Clinical trials: Colonoscopy Procedure
Colorectal Cancer
I-Scan Versus High-definition White Light
The purpose of the study is to assess whether the use of I-scan during colonoscopy leads to an increased yield of adenomas in the colon among a population at increased risk for CRC.
- Trial name
- NCT01617278
- Testing
- I-Scan 1, HD Colon, I-Scan 2
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Health Behavior
Effect of Single Dose of 2L PEG on Bowel Preparation in Average-risk Patients Undergoing Colonoscopy
Adequate quality of bowel preparation(BP) is important for colonoscopy. Several guidelines recommend that split-dose of 4L PEG should be used as a standard regime for BP.
- Trial name
- NCT02998255
- Testing
- Single dose of 2L PEG, Split dose of 4L PEG
- Where
- 3 sites in China
- Volunteers
- 940 people
- Sponsor
- Air Force Military Medical University, China
Acute Lower Gastrointestinal Bleeding
Oral PEG vs. Enema in Urgent Colonoscopy for ALGIB
The main goal of this study is to assess whether the diagnostic efficacy of enema is non-inferior to that of oral polyethylene glycol (PEG) in acute lower gastrointestinal bleeding (ALGIB) patients requiring urgent colonoscopy.
- Trial name
- CANDLE (NCT06254443)
- Testing
- Enema Bowel preparation, PEG Bowel preparation
- Where
- 3 sites in China
- Volunteers
- 144 people
- Sponsor
- Beijing Friendship Hospital
Screening Colonoscopy, Surveillance Colonoscopy
Evaluation of Proposed EZ2go Complete Bowel Cleansing System
This study aims to provide safety and efficacy data comparable to available over-the-counter bowel preparations prior to colonoscopy.
- Conditions
- Screening Colonoscopy, Surveillance Colonoscopy, Colonoscopy
- Trial name
- NCT01838408
- Testing
- Ez2go Complete, LoSo Prep
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Borland-Groover Clinic
Glycopyrrolate, Colonoscopy
Antiperistaltic Effect and Safety of Glycopyrronium for Colonoscopic Polypectomy
The purpose of this study is to determine the antiperistaltic effect and safety of glycopyrrolate and whether the use of glycopyrrolate is beneficial for colonoscopy and colonoscopic polypectomy.
- Trial name
- NCT06041984
- Testing
- Glycopyrrolate
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jie Chen
Colonic Neoplasm
Narrow Band Imaging for Diagnosis of Proximal Serrated Polyps
Although colonoscopy is considered the gold standard for diagnosis of colonic polyps, the missed rate for colonic adenoma ranged from 15-32%.
- Trial name
- NCT01725321
- Testing
- Narrow band imaging
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colonoscopy Training
Colonoscopy TRaining With or Without Artificial INtelligence Among Endoscopy Residents
Type of study: Randomized controlled study Investigated Procedure: Artificial Intelligence Software for Polyp Detection in Colonoscopy training Trial participants: Endoscopy trainees during their training with at least one year…
- Trial name
- c-TRAINER (NCT07420309)
- Testing
- Artificial Intelligence in colonoscopy, Conventional colonoscopy training
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Colorectal Cancer
Is Barium Enema an Adequate Diagnostic Test for Patients With Positive FOBT?
The research protocol aim is to compare diagnostic tools for the proper evaluation of patient with fecal occult blood test positive (FOBT +), a routine screening test for colorecatl carcinoma.
- Trial name
- DCBE (NCT00619814)
- Testing
- Double-contrast Barium enema, colonoscopy
- Volunteers
- 50 people
- Sponsor
- VA Caribbean Healthcare System
Colorectal Cancer, Breast Cancer
Screening Colonoscopy in Breast Cancer Patients
Breast cancer survivors may be at increased risk for developing colorectal polyps and colorectal cancer because of shared genetic, hormonal, and lifestyle-related risk factors.
- Conditions
- Colorectal Cancer, Breast Cancer, Colorectal Adenoma
- Trial name
- NCT07678099
- Testing
- Screening colonoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Colonoscopy, Colon Polyps
A Study of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Elderly Patients Undergoing Elective Colonoscopy
This study was designed to demonstrate that AQUAVAN® is effective in providing adequate sedation in elderly patients undergoing colonoscopy as well as to assess the safety profile of AQUAVAN versus that of midazolam.
- Trial name
- NCT00209599
- Testing
- fospropofol disodium
- Volunteers
- 100 people
- Sponsor
- Eisai Inc.
Bowel Cancer Screening, Analgesia
Optimizing the Use of Entonox® During Screening Colonoscopy
This study will randomise patients undergoing screening colonoscopy to receive Entonox either continuously or as required. Both these methods are used in the published studies of Entonox and in clinical practice.
- Conditions
- Bowel Cancer Screening, Analgesia, Entonox, Colonoscopy
- Trial name
- NCT01865721
- Testing
- Entonox
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Bowel Preparation
A Phase 3 Clinical Trials for Bowel Preparation for Colonoscopy
A prospective randomized study compared to the active control. Researchers compare colon cleansing in patients undergoing colonoscopy
- Trial name
- NCT06287606
- Testing
- CTP0302-A, CTP0302-B, Conventional OST
- Where
- South Korea
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Diagnosis Disease
Efficacy, Safety and Tolerability of a New Bowel Cleansing Preparation (BLI800) in Adult Subjects Undergoing Colonoscopy
The purpose is to demonstrate that BLI800 is non-inferior, on overall colon cleansing, to Fortrans® (a reference colonic lavage in China) administered in adult subjects scheduled to undergo a colonoscopy for a routinely accepted…
- Trial name
- EASY (NCT03562884)
- Testing
- BLI800, Fortrans®
- Where
- 10 sites in China
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Ipsen
Colorectal Cancer
Lifestyle Intervention After Colonoscopy (LIFE-SCREEN Pilot)
The study aims to evaluate the impact of promoting advice on the latest evidence-based diet and lifestyle recommendations for cancer prevention at colorectal cancer (CRC) screening among individuals who may be at higher risk for…
- Trial name
- NCT05273931
- Testing
- Lifestyle intervention
- Where
- 2 sites in France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Colorectal Cancer, Screening
Information About a Doctor or a Possibility of Choosing Doctor's Gender and Attendance to Screening Colonoscopy
The purpose of the study is to investigate whether the information about a doctor or possibility to choose doctor's gender included in invitation letter is associated with attendance rate to screening colonoscopy.
- Trial name
- NCT01182922
- Testing
- Invitation letter
- Where
- Poland
- Volunteers
- 5,100 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Resect and Discard Strategies for Colonoscopy
Narrow Band Imaging in the Prediction of Surveillance Intervals After Polypectomy in Community Practice: Ready for (a European) Prime Time
Several reports have suggested that an endoscopic diagnosis of adenoma, by means of narrow band imaging (NBI), might allow the determination of polyp management and surveillance interval, particularly in patients with diminutive…
- Trial name
- NCT02196402
- Where
- Italy
- Volunteers
- 280 people
- Sponsor
- Valduce Hospital
Sedation
Multiple Dose Safety and Efficacy Study Evaluating CNS 7056 Versus Midazolam in Patients Undergoing Colonoscopy
The purpose of this dose-response study is to assess the safety and efficacy of CNS 7056 compared with midazolam to maintain suitable sedation levels in patients undergoing colonoscopy.
- Trial name
- NCT01145222
- Testing
- A. CNS 7056, B. CNS 7056, C. CNS 7056
- Where
- 9 sites in United States
- Volunteers
- 162 people
- Sponsor
- Paion UK Ltd.
Ulcerative Colitis
Comparison Between Chromoendoscopy and Conventional Colonoscopy to Improve the Detection of Neoplasia in Patients With Ulcerative Colitis (UC)
The primary endpoint of the study will be to compare the accuracy of two procedures (FICE with target biopsies only, versus conventional white light colonoscopy with recommended targeted and random biopsies) in the endoscopic…
- Trial name
- NCT00816491
- Testing
- conventional white light colonoscopy, FICE (Fujinon Intelligent Chromoendoscopy)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Colonoscopy, Bowel Preparation
Clinical Study to Evaluate the Efficacy and Safety of GNS-212-E in Bowel Preparation for Colonoscopy
This is a prospective, randomized, single-blind, parallel, active-controlled, and multi-center Phase III clinical trial.
- Trial name
- GNS-212-E (NCT06317350)
- Testing
- GNS-212-E1, GNS-212-E2, GNS-212-ER
- Where
- South Korea
- Volunteers
- 318 people
- Sponsor
- Gunkang Pharmaceuticals, Inc
Adenoma, Pain
Water Method in Elder Patients With Unsedated Colonoscopy
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Trial name
- NCT01546220
- Testing
- Water colonoscopy
- Where
- China
- Sponsor
- Air Force Military Medical University, China
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