Clinical trials: Colonoscopy Procedure
Colorectal Cancer
Virtual Colonoscopy Using Omnipaque as a Contrast Agent
CT colonography (CTC) is a validated screening exam for colorectal cancer. The diagnostic accuracy of CTC depends on the quality of the bowel cleansing and contrast tagging of residual stool and fluid.
- Trial name
- NCT04582500
- Testing
- Iohexol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Patient Comfort
Development and Validation of the Saint Paul's Endoscopy Comfort Scale (SPECS) for Colonoscopy and Upper Endoscopy
The investigators created the St. Paul's Endoscopy Comfort Score (SPECS) which includes the frequency of verbal cues, body positioning and anxiety levels with descriptions for each of the variables.
- Trial name
- NCT02443480
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- University of British Columbia
Anxiety, Colonoscopy
Effect of Aromatherapy on Anxiety in Colonoscopy Patients
The aim of this study is to investigate the effects of aromatherapy with lavender and bergamot essential oils on anxiety, vital signs, and feelings of embarrassment before colonoscopy.
- Conditions
- Anxiety, Colonoscopy, Aromatherapy
- Trial name
- NCT07067424
- Testing
- Lavender Aromatherapy, Bergamot Aromatherapy
- Where
- Cyprus
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
The Effect of Audio-visual Aids on Bowel Cleanliness, Audiovisual Aids
Visual Aids for Colonoscopy Preparation: A Prospective Study on Patient Understanding and Bowel Cleanliness in Colonoscopy Patients
Effective communication in healthcare is critical for improving patient outcomes, particularly in enhancing health literacy and enabling informed decision-making.
- Trial name
- VACP (NCT07155603)
- Testing
- Animated Video Group 1
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Prof. Dr. Jörg Leuppi
Colonoscopy, Bowel Preparation Solutions
Electrolyte Beverage Combined With Polyethylene Glycol for Colonoscopy Bowel Preparation
This randomized controlled trial aims to evaluate the effects of different ratios of electrolyte beverage and water combined with polyethylene glycol (PEG) on bowel preparation quality before colonoscopy.
- Conditions
- Colonoscopy, Bowel Preparation Solutions, Colorectal Cancer Screening
- Trial name
- NCT07608120
- Testing
- PEG With Water, PEG With Low-dose Electrolyte Beverage, PEG With Medium-dose Electrolyte Beverage
- Where
- China
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Pain
Comparison of Colonoscopy and Sigmoidoscopy in Terms of Pain, Acceptance and Procedure Time
According to experience in a self-payed health check-up center,unsedated total colonoscopy is not inferior or may be better than unsedated sigmoidoscopy in terms of pain and patients' acceptance.
- Trial name
- NCT00302679
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Lynch Syndrome, Hereditary Nonpolyposis Colorectal Cancer
Liquid Biopsy Biomarkers for Endoscopic Surveillance in Lynch Syndrome
Lynch syndrome (LS) is an autosomal dominant hereditary condition that markedly increases the risk of colorectal cancer (CRC) and other malignancies.
- Conditions
- Lynch Syndrome, Hereditary Nonpolyposis Colorectal Cancer, HNPCC, Colorectal Cancer (CRC)
- Trial name
- BioLynch (NCT07838246)
- Testing
- Study procedures
- Where
- Italy
- Volunteers
- 109 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Colonoscopy
Evaluation of Oral Simethicone With Low Volume Polyethylene Glycol Bowel Preparation During Colonoscopy
An adequate bowel preparation has been well established to lead to a successful colonoscopy. Research has consistently demonstrated inadequate bowel preparation with lower adenoma detection rates.
- Trial name
- NCT03410524
- Testing
- Simethicone Solution, Water
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Nevada, Reno
Colonoscopy
Chromoendoscopy in Inflammatory Bowel Disease
Patients with longstanding ulcerative colitis (inflammatory bowel disease, IBD) have increased risk of developing colorectal cancer (CRC) when compared with that of the general population.
- Trial name
- NCT03250780
- Testing
- indigo-carmine 0.2% using a spray catheter, 0.03% using a foot pump
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Colorectal Cancer
Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
Colorectal cancer is a leading cause of cancer death. Detection and removal of polyps can reduce risk for developing colorectal cancer. After finding and removing precancerous polyps, repeat colonoscopy is routinely recommended.
- Trial name
- SOA (NCT05994482)
- Testing
- adenoma vs no adenoma, colonoscopy vs no colonoscopy, survey and expert panel
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Colorectal Cancer
Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)
Colorectal cancer (CRC) is currently the second most common cause of cancer death in the United States, and one of the most preventable cancers.
- Trial name
- CONFIRM (NCT01239082)
- Testing
- Colonoscopy, Fecal immunochemical test (FIT)
- Where
- 46 sites in United States, Puerto Rico
- Volunteers
- 50,126 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Position, Colonoscopy
Dynamic Position Change in Colonic Adenoma Detection
There was an only single operator study reporting dynamic position change during colonoscopy withdrawal significantly improved polyp and adenoma detection.
- Conditions
- Position, Colonoscopy, Adenoma
- Trial name
- NCT01366079
- Testing
- Position change, Left lateral
- Where
- South Korea
- Volunteers
- 1,072 people
- Sponsor
- The Catholic University of Korea
Colorectal Cancer
Outcomes of Patients Who Had an Incomplete Colonoscopy After a Positive Fecal Immunological Test
In France, colorectal cancer (CRC) is the second leading cause of cancer death. Its organized screening (Organized ColoRectal Cancer Screening: DOCCR), now carried out by immunological test for occult blood in the stool, has…
- Trial name
- ColonoScopy (NCT05172713)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Colorectal Cancer
Text Messaging to Improve Adherence To Repeat Colonoscopy In a Veterans Affairs (VA) Hospital
Colorectal cancer is a common but preventable condition, and increasing colorectal cancer screening is one of the most impactful public health contributions in the field of gastroenterology.
- Trial name
- NCT06185374
- Testing
- Text Message Instructions/Motivation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colonoscopy
Study 301: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
The purpose of this study is to compare the safety and efficacy of BLI4900 bowel preparation to an FDA-approved control as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT04446299
- Testing
- Bowel Prep
- Where
- 25 sites in United States
- Volunteers
- 519 people
- Sponsor
- Braintree Laboratories
Gastrointestinal Diseases, Colorectal Cancer
Optimizing the Preparation Regime Prior to Colonoscopy Procedure With Pure-Vu System
The primary objective of this multicenter, prospective, randomized study is to evaluate the performance of Pure-Vu System in cleansing patients' colon who are indicated for a colonoscopy procedure using one of two different…
- Trial name
- NCT03493009
- Testing
- Pure-Vu System
- Volunteers
- healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Colorectal Adenoma, Colorectal Polyp
Examining Techniques on Adenoma Miss Rate in Proximal Colon
The primary aim of this study is to explore the usefulness of re-examination and retroflexion on adenoma miss rate (AMR) in the proximal colon.
- Trial name
- SINOCOLO2017 (NCT03355443)
- Testing
- Retroflexion, Re-examination
- Where
- 3 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Inflammatory Bowel Diseases, Colitis, Ulcerative
Lipid Mediators in Colonic Biopsies as Biomarkers of Disease Activity of Inflammatory Bowel Diseases
We will quantify one of the lipid compounds (5,6 epoxy eicosatrienoic acid (5,6 EET), 5,6- EpoxyEicosaTrienoic acid) in colonic biopsies of Inflammatory Bowel Disease patients.
- Conditions
- Inflammatory Bowel Diseases, Colitis, Ulcerative, Crohn Disease
- Trial name
- MICILIP (NCT01990716)
- Testing
- Colonic Biopsy
- Where
- France
- Volunteers
- 124 people
- Sponsor
- University Hospital, Toulouse
Bubbles in Colon at Time of Colonoscopy
The Effects of Moviprep With Simethicone on Colonic Bubbles
The purpose of this study is to determine whether the administration of PEG along with simethicone will reduce the incidence of colonic bubbles that interfere with polyp detection.
- Trial name
- NCT01209806
- Testing
- simethicone
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Thomas Jefferson University
Colorectal Neoplasms
Study of Narrow Band Imaging in the Characterization of Residual Neoplasia After Endoscopic Piecemeal Mucosal Resection
This study is designed to evaluate the diagnostic accuracy of Narrow Band Imaging (NBI) compared with High Definition White Light colonoscopy (WLE) for detection of residual neoplasia in subjects with piecemeal polypectomy scars.
- Trial name
- CROMOPIE (NCT02448693)
- Testing
- WLE, NBI
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Parc de Salut Mar
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