Clinical trials: Colonic Diverticulosis
Diverticular Disease of Colon, Diverticulosis, Colonic
Prevalence of Segmental Colitis Associated With Colic Diverticulosis (SCAD)
Colonic diverticula are common in Western countries, affecting up to 60% of subjects over 70 years of age. In about 80% of patients, colonic diverticula remain asymptomatic (diverticulosis), while approximately 20% of patients…
- Trial name
- NCT04279821
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
Gastrointestinal Neoplasia, Hirschsprung's Disease
Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy
To test the idea that submucosal endoscopy is effective and safe for endoscopic myotomy, endoscopic submucosal dissection, and access for tissue acquisition and resection.
- Conditions
- Gastrointestinal Neoplasia, Hirschsprung's Disease, Esophageal Obstruction, Gastroparesis
- Trial name
- NCT03626350
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver
Diverticular Disease of Colon, Quality of Life
PREDICtors for Quality of Life After Sigmoidectomy for DIVerticular Disease
To identify predictors for postoperative health related quality of life after elective sigmoidectomy for diverticular disease.
- Trial name
- PREDIC-DIV (NCT03527706)
- Where
- Germany
- Volunteers
- 165 people
- Sponsor
- Städtisches Klinikum München GmbH
Diverticular Disease of Left Side of Colon
Quality of Life (QOL) After Elective Sigmoidectomy for Diverticular Diseases (DIVERTI)
Acute diverticulitis of the left colon is among the most common abdominal disorders. To date, both conservative therapy in uncomplicated stages and emergency surgery in perforated disease with peritonitis are consensual.
- Trial name
- DIVERTI-QDV (NCT04730765)
- Testing
- left elective colectomy (Surgical Experimental Group), antibiotic therapy (medical Control Group)
- Volunteers
- 220 people
- Sponsor
- University Hospital, Caen
Colonic Diverticula, Diverticulitis
Pathophysiology of Diverticular Disease
Colonic diverticular disease is a highly prevalent condition in Western populations. The prevalence increases age-dependently from 5% at 40 years to 65% by the age of 85 years (1-3). The majority remain asymptomatic.
- Trial name
- NCT01493349
- Where
- Netherlands
- Volunteers
- 210 people
- Sponsor
- Maastricht University Medical Center
Defecatory Disorders After Left Colonic or Rectal Resection
Improvement of Anorectal Function While Preserving of Inferior Mesenteric Artery Performing Left Hemicolectomy for Diverticulosis
The aim of the study is to evaluate the anorectal function after hemicolectomy if we preserve or not the Inferior Mesenteric Artery (IMA).
- Trial name
- IPIMAL (NCT01326052)
- Testing
- Inferior Mesenteric Artery Preservation, Inferior Mesenteric Artery Ligation
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Roma La Sapienza
Diverticulosis, Colonic, Microbiota
Influence of Mechanical Bowel Preparation on GI Microbiota
The mechanical bowel preparation (BP) used to clean the colon prior to colonoscopy frequently results in a significant but temporary reduction in patient's symptoms for a number of bowel disorders including symptomatic…
- Trial name
- NCT03465293
- Testing
- Bacterial composition and activity after bowel preparation
- Volunteers
- 15 people
- Sponsor
- University of Reading
Colonic Cancer, Rectal Cancer
Transversus Abdominis Plane (TAP) Block for Postoperative Analgesia After Laparoscopic Colonic Resection
Laparoscopic (key-hole) large bowel resection is a minimally invasive procedure when compared to open large bowel resection, but is still associated with a significant amount of pain and discomfort.
- Conditions
- Colonic Cancer, Rectal Cancer, Colonic Diverticulum, Ulcerative Colitis
- Trial name
- NCT01339273
- Testing
- Ultrasound guided Transversus Abdominis Plane (TAP) bock, Local anaesthetic infiltration of laparoscopic port sites
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- Oxford University Hospitals NHS Trust
Colonic Diverticula
Predictive Value of DICA in the Diverticular Disease of the Colon
The Diverticular Inflammation and Complication Assessment (DICA) is an endoscopic classification for diverticulosis and diverticular disease of the colon.
- Trial name
- NCT02758860
- Testing
- Colonoscopy
- Where
- 45 sites in Brazil, Italy and 5 more
- Volunteers
- 2,215 people
- Sponsor
- University of Roma La Sapienza
Diverticulum, Colon, Diverticulitis
Registro Malattia Diverticolare (Registry of Diverticular Disease)
To determine the clinical characteristics and risk factors for the onset of diverticular disease and its complications in the Italian population.
- Trial name
- REMAD (NCT03325829)
- Volunteers
- 1,217 people
- Sponsor
- Gruppo Italiano Malattia Diverticolare
Colonic Neoplasms, Colonic Diverticulosis
Outpatient Left Laparoscopic Colectomy
The success of the enhanced recovery program after surgery leads us to consider outpatient management of the colectomy. To this end, the investigators have designed an observational and prospective study of left laparoscopic…
- Trial name
- COATI (NCT04310839)
- Testing
- Colectomy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Sigmoid Cancer, Sigmoid Diverticulosis
Comparison of Quality of Life and Functionnal Resultats After Sigmodectomy Between Diverticulitis and Cancer
The aim of this present study is to compare functional results and quality of life after sigmoidectomy for diverticulitis and sigmoid cancer.
- Trial name
- SIG-QOL (NCT04729283)
- Testing
- Sigmoidectomy
- Where
- 4 sites in France
- Volunteers
- 94 people
- Sponsor
- Nantes University Hospital
Colonic Diverticula, Angiodysplasia
Study of Hemospray for Lower Gastrointestinal Hemorrhage
This study is to evaluate the performance of Hemospray for the teatment of nonvariceal lower gastrointestinal bleeding.
- Conditions
- Colonic Diverticula, Angiodysplasia, Colonic Polyp
- Trial name
- NCT02099435
- Testing
- Hemospray
- Where
- 4 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Cook Group Incorporated
Diverticulitis, Diverticulitis Colon
Management and Evolution of Acute Diverticulitis With Pericolic Free Gas
The severity of diverticulitis is usually graded with the use of modified Hinchey Criteria. However, there is a condition often seen in the CT scan that is not included in this classification itself; 1-2 pericolic bubbles but no…
- Conditions
- Diverticulitis, Diverticulitis Colon, Diverticulitis; Perforation, Bowel, Diverticulitis of Sigmoid
- Trial name
- ADiFas (NCT04311385)
- Testing
- CT imaging
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital Central de la Defensa Gómez Ulla
Diverticulitis, Colonic, Therapy
Probiotic After Acute Colonic Diverticulitis
The goal of this observational study is to assess the efficacy and safety of the probiotic Escherichia coli Nissle 1917 (EcN®, Ca.Di.Group S.p.A) in the treatment of symptomatic patients after an episode of both complicated and…
- Trial name
- NCT06040515
- Testing
- Probiotic Formula
- Where
- 12 sites in Italy
- Volunteers
- 145 people
- Sponsor
- Erasmo Spaziani
Simple Diverticular Disease
Randomized Clinical Trial for the Uncomplicated Diverticulitis in Right Colon
The aim of the present study was to evaluate whether antibiotics is mandatory for the treatment of acute uncomplicated right-sided diverticulitis.
- Trial name
- NCT02314013
- Testing
- Cephalosporin + Metronidazole
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Dongtan Sacred Heart Hospital
Diverticular Disease of Colon
Molecular and Microbiota Signatures Underlying Colonic Diverticular Disease
The pathogenesis of diverticular disease is likely multifactorial in origin. This project aims to study the involvement of environmental factors in the pathophysiology of diverticular disease, the underlying molecular mechanisms…
- Trial name
- GR-Barbaro (NCT06764550)
- Testing
- This is an observational study, participants are not assigned an intervention as part of the study.
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Colo-rectal Cancer, Colo-rectal Surgery
Post Operative Hospital at Home After Colorectal Surgery
The goal of this feasibility study is to investigate whether a virtual Hospital at Home is safe and possible for patients undergoing planned minimally invasive colorectal surgery.
- Conditions
- Colo-rectal Cancer, Colo-rectal Surgery, Colocolic and Ileocolic Anastomosis, Colon and/or Rectal Resection With Anastomosis for Cancer
- Trial name
- POPHaH (NCT07113717)
- Testing
- virtual Hospital at Home
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Nordsjaellands Hospital
Diverticulitis, Colonic
Unexpected Diagnosis in Right Lower Quadrant Pain: Right Colon Diverticulitis
BACKGROUND: Acute right lower quadrant pain is a common symptom in emergency departments. The most common etiology is thought to be acute appendicitis. Other etiologies may be overlooked.
- Trial name
- NCT06153030
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Colorectal Cancer, Colorectal Anastomosis
Single-Stapled Technique for Colorectal Anastomosis
The goal of this observational multicenter study is to evaluate the safety and feasibility of a single-stapled technique (SST) for colorectal anastomosis and to explore whether this technique is associated with a reduced rate of…
- Conditions
- Colorectal Cancer, Colorectal Anastomosis, Anastomotic Leakage, Diverticular Disease of Left Side of Colon
- Trial name
- SST (NCT07417358)
- Testing
- Single-stapled colorectal anastomosis, Double-stapled colorectal anastomosis
- Where
- 5 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University