Clinical trials: Colonic Disease
Ulcerative Colitis
A Study of LIV001 in Healthy Subjects and Those with Mild-to-Moderate Active Ulcerative Colitis (UC)
This study is only for the first in human phase 1a study designed to investigate the safety and tolerability of LIV001 in healthy participants.
- Trial name
- NCT05975047
- Testing
- LIV001
- Where
- Australia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Liveome Inc.
Prostate Cancer, Colorectal Cancer
Reducing Cancer Disparities for American Indians in the Rural Intermountain West
The purpose of this demonstration is to evaluate the effectiveness of using community outreach workers (navigators) to help American Indians living in rural areas overcome barriers to appropriate cancer screening, diagnosis, and…
- Conditions
- Prostate Cancer, Colorectal Cancer, Breast Cancer, Cervical Cancer
- Trial name
- NCT00380055
- Testing
- Navigation Services, Cancer education
- Where
- 2 sites in United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of Utah
Colorectal Neoplasms
Message Framing and Colorectal Cancer Screening
The main purpose of this study is to promote colorectal cancer (CRC) screening among individuals who have never been screened, with these individuals being members of a panel who participant in online studies.
- Trial name
- CRC (NCT02483832)
- Testing
- Educational materials
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Duke University
Colon Cancer, Colon Sessile Serrated Adenoma/Polyp
Narrow Band Imaging Versus White Light for Colonoscopy Serrate Lesions Detection
Colorectal cancer (CRC) is a leading cause of cancer death and its' incidence is rising in most European countries. Colonoscopy has been shown to reduce CRC incidence, however its effectiveness depends on the sensitivity to…
- Trial name
- NCT02876133
- Testing
- narrow band imaging withdrawal, white light withdrawal
- Where
- 3 sites in Portugal
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo
Cancer Colorectal
Calm for Cancer Patients Receiving Chemotherapy
Chemotherapy is a common strategy used to treat colorectal cancer patients, but is often leads patients and survivors to experience a host of symptoms, of which acute emotional distress is a major concern.
- Trial name
- NCT04345952
- Testing
- Calm Meditation Mobile App
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Colon Cancer
Voyage: Real-World Impact of the Multi-target Stool DNA Test on CRC Screening and Mortality
The purpose of this study is to gather information about the long term health of people who have been prescribed the Cologuard test, which is used for colorectal cancer (CRC) screening.
- Trial name
- NCT04124406
- Testing
- Cologuard
- Where
- United States
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colorectal Cancer
Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery
This is a prospective randomized study to evaluate the difference in the rate of surgical site infection between the patients who used Sodium Picosulfate solution(PicosolutionⓇ) and tablet Oral Sulphate Solution(ORA·FANGⓇ) for…
- Trial name
- NCT04593446
- Testing
- Oral Sulfate Tablet(ORA·FANGⓇ), Sodium Picosulfate Solution(PicosolutionⓇ)
- Where
- South Korea
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Colorectal Cancer
Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk
The overall goal of this study is to develop a comprehensive, culturally tailored community-based colorectal cancer (CRC) prevention model with a dual emphasis on reducing CRC risk along with its CVD risk factors.
- Trial name
- CHURCH (NCT05174286)
- Testing
- SBIRT, Referral as Usual (RAU)
- Where
- United States
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Columbia University
Colorectal Cancer, Colorectal Cancer Screening
Colorectal Cancer Screening Intervention Trial
Colorectal cancer is the second deadliest among cancers and disproportionately affects African Americans. The Colorectal Cancer Screening Intervention Trial(CCSIT) project has as its goal to test three interventions designed to…
- Trial name
- NCT00265720
- Testing
- Control, Reduced out of pocket expense, one on one education
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Irritable Bowel Syndrome
The Effect of Serotonergic Modulation on Intestinal Permeability and Visceral Hypersensitivity in Healthy Individuals and Irritable Bowel Syndrome (IBS) Patients
Serotonin, 5-hydroxytryptamin (5-HT), plays an important role in regulating the gastrointestinal functions. In this study we will modulate the serotonin system with acute tryptophan depletion (ATD) and administration of…
- Trial name
- NCT00731003
- Testing
- Oxitriptan, Acute tryptophan depletion, Amino acid drink with tryptophan
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Colon Cancer, Rectal Cancer
Patient Activation Intervention in Improving Screening Rates for Colorectal Cancer
This randomized clinical trial focused on activating the patient to ask their health care provider for a colorectal cancer screening test to improve screening rates for colorectal cancer.
- Trial name
- NCT01801059
- Testing
- educational intervention, questionnaire administration
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Cancer
Colon Cancer Prevention Study
The goal of this research study is to design messages which can help people learn more about how to prevent colon cancer. Eligible participants will be asked to review a series of short cancer prevention messages and share their…
- Trial name
- NCT00924690
- Testing
- Behavioral Messages, Generic Messages
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Colorectal Cancer
Veteran Primers for CRC Screening
This is a prospective, randomized controlled trial that will evaluate the effectiveness of primer postcards sent two weeks prior to the mailing of a FIT kit in improving adherence to annual CRC screening.
- Trial name
- NCT04923646
- Testing
- Primer
- Where
- United States
- Volunteers
- 2,404 people, healthy volunteers welcome
- Sponsor
- VA Puget Sound Health Care System
Inflammatory Bowel Disease
Long-term Functional Outcome of Children With Inflammatory Bowel Disease
Inflammatory bowel diseases (IBD) are group of immune system disorders characterized by a chronic course with remission and relapses.
- Trial name
- NCT02152241
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Colorectal Cancer, Colorectal Neoplasms
Effectiveness of Modified Integrated Colorectal Cancer Screening System in Saudi Arabia
In order to encourage the population at risk to participate in colorectal cancer screening, this clustered trial intends to determine the efficacy of specific messages(Nudge), single FIT testing, and the primary care physician's…
- Trial name
- ColonCancer (NCT05785975)
- Testing
- Certain ommunications(Nudge), community-outreach(landline call), and single FIT testing
- Where
- Saudi Arabia
- Volunteers
- 2,520 people, healthy volunteers welcome
- Sponsor
- The New Model of Care, Hail Health Cluster
Breast Cancer, Colo-rectal Cancer
The French E3N Prospective Cohort Study
The French E3N cohort was initiated in 1990 to investigate the risk factors associated with cancer and other major non-communicable diseases in women.
- Conditions
- Breast Cancer, Colo-rectal Cancer, Parkinson Disease, Asthma
- Trial name
- E3N (NCT03285230)
- Where
- France
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Colon Cancer, Colon Adenomas
Plasma ctDNA in Patients Undergoing Diagnostic Colonoscopy
When the DNA inside of human cells undergoes certain alterations (mutations), the cells may develop into a cancer. The cancer cells may shed this DNA into the blood stream.
- Conditions
- Colon Cancer, Colon Adenomas, Colon Polyps
- Trial name
- NCT02665299
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Pathway Genomics
Abdominal Pain, Diarrhea
The Clinical Application of MCCES in Examination of Human Colon
This study is to determine the feasibility and safety of magnetic-controlled capsule endoscopy system in examination of human colon under the real time monitoring by colonoscopy in the clinical application.
- Conditions
- Abdominal Pain, Diarrhea, Hematochezia
- Trial name
- NCT02536144
- Testing
- magnetic-controlled capsule endoscopy system, Colonoscopy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Colonic Neoplasms
Right-sided Retroflexion With Standard Adult Versus Pediatric Colonoscopes
Screening colonoscopy has been shown to be less effective in preventing colorectal cancer in the proximal colon compared to the distal colon.
- Trial name
- NCT01675934
- Testing
- Retroflexion with the adult colonoscope., Retroflexion with the pediatric colonoscope.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Analysis of Microbiota Changes Induced by Microencapsulated Sodium Butyrate in Patients With Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is characterized by severe inflammation of the small bowel and/or the colon leading to recurrent diarrhea and abdominal pain.
- Trial name
- IBDMicro (NCT04879914)
- Testing
- Butyrate
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Padova
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