, Sampling of ascites and pleural effusion, Collecting urine samples
- Where
- 3 sites in Austria, Belgium and 1 more
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
Effect of Lidocaine Transdermal Patch as Add-On Therapy in Treatment of Oxaliplatin Induced Peripheral Neuropathy in Colorectal Cancer Patients
Oxaliplatin (OXA) is a third-generation platinum-based chemotherapeutic drug with better efficacy for colorectal carcinoma (CRC).
- Trial name
- NCT05866653
- Testing
- lidocaine transdermal patch
- Where
- Bangladesh
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Colo-rectal Cancer
Blood Collection Sub-Study for CRC Screening in Individuals 45-49 at Average Risk for CRC.
The primary objective of this sub-study, 2018-10B, is to collect blood specimens to assess new biomarkers for the detection of Colorectal Cancer (CRC).
- Trial name
- NCT03741166
- Testing
- Blood Sample Collection
- Where
- 37 sites in United States
- Volunteers
- 871 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colorectal Cancer, Colorectal Neoplasms
Effectiveness of Modified Integrated Colorectal Cancer Screening System in Saudi Arabia
In order to encourage the population at risk to participate in colorectal cancer screening, this clustered trial intends to determine the efficacy of specific messages(Nudge), single FIT testing, and the primary care physician's…
- Trial name
- ColonCancer (NCT05785975)
- Testing
- Certain ommunications(Nudge), community-outreach(landline call), and single FIT testing
- Where
- Saudi Arabia
- Volunteers
- 2,520 people, healthy volunteers welcome
- Sponsor
- The New Model of Care, Hail Health Cluster